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1. 发明申请

US20230024283A1 HERBICIDAL COMPOUNDS 有权
公开(公告)号：US20230024283A1
公开(公告)日：2023-01-26
申请号：US17790080
申请日：2020-12-24
申请人： SYNGENTA CROP PROTECTION AG
发明人： James Alan MORRIS , Katharine Mary INGRAM , Suzanna Jane DALE , David BURNS
IPC分类号： C07D231/12 , C07D213/84 , C07C255/55 , C07D277/587 , C07C255/53 , C07D271/06 , C07D239/26 , C07D213/64 , C07D213/57 , C07C323/31 , C07D491/056 , C07D317/60 , C07C317/14 , C07D213/71 , C07D333/24 , C07D213/69 , C07D333/28 , C07D249/08 , C07D275/02 , C07D263/32 , C07D241/12 , C07D237/08 , C07D285/08 , C07D307/54 , C07D249/06 , A01P13/00 , A01N43/56 , A01N43/40 , A01N37/34 , A01N43/78 , A01N43/82 , A01N43/54 , A01N43/90 , A01N43/30 , A01N37/52 , A01N43/10 , A01N43/653 , A01N43/76 , A01N43/80 , A01N43/60 , A01N43/58 , A01N43/647 , A01N43/08
摘要： The present invention relates to compounds of Formula (I), or an agronomically acceptable salt of said compounds wherein R1, R2, R3 and R4 are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling weeds, in particular in crops of useful plants.

2. 发明申请

US20220290072A1 CONTACT LENS TREATING SOLUTION 有权
公开(公告)号：US20220290072A1
公开(公告)日：2022-09-15
申请号：US17691260
申请日：2022-03-10
申请人： Bausch + Lomb Ireland Limited
发明人： Vicki Barniak , Catherine Scheuer , William T. Reindel , John Michael Duex , Andrea E. Giallombardo
IPC分类号： C11D3/00 , A01N33/12 , A01N37/52 , A01P1/00 , C11D1/722 , C11D3/22 , C11D3/20 , C11D3/04 , C11D3/48 , A61L12/14
摘要： A contact lens treating solution includes (a) about 0.005 to about 2 wt. %, based on the total weight of the contact lens treating solution, of hyaluronic acid or a salt thereof; (b) about 0.01 to about 1 wt. %, based on the total weight of the contact lens treating solution, of erythritol; (c) one or more nonionic surfactants; (d) sodium chloride, potassium chloride or any combination thereof; and (e) one or more buffers.

3. 发明申请

US20200253846A1 ANTIMICROBIAL MIXTURE CONTAINING 4-(3-ETHOXY-4-HYDROXYPHENYL) BUTAN-2-ONE, AND COSMETIC COMPOSITION CONTAINING SAME 审中-公开
公开(公告)号：US20200253846A1
公开(公告)日：2020-08-13
申请号：US16626089
申请日：2018-06-27
申请人： L'OREAL
发明人： Florence MENARD-SZCZEBARA , Sylvie CUPFERMAN , Gael MALET , Julien GALVAN
IPC分类号： A61K8/35 , A01N35/02 , A01N43/40 , A01N59/16 , A61K8/49 , A61Q19/10 , A61Q17/04 , A01N43/50 , A01N37/52 , A61K8/40 , A61Q1/00
摘要： The invention relates to an antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an additional compound chosen from a monovalent or divalent metal salt of pyrithione, piroctone olamine, diazolidinylurea, a hexamidine compound, and imidazolidinylurea,and also to a cosmetic composition containing such a mixture.Application to caring for, making up and cleansing keratin materials.

4. 发明授权

US10252977B2 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides 有权
公开(公告)号：US10252977B2
公开(公告)日：2019-04-09
申请号：US15736242
申请日：2016-06-10
申请人： Bayer Cropscience Aktiengesellschaft
发明人： Stefan Hillebrand , Mazen Es-Sayed , Joerg Greul , Ulrike Wachendorff-Neumann , Juergen Benting , Stephane Brunet
IPC分类号： C07C205/38 , C07C257/12 , C07C217/90 , A01N37/52
摘要： The present invention relates to halogen-substituted phenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to an agrochemical formulation for this purpose, comprising the halogen-substituted phenoxyphenylamidines according to the invention. Furthermore, the invention relates to a method for controlling unwanted microorganisms by applying the compounds according to the invention to the microorganisms and/or their habitat.

