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    • 21. 发明申请
    • MODULAR COCHLEAR IMPLANT SYSTEMS INCLUDING IMPLANTABLE SOUND PROCESSORS
    • 模块化COCHLEAR植入系统,包括可植入的声处理器
    • US20100198303A1
    • 2010-08-05
    • US12696275
    • 2010-01-29
    • Matthew I. HallerLeonid M. LitvakAbhijit Kulkarni
    • Matthew I. HallerLeonid M. LitvakAbhijit Kulkarni
    • A61F11/04A61N1/36
    • A61N1/36032A61N1/36036A61N1/372A61N1/37229A61N1/3787
    • Exemplary cochlear implant systems include an implantable head module configured to be implanted within a head of a patient. The implantable head module includes a cochlear stimulator configured to be coupled to an electrode lead, the electrode lead including one or more electrodes configured to be in communication with one or more stimulation sites within the patient. The implantable head module also includes a signal receiver configured to receive a telemetry signal representative of an audio signal from a signal transmitter located external to the patient, a sound processor configured to process the telemetry signal and direct the cochlear stimulator to generate and apply electrical stimulation representative of the audio signal to the one or more stimulation sites via the electrode lead, and a power receiver configured to receive power for operating the implantable head module from a power transmitter located external to the patient.
    • 示例性的耳蜗植入物系统包括被配置为植入患者的头部内的可植入头部模块。 可植入头模块包括被配置为耦合到电极引线的耳蜗刺激器,所述电极引线包括被配置为与患者内的一个或多个刺激部位连通的一个或多个电极。 可植入头模块还包括信号接收器,其被配置为从位于患者外部的信号发射器接收代表音频信号的遥测信号;声音处理器,被配置为处理遥测信号并引导耳蜗刺激器产生并施加电刺激 通过电极引线将音频信号代表到一个或多个刺激部位;以及功率接收器,被配置为从位于病人外部的功率发射器接收用于操作可植入头部模块的功率。
    • 22. 发明授权
    • Level-dependent stimulation methods and systems
    • 水平依赖性刺激方法和系统
    • US07769467B1
    • 2010-08-03
    • US12022968
    • 2008-01-30
    • Gulam EmadiLeonid M. Litvak
    • Gulam EmadiLeonid M. Litvak
    • A61N1/00
    • A61N1/323A61N1/36036A61N1/372
    • Methods of applying stimulation to a stimulation site within a patient include applying stimulation current to the stimulation site via at least one stimulating electrode, applying compensating current configured to affect at least one excitation field caused by the stimulation current via one or more additional electrodes, and dynamically adjusting the compensating current as a function of an amplitude of the stimulation current. Systems for applying stimulation to a stimulation site within a patient include an implantable stimulator, at least one stimulating electrode electrically coupled to the implantable stimulator, and one or more additional electrodes electrically coupled to the implantable stimulator. The stimulator is configured to apply stimulation current to the stimulation site via the at least one stimulating electrode, apply compensating current configured to affect at least one excitation field caused by the stimulation current via the one or more additional electrodes, and dynamically adjust the compensating current as a function of an amplitude of the stimulation current.
    • 将刺激应用于患者内的刺激部位包括通过至少一个刺激电极向刺激部位施加刺激电流,施加配置成影响由一个或多个附加电极引起的刺激电流的至少一个激励场的补偿电流,以及 根据刺激电流的幅度动态地调节补偿电流。 将刺激施加到患者内的刺激部位的系统包括可植入刺激器,电耦合到可植入刺激器的至少一个刺激电极以及电耦合到可植入刺激器的一个或多个附加电极。 刺激器被配置为经由至少一个刺激电极将刺激电流施加到刺激部位,施加配置成影响由一个或多个附加电极的刺激电流引起的至少一个激励场的补偿电流,并且动态地调整补偿电流 作为刺激电流的幅度的函数。
    • 23. 发明申请
    • COMPENSATION CURRENT OPTIMIZATION FOR COCHLEAR IMPLANT SYSTEMS
    • COCHLEAR植物系统的补偿电流优化
    • US20100161000A1
    • 2010-06-24
    • US12644350
    • 2009-12-22
    • Leonid M. LitvakAniket Saoji
    • Leonid M. LitvakAniket Saoji
    • A61N1/36
    • A61N1/36032A61N1/0541A61N1/36036
    • An exemplary cochlear stimulation method includes applying a main current to a first electrode associated with a first pitch and disposed within a cochlea of a patient, concurrently applying a compensation current to a second electrode disposed within the cochlea and associated with a second pitch during the application of the main current, the compensation current being out-of-phase with the main current, and optimizing an amount of the compensation current to result in a target pitch being presented to the patient that is distanced from the first pitch in a pitch direction opposite a pitch direction of the second pitch in relation to the first pitch. Corresponding methods and systems are also disclosed.
