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    • 32. 发明授权
    • Multimode system for monitoring and treating a malfunctioning heart
    • 用于监测和治疗故障心脏的多模系统
    • US5269301A
    • 1993-12-14
    • US963113
    • 1992-10-19
    • Todd J. Cohen
    • Todd J. Cohen
    • A61N1/365A61N1/39A61N1/36
    • A61N1/36564A61N1/3918A61N1/3962
    • A system for monitoring a patient and treating the malfunctioning heart of the patient, either in an automatic mode or in a semiautomatic mode, includes means which derive at least one electrical signal resulting from action of the patient's heart and means which derive at least one physiologic signal from or related to the patient's circulatory system. A central processing unit, which may be a programmable microprocessor, with a RAM and a ROM, receives and responds to the at least one electrical signal and to the at least one physiologic signal. Output means, which may include a heart assist pump, pacers, drug delivery devices and cardioverting/-defibrillating apparatuses, controlled by the central processing unit provides corrective measure(s) to the patient. Adjustable or variable baselines, against which a representation of the current, short-term magnitude of the selected physiologic parameter or parameters are provided. The variable baseline(s) is (are) a representation of the selected physiologic parameter(s) determined over a long term of greater duration than the short term over which the current magnitude(s) of the parameter(s) is (are) measured. In its monitoring only mode,the system monitors vital signs and/or the like, including the above-mentioned electrical signal and the physiologic signal and displays them on a monitor.
    • 用于监测患者并以自动模式或半自动模式治疗患者心脏的系统包括导出由患者心脏的作用产生的至少一个电信号的装置,以及导致至少一个生理学 来自或与患者循环系统相关的信号。 可以是RAM和ROM的可编程微处理器的中央处理单元接收并响应至少一个电信号和至少一个生理信号。 输出装置,其可以包括由中央处理单元控制的心脏辅助泵,扑帕器,药物递送装置和心脏复律/去纤颤装置,向患者提供校正措施。 可调或可变的基线,提供所选生理参数或参数的当前短期幅度的表示。 可变基线是(a)所选择的生理参数的表示,该选择的生理参数在长期内比在参数的当前幅度(s)短的短期内确定的长期持续时间, 测量。 在其仅监控模式下,系统监视生命体征等,包括上述电信号和生理信号,并将其显示在监视器上。
    • 34. 发明授权
    • Hemodynamically responsive system for and method of treating a
malfunctioning heart
    • 血液动力学反应系统和治疗失败的心脏的方法
    • US4967749A
    • 1990-11-06
    • US233367
    • 1988-08-18
    • Todd J. Cohen
    • Todd J. Cohen
    • A61N1/365A61N1/39
    • A61N1/3962A61N1/36564A61N1/3918
    • A system for and method of treating a malfunctioning heart is based on hemodynamics, the pressure at a site in a patient's circulatory system being sensed. A signal is developed representative of short term mean arterial pressure (MAP), mean right atrial pressure (MRAP), mean right ventricle pressure (MRVP), mean left atrial pressure (MLAP), mean left ventrical pressure (MLVP) or mean central venous pressure (MCVP). A signal representative of fixed baseline pressure is provided and if the short term current mean pressure differs therefrom by a predetermined value, an indication of hemodynamic compromise, cardioversion/defibrillation is effected. In a second embodiment, the determination of whether the difference between fixed baseline pressure and mean current pressure is undertaken after a rate criteria (for example a heart rate above 155 b.p.m.) has been met. In a third embodiment, the rate and pressure criteria both must exist at the same time, before cardioverting/difibrillation is initiated. In a fourth embodiment, a microprocessor is used. The system may be integrated with antitachycardia and/or antibradycardia pacemakers.
    • 用于治疗故障心脏的系统和方法基于血液动力学,被感测的患者循环系统中的部位处的压力。 代表短期平均动脉压(MAP),平均右心房压(MRAP),平均右心室压(MRVP),平均左心房压(MLAP),平均左心室压(MLVP)或平均中心静脉 压力(MCVP)。 提供代表固定基线压力的信号,如果短期电流平均压力与预定值不同,则进行血液动力学妥协,心脏复律/除颤的指征。 在第二实施例中,在满足速率标准(例如高于155b.p.m.的心率)之后是否进行固定基线压力和平均当前压力之间的差异的确定。 在第三实施例中,速率和压力标准两者必须同时存在于心脏转复/双颤前开始。 在第四实施例中,使用微处理器。 该系统可以与抗心动过速和/或抗心动过缓起搏器整合。
    • 36. 发明授权
    • Remotely controlled catheter insertion system
    • 遥控导管插入系统
    • US09205227B2
    • 2015-12-08
    • US13461463
    • 2012-05-01
    • Todd J. CohenMichael Eilenberg
    • Todd J. CohenMichael Eilenberg
    • A61M25/092A61M25/01A61B19/00
    • A61M25/0105A61B34/30A61B2034/301A61M25/0133
    • A remotely controlled insertion system for a medical device is described. The system comprises a robotic device and a remote control mechanism. The robotic device has a handle controller to receive and hold the control handle or proximal end of a medical device. The medical device is capable of moving in up to six ranges of motion. In one embodiment a first motor is connected through a drive screw to a handle controller to move the medical device forward and backward. A second motor is connected to drive wheels effective to rotate the medical device clockwise and counter-clockwise. A third motor drives a series of gears that are connected to one or more control members on the medical device, this being effective to deflect a tip of the medical device so that movement of the third motor causes such deflection. A control unit is connected to all three motors.
