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61. 发明授权

US07811598B2 AXMI-028 and AXMI-029, a family of novel delta-endotoxin genes and methods for their use 有权
公开(公告)号：US07811598B2
公开(公告)日：2010-10-12
申请号：US12166253
申请日：2008-07-01
申请人： Nadine Carozzi , Michael G. Koziel , Tracy Hargiss , Nicholas B. Duck
发明人： Nadine Carozzi , Michael G. Koziel , Tracy Hargiss , Nicholas B. Duck
IPC分类号： A01N25/00 , A61K38/16 , C12P21/02
CPC分类号： C07K14/325 , C12N15/8286 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 4, 15, 17, or 19, or the nucleotide sequence set forth in SEQ ID NO:1, 3, 14, 16, or 18, as well as variants and fragments thereof.

62. 发明授权

US07807881B2 Methods to confer herbicide resistance 失效
标题翻译：赋予除草剂抗性的方法
公开(公告)号：US07807881B2
公开(公告)日：2010-10-05
申请号：US11588811
申请日：2006-10-27
申请人： Philip E. Hammer , Todd K. Hinson , Nicholas B. Duck , Michael G. Koziel
发明人： Philip E. Hammer , Todd K. Hinson , Nicholas B. Duck , Michael G. Koziel
IPC分类号： C12N15/82 , A01H5/00 , A01H5/10
CPC分类号： C12N15/8274 , C12N9/88 , C12N15/8275
摘要： Compositions and methods for conferring herbicide resistance to plant cells and bacterial cells are provided. The methods comprise transforming the cells with nucleotide sequences encoding herbicide resistance genes. In particular, herbicide resistance is conferred by expression of proteins with homology to decarboxylase enzymes. Compositions comprise transformed plants, plant tissues, and seeds, as well as transformed bacterial cells.
摘要翻译：提供了赋予对植物细胞和细菌细胞的除草剂抗性的组合物和方法。所述方法包括用编码除草剂抗性基因的核苷酸序列转化细胞。特别地，通过与脱羧酶具有同源性的蛋白质的表达赋予除草剂抗性。组合物包括转化的植物，植物组织和种子，以及转化的细菌细胞。

63. 发明授权

US09862965B2 AXMI205 variant proteins and methods of use 有权
公开(公告)号：US09862965B2
公开(公告)日：2018-01-09
申请号：US14233426
申请日：2012-07-27
申请人： Volker Heinrichs , Jayme Williams
发明人： Volker Heinrichs , Jayme Williams
IPC分类号： C12N15/82 , C07K14/325 , A01N37/46 , A01N65/00 , A01N63/02
CPC分类号： C12N15/8279 , A01N37/46 , A01N63/02 , A01N65/00 , C07K14/325 , C12N15/8286 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:7, 8, 9, 10, 11, or 12, the nucleotide sequence set forth in SEQ ID NO:4, 5, or 6, as well as variants and fragments thereof.

64. 发明申请

US20160185830A1 AXMI440 TOXIN GENE AND METHODS FOR ITS USE 审中-公开
标题翻译： AXMI440毒素基因及其使用方法
公开(公告)号：US20160185830A1
公开(公告)日：2016-06-30
申请号：US14910474
申请日：2014-08-08
申请人： ATHENIX CORP
发明人： Rebecca Thayer , Kimberly S. Sampson , Duane Lehtinen , Leonardo Magalhaes
IPC分类号： C07K14/325 , C12N15/82 , A01N63/02
CPC分类号： C12N15/8286 , C07K14/325
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:3-6, or the nucleotide sequence set forth in SEQ ID NO: 1 or 2, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：3-6所示的氨基酸序列的核苷酸序列或SEQ ID NO：1或2所示的核苷酸序列，以及变体和片段。

65. 发明授权

US09243259B2 Genes encoding nematode toxins 有权
公开(公告)号：US09243259B2
公开(公告)日：2016-01-26
申请号：US13747740
申请日：2013-01-23
申请人： ATHENIX CORPORATION
发明人： Cheryl L. Peters , Brian Vande Berg , Brian Carr , Julia T. Daum , Vadim Beilinson , Sandra Volrath , Candace Poutre , Kimberly Sampson
IPC分类号： C12N15/82 , C12N9/02
CPC分类号： C12N15/8241 , C12N9/0059 , C12N9/0071 , C12N15/8285 , C12Y110/03001 , C12Y114/18001 , Y02A40/164
摘要： Compositions and methods for conferring nematicidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions including a coding sequence for nematicidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated nematicidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules including nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:4, 5, 8, 9, 13, 14, 47, 48, or 49, the nucleotide sequence set forth in SEQ ID NO:1, 2, 3, 6, 7, 10, 11, 12, 15, 45, or 46, as well as variants and fragments thereof.

