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41. 发明授权

US5990161A Hydroximic acid derivatives 失效
标题翻译：羟基亚氨酸衍生物
公开(公告)号：US5990161A
公开(公告)日：1999-11-23
申请号：US222870
申请日：1998-12-30
申请人： Yoshie Kirio , Takako Maeda , Norio Sasaki , Norishige Toshima , Nobumitsu Sawai , Bruce Milligan , Joseph Perez , Jean-Pierre Vors , Daniel B. Gant
发明人： Yoshie Kirio , Takako Maeda , Norio Sasaki , Norishige Toshima , Nobumitsu Sawai , Bruce Milligan , Joseph Perez , Jean-Pierre Vors , Daniel B. Gant
IPC分类号： C07D239/34 , A01N37/36 , A01N37/52 , C07C20060101 , C07C251/10 , C07C259/06 , C07C259/08 , C07C259/10 , C07C317/28 , C07C327/58 , C07C327/60 , C07C333/12 , C07C335/40 , A01N33/24 , C07C251/26
CPC分类号： A01N37/52 , C07C259/06 , C07C259/08 , C07C259/10 , C07C327/58 , C07C327/60
摘要： Hydroximic acid derivatives, useful as pesticides, have the formula ##STR1## in which G is G.sub.3 or G.sub.4 having the formula: ##STR2## in which R.sub.5 is lower alkyl; R.sub.6 and R.sub.7 are, independently, hydrogen or lower alkyl; W is O, S, SO or SO.sub.2 ; X.sub.1, X.sub.2 and X.sub.3 are, independently, hydrogen or a variety of substituents; and R.sub.1, R.sub.2 and R.sub.3 are, independently, hydrogen or a variety of substituents.
摘要翻译：可用作农药的羟基亚氨酸衍生物具有下列通式：其中G为具有下式的G 3或G 4：其中R 5为低级烷基; R6和R7独立地是氢或低级烷基; W是O，S，SO或SO2; X1，X2和X3独立地是氢或各种取代基; 且R 1，R 2和R 3独立地为氢或各种取代基。

42. 发明授权

US5948805A Fungicidal mixtures 失效
标题翻译：杀菌混合物
公开(公告)号：US5948805A
公开(公告)日：1999-09-07
申请号：US981999
申请日：1998-01-09
申请人： Ray M. Geddens , Marsha J. Martin
发明人： Ray M. Geddens , Marsha J. Martin
IPC分类号： A01N43/76 , A01N47/34 , A01P3/00 , A01N37/34 , A01N37/52
CPC分类号： A01N43/76 , A01N47/34
摘要： Advantageous combinations of an oxazolidinone and cymoxanil (or their agriculturally suitable salts) and their use to control fungus disease in plants are disclosed, the oxazolidinone having the formula ##STR1##
摘要翻译： PCT No.PCT / US96 / 11346 Sec。 371日期1997年1月9日 102（e）1997年1月9日PCT PCT 1996年7月3日PCT公布。公开号WO97 / 02745 日期1997年1月30日公开了恶唑烷酮和cymoxanil（或其农业上合适的盐）的有利组合及其在植物中控制真菌病的用途，具有式

