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1. 发明授权

US08712547B2 Cavernous nerve stimulation via unidirectional propagation of action potentials 有权
标题翻译：通过动作电位的单向传播进行海绵体神经刺激
公开(公告)号：US08712547B2
公开(公告)日：2014-04-29
申请号：US13036278
申请日：2011-02-28
申请人： Todd K. Whitehurst , James P. McGivern , Rafael Carbunaru , Matthew I. Haller , Tom Xiaohai He , Kerry Bradley
发明人： Todd K. Whitehurst , James P. McGivern , Rafael Carbunaru , Matthew I. Haller , Tom Xiaohai He , Kerry Bradley
IPC分类号： A61N1/05 , A61N1/372
CPC分类号： A61N1/0556 , A61N1/0551 , A61N1/36071 , A61N1/37205
摘要： An implantable stimulation device includes a device body; at least one set of partitioned electrodes disposed on a portion of the device body and configured and arranged for application of electrical stimulation to adjacent tissue; and insulating material separating the partitioned electrodes from each other. Each set of partitioned electrodes includes a plurality of partitioned electrodes disposed around a circumference of the device body. The implantable stimulation device can be configured and arranged so that each of the partitioned electrodes is independently programmable.
摘要翻译：可植入刺激装置包括装置主体; 至少一组分隔电极，其设置在所述装置主体的一部分上，并被配置和布置成用于对相邻组织施加电刺激; 以及将分隔电极彼此分离的绝缘材料。每组分隔电极包括围绕装置主体的圆周设置的多个分隔电极。可植入式刺激装置可以被配置和布置成使得每个分隔电极可独立编程。

2. 发明授权

US08699734B1 Dual microphone EAS system that prevents feedback 失效
标题翻译：双麦克风EAS系统防止反馈
公开(公告)号：US08699734B1
公开(公告)日：2014-04-15
申请号：US13553173
申请日：2012-07-19
申请人： Matthew I. Haller
发明人： Matthew I. Haller
IPC分类号： H04R25/00
CPC分类号： H04R25/456 , A61N1/36036 , H04R25/405
摘要： An exemplary method includes an electro-acoustic stimulation (EAS) system associated with a user 1) processing sounds sensed by a first microphone coupled to a cochlear implant portion of the EAS system, 2) applying electrical stimulation representative of the sounds sensed by the first microphone by way of a plurality of electrode contacts located in a basal region of a cochlea of the user, 3) processing sounds sensed by a second microphone coupled to a hearing aid portion of the EAS system, 4) broadcasting, way of a speaker, amplified sound signals representative of the sounds sensed by the second microphone into an ear canal of the user, and 5) acoustically separating the second microphone from the speaker to avoid feedback within the hearing aid portion of the EAS system. Corresponding methods and systems are also disclosed.
摘要翻译：一种示例性方法包括与用户相关联的电声刺激（EAS）系统1）处理由耦合到EAS系统的耳蜗植入部分的第一麦克风感测到的声音; 2）施加代表由第一通过位于使用者的耳蜗的基底区域中的多个电极触点，3）处理由耦合到EAS系统的助听器部分的第二麦克风感测的声音，4）广播，扬声器的方式，放大的声音信号表示由第二麦克风感测到的声音进入用户的耳道，以及5）将声音分离第二麦克风与扬声器以避免EAS系统的助听器部分内的反馈。还公开了相应的方法和系统。

3. 发明授权

US08352046B1 Sound processing assembly for use in a cochlear implant system 有权
公开(公告)号：US08352046B1
公开(公告)日：2013-01-08
申请号：US12697028
申请日：2010-01-29
申请人： Matthew I Haller , Patrick T. Wong , Tracey Kruger , Lee F Hartley
发明人： Matthew I Haller , Patrick T. Wong , Tracey Kruger , Lee F Hartley
IPC分类号： A61N1/18
CPC分类号： A61N1/36032 , A61N1/36036 , H04R25/552 , H04R25/554 , H04R25/558
摘要： An exemplary cochlear implant system includes a sound processing assembly configured to be external to a patient and first and second extension members coupled to the sound processing assembly. The sound processing assembly includes a sound processing unit configured to process an audio signal and transmit one or more control parameters based on the audio signal to an implantable cochlear stimulator and a battery module configured to be electrically coupled to the sound processing unit and provide operating power to the sound processing unit. The first extension member has a distal portion configured to be coupled to a first ear of the patient and the second extension member has a distal portion configured to be coupled to a second ear of the patient. The first and second extension members typically extend back from the ears, thus positioning the sound processing assembly behind the patient's head.

