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1. 发明授权

US08437838B2 Methods and devices for identifying overdetection of cardiac signals 有权
标题翻译：识别心脏信号过度检测的方法和装置
公开(公告)号：US08437838B2
公开(公告)日：2013-05-07
申请号：US13607256
申请日：2012-09-07
申请人： Jay A. Warren , Venugopal Allavatam , Rick Sanghera , Surekha Palreddy
发明人： Jay A. Warren , Venugopal Allavatam , Rick Sanghera , Surekha Palreddy
IPC分类号： A61B5/04 , A61B5/02 , A61N1/00
CPC分类号： A61B5/0452 , A61B5/0424 , A61B5/726
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, sensed data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在说明性示例中，分析包括检测到的事件的感测数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。

2. 发明授权

US08244349B2 Adaptive shock delivery in an implantable cardiac stimulus device 有权
标题翻译：可植入心脏刺激装置中的自适应冲击输送
公开(公告)号：US08244349B2
公开(公告)日：2012-08-14
申请号：US12363425
申请日：2009-01-30
申请人： Rick Sanghera , Jay A. Warren
发明人： Rick Sanghera , Jay A. Warren
IPC分类号： A61N1/362
CPC分类号： A61N1/3956 , A61N1/3686
摘要： Methods and devices that are configured to deliver cardiac stimuli in a particular fashion. In an illustrative embodiment, a method is used wherein a first stimulus is delivered using a first polarity, and, if the first stimulus fails to successfully convert an arrhythmia, a second stimulus having a second polarity that is different from or opposite of the first polarity is then delivered. Subsequent stimuli, if needed, are delivered in a continuing alternating-polarity manner. The first polarity may be determined by observing whether successfully-converting stimulus has been delivered previously and, if so, the polarity of the most recent stimulus that resulted in successful conversion is used as the first polarity. In additional embodiments, electrode configuration may be changed instead of or in addition to polarity, following unsuccessful stimulus delivery. Devices configured to perform such methods are included in additional illustrative embodiments.
摘要翻译：被配置为以特定方式递送心脏刺激的方法和装置。在说明性实施例中，使用其中使用第一极性传送第一刺激的方法，并且如果第一刺激不能成功转换心律失常，则具有与第一极性不同或相反的第二极性的第二刺激然后交付。如果需要，随后的刺激以连续的交替极性方式递送。第一极性可以通过观察成功转换刺激是否已经被传递来确定，如果是，则将导致成功转换的最近的刺激的极性用作第一极性。在另外的实施例中，在不成功的刺激递送之后，可以改变电极配置而不是极性或除了极性之外。被配置为执行这些方法的装置包括在另外的说明性实施例中。

3. 发明申请

US20120197334A1 Methods and Devices for Accurately Classifying Cardiac Activity 有权
标题翻译：准确分类心脏活动的方法和设备
公开(公告)号：US20120197334A1
公开(公告)日：2012-08-02
申请号：US13436448
申请日：2012-03-30
申请人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam , Surekha Palreddy
发明人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam , Surekha Palreddy
IPC分类号： A61N1/365
CPC分类号： A61B5/4836 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0468 , A61B5/7203 , A61B5/7221 , A61B5/726 , A61B5/7264 , A61N1/3621 , A61N1/36514 , A61N1/36592 , A61N1/37 , A61N1/3987
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. Several examples emphasize the use of morphology analysis using correlation to static templates and/or inter-event correlation analysis.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在一些示例中，分析包括检测到的事件的捕获数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。几个例子强调使用与静态模板和/或事件间相关分析相关的形态分析。

4. 发明申请

US20100331904A1 Adaptive Confirmation of Treatable Arrhythmia in Implantable Cardiac Stimulus Devices 有权
标题翻译：可植入心脏刺激装置中可治疗性心律失常的自适应确认
公开(公告)号：US20100331904A1
公开(公告)日：2010-12-30
申请号：US12826241
申请日：2010-06-29
申请人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
发明人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
IPC分类号： A61N1/39 , A61N1/365
CPC分类号： A61N1/3987 , A61B5/0464 , A61N1/3622 , A61N1/3925 , A61N1/3943 , A61N1/3956
摘要： Methods and devices for adjusting therapy delivery decisions in an implantable cardiac stimulus device by observing cardiac activity following an initial identification of a treatable condition. In some examples, cardiac activity that appears benign is quantified and a therapy confirmation threshold is adjusted according to how much apparently benign cardiac activity is seen after an initial identification of a treatable condition. In other examples, a new threshold is applied following the initial identification of treatable condition, removing historical data preceding the initial identification from subsequent therapy delivery decisions.
摘要翻译：用于通过在初始识别可治疗病症后观察心脏活动来调整可植入心脏刺激装置中的治疗递送决定的方法和装置。在一些实例中，显示良性的心脏活动被定量，并且根据在可治疗病症的初始鉴定之后看到多少明显良性的心脏活动来调整治疗确认阈值。在其他示例中，在可治疗条件的初始识别之后应用新阈值，从随后的治疗递送决定中移除初始识别之前的历史数据。

