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51. 发明授权

US3759921A Method of suppressing immuneresponse with 1 substituted-3-(2 pyrimidyl)ureas 失效
标题翻译：用1个取代的3-（2个吡啶基）磺酸酯抑制免疫球蛋白的方法
公开(公告)号：US3759921A
公开(公告)日：1973-09-18
申请号：US3759921D
申请日：1971-06-09
申请人： LILLY CO ELI
发明人： PAGET C
IPC分类号： C07D239/42 , A61K27/00
CPC分类号： C07D239/42
摘要： 1-Substituted-3-(2-pyrimidyl)ureas as immunosuppressants and as antiviral agents.
摘要翻译： 1-取代的3-（2-嘧啶基）脲作为免疫抑制剂和抗病毒剂。

52. 发明授权

US3749784A Psoriasis treatment 失效
标题翻译： PSORIASIS治疗
公开(公告)号：US3749784A
公开(公告)日：1973-07-31
申请号：US3749784D
申请日：1972-05-03
申请人： LILLY CO ELI
发明人： JOHNSON I
IPC分类号： A61K31/475 , A61K27/00
CPC分类号： A61K31/475 , Y10S514/863
摘要： PSORIASIS IS TREATED TOPICALLY, PARENTERALLY OF ORALLY WITH VINCALEUCOBLASTINE (VINBLASTINE, VLB) OR LEUROCRISTINE (VINCRISTINE).

53. 发明授权

US3747397A Test apparatus for film-forming materials 失效
标题翻译：用于成膜材料的试验装置
公开(公告)号：US3747397A
公开(公告)日：1973-07-24
申请号：US3747397D
申请日：1971-10-26
申请人： LILLY CO ELI
发明人： SHARABASH M
IPC分类号： G01N11/00 , G01N19/04
CPC分类号： G01N11/00
摘要： A gelatin film is spread on a flat steel plate from a spreader bucket and blade moved over the plate at uniform speed. To provide controlled gelling conditions, the plate temperature is held constant by water flow across its bottom and conditioned air is circulated through a housing over the plate. A plurality of test probes mounted above the plate are depressed into contact with and withdrawn from the gelatin film, in timed sequence. The probes are wetted by un-gelled film and draw strands therefrom which remain connected to the probes, whereas the probes do not draw strands from gelled film but form dimples therein. The strands and dimples may be retained as a record, and gelation time is accurately determined by observing either or both of when the successively-depressed probes cease to draw strands or start to form dimples. Strand thickness and dimple size varies at different stages to reveal gelation characteristics.
摘要翻译：将明胶膜从撒布机铲斗上分散在平板钢板上，并以均匀的速度在板上移动。为了提供可控制的胶凝条件，板材温度通过其底部的水流保持恒定，调节后的空气通过板上的壳体循环。安装在板上方的多个测试探针按照时序顺序被压下与明胶膜接触并从明胶膜中取出。探针被未凝胶膜润湿，并从其上拉出保持连接到探针的线，而探针不会从凝胶膜中拉出线，而在其中形成凹坑。股线和凹坑可以作为记录保留，并且通过观察当连续下降的探针停止汲取股线或开始形成凹坑时的任何一个或两者，可准确地确定凝胶化时间。链条厚度和凹坑尺寸在不同阶段变化以显示凝胶化特征。

54. 发明授权

US3746531A N-(2,2-difluoroalkanoyl)-2,3-pyridinediamine compounds 失效
标题翻译： N-（2,2-二氟烷基）-2,3-吡啶二胺化合物
公开(公告)号：US3746531A
公开(公告)日：1973-07-17
申请号：US3746531D
申请日：1970-03-20
申请人： LILLY CO ELI
发明人： DOHERTY G
IPC分类号： C07D213/75 , C07D213/85 , A01N9/22
CPC分类号： C07D213/75 , C07D213/85
摘要： N-(2,2 - DIFLUOROALKANOYL) - 2,3 - PYRIDINEDIAMINE COMPOUNDS USEFUL AS HERBICIDES.

55. 发明授权

US3744988A Tobacco sucker control 失效
标题翻译：烟草酱罐控制
公开(公告)号：US3744988A
公开(公告)日：1973-07-10
申请号：US3744988D
申请日：1971-12-23
申请人： LILLY CO ELI
发明人： KRUMKALNS E , MELTON H
IPC分类号： A01N43/40 , A01N5/00
CPC分类号： A01N43/40
摘要： SUBSTITUTED 3-PYRIDYLMETHANES HAVING THE FORMULA

3-(R-C(-R'')(-X)-)PYRIDINE

ARE APPLIED TO GROWING TOBACCO PLANTS TO INHIBIT THE GROWTH OF LATERALS, OR SUCKERS, ON SUCH PLANTS.

56. 发明授权

US3732204A Synthesis of acronycine and related compounds 失效
标题翻译：阿魏酰胺及其相关化合物的合成
公开(公告)号：US3732204A
公开(公告)日：1973-05-08
申请号：US3732204D
申请日：1971-07-06
申请人： LILLY CO ELI
发明人： BECK J
IPC分类号： C07D215/22 , C07D215/227 , C07D219/06 , C07D455/03 , C07D491/052 , C07D37/12
CPC分类号： C07D215/227 , C07D219/06 , C07D455/00
摘要： THE TOTAL SYNTHESIS OF ACRONYCINIC AND RELATED COMPOUNDS FROM READILY AVAILABLE STARTING MATERIALS IS DESCRIBED, AS ARE VARIOUS CLASSES OF INTRMEDIATES USEFUL IN THE SYNTHESIS.