4. 发明申请

US20110137378A1 Telemetry System for Use With Microstimulator 有权
标题翻译：用于微型激励器的遥测系统
公开(公告)号：US20110137378A1
公开(公告)日：2011-06-09
申请号：US13016246
申请日：2011-01-28
申请人： Daniel J. Klosterman , Kelly H. McClure , Goran N. Marnfeldt , Jordi Parramon , Matthew I. Haller , Rudolph V. Park
发明人： Daniel J. Klosterman , Kelly H. McClure , Goran N. Marnfeldt , Jordi Parramon , Matthew I. Haller , Rudolph V. Park
IPC分类号： A61N1/36
CPC分类号： A61N1/37276 , A61N1/36007 , A61N1/3605 , A61N1/37205 , A61N1/37217 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/3727 , A61N1/375 , A61N1/3787 , H01L2224/45144 , H01L2224/45147 , H01L2224/48465 , H01L2224/49175 , H01L2924/00011 , H01L2924/1461 , H01L2924/19105 , H01L2924/19107 , H01L2924/3011 , H01L2924/30111 , H02J7/025 , H02J7/345 , H04B5/0037 , H04B5/0081 , H04L27/02 , H04L27/10 , Y10T29/4902 , Y10T29/49071 , Y10T29/49073 , Y10T29/49128 , Y10T29/4913 , Y10T29/49155 , Y10T29/49169 , Y10T29/49826 , Y10T29/49945 , Y10T29/49968 , Y10T428/12264 , Y10T428/12271 , Y10T428/12347 , Y10T428/12375 , Y10T428/12396 , Y10T428/12535 , Y10T428/12806 , H01L2924/00 , H01L2924/01005 , H01L2924/01033
摘要： An implantable microstimulator configured to be implanted beneath a patient's skin for tissue stimulation employs a bi-directional RF telemetry link for allowing data-containing signals to be sent to and from the implantable microstimulator from at least two external devices. Further, a separate electromagnetic inductive telemetry link allows data containing signals to be sent to the implantable microstimulator from at least one of the two external devices. The RF bidirectional telemetry link allows the microstimulator to inform the patient or clinician regarding the status of the microstimulator device, including the charge level of a power source, and stimulation parameter states. The microstimulator has a cylindrical hermetically sealed case having a length no greater than about 27 mm and a diameter no greater than about 3.3 mm. A reference electrode is located on one end of the case and an active electrode is located on the other end of the case.
摘要翻译：被配置为植入在患者皮肤下方进行组织刺激的可植入微型刺激器使用双向RF遥测链路，用于允许从至少两个外部设备向可植入微型激励器发送含数据信号。此外，单独的电磁感应遥测链路允许从两个外部设备中的至少一个将包含信号的数据发送到可植入微型激励器。 RF双向遥测链路允许微刺激器通知患者或临床医生关于微刺激器装置的状态，包括电源的充电水平和刺激参数状态。微型激励器具有圆柱形密封的外壳，其长度不大于约27mm，直径不大于约3.3mm。参考电极位于壳体的一端，有源电极位于壳体的另一端。

