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21. 发明授权

US09420988B2 Systems and methods for tracking and guiding high intensity focused ultrasound beams 有权
标题翻译：用于跟踪和引导高强度聚焦超声波束的系统和方法
公开(公告)号：US09420988B2
公开(公告)日：2016-08-23
申请号：US12809617
申请日：2008-12-17
申请人： Ajay Anand , John Petruzzello
发明人： Ajay Anand , John Petruzzello
IPC分类号： A61B8/14 , A61B8/08 , A61N7/02 , A61B8/06
CPC分类号： A61B8/08 , A61B8/06 , A61B8/485 , A61B2090/378 , A61N7/02
摘要： The present disclosure provides systems and methods for tracking and guiding high intensity focused ultrasound beams (HIFU). More particularly, the disclosed systems and methods involve use of acoustic radiation force impulse (ARFI) imaging to detect the focal position of an HIFU capable transducer relative to a target area. The focal position may then be 5 compared to a desired treatment location and the orientation and focus of the transducer may be adjusted accordingly so as to reconfigure and/or refocus the HIFU beam relative to the desired treatment location. The desired treatment location may be dynamically determined using bleed detection and localization (BD&L) techniques. Thus, the desired treatment location may be determined using 3D Doppler ultrasound based techniques, wherein changes in quantitative 10 parameters extracted from the Doppler spectra, e.g., Resistance Index (RI), are used to detect and localize a bleeding site for treatment.
摘要翻译：本公开提供了用于跟踪和引导高强度聚焦超声波束（HIFU）的系统和方法。更具体地，所公开的系统和方法包括使用声辐射力脉冲（ARFI）成像来检测相对于目标区域的具有HIFU能力的传感器的焦点位置。然后可以将焦点位置与期望的治疗位置进行比较，并且相应地调节换能器的取向和焦点，以便相对于期望的治疗位置重新配置和/或重新聚焦HIFU束。可以使用出血检测和定位（BD＆L）技术动态地确定期望的治疗位置。因此，可以使用基于3D多普勒超声的技术来确定期望的治疗位置，其中使用从多普勒频谱提取的定量10个参数（例如，电阻指数（RI））的变化来检测和定位用于治疗的出血部位。

22. 发明授权

US09404734B2 System and method for sensing shape of elongated instrument 有权
标题翻译：用于感应细长仪器形状的系统和方法
公开(公告)号：US09404734B2
公开(公告)日：2016-08-02
申请号：US13603068
申请日：2012-09-04
申请人： Bhaskar S. Ramamurthy , Neal A. Tanner , Robert G. Younge , Randall L. Schlesinger
发明人： Bhaskar S. Ramamurthy , Neal A. Tanner , Robert G. Younge , Randall L. Schlesinger
IPC分类号： A61B8/00 , A61B5/06 , G01B11/16 , A61B6/12 , A61B19/00 , A61B1/00 , G01L1/24 , A61B8/08 , A61B18/08 , A61B5/00 , A61M25/01
CPC分类号： G01B11/16 , A61B1/00004 , A61B1/00013 , A61B1/00045 , A61B1/00057 , A61B1/00165 , A61B1/0017 , A61B5/0059 , A61B5/0064 , A61B5/06 , A61B5/065 , A61B5/066 , A61B5/4887 , A61B5/7285 , A61B6/12 , A61B8/00 , A61B8/48 , A61B18/082 , A61B34/20 , A61B34/30 , A61B34/37 , A61B34/71 , A61B34/77 , A61B90/39 , A61B90/96 , A61B90/98 , A61B2017/00725 , A61B2034/2061 , A61B2034/301 , A61B2034/715 , A61B2034/741 , A61B2090/374 , A61B2090/376 , A61B2090/378 , A61M2025/0166 , G01B11/165 , G01L1/242
摘要： An instrument system that includes an elongate body, an optical fiber, a localization sensor and a controller is provided. The optical fiber is operatively coupled to the elongate body and has a strain sensor provided on the optical fiber. The localization sensor is operatively coupled to the elongate body. The controller is operatively coupled to the optical fiber and to the localization sensor and is adapted to receive a first signal from the strain sensor, receive a second signal from the localization sensor, and determine a position or orientation of the elongate body based on the first signal and the second signal.
摘要翻译：提供了一种包括细长体，光纤，定位传感器和控制器的仪器系统。光纤可操作地耦合到细长主体并且具有设置在光纤上的应变传感器。定位传感器可操作地连接到细长主体。控制器可操作地耦合到光纤和定位传感器，并且适于从应变传感器接收第一信号，从定位传感器接收第二信号，并且基于第一信号确定细长体的位置或取向信号和第二信号。

