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51. 发明授权

US08764786B2 Balloon catheters and methods for treating paranasal sinuses 有权
标题翻译：气球导管和治疗鼻旁窦的方法
公开(公告)号：US08764786B2
公开(公告)日：2014-07-01
申请号：US13648111
申请日：2012-10-09
申请人： Acclarent, Inc.
发明人： Bruce B. Becker
IPC分类号： A61M29/00
CPC分类号： A61M29/02 , A61B17/32 , A61M25/10 , A61M25/1002 , A61M25/10181 , A61M2210/0618 , A61M2210/0681
摘要： A set of sinus balloon catheters are provided for treating a patient's paranasal sinus system, including dilating prepared openings, and natural ostia and ducts and excising sinus cavities. These include a balloon catheter with a bend placing a distal segment at 90° to a proximal segment and a balloon catheter which is substantially straight. The catheters have sufficient stiffness and column strength that the balloon carrying distal segment of the catheter can be pushed into the prepared opening, natural ostium or duct, or sinus to be excised. The catheters have appropriate inflated working diameters and appropriate outer diameters with the balloon deflated that will enable the catheter to be pushed into the respective prepared opening, natural ostium or duct, or sinus cavity to be excised. The methods use the balloon catheters to dilate prepared openings to selected parts of the sinus system, to dilate natural ostia and ducts of the sinus system, and/or to dilate sinus cavities to remove them.
摘要翻译：提供了一套用于治疗患者的鼻旁窦系统的鼻窦气囊导管，包括扩张的准备的开口，以及天然的口腔和导管以及切除的窦腔。这些包括具有弯曲部的气囊导管，其将远侧部分放置在近端部分90°处，并且气球导管基本上是直的。导管具有足够的刚度和柱强度，使得携带导管的远端部分的气囊可以被推入准备的开口，天然口或管道或窦中以被切除。导管具有适当的充气工作直径和适当的外径，气囊放气，使得导管能够被推入相应制备的开口，天然口或导管或窦腔中以被切除。该方法使用气囊导管将制备的开口扩张到窦系统的选定部分，以扩张窦系统的天然口和管道，和/或扩张窦腔以除去它们。

52. 发明授权

US08764709B2 Devices, systems and methods for treating disorders of the ear, nose and throat 有权
公开(公告)号：US08764709B2
公开(公告)日：2014-07-01
申请号：US12828170
申请日：2010-06-30
申请人： John Y. Chang , Joshua Makower , Julia D. Vrany , Theodore C. Lamson , Amrish Jayprakash Walke
发明人： John Y. Chang , Joshua Makower , Julia D. Vrany , Theodore C. Lamson , Amrish Jayprakash Walke
IPC分类号： A61M5/178
CPC分类号： A61F11/002 , A61B5/065 , A61B10/06 , A61B17/1204 , A61B17/12045 , A61B17/12104 , A61B17/12136 , A61B17/1604 , A61B17/1608 , A61B17/1679 , A61B17/1688 , A61B17/24 , A61B17/32002 , A61B17/32075 , A61B17/3478 , A61B34/20 , A61B50/13 , A61B50/15 , A61B50/20 , A61B90/16 , A61B90/361 , A61B2017/00247 , A61B2017/003 , A61B2017/320004 , A61B2017/3486 , A61B2017/3488 , A61B2018/00392 , A61B2034/2051 , A61F2/958 , A61F2250/0067 , A61M25/007 , A61M25/10 , A61M2025/105 , A61M2025/1052
摘要： Sinusitis, mucocysts, tumors, infections, hearing disorders, choanal atresia, fractures and other disorders of the paranasal sinuses, Eustachian tubes, Lachrymal ducts and other ear, nose, throat and mouth structures are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies and endoscopic studies. Access and occluding devices may be used to facilitate insertion of working devices such asendoscopes, wires, probes, needles, catheters, balloon catheters, dilation catheters, dilators, balloons, tissue cutting or remodeling devices, suction or irrigation devices, imaging devices, sizing devices, biopsy devices, image-guided devices containing sensors or transmitters, electrosurgical devices, energy emitting devices, devices for injecting diagnostic or therapeutic agents, devices for implanting devices such as stents, substance eluting or delivering devices and implants, etc.

