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41. 发明授权

US09041770B2 Three-dimensional image capture device 有权
标题翻译：三维图像捕获装置
公开(公告)号：US09041770B2
公开(公告)日：2015-05-26
申请号：US13255386
申请日：2010-12-22
申请人： Masao Hiramoto , Masayuki Misaki , Teruyuki Takizawa , Masaaki Suzuki
发明人： Masao Hiramoto , Masayuki Misaki , Teruyuki Takizawa , Masaaki Suzuki
IPC分类号： G06K9/00 , G02F1/1335 , H04N5/335 , H04N13/02 , G03B35/08 , G03B35/10
CPC分类号： H04N13/211 , G03B35/08 , G03B35/10 , G06K9/00 , H04N13/214
摘要： The present invention provides an image capturing technique for obtaining, at the same time, multiple images with parallax and an image that would cause no sensitivity problem even without mechanically operating any part of its image capturing system.The 3D image capture device of this invention includes: a light transmitting member 2 having a polarizing area A that transmits only a light ray polarized in a particular direction and a non-polarizing area C that transmits any light ray irrespective of its polarization direction; a solid-state image sensor 1 arranged to receive the light ray transmitted through the light transmitting member 2; an imaging section 3 for producing an image on the imaging area 1a of the solid-state image sensor 1; and an image generating section for generating images based on signals supplied from the image sensor 1, which includes a filter array including a polarization filter. The image generating section generates images based on the light rays that have entered the polarizing area A and the non-polarizing area C, respectively.
摘要翻译：本发明提供一种用于同时获得具有视差的多个图像和甚至在不机械地操作其图像捕获系统的任何部分的情况下也不会引起灵敏度问题的图像的图像捕捉技术。本发明的3D图像捕获装置包括：透光构件2，其具有仅透射在特定方向偏振的光线的偏振区域A和透射任何光线而不考虑其偏振方向的非偏振区域C; 固态图像传感器1，被配置为接收透过透光部件2的光线; 用于在固态图像传感器1的成像区域1a上产生图像的成像部分3; 以及图像生成部，用于基于从包括偏振滤波器的滤波器阵列的图像传感器1提供的信号生成图像。图像生成部基于已经进入偏振区域A和非偏振区域C的光线来生成图像。

42. 发明授权

US08933252B2 Method for rapid fluoromethylation and method for preparation of PET tracer using the same 有权
标题翻译：快速氟甲基化方法及使用该方法制备PET示踪剂
公开(公告)号：US08933252B2
公开(公告)日：2015-01-13
申请号：US13513565
申请日：2010-12-03
申请人： Masaaki Suzuki , Hisashi Doi , Miki Goto
发明人： Masaaki Suzuki , Hisashi Doi , Miki Goto
IPC分类号： C07C67/343 , C07D311/30 , A61K51/04 , C07B59/00
CPC分类号： C07D311/30 , A61K51/04 , A61K51/0421 , C07B59/001 , C07B2200/05 , C07C67/343 , C07C69/76
摘要： Provided are: a method for rapid fluoromethylation, by which a fluoromethyl group can be easily bonded to an aromatic-ring carbon of an aromatic compound with little generation of by-products; and a process for preparation of a PET tracer using the same. The method is characterized by cross-coupling an organoboron compound in which an aromatic ring is bonded to a boron atom with FCX2Br (wherein X is ordinary hydrogen or heavy hydrogen) in a solvent obtained by adding water to an aprotic polar solvent, in the presence of a palladium complex, a phosphine ligand, and a base.
摘要翻译：提供：快速氟甲基化的方法，其中氟甲基可以容易地与少量副产物的芳香族化合物的芳香环碳键合; 以及使用其制备PET示踪剂的方法。该方法的特征在于在通过将水添加到非质子极性溶剂中获得的溶剂中，将芳环与硼原子结合的有机硼化合物与FCX2Br（其中X是普通氢或重氢）交联偶联，的钯络合物，膦配体和碱。

