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41. 发明授权

US08090438B2 Method of implanting a subcutaneous defibrillator 有权
标题翻译：植入皮下除颤器的方法
公开(公告)号：US08090438B2
公开(公告)日：2012-01-03
申请号：US12781668
申请日：2010-05-17
申请人： Gust H. Bardy , Riccardo Cappato
发明人： Gust H. Bardy , Riccardo Cappato
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61B5/042 , A61N1/36521 , A61N1/375 , A61N1/3756 , A61N1/3906
摘要： A subcutaneous implantable cardioverter-defibrillator is disclosed which has an electrically active canister which houses a source of electrical energy, a capacitor, and operational circuitry that senses the presence of potentially fatal heart rhythms. At least one subcutaneous electrode that serves as the opposite electrode from the canister is attached to the canister via a lead system. Cardioversion-defibrillation energy is delivered when the operational circuitry senses a potentially fatal heart rhythm. There are no transvenous, intracardic, or epicardial electrodes. A method of subcutaneously implanting the cardioverter-defibrillator is also disclosed as well as a kit for conducting the method.
摘要翻译：公开了一种皮下植入式心律转复除颤器，其具有容纳电能源的电活性罐，电容器和感测潜在致命心律的存在的操作电路。用作与罐相反的电极的至少一个皮下电极通过引导系统附接到罐。当操作电路感测到潜在的致命心律时，可以传递心律转复 - 除颤能量。没有静脉，心内或心外膜电极。还公开了皮下植入心律转复除颤器的方法以及用于进行该方法的试剂盒。

42. 发明授权

US08014862B2 Anterior active housing subcutaneous positioning methods 有权
标题翻译：前活动房皮下定位方法
公开(公告)号：US08014862B2
公开(公告)日：2011-09-06
申请号：US12945853
申请日：2010-11-13
申请人： Alan H. Ostroff , Paul Erlinger , Gust H. Bardy
发明人： Alan H. Ostroff , Paul Erlinger , Gust H. Bardy
IPC分类号： A61N1/00
CPC分类号： A61N1/3956 , A61N1/375 , A61N1/3756 , A61N1/3906 , A61N1/3918 , A61N1/3968 , A61N1/3975
摘要： A subcutaneous cardiac device includes a subcutaneous electrode and a housing coupled to the subcutaneous electrode by a lead with a lead wire. The subcutaneous electrode is adapted to be implanted in a frontal region of the patient so as to overlap a portion of the patient's heart.
摘要翻译：皮下心脏装置包括皮下电极和通过具有引线的引线耦合到皮下电极的壳体。皮下电极适于植入患者的正面区域，以便与患者心脏的一部分重叠。

43. 发明授权

US07953489B2 Multiple electrode vectors for implantable cardiac treatment devices 有权
标题翻译：用于可植入心脏治疗装置的多个电极载体
公开(公告)号：US07953489B2
公开(公告)日：2011-05-31
申请号：US12627861
申请日：2009-11-30
申请人： Jay A. Warren , Gust H. Bardy
发明人： Jay A. Warren , Gust H. Bardy
IPC分类号： A61N1/00
CPC分类号： A61B5/0424 , A61B5/0402 , A61B5/042 , A61B5/04288 , A61B5/076 , A61B5/7207 , A61N1/3622 , A61N1/3925
摘要： The implantable cardiac treatment system of the present invention is capable of choosing the most appropriate electrode vector to sense within a particular patient. In certain embodiments, the implantable cardiac treatment system determines the most appropriate electrode vector for continuous sensing based on which electrode vector results in the greatest signal amplitude, or some other useful metric such as signal-to-noise ratio (SNR). The electrode vector possessing the highest quality as measured using the metric is then set as the default electrode vector for sensing. Additionally, in certain embodiments of the present invention, a next alternative electrode vector is selected based on being generally orthogonal to the default electrode vector. In yet other embodiments of the present invention, the next alternative electrode vector is selected based on possessing the next highest quality metric after the default electrode vector. In some embodiments, if analysis of the default vector is ambiguous, the next alternative electrode vector is analyzed to reduce ambiguity.
摘要翻译：本发明的可植入心脏治疗系统能够选择最合适的电极载体以在特定患者体内感测。在某些实施例中，可植入心脏治疗系统基于哪个电极向量导致最大的信号幅度或诸如信噪比（SNR）的一些其他有用的度量来确定用于连续感测的最合适的电极向量。使用度量测量的具有最高质量的电极矢量然后被设置为用于感测的默认电极矢量。另外，在本发明的某些实施例中，基于大致正交于默认电极向量来选择下一个备选电极矢量。在本发明的其它实施例中，基于在默认电极向量之后拥有下一个最高质量度量来选择下一个备选电极矢量。在一些实施例中，如果默认矢量的分析是不明确的，则分析下一个替代电极矢量以减少模糊度。