    • 描述了用于医疗设备的遥控插入系统。 该系统包括机器人装置和远程控制机构。 机器人装置具有手柄控制器以接收和保持医疗装置的控制手柄或近端。 医疗设备能够在多达六个运动范围内移动。 在一个实施例中,第一电动机通过驱动螺杆连接到手柄控制器以使医疗装置向前和向后移动。 第二马达连接到驱动轮,有效地顺时针和逆时针旋转医疗装置。 第三马达驱动连接到医疗装置上的一个或多个控制构件的一系列齿轮,这有效地使医疗装置的尖端偏转,使得第三马达的运动引起这种偏转。 控制单元连接到所有三台电机。
    • 38. 发明申请
    • METHOD AND SYSTEM FOR SWITCHING SHOCK VECTORS AND DECREASING TRANSTHORACIC IMPEDANCE FOR CARDIOVERSION AND DEFIBRILLATION
    • 用于切换震动矢量的方法和系统,并减少用于放大和缩小的波动阻抗
    • US20140163663A1
    • 2014-06-12
    • US14102967
    • 2013-12-11
    • Piyush PoddarAaron Jiunhao ChangMelinda ChenPeter MalamasSandya SubramanianTodd J. Cohen
    • Piyush PoddarAaron Jiunhao ChangMelinda ChenPeter MalamasSandya SubramanianTodd J. Cohen
    • A61N1/04
    • A61N1/0476A61N1/046A61N1/0492A61N1/3918
    • A method and system for improving the effectiveness of cardioversion or defibrillation through the ability to switch shock vectors and to reduce transthoracic impedance. A “shock vector” or “shocking vector” is herein defined as the path and direction which electrical current follows in traversing a patient body cavity between two external adhesive electrode patches. An external multiple patch system comprises at least two options for a shocking vector once external patches are applied and adhered to desired locations on a patient's body. A manual switching mechanism in the system provides the ability to direct current from a defibrillator to either of two or more specified shocking vectors. A method and system of decreasing transthoracic impedance comprises wrapping material around a patient's body to apply pressure to adhered patches. This mechanism further reduces transthoracic impedance by increasing effective pressure on the patches through use of pressure-focusing mechanisms located between a patch and a strap. An integrated mechanism would provide qualitative and/or quantitative feedback on the force being applied to the desired patches.
    • 一种通过切换冲击载体和减少经胸阻抗的能力来提高心脏复律或除颤效果的方法和系统。 “震动矢量”或“震动矢量”在此被定义为在两个外部粘合剂电极贴片之间穿过患者体腔时电流所遵循的路径和方向。 一旦外部贴片被施加并且附着到患者​​身体上的期望位置,外部多重贴片系统包括用于令人震惊的矢量的至少两个选项。 系统中的手动切换机制提供了将电流从除颤器引导到两个或更多个指定的震动矢量中的任何一个的能力。 减少经胸阻抗的方法和系统包括围绕患者身体缠绕材料以对附着的贴片施加压力。 该机制通过使用位于贴片和带之间的压力聚焦机构,通过增加贴片上的有效压力来进一步减少经胸阻抗。 综合机制将为施加到所需贴片上的力量提供定性和/或定量的反馈。
    • 40. 发明申请
    • Remotely Controlled Catheter Insertion System
    • 遥控导管插入系统
    • US20120220931A1
    • 2012-08-30
    • US13461463
    • 2012-05-01
    • Todd J. CohenMichael Eilenberg
    • Todd J. CohenMichael Eilenberg
    • A61M25/092
    • A61M25/0105A61B34/30A61B2034/301A61M25/0133
    • A remotely controlled insertion system for a medical device is described. The system comprises a robotic device and a remote control mechanism. The robotic device has a handle controller to receive and hold the control handle or proximal end of a medical device. The medical device is capable of moving in up to six ranges of motion. In one embodiment a first motor is connected through a drive screw to a handle controller to move the medical device forward and backward. A second motor is connected to drive wheels effective to rotate the medical device clockwise and counter-clockwise. A third motor drives a series of gears that are connected to one or more control members on the medical device, this being effective to deflect a tip of the medical device so that movement of the third motor causes such deflection. A control unit is connected to all three motors.
    • 描述了用于医疗设备的遥控插入系统。 该系统包括机器人装置和远程控制机构。 机器人装置具有手柄控制器以接收和保持医疗装置的控制手柄或近端。 医疗设备能够在多达六个运动范围内移动。 在一个实施例中,第一电动机通过驱动螺杆连接到手柄控制器以使医疗装置向前和向后移动。 第二马达连接到驱动轮,有效地顺时针和逆时针旋转医疗装置。 第三马达驱动连接到医疗装置上的一个或多个控制构件的一系列齿轮,这有效地使医疗装置的尖端偏转,使得第三马达的运动引起这种偏转。 控制单元连接到所有三台电机。