    • 示例性的人工耳蜗刺激方法包括将主电流施加到与第一间距相关并设置在患者的耳蜗内的第一电极,同时向施加在耳蜗内的第二电极施加补偿电流并在施加期间与第二间距相关联 的主电流,补偿电流与主电流异相,并且优化补偿电流的量以导致目标音调被呈现给相对于俯仰方向与第一音调远离第一音调的患者 相对于第一间距的第二间距的俯仰方向。 还公开了相应的方法和系统。
    • 24. 发明授权
    • Bionic ear implant
    • 仿生耳植入
    • US07636603B1
    • 2009-12-22
    • US11428302
    • 2006-06-30
    • Edward H OverstreetMichael A Faltys
    • Edward H OverstreetMichael A Faltys
    • A61N1/36
    • A61N1/36036A61N1/0541
    • A bionic ear cochlear stimulation system has the capability to stimulate fast enough to induce stochastic neural firing, thereby acting to restore “spontaneous” neural activity. Such neurostimulation involves the use of a high rate pulsitile stimulation signal that is amplitude modulated with sound information. Advantageously, by using such neurostimulation, a fitting system may be utilized that does not normally require T-level threshold measurements. T-level threshold measurements are not required in most instances because the high-rate pulsitile stimulation, even though at levels that would normally be a sub-threshold electrical stimulus, is able to modulate neural firing patterns in a perceptible way.
    • 仿生耳蜗耳刺激系统具有刺激足够快以诱导随机神经发射的能力,从而起到恢复“自发”神经活动的作用。 这种神经刺激涉及使用用声音信息进行幅度调制的高速率脉动刺激信号。 有利地,通过使用这种神经刺激,可以采用通常不需要T级阈值测量的拟合系统。 在大多数情况下,不需要T级阈值测量,因为即使在通常为亚阈值电刺激的水平下,高速率脉动刺激能够以可察觉的方式调节神经发射模式。
    • 28. 发明授权
    • Inner hair cell stimulation model for the use by an intra-cochlear implant
    • 用于耳蜗内植入物的内毛细胞刺激模型
    • US07522961B2
    • 2009-04-21
    • US10992390
    • 2004-11-17
    • Gene Y. FridmanLeonid M. Litvak
    • Gene Y. FridmanLeonid M. Litvak
    • A61N1/08G10L21/00H04R25/00
    • A61N1/36032A61N1/36036
    • The stimulation provided in the electrically stimulated cochlea is modulated in accordance with the amplitude of a received acoustic signal and the onset of a sound in a received acoustic signal to provide increased sound perception. An onset time that corresponds to the onset of a sound is detected in an acoustic signal associated with a frequency band. A forcing voltage and a transmitting factor are determined, wherein the forcing voltage and the transmitting factor are associated with the frequency band at the detected onset time. The acoustic signal is modulated as a function of the forcing voltage and the transmitting factor to generate an output signal. The generated output signal can be used to stimulate the cochlea. The modulation strategy can be used in conjunction with sound processing strategies that employ frequency modulation, amplitude modulation, or a combination of frequency and amplitude modulation.
    • 在电刺激耳蜗中提供的刺激根据接收到的声信号的振幅和接收的声信号中的声音的开始进行调制以提供增加的声音感知。 在与频带相关联的声信号中检测对应于声音开始的开始时间。 确定强制电压和发射因子,其中强制电压和发射因子在检测到的起始时间与频带相关联。 声信号作为强制电压和发射因子的函数被调制以产生输出信号。 所产生的输出信号可用于刺激耳蜗。 调制策略可以与使用频率调制,幅度调制或频率和幅度调制的组合的声音处理策略结合使用。