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    • 22. 发明授权
    • Hemodynamically responsive system for and method of treating a
malfunctioning heart
    • 血液动力学反应系统和治疗失败的心脏的方法
    • US4984572A
    • 1991-01-15
    • US385544
    • 1989-07-27
    • Todd J. Cohen
    • Todd J. Cohen
    • A61N1/365A61N1/39
    • A61N1/3918A61N1/36564A61N1/3962
    • A system for and method of treating a malfunctioning heart is based on hemodynamics, the pressure at a site in a patient's circulatory system being sensed. A signal is developed representative of short term mean arterial pressure (MAP), mean right atrial pressure (MRAP), mean right ventricle pressure (MRVP), mean left atrial pressure (MLAP), mean left ventricle pressure (MLVP), mean central venous pressure (MCVP), mean pulmonary artery pressure (MPAP), mean pulmonary vein pressure (MPVP), mean pulmonary capillary wedge pressure (MPCWP), right ventricular systolic pressure (RVSP), right ventricular end diastolic pressure (RVEDP), or right ventricular pulse presure (RVPP). A signal representative of fixed or varying baseline pressure is provided and if the short term current pressure differs therefrom by a predetermined value, an indication of hemodynamic compromise, cardioversion/defibrillation is effected. In a second embodiment, the determination of whether the difference between fixed or varying baseline pressure and current pressure is undertaken after a rate criteria (for example a heart rate above 155 b.p.m.) has been met. In a third embodiment, the rate and pressure criteria both must exist at the same time, before cardioverting/-defibrillation is initiated. In a fourth embodiment, a microprocessor is used. The system may be integrated with antitachycardia and/or antibradycardia pacemakers.
    • 用于治疗故障心脏的系统和方法基于血液动力学,被感测的患者循环系统中的部位处的压力。 代表短期平均动脉压(MAP),平均右心房压(MRAP),平均右心室压(MRVP),平均左心房压(MLAP),平均左心室压(MLVP),平均中心静脉 平均肺动脉压(MPVP),平均肺静脉压(MPVP),平均肺毛细血管楔压(MPCWP),右心室收缩压(RVSP),右心室舒张压(RVEDP)或右心室 脉冲压力(RVPP)。 提供代表固定或变化的基线压力的信号,并且如果短期电流压力与预定值不同,则进行血液动力学妥协的指示,进行心脏复律/除颤。 在第二实施例中,确定在基准压力和当前压力之间的差异是否已经满足速率标准(例如高于155b.p.m.的心率)之后进行。 在第三实施例中,速率和压力标准两者都必须同时存在,在开始心脏转复/ - 除颤之前。 在第四实施例中,使用微处理器。 该系统可以与抗心动过速和/或抗心动过缓起搏器整合。
    • 23. 发明授权
    • Hemodynamically responsive system for and method of treating a
malfunctioning heart
    • 血液动力学反应系统和治疗失败的心脏的方法
    • US4774950A
    • 1988-10-04
    • US105030
    • 1987-10-06
    • Todd J. Cohen
    • Todd J. Cohen
    • A61N1/365A61N1/39A61N1/00
    • A61N1/36564A61N1/3918A61N1/3962
    • A system for and method of treating a malfunctioning heart is based on hemodynamics. The mean arterial pressure (MAP) mean right atrial pressure (MRAP), mean right ventrical pressure (MRVP), mean left atrial pressure (MLAP), mean left ventrical pressure (MLVP) or mean central venous pressure (MCVP) is sensed. The long term mean baseline pressure is monitored and if the short term current mean pressure differs therefrom by a predetermined value, an indication of hemodynamic compromise, cardioversion/defibrillation is effected. In a second embodiment, the determination of whether the difference between mean baseline and mean current pressure is undertaken after a rate criteria (for example a heart rate above 155 b.p.m. has been met. In a third embodiment, the rate and pressure criteria both must exist at the same time, before cardioverting/defibrillation is initiated. In a fourth embodiment, a microprocessor is used. The system may be integrated with antitachycardia and/or antibradycardia pacemakers.
    • 治疗故障心脏的系统和方法是基于血液动力学。 感测平均动脉压(MAP)平均右心房压(MRAP),平均右心室压(MRVP),平均左心房压(MLAP),平均左心室压(MLVP)或平均中心静脉压(MCVP)。 监测长期平均基线压力,如果短期电流平均压力不同于预定值,则进行血液动力学妥协,心脏复律/除颤的指示。 在第二个实施方案中,确定平均基线和平均当前压力之间的差异是否在速率标准(例如高于155bpm的心率以上)之后进行。在第三实施例中,速率和压力标准两者都必须存在 在第四实施例中,使用微处理器,该系统可与抗心动过速和/或抗心动过缓起搏器整合。