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    • 22. 发明授权
    • Systems and methods for seeking sub-surface temperature conditions
during tissue ablation
    • 在组织消融期间寻求次表面温度条件的系统和方法
    • US6030379A
    • 2000-02-29
    • US935281
    • 1997-09-22
    • Dorin PanescuThomas M. Bourne
    • Dorin PanescuThomas M. Bourne
    • A61B17/00A61B18/00A61B18/12A61B18/14A61N1/40
    • A61B18/1492A61N1/403A61B18/1206A61B2017/00084A61B2017/00243A61B2018/00023A61B2018/00029A61B2018/0069A61B2018/126A61B2018/1861
    • Systems and methods for ablating body tissue use an ablation element for contacting tissue to form a tissue interface. The ablation element is adapted to be connected to a source of ablation energy to conduct ablation energy for transmission by the ablation element into tissue at the tissue interface. The systems and methods include a tissue temperature sensing element held in a carrier in thermal conductive contact with tissue beneath the tissue interface. A mechanism attached to the carrier selectively advances the carrier relative to the ablation element to different depths beneath the tissue interface. A controller is coupled to the mechanism and to the tissue temperature sensing element to control advancement of the carrier beneath the tissue interface based, at least in part, upon tissue temperatures sensed by the sensing element beneath the tissue interface. Preferably, the controller controls the mechanism to locate the sensing element at the depth where the hottest sensed tissue temperature exists.
    • 用于消融身体组织的系统和方法使用消融元件来接触组织以形成组织界面。 消融元件适于连接到消融能量源,以传导消融能量,以将消融元件传导到组织界面处的组织中。 该系统和方法包括保持在载体中的组织温度感测元件,与组织界面下方的组织进行导热接触。 连接到载体的机构选择性地将载体相对于消融元件前进到组织界面下方的不同深度。 至少部分地,控制器耦合到机构和组织温度感测元件,以至少部分地基于由组织界面下方的感测元件感测的组织温度来控制组织界面下方的载体的前进。 优选地,控制器控制将感测元件定位在存在最热感测的组织温度的深度处的机构。
    • 24. 发明授权
    • Systems and methods employing structures having asymmetric mechanical
properties to support diagnostic or therapeutic elements in contact
with tissue in interior body regions
    • 使用具有不对称机械性能的结构以支持与内部身体区域中的组织接触的诊断或治疗元件的系统和方法
    • US6014590A
    • 2000-01-11
    • US742564
    • 1996-10-28
    • James G. WhayneSidney D. FleischmanDorin PanescuThomas F. KordisDavid K. Swanson
    • James G. WhayneSidney D. FleischmanDorin PanescuThomas F. KordisDavid K. Swanson
    • A61B17/39
    • Structures having asymmetric mechanical properties provide enhanced ability to support therapeutic or diagnostic elements in contact with tissue in an interior body region. The support structure includes a first region, which exhibits a first mechanical property affecting tissue contact, and a second region spaced from the first region about the axis, which exhibits a second mechanical property, different than the first mechanical property, affecting tissue contact. In a preferred embodiment, the first and second mechanical properties correlate with stiffness of the respective first and second regions, with the first region being more flexible (i.e., less stiff) than the second region. The first region, due to its greater flexibility, is more conformal to tissue than the second region. The less flexible (i.e., more stiff) second region imparts greater force against the tissue to urge the more flexible first region toward intimate tissue contact. In a preferred embodiment, the more flexible first region carries at least one therapeutic or diagnostic element.
    • 具有不对称机械特性的结构提供增强的能力,以支持与内部身体区域中的组织接触的治疗或诊断元件。 支撑结构包括表现出影响组织接触的第一机械特性的第一区域以及围绕轴线与第一区域隔开的第二区域,该第二区域具有影响组织接触的第二机械特性,该第二机械特性不同于第一机械特性。 在优选实施例中,第一和第二机械特性与相应的第一和第二区域的刚度相关,其中第一区域比第二区域更加柔性(即,较不硬)。 第一个区域由于其更大的灵活性,比第二个区域更适合组织。 较不柔性(即更硬)的第二区域赋予组织更大的力以促使更柔性的第一区域朝向紧密的组织接触。 在优选实施方案中,更灵活的第一区域携带至少一种治疗或诊断元件。