53. 发明授权

US08740929B2 Spacing device for releasing active substances in the paranasal sinus 有权
标题翻译：用于释放鼻窦中活性物质的间隔装置
公开(公告)号：US08740929B2
公开(公告)日：2014-06-03
申请号：US10470881
申请日：2002-02-06
申请人： Achim Gopferich , Werner Hosemann
发明人： Achim Gopferich , Werner Hosemann
IPC分类号： A61L31/16 , A61L31/10
CPC分类号： A61L31/10 , A61F2/186 , A61K9/0043 , A61K9/0092 , A61L31/16 , A61L2300/222 , A61L2300/258 , A61L2300/414 , A61L2300/43 , A61L2300/432 , A61L2300/434 , A61L2300/602
摘要： A spacing device for use in fenestrations of the paranasal sinus, the device including a sheath which forms a hollow body defining at least two apertures. The sheath includes at least one layer loaded with an active substance. The ratio q of the external diameter ra of the hollow body to the internal diameter ri of the hollow body is about 1.2 to 3.0.
摘要翻译：用于鼻旁窦开窗的间隔装置，该装置包括形成限定至少两个孔的中空体的护套。护套包括装载有活性物质的至少一层。中空体的外径ra与中空体的内径ri的比q为约1.2〜3.0。

54. 发明授权

US08715169B2 Devices, systems and methods useable for treating sinusitis 有权
公开(公告)号：US08715169B2
公开(公告)日：2014-05-06
申请号：US11928097
申请日：2007-10-30
申请人： John Y. Chang , Joshua Makower , Julia D. Vrany , John H. Morriss , Ketan P. Muni , Isaac J. Kim , Hung Ha , William M. Facteau , Amrish Jayprakash Walke
发明人： John Y. Chang , Joshua Makower , Julia D. Vrany , John H. Morriss , Ketan P. Muni , Isaac J. Kim , Hung Ha , William M. Facteau , Amrish Jayprakash Walke
IPC分类号： A61B1/04 , A61B1/00
CPC分类号： A61M29/00 , A61B1/233 , A61B17/12104 , A61B17/12136 , A61B17/1657 , A61B17/1688 , A61B17/24 , A61B17/320016 , A61B17/320725 , A61B34/20 , A61B2017/00292 , A61B2017/246 , A61B2034/2051 , A61B2090/3764 , A61B2503/40 , A61M25/0041 , A61M25/0054 , A61M25/0662 , A61M25/09 , A61M25/1002 , A61M29/02 , A61M2025/0008 , A61M2025/1079 , A61M2029/025 , A61M2210/0618 , A61M2210/1028
摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

55. 发明授权

US08702722B2 System and method for the simultaneous automated bilateral delivery of pressure equalization tubes 有权
标题翻译：用于同时自动双向输送压力平衡管的系统和方法
公开(公告)号：US08702722B2
公开(公告)日：2014-04-22
申请号：US13164993
申请日：2011-06-21
申请人： Erik James Shahoian
发明人： Erik James Shahoian
IPC分类号： A61F11/00
CPC分类号： A61M31/00 , A61B5/0077 , A61B2017/00787 , A61F11/002 , A61F2230/0039 , A61F2230/0052 , A61F2250/0039 , A61M2210/0662 , A61N1/30 , A61N1/306
摘要： Systems and methods for treating a patient having a head with a first ear and a second ear, function by aligning a first device with a tympanic membrane of the first ear; inputting a command to an input device operatively coupled to the first device to generate a signal; and actuating the first device in response to the signal so as to drive a penetrator of the device through the tympanic membrane.
摘要翻译：用于治疗具有第一耳朵和第二耳朵的头部的患者的系统和方法通过使第一装置与第一耳朵的鼓膜对准而起作用; 向可操作地耦合到所述第一设备的输入设备输入命令以产生信号; 以及响应于所述信号致动所述第一装置，以便通过所述鼓膜驱动所述装置的穿透器。