43. 发明授权

US5942538A Benzamidoxime derivatives, method for preparation thereof and fungicide for agricultural and horticultural use 失效
标题翻译：苯甲脒衍生物，其制备方法和用于农业和园艺用途的杀真菌剂
公开(公告)号：US5942538A
公开(公告)日：1999-08-24
申请号：US104540
申请日：1998-06-26
申请人： Isamu Kasahara , Hirohito Ooka , Shinsuke Sano , Hiroyasu Hosokawa , Homare Yamanaka
发明人： Isamu Kasahara , Hirohito Ooka , Shinsuke Sano , Hiroyasu Hosokawa , Homare Yamanaka
IPC分类号： A01N37/52 , A01N43/10 , A01N43/36 , A01N43/56 , A01N43/58 , C07C259/18 , C07C317/18 , C07C317/22 , C07C317/44 , C07C319/20 , C07C323/12 , C07C323/60 , C07C323/62 , C07D207/337 , C07D231/12 , C07D333/24 , C07D521/00 , C07D207/30
CPC分类号： A01N37/52 , A01N43/10 , A01N43/56 , C07C259/18 , C07C317/18 , C07C317/22 , C07C317/44 , C07C323/12 , C07C323/60 , C07C323/62 , C07D231/12 , C07D233/56 , C07D249/08 , C07D333/24 , C07C2101/02 , C07C2101/08 , C07C2101/14 , C07C2101/16
摘要： The present invention relates to benzamidoxime derivatives represented by the formula �I!; ##STR1## wherein R.sup.1 is unsubstituted or substituted C.sub.1 -C.sub.4 alkyl, unsubstituted or substituted C.sub.2 -C.sub.4 alkenyl or unsubstituted or substituted C.sub.2 -C.sub.4 alkynyl, R.sup.2 is phenyl optionally having substituents or heterocycle optionally having substituents X.sup.1, X.sup.2, X.sup.3 and X.sup.4 are each independently hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 alkylthio or the like, and r.sub.1 and r.sub.2 are each independently hydrogen, C.sub.1 -C.sub.4 alkyl or the like, having excellent fungicidal activity and being useful as a fungicide for agricultural and horticultural use, and methods for preparation thereof.
摘要翻译：本发明涉及由式[I]表示的苯甲酰胺肟衍生物。其中R1是未取代的或取代的C1-C4烷基，未取代或取代的C2-C4烯基或未取代或取代的C2-C4炔基，R2是任选具有取代基的苯基或任选具有取代基X1，X2，X3和X4的杂环各自独立地为氢，卤素，C1-C4烷基，C1-C4卤代烷基，C1-C4烷氧基，C1-C4卤代烷氧基，C1-C4烷硫基等，并且r1和r2各自独立地为氢，C1-C4烷基等，具有优异的杀真菌性活性和用作农业和园艺用途的杀真菌剂及其制备方法。

44. 发明授权

US5942218A Anti-infective material 失效
标题翻译：抗感染材料
公开(公告)号：US5942218A
公开(公告)日：1999-08-24
申请号：US955132
申请日：1997-10-21
申请人： Ulrich Kirschner , Frank Jethon , Frank Rauch
发明人： Ulrich Kirschner , Frank Jethon , Frank Rauch
IPC分类号： A61K31/785 , A01N47/44 , A61K31/155 , A61L12/14 , A61P31/04 , A61P31/12 , A61P33/10 , A61K31/74 , A01N37/52
CPC分类号： A01N47/44 , A61K31/155 , A61L12/142
摘要： The subject matter comprises anti-infective materials such as antimicrobial materials based upon poly(hexamethylene)biguanide having a weight proportion of said polymer containing 5 or less units per chain is less than 2% based on entire polymer weight, which are suitably in the form of a wound antiseptic and/or a wound treating material or a material for anti-microbial, antiviral, and/or antiparasitic treatment which may suitably be administered by the intravenous mode. The utilization concentration of the poly(hexamethylene)biguanide as a wound antiseptic and/or a wound treatment material suitably lies in the range of 0.001 through 0.05 wt. %, in particular 0.005 through 0.012 wt. %. As compared to the known disinfective materials based upon poly(hexamethylene)biguanide which have been utilized as wound antiseptics and wound treatment materials, the poly-(hexamethylene)biguanides utilized in the present invention have a higher mean molecular weight and demonstrate an increased microbicidal activity coupled with lower toxicity and are free of side effects on the central nervous system.
摘要翻译：主题包括抗感染材料，例如基于聚（六亚甲基）双胍的抗微生物材料，其具有所述聚合物的重量比例，每个链含有5个或更少个单元，基于整个聚合物重量小于2％，其适当形式为的伤口防腐剂和/或伤口处理材料或抗微生物，抗病毒和/或抗寄生虫治疗的材料，其可以通过静脉内模式适当地施用。作为伤口防腐剂和/或伤口处理材料的聚（六亚甲基）双胍的利用浓度适当地在0.001〜0.05重量％的范围内。％，特别是0.005〜0.012wt。％。与已经用作伤口防腐剂和伤口处理材料的基于聚（六亚甲基）双胍的已知消毒材料相比，本发明中使用的聚（六亚甲基）双胍具有较高的平均分子量，并表现出增加的杀微生物活性加上较低的毒性，对中枢神经系统无副作用。