43. 发明授权

US08902338B2 Color separation filter array, solid-state imaging element, imaging device, and display device 有权
标题翻译：彩色分离滤光片阵列，固态成像元件，成像装置和显示装置
公开(公告)号：US08902338B2
公开(公告)日：2014-12-02
申请号：US13814260
申请日：2012-05-25
申请人： Masao Hiramoto , Masayuki Misaki , Masaaki Suzuki
发明人： Masao Hiramoto , Masayuki Misaki , Masaaki Suzuki
IPC分类号： H04N3/14 , H04N9/04 , G02B27/10 , G02B27/14
CPC分类号： H04N9/045 , G02B27/1006 , G02B27/141 , G02B27/143
摘要： A color separating filter array has a configuration in which unit elements 1, each having a triangular pyramid shape, are arranged two-dimensionally. Each unit element 1 includes: first, second, and third filters 1R, 1G, 1B arranged to form the three lateral faces of the triangular pyramid; and a reflective region. The first, second and third filters 1R, 1G and 1B are designed to transmit visible radiations falling within first, second and third wavelength ranges, respectively, and reflect visible radiation falling within any other wavelength range. The reflective region is arranged to further reflect a light ray that has been incident on a region surrounded with the first, second and third filters and reflected from any of the first, second and third filters and to guide the reflected light ray to another one of the first, second and third filters that is different from the one that has already reflected the light ray once.
摘要翻译：分色滤色器阵列具有二维排列有各自具有三角锥形状的单位元件1的结构。每个单元元件1包括：布置成形成三角锥的三个侧面的第一，第二和第三滤光器1R，1G，1B; 和反射区域。第一，第二和第三滤光器1R，1G和1B分别被设计成透射落在第一，第二和第三波长范围内的可见光，并且反射落在任何其它波长范围内的可见光。反射区域被布置成进一步反射已经入射在由第一，第二和第三滤光器包围的区域上并从第一，第二和第三滤光器中的任一个反射的区域的光线，并且将反射光线引导到另一个与已经反射光线一次的第一，第二和第三滤光器不同。

44. 发明授权

US08765941B2 Aniline derivative having anti-RNA viral activity 有权
标题翻译：具有抗RNA病毒活性的苯胺衍生物
公开(公告)号：US08765941B2
公开(公告)日：2014-07-01
申请号：US12934206
申请日：2009-02-04
申请人： Hiroshi Onogi , Masatoshi Hagiwara , Masaaki Suzuki , Hiroko Koyama , Takamitsu Hosoya , Toshiyuki Hiramatsu
发明人： Hiroshi Onogi , Masatoshi Hagiwara , Masaaki Suzuki , Hiroko Koyama , Takamitsu Hosoya , Toshiyuki Hiramatsu
IPC分类号： C07D225/02 , C07D401/00 , C07D401/12 , A61K31/395 , C07D213/83 , C07D405/12 , A61K31/55 , A61K31/00 , A61K31/4545 , C07D213/81 , A61K31/455 , C07D213/82 , C07D409/12
CPC分类号： C07D213/81 , A61K31/00 , A61K31/395 , A61K31/4545 , A61K31/455 , A61K31/55 , C07D213/82 , C07D213/83 , C07D225/02 , C07D401/12 , C07D405/12 , C07D409/12
摘要： Viruses, and particularly RNA viruses, have high mutation rates. Hence, antiviral agents that have been developed to date targeting protease or reverse transcriptase of viruses have quickly lost their effectiveness and resistant viruses have emerged. Also, in recent years, viral diseases caused by various new viruses such as SARS, avian influenza, and the hepatitis C have become social menaces. Therefore, the development of a novel antiviral agent that can cope with a virus resistant to an existing drug or a new virus and has a wide range of applications has been demanded. The present invention provides a novel anti-RNA viral agent and a method for use thereof. The present invention further provides an anti-RNA viral agent that is also effective against a new virus or a drug-resistant virus, and a method for use thereof.
摘要翻译：病毒，特别是RNA病毒，具有高突变率。因此，迄今为止开发的针对蛋白酶或病毒逆转录酶的抗病毒药物已经迅速丧失其有效性，并出现了抗性病毒。另外近年来，由SARS，禽流感，丙型肝炎等各种新病毒引起的病毒性疾病已成为社会威胁。因此，需要开发能够应对对现有药物或新病毒有抵抗性的病毒的新型抗病毒剂，并且具有广泛的应用。本发明提供了一种新的抗-RNA病毒剂及其使用方法。本发明还提供了对新病毒或耐药性病毒也有效的抗RNA病毒剂及其使用方法。