5. 发明申请

US20100152799A1 Implantable Defibrillator Systems and Methods with Mitigations for Saturation Avoidance and Accommodation 有权
标题翻译：植入式除颤器系统和缓解饱和度的住院方法
公开(公告)号：US20100152799A1
公开(公告)日：2010-06-17
申请号：US12636575
申请日：2009-12-11
申请人： Rick Sanghera , Venugopal Allavatam , Surekha Palreddy , Jay A. Warren
发明人： Rick Sanghera , Venugopal Allavatam , Surekha Palreddy , Jay A. Warren
IPC分类号： A61N1/39
CPC分类号： A61N1/3704 , A61N1/048 , A61N1/0504 , A61N1/0563 , A61N1/3702 , A61N1/3968 , A61N1/3987
摘要： Methods and implantable devices that address response to, or avoidance of, likely non-cardiac voltages including afterpotentials from external or internal stimulus. Some examples are directed toward methods of operation in implantable medical devices, the methods configured for identifying saturation of input circuitry and mitigating the effects of such saturation. Some examples are directed toward implantable cardiac stimulus or monitoring devices that include methods for identifying saturated conditions and mitigating the effects of such saturation.
摘要翻译：解决可能的非心脏电压（包括来自外部或内部刺激的后电位）的响应或避免的方法和可植入装置。一些示例涉及可植入医疗设备中的操作方法，该方法被配置用于识别输入电路的饱和度并减轻这种饱和的影响。一些示例涉及可植入心脏刺激或监测装置，其包括用于识别饱和状况和减轻这种饱和的影响的方法。

6. 发明授权

US08788023B2 Systems and methods for sensing vector selection in an implantable medical device 有权
标题翻译：用于在可植入医疗装置中感测矢量选择的系统和方法
公开(公告)号：US08788023B2
公开(公告)日：2014-07-22
申请号：US11441522
申请日：2006-05-26
申请人： Rick Sanghera , Venugopal Allavatam
发明人： Rick Sanghera , Venugopal Allavatam
IPC分类号： A61B5/04
CPC分类号： A61B5/04011 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/686 , A61N1/368 , A61N1/3704 , A61N1/37211 , A61N1/3918 , A61N1/3956
摘要： Methods and devices for sensing vector analysis in an implantable cardiac stimulus system. In an illustrative example, a first sensing vector is analyzed to determine whether it is suitable, within given threshold conditions, for use in cardiac event detection and analysis. If so, the first vector may be selected for detection and analysis. Otherwise, one or more additional vectors are analyzed. A detailed example illustrates methods for analyzing sensing vectors by the use of a scoring system. Additional examples include implantable devices, implantable device systems, and/or programmers for use in conjunction with implantable devices, each configured to perform such methods.
摘要翻译：用于在可植入心脏刺激系统中感测矢量分析的方法和装置。在说明性示例中，分析第一感测向量以确定在给定阈值条件内是否适合用于心脏事件检测和分析。如果是这样，可以选择第一个载体进行检测和分析。否则，分析一个或多个附加向量。详细的例子说明了通过使用评分系统来分析感测矢量的方法。另外的示例包括可植入装置，可植入装置系统和/或与可植入装置结合使用的编程器，每个被配置为执行这些方法。