44. 发明申请

US20100228306A1 Method of Implanting a Subcutaneous Defibrillator 有权
标题翻译：植入皮下除颤器的方法
公开(公告)号：US20100228306A1
公开(公告)日：2010-09-09
申请号：US12781668
申请日：2010-05-17
申请人： Gust H. Bardy , Riccardo Cappato
发明人： Gust H. Bardy , Riccardo Cappato
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61B5/042 , A61N1/36521 , A61N1/375 , A61N1/3756 , A61N1/3906
摘要： A subcutaneous implantable cardioverter-defibrillator is disclosed which has an electrically active canister which houses a source of electrical energy, a capacitor, and operational circuitry that senses the presence of potentially fatal heart rhythms. At least one subcutaneous electrode that serves as the opposite electrode from the canister is attached to the canister via a lead system. Cardioversion-defibrillation energy is delivered when the operational circuitry senses a potentially fatal heart rhythm. There are no transvenous, intracardic, or epicardial electrodes. A method of subcutaneously implanting the cardioverter-defibrillator is also disclosed as well as a kit for conducting the method.
摘要翻译：公开了一种皮下植入式心律转复除颤器，其具有容纳电能源的电活性罐，电容器和感测潜在致命心律的存在的操作电路。用作与罐相反的电极的至少一个皮下电极通过引导系统附接到罐。当操作电路感测到潜在的致命心律时，可以传递心律转复 - 除颤能量。没有静脉，心内或心外膜电极。还公开了皮下植入心律转复除颤器的方法以及用于进行该方法的试剂盒。

45. 发明申请

US20100137930A1 Subcutaneous Electrode with Improved Contact Shape for Transthoracic Conduction 有权
标题翻译：具有改善的胸廓传导接触形状的皮下电极
公开(公告)号：US20100137930A1
公开(公告)日：2010-06-03
申请号：US12698609
申请日：2010-02-02
申请人： Gust H. Bardy , Riccardo Cappato , William J. Rissmann , Gary H. Sanders
发明人： Gust H. Bardy , Riccardo Cappato , William J. Rissmann , Gary H. Sanders
IPC分类号： A61N1/39 , A61N1/05
CPC分类号： A61N1/3962 , A61N1/05 , A61N1/0563 , A61N1/375 , A61N1/3752 , A61N1/3756 , A61N1/3906 , A61N1/3956 , A61N1/3968 , A61N1/3975
摘要： One embodiment of the present invention provides a lead electrode assembly for use with an implantable cardioverter-defibrillator subcutaneously implanted outside the ribcage between the third and twelfth ribs comprising the electrode.
摘要翻译：本发明的一个实施例提供了一种用于与包括电极的第三和第十二肋之间的胸腔外的植入式心律转复除颤器一起使用的引线电极组件。

46. 发明申请

US20100004713A1 Methods and Devices for Accurately Classifying Cardiac Activity 有权
标题翻译：准确分类心脏活动的方法和设备
公开(公告)号：US20100004713A1
公开(公告)日：2010-01-07
申请号：US12437547
申请日：2009-05-07
申请人： Jay A. Warren , Rick Sanghera , Venugopoal Allavatam , Surekha Palreddy
发明人： Jay A. Warren , Rick Sanghera , Venugopoal Allavatam , Surekha Palreddy
IPC分类号： A61N1/365
CPC分类号： A61B5/4836 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0468 , A61B5/7203 , A61B5/7221 , A61B5/726 , A61B5/7264 , A61N1/3621 , A61N1/36514 , A61N1/36592 , A61N1/37 , A61N1/3987
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. Several examples emphasize the use of morphology analysis using correlation to static templates and/or inter-event correlation analysis.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在一些示例中，分析包括检测到的事件的捕获数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。几个例子强调使用与静态模板和/或事件间相关分析相关的形态分析。

47. 发明申请

US20090228057A1 Accurate Cardiac Event Detection in an Implantable Cardiac Stimulus Device 有权
标题翻译：可植入心脏刺激装置中精确的心脏事件检测
公开(公告)号：US20090228057A1
公开(公告)日：2009-09-10
申请号：US12399901
申请日：2009-03-06
申请人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
发明人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
IPC分类号： A61N1/362
CPC分类号： A61N1/3987 , A61B5/0245 , A61B5/0452 , A61B5/04525 , A61B5/726 , A61N1/365 , A61N1/3704
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some illustrative examples, detected events are analyzed to identify changes in detected event amplitudes. When detected event amplitudes are dissimilar from one another, a first set of detection parameters may be invoked, and, when detected event amplitudes are similar to one another, a second set of detection parameters may be invoked. Additional methods determine whether the calculated heart rate is “high” or “low,” and then may select a third set of detection parameters for use when the calculated heart rate is high.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在一些说明性示例中，分析检测到的事件以识别检测到的事件振幅的变化。当检测到的事件幅度彼此不同时，可以调用第一组检测参数，并且当检测到的事件幅度彼此相似时，可以调用第二组检测参数。另外的方法确定计算的心率是“高”还是“低”，然后可以选择第三组检测参数，以便在计算心率高时使用。