45. 发明申请

US20140124650A1 IMAGING DEVICE 有权
标题翻译：成像装置
公开(公告)号：US20140124650A1
公开(公告)日：2014-05-08
申请号：US14008750
申请日：2012-12-18
申请人： Tatsuya Nakamura , Seiji Nishiwaki , Shinichi Wakabayashi , Masaaki Suzuki
发明人： Tatsuya Nakamura , Seiji Nishiwaki , Shinichi Wakabayashi , Masaaki Suzuki
IPC分类号： H01L27/146
CPC分类号： H01L27/14625 , H01L27/14629 , H01L27/14645 , H01L31/0232 , H01L31/02325 , H04N9/045 , H04N9/097
摘要： The imaging device disclosed herein includes: a plurality of photodetection sections 15a and 15b having a light-receiving face, the plurality of photodetection sections 15a and 15b being disposed in a two-dimensional array along a first direction and along a second direction different from the first direction, such that the light-receiving faces of the plurality of photodetection sections constitute an imaging plane; a transparent layer 11 having an incident face and an outgoing face and being disposed so that the outgoing face opposes the imaging plane; and a plurality of spectroscopic sections 12 having a greater refractive index than a refractive index of the transparent layer 11 and being disposed in a two-dimensional array in a plane of arrangement, the plane of arrangement being within the transparent layer and parallel to the imaging plane. Zeroth order diffracted light 13 and ±first order diffracted light 14, derived from light transmitted through each spectroscopic section and a portion of the transparent layer neighboring the spectroscopic section, respectively enter distinct photodetection sections among the plurality of photodetection sections. An interval between two adjacent spectroscopic sections along a predetermined direction is smaller at the periphery than at the center of the imaging plane.
摘要翻译：本文公开的成像装置包括：具有光接收面的多个光电检测部分15a和15b，多个光电检测部分15a和15b沿着第一方向设置成二维阵列，并且沿着与第一方向，使得多个光电检测部分的光接收面构成成像平面; 具有入射面和出射面的透明层11，其设置成使得出射面与成像面相对; 以及多个分光部12具有比透明层11的折射率更大的折射率，并且在布置平面中以二维阵列设置，该布置平面在透明层内并平行于成像飞机衍射自透过每个分光部分的光和邻近分光部分的透明层的一部分的零级衍射光13和±一级衍射光14分别在多个光电检测部分中输入不同的光检测部分。沿着预定方向的两个相邻光谱部分之间的间隔在周边比在成像平面的中心处更小。

46. 发明授权

US08520126B2 Solid-state image capturing element, image capturing device and signal processing method 有权
标题翻译：固态摄像元件，摄像装置及信号处理方法
公开(公告)号：US08520126B2
公开(公告)日：2013-08-27
申请号：US13498598
申请日：2011-04-22
申请人： Masao Hiramoto , Yusuke Monobe , Yoshiaki Sugitani , Masaaki Suzuki
发明人： Masao Hiramoto , Yusuke Monobe , Yoshiaki Sugitani , Masaaki Suzuki
IPC分类号： H04N9/07 , H04N9/83 , H04N9/04 , H04N3/14 , H04N5/335
CPC分类号： H01L27/14625 , H01L27/14621 , H01L27/14645 , H04N9/045 , H04N2209/047
摘要： The solid-state image sensor 10 includes an array of photosensitive cells and an array 100 of dispersing elements. The photosensitive cell array is comprised of unit blocks 40, each including four photosensitive cells 2a, 2b, 2c and 2d. The dispersing element array 100 makes light, obtained by subtracting a light ray with a first color component C1 from the incoming light W and adding a light ray with a second color component C2 to the remainder, incident on the first photosensitive cell 2a, also makes light, obtained by subtracting the light ray with the second color component C1 from the incoming light W and adding the light ray with the first color component C1 to the remainder, incident on the second photosensitive cell 2b, further makes light, obtained by subtracting the light rays with the first and second color components C1+C2 from the incoming light W, incident on the third photosensitive cell 2c, and further makes light, obtained by adding the light rays with the first and second color components C1+C2 to the incoming light W, incident on the fourth photosensitive cell 2d.
摘要翻译：固态图像传感器10包括感光单元阵列和分散元件阵列100。感光单元阵列由单元块40组成，每个单元块40包括四个感光单元2a，2b，2c和2d。分散元件阵列100通过从入射光W减去具有第一颜色成分C1的光线并将入射到第一感光单元2a上的剩余部分中的第二颜色分量C2的光线加入而获得的光也使得通过从入射光W减去具有第二颜色分量C1的光线并将入射到第二感光单元2b上的第一颜色分量C1的光线添加到余数而获得的光进一步使得通过减去来自入射光W的第一和第二颜色分量C1 + C2的光线入射到第三感光单元2c上，并且进一步使通过将第一和第二颜色分量C1 + C2的光线与入射入射到第四感光单元2d上的光W。