57. 发明授权

US3728342A 3-acyloxymethyl cephalosporins and method of preparation 失效
标题翻译： 3-乙酰甲基胆碱酯及其制备方法
公开(公告)号：US3728342A
公开(公告)日：1973-04-17
申请号：US3728342D
申请日：1970-12-03
申请人： LILLY CO ELI
发明人： KUKOLJA S
IPC分类号： C07D501/26 , C07D99/24
CPC分类号： C07D501/26
摘要： 3-CYCLOALKYLCARBONYLOXYMETHYL AND 3-CYCLOALYLALKANOYLOXYMETHYL $3-CEPHALOSPORINS (E.G., 7-(2''-THIENYLACETAMIDO)-3-CYCLOBUTYLCARBONYLOXYMETHYL-$3-CEPHEM4-CARBOXYLIC ACID), ARE PREPARED BY REACTION OFA 7-ACYLAMIDO-$2-DESACETYLCEPHALOSPORIN WITH THE ANHYDRIDE OF AN ALIPHATIC CARBOXYLIC ACID TO FORM THE CORRESPONDING $2-ACYLOXYMETHYL CEPHALOSPORIN WHICH CAN BE OXIDIZED AND REDUCED TO FORM THE CORRESPONDING $3-COMPOUND.

58. 发明授权

US3712144A Automated system for performing sample measurement, dilutions and photometric measurements 失效
标题翻译：自动化系统，用于执行样品测量，稀释和光学测量
公开(公告)号：US3712144A
公开(公告)日：1973-01-23
申请号：US3712144D
申请日：1971-03-10
申请人： LILLY CO ELI
发明人： KUZEL N , KAVANAGH F
IPC分类号： B01L3/02 , G01N35/02 , G01N1/10
CPC分类号： B01L3/0203 , G01N35/026
摘要： An automatic diluter and photometric reader adapted for use in the turbidimetric microbiological assays of antibiotics, vitamins, and the like, as well as in various other analytical assays.
摘要翻译：适用于抗生素，维生素等的比浊微生物测定以及各种其他分析测定中的自动稀释和光度读数器。

59. 发明授权

US3708480A 3-cyanomethyl-delta-3-cephalosporin antibiotics and intermediates 失效
标题翻译： 3-氰基 - 三 - 三苯丙氨酸抗生素和中间体
公开(公告)号：US3708480A
公开(公告)日：1973-01-02
申请号：US3708480D
申请日：1970-11-16
申请人： LILLY CO ELI
发明人： WEBBER J , VAN HEYNINGEN E
IPC分类号： C07D501/24 , C07D99/24
CPC分类号： C07D501/24
摘要： CERTAIN 3-CYANOMETHYL, 3-OXYMETHYL, AND 3-THIOMETHYL ETHER $3-CEPHEM-4-CARBOXYLIC ACIDS, ZWITTERIONS, SALT, AND ESTERS, E.G., P-METHOXYBENZYL 7-AMINO-3-CYANOMETHYL-$3CEPHEM-4-CARBOXYLATE, A NUCELUS ESTER, AND 7-(D-A-AMINOA-PHENYLACETAMIDO)-3 - METHOXYMETHYL-$3-CEPHEM-4-CARBOXYLIC ACID, AND 7 - (D-A-AMINO-A-PHENYLACETAMIDO)-3METHYLTHIOMETHYL-$3-CEPHEM-4-CARBOXYLIC ACID, NEW CEPHALOSPORIN ANTIOBITICS.

60. 发明授权

US3702328A Process for preparing thiazole derivatives 失效
标题翻译：制备噻唑衍生物的方法
公开(公告)号：US3702328A
公开(公告)日：1972-11-07
申请号：US3702328D
申请日：1969-05-16
申请人： LILLY CO ELI
发明人： KUKOLJA STEPHAN P , MORIN ROBERT B
IPC分类号： C07D263/42 , C07D277/56
CPC分类号： C07D263/42
摘要： PROCESS FOR PREPARING THIAZOLECARBONYLAMINO-SUBSTITUTED BUTENOIC ACIDS AND NEW THIAZOLECARBONYLAMINOSUBSTITUTED OXAZOLONE COMPOUNDS, E.G., 2-(N-(2''-PHENOXYMETHYL-4-THIAZOLYL)CARBONYL)AMINO-3- METHYLBUTENOIC ACID, AND 2-(2''-PENOXYMETHYL-4''-THIAZOLYL)-4ISOPROPYLIDENE-5- OXAZOLONE BY TREATING A 2-(2-SUBSTITUTEDAMIDO-1-THIOACETYL-2-ETHENYL)-4-ISOPROPYLIDENE-5-OXAZOLONE WITH ACID OR BASE, IN AN INERT ORGANIC SOLVENT, OR IN ADMIXTURE WITH THE ALCOHOL OF THE DESIRED ESTER, WHICH PRODUCTS OF THE PROCESS CAN BE USED AS ANTIBIOTICS AND ANTIFUNGAL AGENTS, AS INTERMEDIATES IN THE SYNTHESIS OF PENICILLIN AND CEPHALOSPORIN COMPOUNDS AND AS ANTI-RADIATION CHEMICALS.

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