5. 发明申请

US20110106101A1 Steerable Stylet 有权
标题翻译：方向导管
公开(公告)号：US20110106101A1
公开(公告)日：2011-05-05
申请号：US12915375
申请日：2010-10-29
申请人： Marco Tortonese , Timothy Beerling , Matthew I. Haller
发明人： Marco Tortonese , Timothy Beerling , Matthew I. Haller
IPC分类号： A61F11/00
CPC分类号： A61N1/0541 , A61M25/0102 , A61M25/0147 , A61N1/08
摘要： A stylet for inserting an electrode array into a cochlea includes a first sensor insertable within a lumen of the electrode array and sensitive to force applied by a lumen wall to the first sensor and a first actuator adapted to move the electrode array in response to the force sensed by the first sensor.
摘要翻译：用于将电极阵列插入耳蜗的探针包括可插入电极阵列的内腔内的第一传感器，并且对由第一传感器施加的管腔壁的力敏感，以及适于响应于力而移动电极阵列的第一致动器由第一传感器感测。

6. 发明授权

US07904167B2 Telemetry system for use with microstimulator 有权
标题翻译：用于微型激励器的遥测系统
公开(公告)号：US07904167B2
公开(公告)日：2011-03-08
申请号：US11624364
申请日：2007-01-18
申请人： Daniel J. Klosterman , Kelly H. McClure , Goran N. Marnfeldt , Jordi Parramon , Matthew I. Haller , Rudolph V. Park
发明人： Daniel J. Klosterman , Kelly H. McClure , Goran N. Marnfeldt , Jordi Parramon , Matthew I. Haller , Rudolph V. Park
IPC分类号： A61N1/00
CPC分类号： A61N1/37276 , A61N1/36007 , A61N1/3605 , A61N1/37205 , A61N1/37217 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/3727 , A61N1/375 , A61N1/3787 , H01L2224/45144 , H01L2224/45147 , H01L2224/48465 , H01L2224/49175 , H01L2924/00011 , H01L2924/1461 , H01L2924/19105 , H01L2924/19107 , H01L2924/3011 , H01L2924/30111 , H02J7/025 , H02J7/345 , H04B5/0037 , H04B5/0081 , H04L27/02 , H04L27/10 , Y10T29/4902 , Y10T29/49071 , Y10T29/49073 , Y10T29/49128 , Y10T29/4913 , Y10T29/49155 , Y10T29/49169 , Y10T29/49826 , Y10T29/49945 , Y10T29/49968 , Y10T428/12264 , Y10T428/12271 , Y10T428/12347 , Y10T428/12375 , Y10T428/12396 , Y10T428/12535 , Y10T428/12806 , H01L2924/00 , H01L2924/01005 , H01L2924/01033
摘要： An implantable microstimulator configured to be implanted beneath a patient's skin for tissue stimulation employs a bi-directional RF telemetry link for allowing data-containing signals to be sent to and from the implantable microstimulator from at least two external devices. Further, a separate electromagnetic inductive telemetry link allows data containing signals to be sent to the implantable microstimulator from at least one of the two external devices. The RF bidirectional telemetry link allows the microstimulator to inform the patient or clinician regarding the status of the microstimulator device, including the charge level of a power source, and stimulation parameter states. The microstimulator has a cylindrical hermetically sealed case having a length no greater than about 27 mm and a diameter no greater than about 3.3 mm. A reference electrode is located on one end of the case and an active electrode is located on the other end of the case.
摘要翻译：被配置为植入在患者皮肤下方进行组织刺激的可植入微型刺激器使用双向RF遥测链路，用于允许从至少两个外部设备向可植入微型激励器发送含数据信号。此外，单独的电磁感应遥测链路允许从两个外部设备中的至少一个将包含信号的数据发送到可植入微型激励器。 RF双向遥测链路允许微刺激器通知患者或临床医生关于微刺激器装置的状态，包括电源的充电水平和刺激参数状态。微型激励器具有圆柱形密封的外壳，其长度不大于约27mm，直径不大于约3.3mm。参考电极位于壳体的一端，有源电极位于壳体的另一端。