45. 发明授权

US5563168A O-Benzyloxime ethers and crop protection agents containing these compounds 失效
标题翻译： O-苄氧基肟醚和含有这些化合物的作物保护剂
公开(公告)号：US5563168A
公开(公告)日：1996-10-08
申请号：US490895
申请日：1995-06-16
申请人： Siegbert Brand , Uwe Kardorff , Reinhard Kirstgen , Bernd Mueller , Klaus Oberdorf , Hubert Sauter , Gisela Lorenz , Eberhard Ammermann , Christoph Kuenast , Albrecht Harreus
发明人： Siegbert Brand , Uwe Kardorff , Reinhard Kirstgen , Bernd Mueller , Klaus Oberdorf , Hubert Sauter , Gisela Lorenz , Eberhard Ammermann , Christoph Kuenast , Albrecht Harreus
IPC分类号： C07C251/60 , A01N37/32 , A01N37/34 , A01N37/36 , A01N37/38 , A01N37/42 , A01N37/44 , A01N37/50 , A01N37/52 , A01N43/00 , A01N43/16 , C07C255/64 , C07C257/06 , C07C323/47 , C07C323/50 , C07C323/56 , C07C323/60 , C07C327/22 , C07D209/48 , C07D309/04 , C07D309/12 , C07D309/28 , C07D401/04 , C07D401/12 , A01N43/40 , C07D213/55 , C07D309/06
CPC分类号： C07D209/48 , A01N37/36 , A01N37/38 , A01N37/50 , A01N43/16 , C07C251/60 , C07C255/64 , C07C257/06 , C07C323/47 , C07C323/56 , C07C323/60 , C07C327/22 , C07D309/04 , C07D309/12 , C07C2101/02 , C07C2101/04 , C07C2101/08 , C07C2101/14
摘要： O-Benzyloxime ethers of the formula I ##STR1## where 5 X is substituted or unsubstituted CH.sub.2, NOalkylY isO, S, NR.sup.5R.sup.1, R.sup.2, R.sup.5 are H, alkylZ.sup.1, Z.sup.2 are H, halogen, methyl, methoxy, cyanoR.sup.3, R.sup.4 are hydrogen, cyano, substituted or unsubstituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkynyl, alkoxy, haloalkoxy, alkylthio, benzylthio, alkylcarbonyl, substituted or unsubstituted phenylcarbonyl, substituted or unsubstituted benzylcarbonyl, alkoxycarbonyl, substituted or unsubstituted phenoxycarbonyl, substituted or unsubstituted benzyloxycarbonyl,N(R.sup.6).sub.2, where R.sup.6 is H, alkyl, substituted or unsubstituted phenyl,--CO--N(R.sup.7).sub.2, where R.sup.7 is H, substituted or unsubstituted alkyl,substituted or unsubstituted aryl, substituted or unsubstituted aryloxy, substituted or unsubstituted arylthio, substituted or unsubstituted hetaryl, substituted or unsubstituted hetaryloxy, substituted or unsubstituted hetarylthio, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heterocyclyloxy,R.sup.3 and R.sup.4 together may form a carbocyclic or heterocyclic ring which is substituted or unsubstituted, andR.sup.3 or R.sup.4 may be halogen, or ##STR2## may be ##STR3## where n is an integer from 1 to 4, andR.sup.8 is, or, when n>1, the R.sup.8' s are identical or different and are each, H, halogen, cyano, nitro or substituted or unsubstituted C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -haloalkyl, C.sub.1 -C.sub.4 -haloalkoxy, aryl, aryloxy, benzyloxy, hetaryl or hetaryloxy.and crop protection agents containing these compounds.
摘要翻译：式I的O-苄氧基肟其中5 X是取代或未取代的CH 2，NO 2烷基Y是O，S，NR 5 R 1，R 2，R 5是H，烷基Z 1，Z 2是H，卤素，甲基，甲氧基，氰基R3，R4是氢，氰基，取代或未取代的烷基，烯基，环烷基，环烯基，炔基，烷氧基，卤代烷氧基，烷硫基，苄硫基，烷基羰基，取代或未取代的苯基羰基，取代或未取代的苄基羰基，烷氧基羰基，取代或未取代的苯氧基羰基取代或未取代的苄氧基羰基，N（R6）2，其中R6是H，烷基，取代或未取代的苯基，-CO-N（R7）2，其中R7是H，取代或未取代的烷基，取代或未取代的芳基，未取代的芳氧基，取代或未取代的芳硫基，取代或未取代的杂芳基，取代或未取代的杂芳氧基，取代或未取代的杂芳硫基，取代或未取代的杂环基， R 3和R 4一起可以形成被取代或未取代的碳环或杂环，并且R 3或R 4可以是卤素，或者可以是，其中n是1至4的整数，并且R 8是，或者当n> 1时，R 8相同或不同，各自为H，卤素，氰基，硝基或取代或未取代的C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基，C 1 -C 4 - 卤代烷基，C 1 -C 4 - 卤代烷氧基，芳基，芳氧基，苄氧基，杂芳基或杂芳基氧基。和含有这些化合物的作物保护剂。

