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31. 发明授权

US07514544B2 Corn event TC1507 and methods for detection thereof 有权
标题翻译：玉米事件TC1507及其检测方法
公开(公告)号：US07514544B2
公开(公告)日：2009-04-07
申请号：US11774236
申请日：2007-07-06
申请人： Eric Barbour , James Wayne Bing , Guy A. Cardineau , Robert F. Cressman, Jr. , Manju Gupta , Mary E. Hartnett Locke , David Hondred , Joseph W. Keaschall , Michael G. Koziel , Terry EuClaire Meyer , Daniel Moellenbeck , Kenneth Edwin Narva , Wilas Nirunsuksiri , Steven W. Ritchie , Marjorie L. Rudert , Craig D. Sanders , Aihua Shao , Steven Jeffrey Stelman , David S. Stucker , Laura Ann Tagliani , William M. Van Zante
发明人： Eric Barbour , James Wayne Bing , Guy A. Cardineau , Robert F. Cressman, Jr. , Manju Gupta , Mary E. Hartnett Locke , David Hondred , Joseph W. Keaschall , Michael G. Koziel , Terry EuClaire Meyer , Daniel Moellenbeck , Kenneth Edwin Narva , Wilas Nirunsuksiri , Steven W. Ritchie , Marjorie L. Rudert , Craig D. Sanders , Aihua Shao , Steven Jeffrey Stelman , David S. Stucker , Laura Ann Tagliani , William M. Van Zante
IPC分类号： C07H21/02
CPC分类号： C12Q1/6895 , C12N15/8277 , C12N15/8286 , C12Q1/686 , C12Q2600/13 , C12Q2600/16 , Y02A40/162 , Y10S435/975
摘要： The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize TC1507 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
摘要翻译：本发明提供了涉及转基因抗虫玉米植物的DNA组合物。还提供了基于插入到玉米基因组中的重组构建体的DNA序列和插入位点侧翼的DNA序列来检测玉米TC1507事件的存在的测定法。提供了用于进行测定的试剂盒和条件。

32. 发明申请

US20080132690A1 Corn Event TC1507 and Methods for Detection Thereof 有权
公开(公告)号：US20080132690A1
公开(公告)日：2008-06-05
申请号：US11872757
申请日：2007-10-16
申请人： Eric Barbour , James Wayne Bing , Guy A. Cardineau , Robert F. Cressman , Manju Gupta , Mary E. Hartnett Locke , David Hondred , Joseph W. Keaschall , Michael G. Koziel , Terry EuClaire Meyer , Daniel Moellenbeck , Kenneth Edwin Narva , Wilas Nirunsuksiri , Steven W. Ritchie , Marjorie L. Rudert , Craig D. Sanders , Aihua Shao , Steven Jeffrey Stelman , David S. Stucker , Laura Ann Tagliani , William M. Van Zante
发明人： Eric Barbour , James Wayne Bing , Guy A. Cardineau , Robert F. Cressman , Manju Gupta , Mary E. Hartnett Locke , David Hondred , Joseph W. Keaschall , Michael G. Koziel , Terry EuClaire Meyer , Daniel Moellenbeck , Kenneth Edwin Narva , Wilas Nirunsuksiri , Steven W. Ritchie , Marjorie L. Rudert , Craig D. Sanders , Aihua Shao , Steven Jeffrey Stelman , David S. Stucker , Laura Ann Tagliani , William M. Van Zante
IPC分类号： C07H21/04
CPC分类号： C12Q1/6895 , C12N15/8277 , C12N15/8286 , C12Q1/686 , C12Q2600/13 , C12Q2600/16 , Y02A40/162 , Y10S435/975
摘要： The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize TC1507 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.

33. 发明授权

US07309785B1 Modified chimeric Cry35 proteins 有权
标题翻译：修饰的嵌合Cry35蛋白
公开(公告)号：US07309785B1
公开(公告)日：2007-12-18
申请号：US10956448
申请日：2004-10-01
申请人： H. Ernest Schnepf , Kenneth Edwin Narva , Steven Lee Evans
发明人： H. Ernest Schnepf , Kenneth Edwin Narva , Steven Lee Evans
IPC分类号： C07H19/16 , C07K14/00
CPC分类号： C07K14/325
摘要： This invention provides modified, insecticidal Cry35 proteins with enhanced properties as compared to wild-type Cry35 proteins. The modifications to these proteins were based in part on analysis of the atomic coordinates and three-dimensional (3D) structure of the ˜45 kDa 149B1 protein and other proteins in the Cry35 class. The subject invention also includes polynucleotides that encode these modified proteins, and transgenic plants that produce these modified proteins. This invention further provides methods of controlling plant pests, including rootworms, with these modified proteins. The modified proteins of the subject invention include chimeric toxins involving exchanged segments, domains, and motifs as discussed herein. The subject invention also provides methods of modifying Cry35 proteins.
摘要翻译：本发明提供与野生型Cry35蛋白相比具有增强性质的改良的杀虫Cry35蛋白。对这些蛋白质的修饰部分地基于Cry35类中〜45kDa 149B1蛋白质和其他蛋白质的原子坐标和三维（3D）结构的分析。本发明还包括编码这些修饰蛋白质的多核苷酸，以及产生这些修饰蛋白质的转基因植物。本发明还提供了用这些修饰蛋白质控制植物害虫（包括根虫）的方法。本发明的修饰蛋白包括涉及交换的片段，结构域和基序的嵌合毒素，如本文所讨论的。本发明还提供了修饰Cry35蛋白的方法。

34. 发明申请

US20100222273A1 MODIFIED CRY35 PROTEINS 有权
标题翻译：改良CRY35蛋白
公开(公告)号：US20100222273A1
公开(公告)日：2010-09-02
申请号：US12715744
申请日：2010-03-02
申请人： H. Ernest Schnepf , Kenneth Edwin Narva , Steven Lee Evans
发明人： H. Ernest Schnepf , Kenneth Edwin Narva , Steven Lee Evans
IPC分类号： A01N37/18 , C07K14/32 , C12N15/31 , A01H5/00 , A01H5/10 , C07K1/107 , A01P17/00
CPC分类号： C07K14/325
摘要： This invention provides modified, insecticidal Cry35 proteins with enhanced properties as compared to wild-type Cry35 proteins. The modifications to these proteins were based in part on analysis of the atomic coordinates and three-dimensional (3D) structure of the ˜45 kDa 149B1 protein and other proteins in the Cry35 class. The subject invention also includes polynucleotides that encode these modified proteins, and transgenic plants that produce these modified proteins. This invention further provides methods of controlling plant pests, including rootworms, with these modified proteins. The modified proteins of the subject invention include chimeric toxins involving exchanged segments, domains, and motifs as discussed herein. The subject invention also provides methods of modifying Cry35 proteins.
摘要翻译：本发明提供与野生型Cry35蛋白相比具有增强性质的改良的杀虫Cry35蛋白。对这些蛋白质的修饰部分基于Cry35类中〜45kDa 149B1蛋白质和其他蛋白质的原子坐标和三维（3D）结构的分析。本发明还包括编码这些修饰蛋白质的多核苷酸，以及产生这些修饰蛋白质的转基因植物。本发明还提供了用这些修饰蛋白质控制植物害虫（包括根虫）的方法。本发明的修饰蛋白包括涉及交换的片段，结构域和基序的嵌合毒素，如本文所讨论的。本发明还提供了修饰Cry35蛋白的方法。

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