48. 发明申请

US20090198296A1 Adaptive Shock Delivery in an Implantable Cardiac Stimulus Device 有权
标题翻译：可植入心脏刺激装置中的自适应冲击输送
公开(公告)号：US20090198296A1
公开(公告)日：2009-08-06
申请号：US12363425
申请日：2009-01-30
申请人： Rick SANGHERA , Jay A. Warren
发明人： Rick SANGHERA , Jay A. Warren
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3686
摘要： Methods and devices that are configured to deliver cardiac stimuli in a particular fashion. In an illustrative embodiment, a method is used wherein a first stimulus is delivered using a first polarity, and, if the first stimulus fails to successfully convert an arrhythmia, a second stimulus having a second polarity that is different from or opposite of the first polarity is then delivered. Subsequent stimuli, if needed, are delivered in a continuing alternating-polarity manner. The first polarity may be determined by observing whether successfully-converting stimulus has been delivered previously and, if so, the polarity of the most recent stimulus that resulted in successful conversion is used as the first polarity. In additional embodiments, electrode configuration may be changed instead of or in addition to polarity, following unsuccessful stimulus delivery. Devices configured to perform such methods are included in additional illustrative embodiments.
摘要翻译：被配置为以特定方式递送心脏刺激的方法和装置。在说明性实施例中，使用其中使用第一极性传送第一刺激的方法，并且如果第一刺激不能成功转换心律失常，则具有与第一极性不同或相反的第二极性的第二刺激然后交付。如果需要，随后的刺激以连续的交替极性方式递送。第一极性可以通过观察成功转换刺激是否已经被传递来确定，如果是，则将导致成功转换的最近的刺激的极性用作第一极性。在另外的实施例中，在不成功的刺激递送之后，可以改变电极配置而不是极性或除了极性之外。被配置为执行这些方法的装置包括在另外的说明性实施例中。

49. 发明申请

US20090187227A1 Data Manipulation Following Delivery of a Cardiac Stimulus in an Implantable Cardiac Stimulus Device 有权
标题翻译：在可植入的心脏刺激装置中传递心脏刺激后的数据操作
公开(公告)号：US20090187227A1
公开(公告)日：2009-07-23
申请号：US12355552
申请日：2009-01-16
申请人： Surekha Palreddy , Venugopal Allavatam
发明人： Surekha Palreddy , Venugopal Allavatam
IPC分类号： A61N1/365
CPC分类号： A61N1/3943 , A61B5/0468 , A61N1/0504 , A61N1/3704 , A61N1/3756 , A61N1/3925 , A61N1/3987
摘要： Methods of cardiac rhythm analysis in an implantable cardiac stimulus device, and devices configured for such methods. In an illustrative embodiment, certain data relating to cardiac event rate or amplitude is modified following delivery of a cardiac stimulus. In another embodiment, cardiac rhythm analysis is performed using one of plural states, with the plural states using different criteria, such as a detection threshold, to detect cardiac events in a sensed signal. Following delivery of a cardiac stimulus, data is manipulated to force the analysis into one of the states, where stimulus is delivered, in the illustrative embodiment, only after a different state is invoked. Implantable devices incorporating operational circuitry for performing such methods are also included in other illustrative embodiments.
摘要翻译：可植入心脏刺激装置中的心律分析方法以及为这种方法配置的装置。在说明性实施例中，在心脏刺激递送之后修改与心脏事件发生率或幅度有关的某些数据。在另一个实施例中，使用多个状态中的一个来执行心律分析，其中多个状态使用不同的标准，例如检测阈值，以检测感测信号中的心脏事件。在递送心脏刺激之后，仅在不同状态被调用之后，数据被操纵以迫使分析进入在说明性实施例中传送刺激的状态之一。包含用于执行这些方法的操作电路的可植入装置也包括在其它说明性实施例中。

50. 发明授权

US07522957B2 Defibrillation pacing circuitry 有权
标题翻译：除颤起搏电路
公开(公告)号：US07522957B2
公开(公告)日：2009-04-21
申请号：US11146607
申请日：2005-06-07
申请人： Alan H. Ostroff
发明人： Alan H. Ostroff
IPC分类号： A61N1/39
CPC分类号： A61N1/3962 , A61N1/362 , A61N1/3912
摘要： Electrical circuit componentry is switchable into a defibrillator circuit to deliver a constant pacing current to a patient. The circuitry may include a constant current source inserted in a leg of the defibrillator circuit or a resistor of selected value inserted between a high voltage source and the high side of a defibrillator circuit.
摘要翻译：电路组件可切换到除颤器电路中，以向患者输送恒定的起搏电流。电路可以包括插入在除颤器电路的腿部的恒定电流源或插入在高电压源和除颤器电路的高侧之间的选定值的电阻器。

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