46. 发明授权

US5554619A Microbicides 失效
标题翻译：杀菌剂
公开(公告)号：US5554619A
公开(公告)日：1996-09-10
申请号：US424683
申请日：1995-04-18
申请人： Ronald Zeun , Ren e Zurfl uh
发明人： Ronald Zeun , Ren e Zurfl uh
IPC分类号： A01N37/52 , A01N43/54 , A01N37/12 , A01N37/44
CPC分类号： A01N43/54
摘要： Microbicidal composition for use in plants, having a synergistic action and comprising at least two active ingredient components, in which component I is a compound selected from the group of the compounds ##STR1## in which: X is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, trifluoromethyl, cyano, thiocarbamoyl or nitro, andY is hydrogen or fluorine; ##STR2## in which: Z radicals are identical or different and are halogen, cyano, nitro, C.sub.1 -C.sub.4 alkyl,C.sub.1 -C.sub.4 alkoxy, trifluoromethyl, phenyl, phenoxy or benzyl, these aromatic groups being unsubstituted or not more than trisubstituted by identical or different substituents from the series comprising halogen, cyano, nitro, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or trifluoromethyl, and n is 0 to 3; and ##STR3## in which: U is oxygen or the group --CH.sub.2 O--,A radicals are identical or different and are halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or trifluoromethyl, andn is 0 to 3;and in which component II is the 2-anilinopyrimidine of the formula II ##STR4## 4-cyclopropyl-6-methyl-N-phenyl-2-pyrimidineamine or a salt or a metal complex thereof.
摘要翻译：用于植物的具有协同作用并且包含至少两种活性成分组分的杀微生物组合物，其中组分I是选自化合物1A的化合物，其中：X是氢，卤素，C 1 -C 4烷基，C 1 -C 4烷氧基，三氟甲基，氰基，硫代氨基甲酰基或硝基，Y是氢或氟; 其中：Z基团相同或不同，为卤素，氰基，硝基，C 1 -C 4烷基，C 1 -C 4烷氧基，三氟甲基，苯基，苯氧基或苄基，这些芳基为未取代或不多于被相同或不同包含卤素，氰基，硝基，C 1 -C 4烷基，C 1 -C 4烷氧基或三氟甲基的不同取代基，n为0-3; 和其中：U是氧或基团-CH 2 O-，A基团相同或不同，并且是卤素，C 1 -C 4烷基，C 1 -C 4烷氧基或三氟甲基，n是0至3; 并且其中组分II是式II的吡啶并嘧啶或其盐或其金属络合物。