23. 再颁专利

USRE46049E1 Automatic external defibrillator for the diagnosis of stroke 有权
标题翻译：自动外部除颤器用于诊断中风
公开(公告)号：USRE46049E1
公开(公告)日：2016-07-05
申请号：US13204984
申请日：2011-08-08
申请人： David Lipson , Peter Forrest
发明人： David Lipson , Peter Forrest
IPC分类号： A61B8/02 , A61B8/06 , A61B8/08 , A61B5/00 , A61B8/00 , A61B8/14 , A61B5/026 , A61B6/00 , G01S7/52 , A61N7/00 , A61B5/024
CPC分类号： A61B8/0808 , A61B5/02438 , A61B5/026 , A61B5/4076 , A61B5/6834 , A61B6/501 , A61B6/5247 , A61B8/06 , A61B8/4281 , A61B8/4416 , A61B8/481 , A61N7/00 , G01S7/52036 , G01S15/8993 , Y10S128/92
摘要： A medical diagnostic method, system and related equipment particularly adapted to diagnose disorders of the blood circulation serving the head and neck, and especially the brain. A preferred use of the system is early, rapid, accurate, diagnosis of stroke, especially whether the stroke is due to blockage of a blood vessel or leakage from the blood vessel.
摘要翻译：一种医疗诊断方法，系统和相关设备，特别适用于诊断服务于头颈部的血液循环障碍，特别是脑部。系统的优选使用是早期，快速，准确的，中风的诊断，特别是中风是由于血管的阻塞还是来自血管的泄漏。

24. 发明授权

US09367904B2 Spatial-temporal warping of different pre-captured medical images 有权
标题翻译：不同的预先拍摄的医学图像的空间扭曲
公开(公告)号：US09367904B2
公开(公告)日：2016-06-14
申请号：US12596847
申请日：2008-04-18
申请人： Jurgen Weese , Jorg Bredno
发明人： Jurgen Weese , Jorg Bredno
IPC分类号： G06Q50/22 , G06T5/50 , A61B6/00 , G06Q50/24
CPC分类号： G06T5/50 , A61B6/481 , A61B6/504 , G06T2207/10116 , G06T2207/30048 , G06T2207/30101
摘要： It is described a method for medical image comparison purposes, comprising the step of generating a first global image or mask with increased similarity to a second global image, wherein the first global image comprises at least partially a composition of different pre-captured images of a patient; wherein the pre-captured images are captured at different times.
摘要翻译：描述了一种用于医学图像比较目的的方法，包括以下步骤：产生具有增加的与第二全局图像的相似性的第一全局图像或掩模，其中第一全局图像至少部分地包括不同的预捕获图像的组合患者; 其中在不同时间捕获预先捕获的图像。

25. 发明授权

US09186047B2 Instrument systems and methods utilizing optical fiber sensor 有权
标题翻译：利用光纤传感器的仪器系统和方法
公开(公告)号：US09186047B2
公开(公告)日：2015-11-17
申请号：US13602853
申请日：2012-09-04
申请人： Bhaskar S. Ramamurthy , Neal A. Tanner , Robert G. Younge , Randall L. Schlesinger
发明人： Bhaskar S. Ramamurthy , Neal A. Tanner , Robert G. Younge , Randall L. Schlesinger
IPC分类号： A61B1/01 , A61B1/04 , A61B1/00 , A61B5/06 , A61B6/12 , A61B19/00 , G01B11/16 , G01L1/24 , A61B8/08 , A61B18/08 , A61B8/00 , A61B5/00
CPC分类号： G01B11/16 , A61B1/00004 , A61B1/00013 , A61B1/00045 , A61B1/00057 , A61B1/00165 , A61B1/0017 , A61B5/0059 , A61B5/0064 , A61B5/06 , A61B5/065 , A61B5/066 , A61B5/4887 , A61B5/7285 , A61B6/12 , A61B8/00 , A61B8/48 , A61B18/082 , A61B34/20 , A61B34/30 , A61B34/37 , A61B34/71 , A61B34/77 , A61B90/39 , A61B90/96 , A61B90/98 , A61B2017/00725 , A61B2034/2061 , A61B2034/301 , A61B2034/715 , A61B2034/741 , A61B2090/374 , A61B2090/376 , A61B2090/378 , A61M2025/0166 , G01B11/165 , G01L1/242
摘要： An instrument system that includes an elongate instrument body and an optical fiber sensor is provided. The optical fiber sensor includes an elongate optical fiber that is coupled to the elongate instrument body, wherein a portion of the optical fiber is coupled to the elongate instrument body in a manner to provide slack in the fiber to allow for axial extension of the elongate instrument body relative to the optical fiber.
摘要翻译：提供了一种包括细长仪器主体和光纤传感器的仪器系统。光纤传感器包括细长的光纤，其连接到细长的器械主体，其中光纤的一部分以一种在光纤中提供松弛以允许细长仪器的轴向延伸的方式联接到细长器械本体身体相对于光纤。