7. 发明申请

US20100114288A1 COCHLEAR ELECTRODE INSERTION 有权
标题翻译： COCHLEAR电极插入
公开(公告)号：US20100114288A1
公开(公告)日：2010-05-06
申请号：US12610000
申请日：2009-10-30
申请人： Matthew I. Haller , Edward H. Overstreet
发明人： Matthew I. Haller , Edward H. Overstreet
IPC分类号： A61N1/05
CPC分类号： A61B17/3468 , A61B34/30 , A61B34/76 , A61B34/77 , A61B2034/742 , A61B2090/064 , A61N1/0541 , A61N1/36036
摘要： A system for mechanically assisted insertion of an electrode includes: an insertion tool configured to insert the electrode into biological tissues; and a controller configured to control the insertion tool, in which the controller is further configured to select operating parameters comprising a maximum allowable force profile from a library of operating parameters, in which the maximum allowable force profile is generated from data recorded during a number of previous successful operations. Also, a method for insertion of a cochlear lead, includes: selecting operating parameters comprising a maximum allowable force profile from a library of operating parameters; inserting the cochlear lead while sensing real time force and position; and continuing the insertion while the real time force is below the maximum allowable force profile, in which the maximum allowable force profile is generated from data recorded during a number of previous successful operations.
摘要翻译：用于机械辅助插入电极的系统包括：插入工具，其构造成将电极插入生物组织中; 以及控制器，被配置为控制所述插入工具，其中所述控制器还被配置为从来自操作参数库的所述操作参数库中选择包括最大允许力分布的操作参数，其中由在多个以前的成功操作。另外，用于插入耳蜗导线的方法包括：从操作参数库中选择包括最大容许力分布的操作参数; 插入耳蜗线，同时感测实时力和位置; 并且当实时力低于最大允许力分布时继续插入，其中最大允许力分布由在多个先前成功操作期间记录的数据产生。

8. 发明授权

US07640061B2 Electronic module design to maximize volume efficiency 有权
标题翻译：电子模块设计，以最大限度地提高音量效率
公开(公告)号：US07640061B2
公开(公告)日：2009-12-29
申请号：US11545334
申请日：2006-10-10
申请人： Tom X. He , Matthew I. Haller , Jordi Parramon , Goran N. Marnfeldt
发明人： Tom X. He , Matthew I. Haller , Jordi Parramon , Goran N. Marnfeldt
IPC分类号： A61N1/375
CPC分类号： A61N1/37276 , A61N1/36007 , A61N1/3605 , A61N1/37205 , A61N1/37217 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/3727 , A61N1/375 , A61N1/3787 , H01L2224/45144 , H01L2224/45147 , H01L2224/48465 , H01L2224/49175 , H01L2924/00011 , H01L2924/1461 , H01L2924/19105 , H01L2924/19107 , H01L2924/3011 , H01L2924/30111 , H02J7/025 , H02J7/345 , H04B5/0037 , H04B5/0081 , H04L27/02 , H04L27/10 , Y10T29/4902 , Y10T29/49071 , Y10T29/49073 , Y10T29/49128 , Y10T29/4913 , Y10T29/49155 , Y10T29/49169 , Y10T29/49826 , Y10T29/49945 , Y10T29/49968 , Y10T428/12264 , Y10T428/12271 , Y10T428/12347 , Y10T428/12375 , Y10T428/12396 , Y10T428/12535 , Y10T428/12806 , H01L2924/00 , H01L2924/01005 , H01L2924/01033
摘要： Compact electronic modules, which may be used with implantable microstimulators and other medical and non-medical devices, and manufacture/assembly of such modules are described. Component and circuitry designs utilize unique redistribution techniques and attachment methods. A number of component designs and packaging configurations maximize the volume efficiency of electronic modules. Also included are improved processes and systems enabling the manufacture and assembly of such compact packages.
摘要翻译：描述了可与可植入微型刺激器和其他医疗和非医疗装置一起使用的紧凑型电子模块以及这种模块的制造/组装。组件和电路设计采用独特的再分配技术和附件方法。许多组件设计和封装配置使电子模块的体积效率最大化。还包括改进的工艺和系统，能够制造和组装这些紧凑型封装。

