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21. 发明申请

US20120194438A1 ELECTRONIC READER WITH CHINESE PINYIN INPUT FUNCTION AND CHINESE PINYIN INPUT METHOD 审中-公开
标题翻译：具有中文PINYIN输入功能和中文PINYIN输入法的电子阅读器
公开(公告)号：US20120194438A1
公开(公告)日：2012-08-02
申请号：US13187518
申请日：2011-07-21
申请人： WEI SONG , HUI-LING HUANG
发明人： WEI SONG , HUI-LING HUANG
IPC分类号： G06F3/02
CPC分类号： G06F3/018 , G06F3/04886
摘要： An electronic reader includes a touch display screen receiving user inputs and displaying a keypad and a processing unit. The keypad includes a plurality of first keys and a plurality of second keys, the keypad selectively operable between a pinyin mode where the first keys display letters a to z, and a Chinese character mode where the first keys display Chinese characters. The processing unit controls the electronic reader to enter the Pinyin mode, displays an intended pinyin inputted by a user on one of the second keys, activates the keypad to enter into the Chinese character mode whereby according to the input of the pinyin and displays a plurality of possible Chinese characters on the first keys, selects and displays a intended Chinese character in an entry field. A Chinese pinyin input method is also provided.
摘要翻译：电子阅读器包括接收用户输入并显示小键盘和处理单元的触摸显示屏。键盘包括多个第一键和多个第二键，键盘可选择性地在第一键显示字母a到z的拼音模式和第一键显示汉字的汉字模式之间操作。处理单元控制电子阅读器进入拼音模式，在第二个键之一上显示由用户输入的预期拼音，激活键盘进入汉字模式，借此根据拼音的输入并显示多个在第一个键上可能的汉字，在输入字段中选择并显示预期的汉字。还提供了中文拼音输入法。

22. 发明申请

US20120166943A1 ELECTRONIC DEVICE HAVING PAGE DIVISION DISPLAY FUNCTION AND PAGE DISPLAY METHOD 审中-公开
标题翻译：具有页面分割显示功能的电子设备和页面显示方法
公开(公告)号：US20120166943A1
公开(公告)日：2012-06-28
申请号：US13118474
申请日：2011-05-30
申请人： HUI-LING HUANG , XIAO-GUANG LI , HONG-YE LIU , XIAO-LE LI
发明人： HUI-LING HUANG , XIAO-GUANG LI , HONG-YE LIU , XIAO-LE LI
IPC分类号： G06F17/00
CPC分类号： G06F3/0483 , G06F3/04892
摘要： An electronic device which comprises a storage unit to store files and a division information table, an input unit generating input signals in response to user input operations, a display unit displaying information, and a processing unit controlling the electronic device to enter into a reading mode, controlling the display unit to a page of a file, determining whether the page has a portrait layout or a horizontal layout according to the properties of the page, dividing the page into a plurality of blocks according to a division information table, controlling the display unit to display all the blocks thereon, and displaying a selected block of the page with a magnified display size according to an input signal from the user. A page display method is also provided.
摘要翻译：一种电子设备，包括存储文件和分割信息表的存储单元，响应于用户输入操作产生输入信号的输入单元，显示信息的显示单元和控制电子设备进入读取模式的处理单元，将显示单元控制到文件的页面，根据页面的属性确定页面是否具有纵向布局或水平布局，根据分割信息表将页面分割成多个块，控制显示单元，用于显示其上的所有块，并且根据来自用户的输入信号，以放大的显示尺寸显示页面的选定块。还提供了页面显示方法。

