会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 72. 发明授权
    • Bioinformatically detectable viral regulatory genes
    • 生物信息学检测的病毒调控基因
    • US07759478B1
    • 2010-07-20
    • US10604984
    • 2003-08-29
    • Itzhak Bentwich
    • Itzhak Bentwich
    • C07H21/04A61K31/70
    • C12N15/1132C07K14/005C12N15/111C12N15/1131C12N2310/14C12N2320/11C12N2330/10C12N2740/16022Y02A90/26
    • The present invention relates to a group of novel viral RNA regulatory genes, here identified as “viral genomic address messenger genes” or “VGAM genes”, and as “genomic record” or “GR” genes. VGAM genes selectively inhibit translation of known host target genes, and are believed to represent a novel pervasive viral attack mechanism. GR genes encode an operon-like cluster of VGAM genes. VGAM and viral GR genes may therefore be useful in diagnosing, preventing and treating viral disease. Several nucleic acid molecules are provided respectively encoding several VGAM genes, as are vectors and probes, both comprising the nucleic acid molecules, and methods and systems for detecting VGAM genes, and for counteracting their activity.
    • 本发明涉及一组新的病毒RNA调节基因,这些基因被鉴定为“病毒基因组地址信使基因”或“VGAM基因”,以及“基因组记录”或“GR”基因。 VGAM基因选择性地抑制已知宿主靶基因的翻译,并且被认为代表了一种新的普遍的病毒攻击机制。 GR基因编码VGAM基因的操纵子样簇。 因此,VGAM和病毒GR基因可用于诊断,预防和治疗病毒性疾病。 提供了分别编码若干VGAM基因的核酸分子,以及包含核酸分子的载体和探针以及用于检测VGAM基因的方法和系统以及抵消其活性。
    • 73. 发明授权
    • Missing store operation accelerator
    • 缺少商店操作加速器
    • US07757047B2
    • 2010-07-13
    • US11271056
    • 2005-11-12
    • Santosh G. AbrahamLawrence A. SpracklenYuan C. Chou
    • Santosh G. AbrahamLawrence A. SpracklenYuan C. Chou
    • G06F13/16
    • G06F12/0859
    • Maintaining a cache of indications of exclusively-owned coherence state for memory space units (e.g., cache line) allows reduction, if not elimination, of delay from missing store operations. In addition, the indications are maintained without corresponding data of the memory space unit, thus allowing representation of a large memory space with a relatively small missing store operation accelerator. With the missing store operation accelerator, a store operation, which misses in low-latency memory (e.g., L1 or L2 cache), proceeds as if the targeted memory space unit resides in the low-latency memory, if indicated in the missing store operation accelerator. When a store operation misses in low-latency memory and hits in the accelerator, a positive acknowledgement is transmitted to the writing processing unit allowing the store operation to proceed. An entry is allocated for the store operation, the store data is written into the allocated entry, and the target of the store operation is requested from memory. When a copy of the data at the requested memory space unit returns, the rest of the allocated entry is updated.
    • 维护用于存储器空间单元(例如,高速缓存行)的专有相干状态的指示的缓存允许减少(如果不是消除)缺失存储操作的延迟。 此外,在没有存储器空间单元的相应数据的情况下维持指示,从而允许用相对较小的缺少存储操作加速器来表示大的存储空间。 在缺少存储操作加速器的情况下,在低延迟存储器(例如L1或L2高速缓存)中丢失的存储操作如同目标存储器空间单元驻留在低延迟存储器中那样进行,如果在缺少的存储操作 加速器。 当存储操作在低延迟存储器中错过并且在加速器中点击时,肯定确认被发送到写入处理单元,从而允许存储操作继续进行。 为存储操作分配条目,将存储数据写入分配的条目,并且从存储器请求存储操作的目标。 当所请求的存储器空间单元上的数据的副本返回时,所分配的条目的其余部分被更新。
    • 77. 发明授权
    • Bioinformatically detectable group of novel viral regulatory genes and uses thereof
    • 生物信息学可检测的新型病毒调节基因及其用途
    • US07696342B1
    • 2010-04-13
    • US10604945
    • 2003-08-27
    • Itzhak Bentwich
    • Itzhak Bentwich
    • C07H21/04
    • C12N15/1131C07H21/02C12Q1/701
    • The present invention relates to a group of novel viral RNA regulatory genes, here identified as “viral genomic address messenger genes” or “VGAM genes”, and as “genomic record” or “GR” genes. VGAM genes selectively inhibit translation of known host target genes, and are believed to represent a novel pervasive viral attack mechanism. GR genes encode an operon-like cluster of VGAM genes. VGAM and viral GR genes may therefore be useful in diagnosing, preventing and treating viral disease. Several nucleic acid molecules are provided respectively encoding several VGAM genes, as are vectors and probes, both comprising the nucleic acid molecules, and methods and systems for detecting VGAM genes, and for counteracting their activity.
    • 本发明涉及一组新的病毒RNA调节基因,这些基因被鉴定为“病毒基因组地址信使基因”或“VGAM基因”,以及“基因组记录”或“GR”基因。 VGAM基因选择性地抑制已知宿主靶基因的翻译,并且被认为代表了一种新的普遍的病毒攻击机制。 GR基因编码VGAM基因的操纵子样簇。 因此,VGAM和病毒GR基因可用于诊断,预防和治疗病毒性疾病。 提供了分别编码若干VGAM基因的核酸分子,以及包含核酸分子的载体和探针以及用于检测VGAM基因的方法和系统以及抵消其活性。