66. 发明申请

US20140373195A1 AXMI345 DELTA-ENDOTOXIN GENE AND METHODS FOR ITS USE 有权
标题翻译： AXMI345 DELTA-ENDOTOXIN基因及其使用方法
公开(公告)号：US20140373195A1
公开(公告)日：2014-12-18
申请号：US14376944
申请日：2013-03-07
申请人： Athenix Corp.
发明人： Kimberly Sampson , Rebecca Thayer , Duane Lehtinen
IPC分类号： C12N15/82 , C07K14/325
CPC分类号： C12N15/8286 , C07K14/325
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, or the nucleotide sequence set forth in SEQ ID NO: 1 or 3, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：2所示的氨基酸序列的核苷酸序列或SEQ ID NO：1或3所示的核苷酸序列，以及其变体和片段。

67. 发明授权

US08791326B2 AXMI-150 delta-endotoxin gene and methods for its use 有权
标题翻译： AXMI-150δ-内毒素基因及其使用方法
公开(公告)号：US08791326B2
公开(公告)日：2014-07-29
申请号：US13302428
申请日：2011-11-22
申请人： Kimberly S. Sampson , Daniel J. Tomso , Volker Heinrichs
发明人： Kimberly S. Sampson , Daniel J. Tomso , Volker Heinrichs
IPC分类号： C12N15/63 , C12N15/82 , C12N1/21 , C12N5/10 , A01H5/00
CPC分类号： C12N15/8286 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions including a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules having nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, the nucleotide sequence set forth in SEQ ID NO:1, 3, 4, 5, 6, 7, 8, 9, 10, 11, or 12, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包括杀虫多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的杀虫核酸分子。另外，包括对应于多核苷酸的氨基酸序列。具体而言，本发明提供了具有编码SEQ ID NO：2所示氨基酸序列的核苷酸序列的分离的核酸分子，即SEQ ID NO：1,3,4,5,6,7， 8，9，10，11或12，以及其变体和片段。

68. 发明申请

US20140051829A1 AXMI-205 PESTICIDAL GENE AND METHOD FOR ITS USE 审中-公开
标题翻译： AXMI-205农药基因及其使用方法
公开(公告)号：US20140051829A1
公开(公告)日：2014-02-20
申请号：US14057300
申请日：2013-10-18
申请人： Athenix Corp.
发明人： Nalini Manoj Desai , Jill Hinson , Deepa Balasubramanian , Kimberly S. Sampson , Daniel J. Tomso , Duane Alan Lehtinen , Nicholas B. Duck , Rong Guo , Volker Heinrichs
IPC分类号： C07K14/195
CPC分类号： C07K14/195 , C07K14/22 , C07K16/1203 , C12N15/8285 , C12N15/8286 , C12Q1/6876 , Y02A40/162 , Y02A40/164
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 3, or 4, the nucleotide sequence set forth in SEQ ID NO:1, 9, 10, or 11, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含杀虫多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的杀虫核酸分子。另外，包括对应于多核苷酸的氨基酸序列。特别地，本发明提供了包含编码SEQ ID NO：2,3或4所示氨基酸序列的核苷酸序列的核酸分子，SEQ ID NO：1,9,10或11所示的核苷酸序列，以及其变体和片段。

69. 发明申请

US20140033363A1 AXMI238 TOXIN GENE AND METHODS FOR ITS USE 有权
标题翻译： AXMI238毒素基因及其使用方法
公开(公告)号：US20140033363A1
公开(公告)日：2014-01-30
申请号：US14007685
申请日：2012-03-29
申请人： Kimberly Sampson
发明人： Kimberly Sampson
IPC分类号： C07K14/32 , C12N15/82
CPC分类号： C07K14/32 , C07K14/325 , C07K2319/24 , C12N15/8286 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2-5, or the nucleotide sequence set forth in SEQ ID NO: 1, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：2-5所示的氨基酸序列的核苷酸序列或SEQ ID NO：1所示的核苷酸序列，以及其变体和片段。

70. 发明授权

US08461421B2 Toxin genes and methods for their use 有权
标题翻译：毒素基因及其使用方法
公开(公告)号：US08461421B2
公开(公告)日：2013-06-11
申请号：US12491396
申请日：2009-06-25
申请人： Kimberly S. Sampson , Daniel John Tomso , Shruti Agarwal , Brian McNulty , Chris Campbell
发明人： Kimberly S. Sampson , Daniel John Tomso , Shruti Agarwal , Brian McNulty , Chris Campbell
IPC分类号： A01H5/00 , C12N15/31 , C12N15/82 , A01N37/18 , C07K14/325 , C12P21/02 , C12N1/21
CPC分类号： C07K14/325 , A01N37/18 , C07K16/1278 , C12N15/8286 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:61-121 and 133-141, or the nucleotide sequence set forth in SEQ ID NO:1-60, 124-132, and 142-283, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含δ-内毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的δ-内毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：61-121和133-141所示的氨基酸序列的核苷酸序列或SEQ ID NO：1-60,124所示的核苷酸序列 -132和142-283，以及其变体和片段。

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