5. 发明申请

US20160113317A1 COMPOSITIONS, METHODS, AND KITS FOR REGULATING ENERGY METABOLISM 有权
公开(公告)号：US20160113317A1
公开(公告)日：2016-04-28
申请号：US14927228
申请日：2015-10-29
申请人： NuSirt Sciences, Inc.
发明人： Michael Zemel , E. Douglas Grindstaff, II
IPC分类号： A01N37/52 , A61K31/155
CPC分类号： A61K31/4415 , A23L33/15 , A23L33/175 , A23V2002/00 , A61K31/155 , A61K31/191 , A61K31/194 , A61K31/198 , A23V2200/332 , A23V2250/0628 , A23V2250/7052 , A61K2300/00
摘要： The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.

6. 发明授权

US08815952B1 Chlorhexadine antiseptic 有权
标题翻译：氯己定防腐剂
公开(公告)号：US08815952B1
公开(公告)日：2014-08-26
申请号：US13843391
申请日：2013-03-15
申请人： Carnell & Herzog, LLC
发明人： Victor Carnell , Chris Herzog
IPC分类号： A01N37/52 , A61K31/155 , A61K31/4425 , A61K31/198
CPC分类号： A61K31/155 , A01N43/40 , A01N47/44 , A61K8/43 , A61K8/44 , A61K8/4926 , A61K31/198 , A61K31/4425 , A61Q17/005 , A61Q19/10 , A01N37/30 , A01N2300/00
摘要： A composition comprising a mixture of chlorohexidine, a surfactant, and a cationic quaternary ammonium compound is suitable for use as an antiseptic and is surprisingly effective against difficult-to-kill organisms such as Mycobacterium tuberculosis and against Methicillin-resistant Staphylococcus aureus (MRSA) while still being suitable for topical application. The composition may include a chelating agent.
摘要翻译：包含氯己定，表面活性剂和阳离子季铵化合物的混合物的组合物适合用作防腐剂，并且对于难以杀死的生物例如结核分枝杆菌和耐甲氧西林金黄色葡萄球菌（MRSA）而言令人惊奇地有效，而仍适用于局部应用。组合物可以包括螯合剂。

7. 发明申请

US20130150451A1 BIOCIDAL COMPOSITIONS AND METHODS OF USING THE SAME 有权
标题翻译：生物组合物及其使用方法
公开(公告)号：US20130150451A1
公开(公告)日：2013-06-13
申请号：US13313880
申请日：2011-12-07
申请人： Joseph C. Salamone , Ann Beal Salamone
发明人： Joseph C. Salamone , Ann Beal Salamone
IPC分类号： A01N37/52 , A01P1/00
CPC分类号： A01N47/44 , A61K31/155 , Y02A50/473 , A01N31/02 , A01N37/12
摘要： An antimicrobial composition with synergistic biocidal activity is described which comprises at least one antimicrobial polymeric biguanide and at least one antimicrobial vicinal diol, said vicinal diol comprises at least one monoalkyl glycol, monoalkyl glycerol, or monoacyl glycerol, to diminish or eliminate biofilm communities. Such synergistic interaction is effective in wound treatment, particularly for chronic wounds, burns and battlefield-induced wounds, as well as for disinfecting non-biological surfaces. The antimicrobial composition can also be prepared as viscous solutions or as gels. The antimicrobial composition may be added to a substrate and dried, such as to a catheter, or to a foam, or to a fiber wound dressing, or coated as a viscous solution or gel upon such devices, to provide controlled release antimicrobial activity.
摘要翻译：描述了具有协同杀生物活性的抗微生物组合物，其包含至少一种抗微生物聚合双胍和至少一种抗微生物连位二醇，所述连位二醇包含至少一种单烷基二醇，单烷基甘油或单酰基甘油，以减少或消除生物膜群落。这种协同相互作用在伤口治疗中是有效的，特别是对于慢性伤口，烧伤和战场引起的伤口以及用于消毒非生物表面。抗微生物组合物也可以制备成粘稠溶液或凝胶。抗微生物组合物可以加入到基质中并干燥，例如导管，或泡沫，或纤维伤口敷料，或在这种装置上作为粘性溶液或凝胶涂覆，以提供受控释放的抗微生物活性。