23. 发明申请

US20120164396A1 MATRIX ASSISTED INK TRANSPORT 审中-公开
标题翻译： MATRIX辅助墨水运输
公开(公告)号：US20120164396A1
公开(公告)日：2012-06-28
申请号：US12140780
申请日：2008-06-17
申请人： Chad A. Mirkin , Ling Huang , Fengwei Huo , Sarah J. Hurst , Lidong Qin , Jae-Won Jang , Joseph J. Kakkassery
发明人： Chad A. Mirkin , Ling Huang , Fengwei Huo , Sarah J. Hurst , Lidong Qin , Jae-Won Jang , Joseph J. Kakkassery
IPC分类号： B05D5/00 , B32B3/10 , B82Y40/00
CPC分类号： C09D11/03 , B01J19/0046 , B01J2219/00382 , B01J2219/00387 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00648 , B01J2219/00653 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , B01J2219/00731 , B01J2219/00734 , B82Y30/00 , C09D11/30 , C40B50/14 , Y10T428/24802 , Y10T436/143333 , Y10T436/25 , Y10T436/2575
摘要： Provided is a direct write patterning method utilizing a mixture comprising an ink of choice and an ink carrier matrix. The method involves disposing the mixture on a tip or stamp and transporting the mixture from the tip or stamp on a surface to form a pattern that contains the ink. The method does not require chemical or physical modification of either the tip or stamp or the surface prior to transporting the mixture to the surface. The method can be applied for patterning hard inks such as nanomaterials and crystallized polymers and soft inks such as biomaterials including peptides and proteins. Also provided are related biomaterial and hard ink arrays.
摘要翻译：提供了一种使用包括选择的墨水和墨水载体基质的混合物的直接写入图案化方法。该方法包括将混合物设置在尖端或印模上，并将混合物从尖端或印模输送到表面上以形成包含油墨的图案。在将混合物输送到表面之前，该方法不需要对尖端或印模或表面进行化学或物理改性。该方法可以应用于诸如纳米材料和结晶聚合物的硬油墨和软油墨如包括肽和蛋白质的生物材料的图形化。还提供了相关的生物材料和硬油墨阵列。

24. 发明申请

US20120141476A1 FcGammaRIIB Specific Antibodies and Methods of Use Thereof 有权
标题翻译： FcGammaRIIB特异性抗体及其使用方法
公开(公告)号：US20120141476A1
公开(公告)日：2012-06-07
申请号：US13367626
申请日：2012-02-07
申请人： Leslie S. Johnson , Ling Huang
发明人： Leslie S. Johnson , Ling Huang
IPC分类号： A61K39/395 , A61N5/00 , A61P35/00
CPC分类号： C07K16/283 , A61K2039/505 , C07K2317/24 , C07K2317/34
摘要： The present invention relates to antibodies or fragments thereof that bind FcγRIIB with greater affinity than said antibodies or fragments binds FcγRIIA. The invention encompasses the use of such antibodies or fragments for the treatment of diseases related to loss of balance of Fc receptor mediated signaling, such as cancer, autoimmune diseases, inflammatory diseases or IgE-mediated allergic disorders. The present invention also encompasses the use of such antibodies and fragments in combination with other cancer therapies, methods of enhancing the therapeutic effect of therapeutic antibodies, and methods of enhancing efficacy of vaccine compositions.
摘要翻译：本发明涉及以比所述抗体或片段更高的亲和力结合FcγRIIA的FcγRIIA结合FcγRIIA的抗体或其片段。本发明包括这样的抗体或片段用于治疗与Fc受体介导的信号传导的平衡丧失有关的疾病，例如癌症，自身免疫性疾病，炎性疾病或IgE介导的过敏性疾病的用途。本发明还包括这样的抗体和片段与其它癌症治疗组合的用途，增强治疗性抗体治疗效果的方法，以及增强疫苗组合物功效的方法。

25. 外观设计

USD651883S1 Holder for hand tools 有权
标题翻译：手持工具支架
公开(公告)号：USD651883S1
公开(公告)日：2012-01-10
申请号：US29370802
申请日：2010-09-07
申请人： Chia-Ling Huang
设计人： Chia-Ling Huang