9. 发明申请

US20090281605A1 ENGAGEMENT TOOL FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：可植入医疗器械的辅助工具
公开(公告)号：US20090281605A1
公开(公告)日：2009-11-12
申请号：US12506890
申请日：2009-07-21
申请人： Goran N. Marnfeldt , Rafael Carbunaru , Kelly H. McClure , Matthew I. Haller , Tom Xiaohai He , Todd K. Whitehurst , Meredith L. Anderson , James C. Makous , Kristen N. Jaax , Peter K. Johnson
发明人： Goran N. Marnfeldt , Rafael Carbunaru , Kelly H. McClure , Matthew I. Haller , Tom Xiaohai He , Todd K. Whitehurst , Meredith L. Anderson , James C. Makous , Kristen N. Jaax , Peter K. Johnson
IPC分类号： A61N1/00
CPC分类号： A61B17/3417 , A61B17/221 , A61B17/32056 , A61B17/3468 , A61B90/30 , A61B2017/00358 , A61B2017/22035 , A61B2017/2215 , A61B2017/320044 , A61N1/05 , A61N1/08
摘要： Systems for adjusting a position of an implanted medical device within a patient include an engagement tool configured to couple to the implanted medical device. The engagement tool adjusts the position of the medical device when coupled to the implanted medical device. Methods of adjusting a position of an implanted medical device within a patient include locating the implanted medical device, coupling an engagement tool to the medical device, and adjusting a position of the engagement tool to adjust the position of the medical device.
摘要翻译：用于调整患者内植入的医疗装置的位置的系统包括被配置为耦合到植入的医疗装置的接合工具。接合工具当耦合到植入的医疗装置时调节医疗装置的位置。调整患者内的植入医疗装置的位置的方法包括定位植入的医疗装置，将接合工具联接到医疗装置，以及调整接合工具的位置以调整医疗装置的位置。

10. 发明申请

US20080208293A1 VOLTAGE CONVERTER FOR IMPLANTABLE MICROSTIMULATOR USING RF-POWERING COIL 有权
标题翻译：使用RF电源线圈的可变形微电脑电压转换器
公开(公告)号：US20080208293A1
公开(公告)日：2008-08-28
申请号：US12099474
申请日：2008-04-08
申请人： Jordi Parramon , Matthew I. Haller
发明人： Jordi Parramon , Matthew I. Haller
IPC分类号： A61N1/00 , A61N1/08
CPC分类号： A61N1/08 , A61N1/37205 , A61N1/3787
摘要： A combination, voltage converter circuit for use within an implantable device, such as a microstimulator, uses a coil, instead of capacitors, to provide a voltage step up and step down conversion functions. The output voltage is controlled, or adjusted, through duty-cycle modulation. In accordance with one aspect of the invention, applicable to implantable devices having an existing RF coil through which primary or charging power is provided, the existing RF coil is used in a time-multiplexing scheme to provide both the receipt of the RF signal and the voltage conversion function. This minimizes the number of components needed within the device, and thus allows the device to be packaged in a smaller housing or frees up additional space within an existing housing for other circuit components. In accordance with another aspect of the invention, the voltage up/down converter circuit is controlled by a pulse width modulation (PWM) low power control circuit. Such operation allows high efficiencies over a wide range of output voltages and current loads.
摘要翻译：在可植入装置（例如微型激励器）内使用的组合电压转换器电路使用线圈代替电容器来提供升压和降压转换功能。通过占空比调制来控制或调节输出电压。根据本发明的一个方面，可应用于具有通过其提供初级或充电功率的现有RF线圈的可植入装置，现有的RF线圈用于时间复用方案以提供RF信号的接收和电压转换功能。这使得器件中所需的部件的数量最小化，并因此允许将器件封装在较小的外壳中，或释放现有外壳内用于其他电路元件的额外空间。根据本发明的另一方面，电压上/下变频器电路由脉宽调制（PWM）低功率控制电路控制。这种操作允许在宽范围的输出电压和电流负载下实现高效率。

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