47. 发明授权

US08338362B2 Methods for controlling SR protein phosphorylation, and antiviral agents whose active ingredients comprise agents that control SR protein activity 有权
标题翻译：用于控制SR蛋白磷酸化的方法，以及其活性成分包含控制SR蛋白活性的试剂的抗病毒剂
公开(公告)号：US08338362B2
公开(公告)日：2012-12-25
申请号：US12494102
申请日：2009-06-29
申请人： Masatoshi Hagiwara , Takeshi Fukuhara , Masaaki Suzuki , Takamitsu Hosoya
发明人： Masatoshi Hagiwara , Takeshi Fukuhara , Masaaki Suzuki , Takamitsu Hosoya
IPC分类号： A01N61/00 , A61K31/00 , A61K49/00 , C12N15/09 , C12N9/12
CPC分类号： A61K31/444 , A61K31/4409 , A61K31/4439 , A61K31/4453 , A61K31/4545 , A61K31/455 , A61K31/5377 , A61K31/55 , C07D211/14 , C07D213/81 , C07D213/82 , C07D401/12 , C12N15/1137 , Y02A50/385 , Y02A50/389 , Y02A50/463 , Y02A50/465 , Y02A50/467
摘要： The present invention provides: (1) antiviral agents that act by reducing or inhibiting the activity of SR proteins, more specifically, (i) antiviral agents that act by enhancing dephosphorylation of SR proteins, and (ii) antiviral agents that act by inhibiting proteins that phosphorylate SR proteins; (2) antiviral agents that act by inhibiting the expression of SR proteins, and (3) antiviral agents that act by activating proteins that antagonize SR proteins. The present invention also provides compounds that inhibit SRPKs, which phosphorylate SR proteins. Such compounds inhibit the activity of SR proteins and have antiviral activities. Various new viruses including SARS have emerged, and thus the present invention provides long-lasting broad-spectrum antiviral agents applicable to new viruses.
摘要翻译：本发明提供：（1）通过降低或抑制SR蛋白的活性而起作用的抗病毒剂，更具体地，（i）通过增强SR蛋白的去磷酸化作用的抗病毒剂，和（ii）通过抑制蛋白质起作用的抗病毒剂磷酸化SR蛋白; （2）通过抑制SR蛋白的表达起作用的抗病毒剂，和（3）通过激活拮抗SR蛋白的蛋白质起作用的抗病毒剂。本发明还提供抑制磷酸化SR蛋白的SRPK的化合物。这些化合物抑制SR蛋白的活性并具有抗病毒活性。出现了包括SARS在内的各种新病毒，因此本发明提供了适用于新病毒的长效广谱抗病毒剂。

48. 发明申请

US20120243401A1 TERMINAL DEVICE AND COMMUNICATION METHOD 审中-公开
标题翻译：终端设备和通信方法
公开(公告)号：US20120243401A1
公开(公告)日：2012-09-27
申请号：US13498716
申请日：2010-09-28
申请人： Hiromi Himeno , Masashi Kanauchi , Takehiro Ida , Masaaki Suzuki , Taketoshi Nakajima
发明人： Hiromi Himeno , Masashi Kanauchi , Takehiro Ida , Masaaki Suzuki , Taketoshi Nakajima
IPC分类号： H04W76/06
CPC分类号： H04W88/02 , H04W76/10 , H04W76/30
摘要： A terminal device (100) is provided with a C-PLANE processing unit (131) which sets an RRC connection between the terminal device and a radio station (200), and sets an RAB and a PDP context between the terminal device and a network (300), and a U-PLANE processing unit (132) which performs processing for transmitting user data using the PDP context set by the C-PLANE processing unit (131). The C-PLANE processing unit (131) performs local release for releasing the PDP context in the terminal device when the transmission of the user data has failed in a preservation state.
摘要翻译：终端装置（100）具备设置终端装置与无线电台（200）之间的RRC连接的C-PLANE处理部（131），并在终端装置与网络之间设定RAB和PDP上下文（300）以及使用由C-PLANE处理单元（131）设置的PDP上下文来发送用户数据的处理的U-PLANE处理单元（132）。当在保存状态下用户数据的传输失败时，C-PLANE处理单元（131）执行本地释放以释放终端设备中的PDP上下文。