56. 发明授权

US08702626B1 Guidewires for performing image guided procedures 有权
标题翻译：导线执行图像引导程序
公开(公告)号：US08702626B1
公开(公告)日：2014-04-22
申请号：US11648158
申请日：2006-12-29
申请人： Isaac J. Kim , Eric Goldfarb , Tom T. Vo , Robert K. Deckman
发明人： Isaac J. Kim , Eric Goldfarb , Tom T. Vo , Robert K. Deckman
IPC分类号： A61B5/05 , A61B5/00 , A61M25/00
CPC分类号： A61B5/062 , A61B5/055 , A61B5/06 , A61B5/6851 , A61B6/032 , A61B17/24 , A61B17/320725 , A61B17/320758 , A61B17/320783 , A61B17/3478 , A61B34/20 , A61B90/16 , A61B90/361 , A61B90/39 , A61B2017/22042 , A61B2017/22061 , A61B2034/2048 , A61B2034/2051 , A61B2090/363 , A61B2090/365 , A61B2090/3958 , A61B2090/3983 , A61M25/09 , A61M25/09041 , A61M29/02 , A61M2025/0166 , A61M2025/09083 , A61M2025/09175 , A61M2029/025
摘要： Guidewires and methods useable in conjunction with image guidance systems to facilitate performance of diagnostic or therapeutic tasks at locations within the bodies of human or animal subjects.
摘要翻译：导线和方法可与图像引导系统结合使用，以促进在人或动物主体的身体内的位置执行诊断或治疗任务。

57. 发明申请

US20130231529A1 DEVICES, SYSTEMS AND METHODS FOR DIAGNOSING AND TREATING SINUSITIS ANDOTHER DISORDERS OF THE EARS, NOSE AND/OR THROAT 审中-公开
标题翻译：用于诊断和治疗神经病，鼻咽癌和/或肝脏的神经病变的装置，系统和方法
公开(公告)号：US20130231529A1
公开(公告)日：2013-09-05
申请号：US13867972
申请日：2013-04-22
申请人： ACCLARENT, INC.
发明人： Chang Y. John , Makower Joshua
IPC分类号： A61B17/24
CPC分类号： A61B17/24 , A61B1/233 , A61B1/313 , A61B10/0233 , A61B10/06 , A61B17/0218 , A61B17/1688 , A61B17/29 , A61B17/3201 , A61B17/32053 , A61B17/32056 , A61B17/320725 , A61B17/320758 , A61B17/320783 , A61B17/3478 , A61B18/02 , A61B18/042 , A61B18/12 , A61B18/18 , A61B2017/00477 , A61B2017/22061 , A61B2017/320052 , A61B2017/320064 , A61B2018/00327 , A61B2018/00595 , A61B2018/0212 , A61B2018/1405 , A61B2217/005 , A61B2217/007 , A61F2/18 , A61F2/186 , A61F2/82 , A61F11/004 , A61F13/2005 , A61F2250/0039 , A61M16/0434 , A61M25/10 , A61M29/02 , A61M31/00 , A61M31/005 , A61N1/0541
摘要： Sinusitis, enlarged nasal turbinates, tumors, infections, hearing disorders, allergic conditions, facial fractures and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies, endoscopic studies and transillumination studies. Access and occluder devices may be used to establish fluid tight seals in the anterior or posterior nasal cavities/nasopharynx and to facilitate insertion of working devices (e.g., scopes, guidewires, catheters, tissue cutting or remodeling devices, electrosurgical devices, energy emitting devices, devices for injecting diagnostic or therapeutic agents, devices for implanting devices such as stents, substance eluting devices, substance delivery implants, etc.
摘要翻译：使用微创方法诊断和/或治疗鼻窦炎，扩大的鼻甲，肿瘤，感染，听力障碍，过敏症状，面部骨折和其他疾病，并且在许多情况下，柔性导管与仪器相反具有刚性轴。使用各种诊断程序和装置进行成像研究，粘液流研究，空气/气体流动研究，解剖维度研究，内镜研究和透照研究。可以使用进入和闭塞器装置在前鼻/鼻后鼻/鼻咽中建立流体密封，并且便于插入工作装置（例如，示波器，导丝，导管，组织切割或重塑装置，电外科装置，能量发射装置，用于注射诊断或治疗剂的装置，用于植入装置如支架，物质洗脱装置，物质输送植入物等的装置

58. 发明授权

US08439687B1 Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices 有权
标题翻译：用于模拟插入和定位导向装置和其他介入装置的装置和方法
公开(公告)号：US08439687B1
公开(公告)日：2013-05-14
申请号：US11648159
申请日：2006-12-29
申请人： John H. Morriss , John Y. Chang
发明人： John H. Morriss , John Y. Chang
IPC分类号： G09B23/28
CPC分类号： G09B23/285
摘要： Apparatus and methods useable for simulated insertion and positioning of medical or surgical devices. The apparatus generally comprises a substantially flat structure having simulated body openings, anatomical passageways, anatomical structures and anatomical cavities formed therein. One or more windows (e.g., a transparent top panel or cover) allows the operator to observe the movement or positioning of the medical or surgical device.
摘要翻译：用于医疗或外科手术装置的模拟插入和定位的装置和方法。该装置通常包括具有模拟体开口，解剖通道，解剖结构和形成在其中的解剖腔的基本平坦的结构。一个或多个窗口（例如，透明顶板或盖）允许操作者观察医疗或手术装置的移动或定位。