26. 发明申请

US20110274347A1 METHOD OF DETECTING RED EYE IMAGE AND APPARATUS THEREOF 有权
标题翻译：检测红眼图像的方法及其设备
公开(公告)号：US20110274347A1
公开(公告)日：2011-11-10
申请号：US12886572
申请日：2010-09-21
申请人： Ting-Yuan Cheng , Pai-Yu Tien , Sheng-Ling Huang
发明人： Ting-Yuan Cheng , Pai-Yu Tien , Sheng-Ling Huang
IPC分类号： G06T7/00
CPC分类号： G06T7/90 , G06T7/12 , G06T2207/30216
摘要： A redeye image detection method for detecting at least one redeye image in an input image includes: deriving an edge detection result by performing an edge detection process to detect an edge characteristic of the input image; deriving a red pixel detection result by performing a red pixel detection process to detect red pixels in the input image, and utilizing a determining circuit to derive a preliminary detection result according to the edge detection result and the red pixel detection result, and derive the redeye image according to the preliminary detection result.
摘要翻译：用于检测输入图像中的至少一个红眼图像的红眼图像检测方法包括：通过执行边缘检测处理来检测输入图像的边缘特征来导出边缘检测结果; 通过执行红色像素检测处理来检测输入图像中的红色像素，并且利用确定电路根据边缘检测结果和红色像素检测结果导出初步检测结果，得到红色像素检测结果，并导出红眼图像根据初步检测结果。

27. 发明授权

US07972837B2 Signal enhancement system with multiple labeled-moieties 有权
标题翻译：具有多个标记部分的信号增强系统
公开(公告)号：US07972837B2
公开(公告)日：2011-07-05
申请号：US12042762
申请日：2008-03-05
申请人： Helen Lee , Ling Huang , Magda Anastassova Dineva , Hsiang Yun Hu
发明人： Helen Lee , Ling Huang , Magda Anastassova Dineva , Hsiang Yun Hu
IPC分类号： G01N33/53
CPC分类号： G01N33/558 , Y10S435/81 , Y10S436/807 , Y10S977/70 , Y10S977/773 , Y10S977/788 , Y10S977/918
摘要： Dipstick tests for detecting analyte are described. In a preferred embodiment, a multiple biotinylated antibody capable of binding analyte is bound to an anti-biotin antibody labeled with colloidal gold and wicked up the dipstick with test solution thought to contain analyte. Complex formed between analyte, biotinylated anti-analyte antibody, and colloidal gold labeled anti-biotin antibody is captured at a capture zone of the dipstick. Presence of colloidal gold label at the capture zone indicates the presence of analyte in the test solution. The sensitivity of analyte detection using such methods is an order of magnitude higher than for comparable methods in which biotinylated anti-analyte antibody bound to analyte is wicked up the dipstick in a first step, and a colloidal gold labeled anti-biotin antibody is wicked up the dipstick in a separate step. Kits for performing the tests of the invention are also described.
摘要翻译：描述了用于检测分析物的浸渍试验。在优选的实施方案中，能够结合分析物的多重生物素化抗体与由胶体金标记的抗生物素抗体结合，并且将被认为含有分析物的测试溶液弄脏。分析物，生物素化抗分析物抗体和胶体金标记的抗生物素抗体之间形成的复合物在量油尺的捕获区捕获。在捕获区存在胶体金标记表示测试溶液中存在分析物。使用这种方法的分析物检测的灵敏度比在第一步中将测得的与分析物结合的生物素化的抗分析物抗体被弄脏的可比较方法高一个数量级，并且胶体金标记的抗生物素抗体被恶化量油尺在一个单独的步骤。还描述了用于执行本发明的测试的套件。

28. 发明申请

US20110097323A1 Her2/neu-Specific Antibodies and Methods of Using Same 有权
标题翻译： Her2 / neu特异性抗体及其使用方法
公开(公告)号：US20110097323A1
公开(公告)日：2011-04-28
申请号：US12933885
申请日：2009-03-25
申请人： Leslie S. Johnson , Ling Huang , Nadine Tuaillon , Ezio Bonvini
发明人： Leslie S. Johnson , Ling Huang , Nadine Tuaillon , Ezio Bonvini
IPC分类号： A61K39/395 , C07K16/28 , A61P35/04
CPC分类号： C07K16/32 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/54 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/71 , C07K2317/732 , C07K2317/92
摘要： This invention relates to antibodies that specifically bind HER2/neu, and particularly chimeric 4D5 antibodies to HER2/neu, which have reduced glycosylation as compared to known 4D5 antibodies. The invention also relates to methods of using the 4D5 antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious disease.
摘要翻译：本发明涉及与已知的4D5抗体相比具有降低的糖基化的HER2 / neu特异性结合HER2 / neu的嵌合4D5抗体的抗体。本发明还涉及将4D5抗体及其组合物用于诊断，预后和治疗疾病如癌症，自身免疫性疾病，炎症性疾病和感染性疾病的方法。