47. 发明授权

US5545664A Substituted phenoxymethylphenyl derivatives, their preparation and their use for controlling pests and fungi 失效
标题翻译：取代的苯氧基甲基苯基衍生物，其制备及其用于防治害虫和真菌的用途
公开(公告)号：US5545664A
公开(公告)日：1996-08-13
申请号：US409039
申请日：1995-03-23
申请人： Reinhard Kirstgen , Klaus Oberdorf , Hubert Sauter , Herbert Bayer , Wassilios Grammenos , Harald Rang , Volker Harries , Gisela Lorenz , Eberhard Ammermann
发明人： Reinhard Kirstgen , Klaus Oberdorf , Hubert Sauter , Herbert Bayer , Wassilios Grammenos , Harald Rang , Volker Harries , Gisela Lorenz , Eberhard Ammermann
IPC分类号： A01N37/38 , A01N37/50 , A01N37/52 , C07C251/48 , C07C251/50 , C07C255/62 , C07C255/64 , C07C259/02 , C07C259/10 , C07C259/18 , C07C323/47 , C07C327/58 , C07D317/18 , C07D333/28 , C07D521/00 , A01N37/34 , A61K31/275
CPC分类号： C07D231/12 , A01N37/50 , A01N37/52 , C07C251/48 , C07C255/64 , C07C259/02 , C07C259/10 , C07C259/18 , C07C327/58 , C07D233/56 , C07D249/08 , C07D317/18 , C07D333/28 , C07C2101/02 , C07C2101/08
摘要： Substituted phenoxymethylphenyl derivatives I ##STR1## X is .dbd.CH--OCH.sub.3, .dbd.C--CH.sub.3 or .dbd.N--OCH.sub.3 ; R.sup.1 is, inter alia,R.sup.2 and R.sup.3 are, inter alia,H, halogen, CN, NO.sub.2, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.2 -haloalkyl, C.sub.1 -C.sub.4 -alkoxy or C.sub.1 --C.sub.2 -haloalkoxy;R.sup.4 is, inter alia,CN, Cl, Dr, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.6 -alkylthio or C.sub.1 -C.sub.4 -haloalkoxy;R.sup.5 is, inter alia,NO.sub.2, CN, halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -haloalkyl, C.sub.1 -C.sub.4 -alkoxy or C.sub.1 -C.sub.4 -haloalkoxy;n is 0-4; Y is --O--, --NH--, --N(CH.sub.3)--; R.sup.6 is H, C.sub.1 -C.sub.4 -alkyl.The compounds are useful for controlling pests and fungi.
摘要翻译：取代的苯氧基甲基苯基衍生物I X为= CH-OCH 3，= C-CH 3或= N-OCH 3; R1尤其是R2和R3尤其是H，卤素，CN，NO2，C1-C4-烷基，C1-C2-卤代烷基，C1-C4-烷氧基或C1-C2-卤代烷氧基; R4尤其是CN，Cl，Dr，C 1 -C 6 - 烷氧基，C 1 -C 6 - 烷硫基或C 1 -C 4 - 卤代烷氧基; R5尤其是NO 2，CN，卤素，C 1 -C 4烷基，C 1 -C 4卤代烷基，C 1 -C 4 - 烷氧基或C 1 -C 4 - 卤代烷氧基; n为0-4; Y是-O - ， - NH - ， - N（CH 3） - ; R6是H，C1-C4-烷基。这些化合物可用于防治害虫和真菌。

48. 发明授权

US5508250A Synergistic antimicrobial compositions containing poly(hexamethylammonium) chloride. 失效
标题翻译：含有聚（六甲基铵）氯化物的协同抗菌组合物。
公开(公告)号：US5508250A
公开(公告)日：1996-04-16
申请号：US163118
申请日：1993-12-07
申请人： James J. Miller , Geoffrey A. Brown , E. LeRoy Lines
发明人： James J. Miller , Geoffrey A. Brown , E. LeRoy Lines
IPC分类号： A01N33/12 , C02F1/50 , A01N33/00 , A01N35/00 , A01N37/52
CPC分类号： C02F1/50 , A01N33/12 , C02F2103/42
摘要： Methods for inhibiting microbial growth in aqueous systems by the use of synergistic mixtures comprising poly(hexamethylammonium) chloride and at least one compound selected from the group consisting of poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene hydrochloride ("PHMB"), dodecylguanidine hydrochloride ("DGH") and poly[oxyethylene (dimethylimino) ethylene-(dimethylimino) ethylene dichloride] ("PDED"). Antimicrobial compositions comprising the synergistic mixture and a carrier are also disclosed.
摘要翻译：通过使用包含聚（六甲基铵）氯化物和至少一种选自聚亚氨基亚氨基亚氨基亚氨基亚氨基亚氨基亚氨基亚氨基亚氨基六亚甲基盐酸盐（“PHMB”），十二烷基胍盐酸盐（“DGH”）和聚 [氧乙烯（二甲基亚氨基）乙烯 - （二甲基亚氨基）二氯乙烯]（“PDED”）。还公开了包含协同混合物和载体的抗微生物组合物。