7. 发明申请

US20120271185A1 Robust Rate Calculation in an Implantable Cardiac Stimulus or Monitoring Device 有权
标题翻译：可植入心脏刺激或监测装置中的稳健率计算
公开(公告)号：US20120271185A1
公开(公告)日：2012-10-25
申请号：US13451393
申请日：2012-04-19
申请人： Rick Sanghera , Venugopal Allavatam , Jay A. Warren , Mark R. Schroeder
发明人： Rick Sanghera , Venugopal Allavatam , Jay A. Warren , Mark R. Schroeder
IPC分类号： A61B5/0468
CPC分类号： A61B5/0452 , A61B5/0245 , A61B5/042 , A61B5/046 , A61B5/0468 , A61B5/7203 , A61B5/7221 , A61N1/36592 , A61N1/3704 , A61N1/3956
摘要： Devices and methods for analyzing cardiac signal data. An illustrative method includes identifying a plurality of detected events and measuring intervals between the detected events for use in rate estimation. In the illustrative embodiment, a set of intervals is used to make the rate estimation by first discarding selected intervals from the set. The remaining intervals are then used to calculate an estimated interval, for example by averaging the remaining intervals.
摘要翻译：用于分析心脏信号数据的装置和方法。一种说明性方法包括识别多个检测到的事件并测量检测到的事件之间的间隔，以用于速率估计。在说明性实施例中，使用一组间隔通过首先从组中丢弃所选择的间隔来进行速率估计。然后，剩余的间隔用于计算估计的间隔，例如通过对剩余间隔进行平均。

8. 发明授权

US08265749B2 Methods and devices for accurately classifying cardiac activity 有权
公开(公告)号：US08265749B2
公开(公告)日：2012-09-11
申请号：US12637438
申请日：2009-12-14
申请人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
发明人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
IPC分类号： A61B5/0452
CPC分类号： A61N1/3987 , A61B5/024 , A61B5/04014 , A61B5/0452 , A61B5/6847 , A61B5/726 , A61N1/3704 , A61N1/3956
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. New methods for organizing the use of morphology and rate analysis in an overall architecture for rhythm classification and cardiac signal analysis are also discussed.

9. 发明申请

US20120197147A1 Methods and Devices for Accurately Classifying Cardiac Activity 有权
标题翻译：准确分类心脏活动的方法和设备
公开(公告)号：US20120197147A1
公开(公告)日：2012-08-02
申请号：US13436398
申请日：2012-03-30
申请人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
发明人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
IPC分类号： A61B5/0408 , A61N1/39 , A61N1/365
CPC分类号： A61N1/3987 , A61B5/024 , A61B5/04014 , A61B5/0452 , A61B5/6847 , A61B5/726 , A61N1/3704 , A61N1/3956
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. New methods for organizing the use of morphology and rate analysis in an overall architecture for rhythm classification and cardiac signal analysis are also discussed.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在说明性示例中，分析包括检测到的事件的捕获数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。还讨论了在节律分类和心脏信号分析的整体架构中组织使用形态学和速率分析的新方法。

10. 发明授权

US07783340B2 Systems and methods for sensing vector selection in an implantable medical device using a polynomial approach 有权
标题翻译：使用多项式方法在可植入医疗装置中感测矢量选择的系统和方法
公开(公告)号：US07783340B2
公开(公告)日：2010-08-24
申请号：US11623472
申请日：2007-01-16
申请人： Rick Sanghera , Venugopal Allavatam
发明人： Rick Sanghera , Venugopal Allavatam
IPC分类号： A61B5/04
CPC分类号： A61N1/3702 , A61B5/04011 , A61B5/0422 , A61B5/0452 , A61N1/3918
摘要： Methods and devices configured for analyzing sensing vectors in an implantable cardiac stimulus system. In an illustrative example, a first sensing vector is analyzed to determine whether it is suitable, within given threshold conditions, for use in cardiac event detection and analysis. If so, the first sensing vector may be selected for detection and analysis. Otherwise, and in other examples, one or more additional sensing vectors are analyzed. A polynomial may be used during analysis to generate a metric indicating the suitability of the sensing vector for use in cardiac event detection and analysis. Additional illustrative examples include systems and devices adapted to perform at least these methods, including implantable medical devices, and/or programmers for implantable medical devices, and/or systems having both programmers and implantable medical devices that cooperatively analyze sensing vectors.
摘要翻译：配置用于分析可植入心脏刺激系统中的感测向量的方法和装置。在说明性示例中，分析第一感测向量以确定在给定阈值条件内是否适合用于心脏事件检测和分析。如果是，则可以选择第一感测矢量进行检测和分析。否则，在其他示例中，分析一个或多个附加感测向量。在分析期间可以使用多项式来生成指示用于心脏事件检测和分析的感测矢量的适合性的度量。附加的说明性示例包括适于执行至少这些方法的系统和设备，包括可植入医疗设备和/或用于可植入医疗设备的程序员，和/或具有共同分析感测向量的程序员和可植入医疗设备的系统。

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