26. 发明授权

US08957439B2 LED assembly 有权
标题翻译： LED组装
公开(公告)号：US08957439B2
公开(公告)日：2015-02-17
申请号：US13131384
申请日：2009-11-27
申请人： Hans-Helmut Bechtel , Matthias Heidemann , Peter J. Schmidt , Thomas Diederich
发明人： Hans-Helmut Bechtel , Matthias Heidemann , Peter J. Schmidt , Thomas Diederich
IPC分类号： H01L33/00 , H01L33/50 , H01L33/46
CPC分类号： H01L33/50 , H01L24/32 , H01L33/46 , H01L33/58 , H01L33/60 , H01L2924/12041 , H01L2924/00
摘要： A light emission diode (LED) assembly, comprising a LED die (10), a phosphor layer (12), and a filter layer (14), wherein said filter layer (14) is developed in such a manner that light rays with a wavelength of about 400 nm to 500 nm, preferably of about 420 nm to 490 nm, emitted from the LED die (10) are at least partially reflected depending on their emission angle to the normal on the filter layer (14). With the inventive LED assembly it is possible to provide a LED assembly which solves the yellow ring problem without a reduction of the efficiency of the LED assembly.
摘要翻译：一种发光二极管（LED）组件，包括LED管芯（10），荧光体层（12）和过滤层（14），其中所述过滤层（14）以如下方式显影：从LED管芯（10）发射的约400nm至500nm，优选约420nm至490nm的波长至少部分地根据其与滤光层（14）上的法线的发射角部分反射。利用本发明的LED组件，可以提供一种在不降低LED组件的效率的情况下解决黄色环问题的LED组件。

27. 发明申请

US20140375975A1 Stage System and a Lithographic Apparatus 有权
标题翻译：舞台系统和平版印刷设备
公开(公告)号：US20140375975A1
公开(公告)日：2014-12-25
申请号：US14376210
申请日：2013-01-25
申请人： ASML Netherlands B.V. , Koninklijke Philips Electronics N.V. `
发明人： Bastiaan Lambertus Wilhelmus Marinus Van De Ven , Antonius Franciscus Johannes De Groot , Johannes Petrus Martinus Bernardus Vermeulen , Theodorus Petrus Maria Cadee , Robertus Mathijs Gerardus Rijs , Richard Henricus Adrianus Van Lieshout
IPC分类号： G03F7/20 , H02K41/02
CPC分类号： G03F7/70716 , G03F7/70758 , G03F7/709 , H02K41/02
摘要： A movable stage system is configured to support an object subjected to a lithography process. A short stroke part (SS) is configured to support the object (W) and a long stroke part (LS) is configured to support the short stroke part. The short stroke part is movable over a relative small range of movement with respect to the long stroke part. The long stroke part is movable over a relative large range of movement with respect to a base support arranged to support the long stroke part. A shielding element (SE) is arranged between the short and long stroke parts. A position control system (PCS) maintains a substantially constant distance between the shielding element and the short stroke part.
摘要翻译：可移动台系统被配置为支撑经受光刻处理的物体。短行程部件（SS）被配置为支撑物体（W），并且长行程部件（LS）被配置为支撑短行程部件。短行程部分可以相对于长行程部分在相对较小的移动范围内移动。长行程部件可相对于布置成支撑长行程部件的基座支撑件在相对较大的运动范围内移动。屏蔽元件（SE）设置在短行程部件和长行程部件之间。位置控制系统（PCS）在屏蔽元件和短行程部件之间保持基本恒定的距离。

28. 发明授权

US08907364B2 LED package comprising encapsulation 有权
标题翻译： LED封装包括封装
公开(公告)号：US08907364B2
公开(公告)日：2014-12-09
申请号：US13993733
申请日：2011-12-29
申请人： Serge Joel Armand Bierhuizen
发明人： Serge Joel Armand Bierhuizen
IPC分类号： H01L33/60 , H01L33/52 , H01L33/48 , H01L33/50 , H01L25/075
CPC分类号： H01L33/52 , H01L25/0753 , H01L33/486 , H01L33/50 , H01L33/60 , H01L2224/16225 , H01L2224/48091 , H01L2224/48247 , H01L2924/00014
摘要： Light emitting elements (110) are situated on a film (210), then surrounded by a reflective structure (250) that is placed or formed on the film (210). Thereafter, the reflective structure (250) is filled with an encapsulant (270), affixing the light emitting element (110) within the reflective structure (250). The film (210) may then be removed, exposing the contacts (230) for coupling the light emitting element (110) to an external power source. The encapsulated light emitting elements (110) within the reflective structure (250) are diced/singulated to provide the individual light emitting devices. The encapsulant (270) may be molded or otherwise shaped to provide a desired optical function.
摘要翻译：发光元件（110）位于膜（210）上，然后被放置或形成在膜（210）上的反射结构（250）包围。此后，反射结构（250）填充有将发光元件（110）固定在反射结构（250）内的密封剂（270）。然后可以去除胶片（210），暴露用于将发光元件（110）耦合到外部电源的触点（230）。反射结构（250）内的封装发光元件（110）被切割/切片以提供各个发光器件。密封剂（270）可以被模制或以其他方式成形以提供期望的光学功能。