49. 发明授权

US5449803A Oxime ether compound, processes for preparing the same and fungicide containing the same 失效
标题翻译：肟醚化合物，其制备方法和含有它们的杀真菌剂
公开(公告)号：US5449803A
公开(公告)日：1995-09-12
申请号：US214188
申请日：1994-03-17
申请人： Masanori Watanabe , Toshinobu Tanaka , Shuji Yokoyama , Hideaki Umeyama , Tadashi Murakami
发明人： Masanori Watanabe , Toshinobu Tanaka , Shuji Yokoyama , Hideaki Umeyama , Tadashi Murakami
IPC分类号： A01N37/52 , A01N53/00 , C07C327/58 , C07C321/10
CPC分类号： C07C327/58 , A01N37/52 , A01N53/00 , C07C2101/02 , C07C2101/04
摘要： Disclosed are an oxime ether compound represented by the formula (I): ##STR1## wherein R.sup.1 represents an alkyl group having 1 to 6 carbon atoms; R.sup.2 represents OR.sup.5 or NHR.sup.6 where R.sup.5 and R.sup.6 each represent an alkyl group having 1 to 6 carbon atoms; R.sup.3 represents a cycloalkyl group having 3 to 8 carbon atoms; R.sup.4 represents an alkenyloxy group having 3 to 6 carbon atoms, an alkynyloxy group having 3 to 6 carbon atoms, an alkoxy group having 1 to 10 carbon atoms, a benzyloxy group, an alkoxycarbonyl group having 2 to 7 carbon atoms, a halogen atom, a cyano group, an alkylthio group having 1 to 6 carbon atoms, an alkyl group having 1 to 6 carbon atoms, a haloalkyl group having 1 to 6 carbon atoms or an acyl group having 2 to 7 carbon atoms; and n represents an integer of 0 to 5.processes for preparing the same and a fungicide containing the same as an effective ingredient.
摘要翻译：公开了由式（I）表示的肟醚化合物：其中R 1表示具有1至6个碳原子的烷基; R 2表示OR 5或NHR 6，其中R 5和R 6各自表示具有1至6个碳原子的烷基; R3代表具有3-8个碳原子的环烷基; R4表示碳原子数3〜6的烯氧基，碳原子数3〜6的炔氧基，碳原子数1〜10的烷氧基，苄氧基，碳原子数2〜7的烷氧基羰基，卤素原子，氰基，碳原子数1〜6的烷硫基，碳原子数1〜6的烷基，碳原子数1〜6的卤代烷基或碳原子数2〜7的酰基。 n表示0〜5的整数。其制备方法和含有该有效成分的杀真菌剂。

50. 发明授权

US5420350A Bis-biguanide compound useful as a disinfectant 失效
标题翻译：双胍类化合物可用作消毒剂
公开(公告)号：US5420350A
公开(公告)日：1995-05-30
申请号：US298300
申请日：1994-09-01
申请人： Akira Nishihara , Akihiro Nakamura , Tsunetoshi Honda , Michio Harada , Maki Takizawa
发明人： Akira Nishihara , Akihiro Nakamura , Tsunetoshi Honda , Michio Harada , Maki Takizawa
IPC分类号： A01N47/44 , A61K31/155 , A61P31/04 , C07C279/26 , C07C279/06 , A01N37/52 , C07C279/18
CPC分类号： C07C279/265
摘要： A novel bis-biguanide compound suitable for use as a disinfectant has the following formula: ##STR1## where n is an integer from 2 to 10 inclusive. A pharmaceutically acceptable salt, particularly gluconate salt of the compound is also useful as a disinfectant. The bis-biguanide compound has germicidal activities comparable to those of widely used chlorhexidine with respect to width of antibacterial spectrum and is superior to chlorhexidine in immediate effectiveness. It exhibits excellent germicidal activities against Pyocyaneus bacilli, on which chlorhexidine has poor effect.
摘要翻译：适合用作消毒剂的新型双双胍化合物具有以下分子式：其中n为2至10的整数，包括端值。化合物的药学上可接受的盐，特别是葡萄糖酸盐也可用作消毒剂。双胍类化合物具有与广泛使用的氯己定相比具有抗菌谱宽度的杀菌活性，并且立即有效地优于氯己定。它对抗疟原菌显示出优异的杀菌活性，氯己定对其效果不佳。

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