59. 发明授权

US08425488B2 System and method for the simultaneous bilateral treatment of target tissues within the ears using a guide block structure 有权
标题翻译：使用引导块结构同时双边处理耳内靶组织的系统和方法
公开(公告)号：US08425488B2
公开(公告)日：2013-04-23
申请号：US11749733
申请日：2007-05-16
申请人： Anton Clifford , Greg Liu , John Morriss , Joshua Makower , William Facteau , Eric Goldfarb , John Y. Chang
发明人： Anton Clifford , Greg Liu , John Morriss , Joshua Makower , William Facteau , Eric Goldfarb , John Y. Chang
IPC分类号： A61M31/00 , A61M1/00 , A61M3/02 , A61M3/00 , A61N1/30
CPC分类号： A61M31/00 , A61B5/0077 , A61B2017/00787 , A61F11/002 , A61F2230/0039 , A61F2230/0052 , A61F2250/0039 , A61M2210/0662 , A61N1/30 , A61N1/306
摘要： Systems and methods for treating a patient having a head with a first ear and a second ear, function by mounting a support structure to the head of the patient; aligning the support structure with a target tissue in an ear canal of the first ear; stabilizing the support structure relative to the target tissue by injecting a material into the canal and hardening the material; and actuating a device while the device is supported by the support system so that the device therapeutically remodels the target tissue of the first ear.
摘要翻译：用于治疗患有具有第一耳朵和第二耳朵的头部的患者的系统和方法通过将支撑结构安装到患者的头部而起作用; 将支撑结构与第一耳的耳道中的目标组织对准; 通过将材料注入到管道中并使材料硬化来相对于目标组织稳定支撑结构; 以及当所述装置由所述支撑系统支撑时启动装置，使得所述装置治疗性地改造所述第一耳朵的目标组织。

60. 发明申请

US20130096605A1 BALLOON CATHETERS AND METHODS FOR TREATING PARANASAL SINUSES 有权
标题翻译：气球导管及其处理方法
公开(公告)号：US20130096605A1
公开(公告)日：2013-04-18
申请号：US13648111
申请日：2012-10-09
申请人： Bruce B. Becker
发明人： Bruce B. Becker
IPC分类号： A61M29/02
CPC分类号： A61M29/02 , A61B17/32 , A61M25/10 , A61M25/1002 , A61M25/10181 , A61M2210/0618 , A61M2210/0681
摘要： A set of sinus balloon catheters are provided for treating a patient's paranasal sinus system, including dilating prepared openings, and natural ostia and ducts and excising sinus cavities. These include a balloon catheter with a bend placing a distal segment at 90° to a proximal segment and a balloon catheter which is substantially straight. The catheters have sufficient stiffness and column strength that the balloon carrying distal segment of the catheter can be pushed into the prepared opening, natural ostium or duct, or sinus to be excised. The catheters have appropriate inflated working diameters and appropriate outer diameters with the balloon deflated that will enable the catheter to be pushed into the respective prepared opening, natural ostium or duct, or sinus cavity to be excised. The methods use the balloon catheters to dilate prepared openings to selected parts of the sinus system, to dilate natural ostia and ducts of the sinus system, and/or to dilate sinus cavities to remove them.
摘要翻译：提供了一套用于治疗患者的鼻旁窦系统的鼻窦气囊导管，包括扩张的准备的开口，以及天然的口腔和导管以及切除的窦腔。这些包括具有弯曲部的气囊导管，其将远侧部分放置在近端部分90°处，并且气球导管基本上是直的。导管具有足够的刚度和柱强度，使得携带导管的远端部分的气囊可以被推入准备的开口，天然口或管道或窦中以被切除。导管具有适当的充气工作直径和适当的外径，气囊放气，使得导管能够被推入相应制备的开口，天然口或导管或窦腔中以被切除。该方法使用气囊导管将制备的开口扩张到窦系统的选定部分，以扩张窦系统的天然口腔和管道，和/或扩张窦腔以除去它们。

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