29. 发明授权

US08864655B2 Fiber optic instrument shape sensing system and method 有权
标题翻译：光纤仪表形状检测系统及方法
公开(公告)号：US08864655B2
公开(公告)日：2014-10-21
申请号：US13603135
申请日：2012-09-04
申请人： Bhaskar S. Ramamurthy , Neal A. Tanner , Robert G. Younge , Randall L. Schlesinger , Eric Udd
发明人： Bhaskar S. Ramamurthy , Neal A. Tanner , Robert G. Younge , Randall L. Schlesinger , Eric Udd
IPC分类号： A61B1/01 , A61B1/04 , A61B1/00 , A61B5/00 , A61B18/08 , A61B8/00 , A61B5/06 , A61B6/12 , G01B11/16 , G01L1/24 , A61B8/08 , A61B19/00
CPC分类号： G01B11/16 , A61B1/00004 , A61B1/00013 , A61B1/00045 , A61B1/00057 , A61B1/00165 , A61B1/0017 , A61B5/0059 , A61B5/0064 , A61B5/06 , A61B5/065 , A61B5/066 , A61B5/4887 , A61B5/7285 , A61B6/12 , A61B8/00 , A61B8/48 , A61B18/082 , A61B34/20 , A61B34/30 , A61B34/37 , A61B34/71 , A61B34/77 , A61B90/39 , A61B90/96 , A61B90/98 , A61B2017/00725 , A61B2034/2061 , A61B2034/301 , A61B2034/715 , A61B2034/741 , A61B2090/374 , A61B2090/376 , A61B2090/378 , A61M2025/0166 , G01B11/165 , G01L1/242
摘要： An instrument system that includes an elongate body, an optical fiber, and a controller is provided. The optical fiber is operatively coupled to the elongate body and has a plurality of strain sensors provided on the optical fiber. Each of the plurality of strain sensors has a reflectivity, wherein one of the plurality of strain sensors has a different reflectivity than another one of the plurality of strain sensors. The controller is operatively coupled to the optical fiber and adapted to: receive one or more signals from the plurality of strain sensors; and determine a position of the elongate body based on the one or more signals.
摘要翻译：提供一种包括细长体，光纤和控制器的仪器系统。光纤可操作地耦合到细长主体并且具有设置在光纤上的多个应变传感器。多个应变传感器中的每一个具有反射率，其中多个应变传感器中的一个具有与多个应变传感器中的另一个不同的反射率。控制器可操作地耦合到光纤并且适于：从多个应变传感器接收一个或多个信号; 并且基于所述一个或多个信号确定所述细长体的位置。

30. 发明授权

US08818143B2 Optical fiber instrument system for detecting twist of elongated instruments 有权
标题翻译：用于检测细长仪器扭转的光纤仪器系统
公开(公告)号：US08818143B2
公开(公告)日：2014-08-26
申请号：US13594646
申请日：2012-08-24
申请人： Robert G. Younge , Bhaskar S. Ramamurthy , Neal A. Tanner , Randall L. Schlesinger , Eric Udd
发明人： Robert G. Younge , Bhaskar S. Ramamurthy , Neal A. Tanner , Randall L. Schlesinger , Eric Udd
IPC分类号： G02B6/00 , A61B1/07
CPC分类号： G02B6/022 , A61B5/1076 , A61B5/6852 , A61B2017/00039 , A61B2017/00053 , A61B2034/2061 , A61B2090/067
摘要： An instrument system that includes an elongate body and an optical fiber is provided. The elongate body has a longitudinal axis and capable of being twisted about the longitudinal axis. The optical fiber is operatively coupled with the elongate body and having a strain sensor provided thereon. The strain sensor is configured to indicate twist of the elongate body.
摘要翻译：提供了一种包括细长体和光纤的仪器系统。细长主体具有纵向轴线并且能够围绕纵向轴线扭曲。光纤与细长主体可操作地耦合并且具有设置在其上的应变传感器。应变传感器构造成指示细长体的扭转。

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