29. 发明申请

US20110094977A1 SUPPORTING RACK WITH ADJUSTABLE TORSION 审中-公开
标题翻译：支持可调节扭矩的机架
公开(公告)号：US20110094977A1
公开(公告)日：2011-04-28
申请号：US12693479
申请日：2010-01-26
申请人： Chin-Chen Li , Shih-Ling Huang
发明人： Chin-Chen Li , Shih-Ling Huang
IPC分类号： A47F7/00
CPC分类号： F16M11/14 , F16C11/106 , F16M2200/022
摘要： A supporting rack for supporting an electronic device includes a main body, a rotating arm, a fastening member and a position portion. The main body includes a connecting portion and a plurality of holding members. The connecting portion is connected with the electronic device, the holding members are disposed on the connecting portion, and each of which includes a first surface and a second surface opposite thereto. A gap is formed between adjacent holding members. The rotating arm, held by the holding members, tightly contacts the first surface. The fastening member connects with the holding members between a first position and a second position. The position portion is disposed on the holding member. When the fastening member is connected with the holding members at the first position, an interference, formed between the fastening members and the second surface, is increased as the fastening member is moved toward the second position.
摘要翻译：用于支撑电子装置的支撑架包括主体，旋转臂，紧固构件和位置部分。主体包括连接部分和多个保持部件。连接部分与电子装置连接，保持构件设置在连接部分上，并且每个包括第一表面和与其相对的第二表面。在相邻的保持构件之间形成间隙。由保持构件保持的旋转臂与第一表面紧密接触。紧固构件在第一位置和第二位置之间与保持构件连接。位置部分设置在保持构件上。当紧固构件与第一位置处的保持构件连接时，随着紧固构件向第二位置移动，形成在紧固构件和第二表面之间的干涉增加。

30. 发明授权

US07906327B2 Dual expression vector system for antibody expression in bacterial and mammalian cells 有权
标题翻译：用于细菌和哺乳动物细胞中抗体表达的双重表达载体系统
公开(公告)号：US07906327B2
公开(公告)日：2011-03-15
申请号：US11503399
申请日：2006-08-10
申请人： Leslie Sydnor Johnson , Ling Huang
发明人： Leslie Sydnor Johnson , Ling Huang
IPC分类号： C12N15/00 , C12N1/21 , C12N5/07
CPC分类号： C07K16/00 , A01K2267/01 , C07K16/283 , C07K2317/10 , C07K2317/24 , C07K2317/51 , C07K2317/52 , C07K2317/55 , C07K2317/622 , C07K2319/30 , C12N7/00 , C12N15/8509 , C12N2795/14043
摘要： The present invention provides a dual expression vector, and methods for its use, for the expression and secretion of a full-length polypeptide of interest in eukaryotic cells, and a soluble domain or fragment of the polypeptide in bacteria. When expressed in bacteria, transcription from a bacterial promoter within a first intron and termination at the stop codon in a second intron results in expression of a fragment of the polypeptide, e.g., a Fab fragment, whereas in mammalian cells, splicing removes the bacterial regulatory sequences located in the two introns and generates the mammalian signal sequence, allowing expression of the full-length polypeptide, e.g., IgG heavy or light chain polypeptide. The dual expression vector system of the invention can be used to select and screen for new monoclonal antibodies, as well as to optimize monoclonal antibodies for binding to antigenic molecules of interest.
摘要翻译：本发明提供双重表达载体及其用于在真核细胞中表达和分泌全长多肽的方法，以及细菌中多肽的可溶性结构域或片段。当在细菌中表达时，来自第一内含子内的细菌启动子的转录和终止密码子在第二内含子中终止导致多肽片段的表达，例如Fab片段，而在哺乳动物细胞中，剪接除去细菌调节位于两个内含子中的序列并产生哺乳动物信号序列，允许表达全长多肽，例如IgG重链或轻链多肽。本发明的双表达载体系统可用于选择和筛选新的单克隆抗体，以及优化用于结合感兴趣的抗原分子的单克隆抗体。

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