49. 发明申请

US20120128588A1 ISOTOPE LABELED 2-ARYLPROPIONIC ACID COMPOUNDS AND PROCESS FOR PRODUCTION OF SAME, AND MOLECULAR PROBE FOR POSITRON EMISSION TOMOGRAPHY AND METHOD FOR IMAGING OF CYCLOOXYGENASE AND THE LIKE USING SAME 失效
标题翻译：同位素标记的2-芳基丙酸化合物及其生产方法，以及用于排放反应的分子探针和用于形成环糊精和类似物的方法
公开(公告)号：US20120128588A1
公开(公告)日：2012-05-24
申请号：US13387753
申请日：2010-07-29
申请人： Misato Takashima , Miho Shukuri , Miki Goto , Hisashi Doi , Hirotaka Onoe , Masaaki Suzuki , Yasuyoshi Watanabe
发明人： Misato Takashima , Miho Shukuri , Miki Goto , Hisashi Doi , Hirotaka Onoe , Masaaki Suzuki , Yasuyoshi Watanabe
IPC分类号： A61K51/04 , C07C69/612 , C07C57/30 , C07C69/616
CPC分类号： A61K31/192 , A61K49/0433 , A61K51/04 , A61K51/0402 , C07B59/001 , C07B2200/05 , C07B2200/07 , C07C57/30 , C07C57/58 , C07C59/64 , C07C59/68 , C07C59/84 , C07C59/86 , C07C69/612 , C07C69/65 , C07C69/734 , C07C69/736 , C07C69/738 , C07C2601/08
摘要： Disclosed are: labeled NSAIDs compounds which can be produced within a short time, can be used suitably for a PET method, and enable the imaging of cyclooxygenase-2; and a process for producing the labeled NSAIDs compounds. Specifically disclosed are isotope-labeled 2-arylpropionic acid compounds, each of which is a compound represented by general formula (1) (wherein Ar represents an aryl group which may have a substituent; R1 represents anyone selected from 11CH3, CH218F and CF218F; and R2 represents a hydrogen atom, or an alkyl group which may have a branch, wherein a compound wherein Ar is a benzene ring, R1 is 11CH3, and R2 is a hydrogen atom is excluded), or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof.
摘要翻译：公开的是：可以在短时间内生产的标记的NSAIDs化合物可以适用于PET方法，并且能够进行环氧合酶-2的成像; 以及生产标记的NSAIDs化合物的方法。具体公开的是同位素标记的2-芳基丙酸化合物，其各自为通式（1）表示的化合物（其中Ar表示可具有取代基的芳基; R1表示选自11CH3，CH218F和CF218F的任何一种; R2表示氢原子或可具有支链的烷基，其中Ar为苯环，R1为11CH3，R2为氢原子的化合物除外），或其药学上可接受的盐，水合物，溶剂合物或前药。

50. 发明申请

US20120112037A1 THREE-DIMENSIONAL IMAGING DEVICE 审中-公开
标题翻译：三维成像装置
公开(公告)号：US20120112037A1
公开(公告)日：2012-05-10
申请号：US13382183
申请日：2011-02-10
申请人： Masao Hiramoto , Masayuki Misaki , Teruyuki Takazawa , Masaaki Suzuki
发明人： Masao Hiramoto , Masayuki Misaki , Teruyuki Takazawa , Masaaki Suzuki
IPC分类号： H01J40/14
CPC分类号： G03B35/08 , H04N13/204 , H04N13/211 , H04N13/218
摘要： An image capture device according to the present invention includes an imaging lens 3, a light-transmitting section 2 with two polarizers, a rotation driving section 2A that rotates the light transmitting section 2, and a solid-state image sensor 1 that has multiple pixels and their associated polarization filters. A first polarization filter 50a is arranged to face a first group of pixels W1 and a second polarization filter 50b is arranged to face a second group of pixels W2. The respective transmission axes of the polarizing areas P(1) and P(2) of the light-transmitting section 2 form an angle α between themselves. Also, the respective transmission axes of the polarization filters 50a and 50b form an angle β between themselves. And the rotation driving section 2A can rotate the light-transmitting plate 2 on the optical axis. As a result, multiple sets of multi-viewpoint images can be obtained.
摘要翻译：根据本发明的图像捕获装置包括成像透镜3，具有两个偏振器的透光部分2，旋转光发射部分2的旋转驱动部分2A和具有多个像素的固态图像传感器1 及其相关的偏振滤光片。第一偏振滤光器50a布置成面对第一组像素W1，并且第二偏振滤光器50b布置成面对第二组像素W2。透光部分2的偏振光P（1）和P（2）的透射轴各自在它们之间形成角度α。此外，偏振光滤光器50a和50b的各个透射轴形成角度＆amp; bgr; 在他们之间并且旋转驱动部2A能够使透光板2在光轴上旋转。结果，可以获得多组多视点图像。

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