8. 发明申请

US20130150392A1 IMINOPROPENE COMPOUND AND USE THEREOF 失效
标题翻译：亚硝基化合物及其用途
公开(公告)号：US20130150392A1
公开(公告)日：2013-06-13
申请号：US13762708
申请日：2013-02-08
申请人： SUMITOMO CHEMICAL COMPANY, LIMITED
发明人： Shigeyuki ITOH , Atsushi IWATA
IPC分类号： C07C323/45 , A01N43/90 , A01N43/42 , A01N43/82 , A01N43/78 , A01N43/76 , A01N43/653 , A01N37/52 , C07D239/42 , C07D471/04 , C07D215/58 , C07D271/10 , C07D277/64 , C07D263/32 , C07D249/02 , A01N43/54
CPC分类号： A01N37/52 , A01N37/36 , A01N37/38 , A01N43/40 , A01N43/42 , A01N43/50 , A01N43/54 , A01N43/653 , A01N43/76 , A01N43/78 , A01N43/82 , A01N43/90 , C07C255/61 , C07C317/40 , C07C323/45 , C07C323/60 , C07C327/58 , C07C2601/02 , C07C2601/14 , C07D213/61 , C07D213/70 , C07D213/75 , C07D215/58 , C07D233/84 , C07D239/38 , C07D239/42 , C07D249/02 , C07D249/10 , C07D257/04 , C07D263/32 , C07D263/58 , C07D271/10 , C07D277/36 , C07D277/64 , C07D277/74 , C07D307/64 , C07D333/20 , C07D333/28 , C07D403/04 , C07D471/04
摘要： The compound (I) or a salt thereof has an excellent controlling activity against pests. Then the compound (I) or a salt thereof is useful for an active ingredient of a pesticidal composition.
摘要翻译：化合物（I）或其盐对害虫具有优异的防治活性。化合物（I）或其盐可用于杀虫组合物的活性成分。

9. 发明授权

US08436049B2 Uses of pentamidine and related compounds 失效
标题翻译：戊脒和相关化合物的用途
公开(公告)号：US08436049B2
公开(公告)日：2013-05-07
申请号：US12918696
申请日：2009-02-20
申请人： John Andrew Berglund , M. Bryan Warf , Catherine Matthys , Michael M. Haley , Cameron L. Hilton
发明人： John Andrew Berglund , M. Bryan Warf , Catherine Matthys , Michael M. Haley , Cameron L. Hilton
IPC分类号： A01N37/52 , A61K31/155
CPC分类号： A61K31/155
摘要： Methods are provided herein for treatment of myotonic dystrophy and other toxic RNA diseases in a subject. In some examples, the method comprises administration of a compound that binds a nucleotide repeat expansion in a ribonucleic acid molecule, thereby treating the disease. In additional examples, the method comprises administration of a compound that disrupts binding of muscleblind-like proteins to an RNA nucleotide repeat expansion. Compounds for use in the disclosed method include pentamidine or heptamidine or derivatives thereof. Representative compounds are described herein.
摘要翻译：本文提供了用于治疗受试者中的强直性营养不良症和其它毒性RNA疾病的方法。在一些实例中，该方法包括施用结合核糖核酸分子中核苷酸重复扩增的化合物，从而治疗疾病。在另外的实施例中，该方法包括施用破坏肌肉类似蛋白质与RNA核苷酸重复扩增结合的化合物。用于所公开方法的化合物包括戊脒或七脒或其衍生物。代表性的化合物在本文中描述。

10. 发明申请

US20120328682A1 PARTICLES INCORPORATING ANTIMICROBIAL AGENTS 审中-公开
标题翻译：包含抗菌剂的颗粒
公开(公告)号：US20120328682A1
公开(公告)日：2012-12-27
申请号：US13384483
申请日：2010-07-16
申请人： James Bardwell , Scott A. Tufts, JR. , Aurelia E. Rascon , Tenoch Benitez
发明人： James Bardwell , Scott A. Tufts, JR. , Aurelia E. Rascon , Tenoch Benitez
IPC分类号： A01N37/52 , A01P1/00 , A01N25/34
CPC分类号： A01N25/08 , A01N25/34 , A01N43/40 , A01N47/44
摘要： The present invention relates generally to particles that include one or more antimicrobial agents therein and/or thereon. The particles may be provided with one or more coatings that contain one or more antimicrobial agents, or the one or more antimicrobial agents may be embedded in the particles. The present invention also relates to goods such as medical devices, personal care products, and household devices that incorporate one or more antimicrobial particles. The goods may be provided with one or more coatings that contain the antimicrobial particles, or the antimicrobial particles may be physically embedded in the medical devices. The present invention is further directed towards methods of making such medical devices. The goods incorporating the antimicrobial particles may be used in accordance with methods of killing microorganisms and preventing infections.
摘要翻译：本发明一般涉及其中和/或其上包含一种或多种抗微生物剂的颗粒。颗粒可以设置有一个或多个包含一种或多种抗微生物剂的涂层，或者一种或多种抗微生物剂可以嵌入颗粒中。本发明还涉及包含一种或多种抗微生物颗粒的诸如医疗装置，个人护理产品和家用装置的商品。所述货物可以设置有一个或多个包含所述抗微生物颗粒的涂层，或者所述抗微生物颗粒可以物理地嵌入在所述医疗装置中。本发明还涉及制造这种医疗装置的方法。可以根据杀死微生物和预防感染的方法使用结合抗微生物颗粒的物品。

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