专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

71. 发明授权

US3773746A 1,1'-azo bis(1h-imidazo(1,2-a)pyridinium dibromide compounds 失效
标题翻译： 1,1'-偶氮二（1H-咪唑（1,2-A）吡啶二酮化合物
公开(公告)号：US3773746A
公开(公告)日：1973-11-20
申请号：US3773746D
申请日：1971-05-13
申请人： ALLEN & HANBURYS LTD
发明人： JACK D , GLOVER E
IPC分类号： C07D213/77 , C07D233/54 , C07D235/22 , C07D471/04 , C07D519/00 , C07C115/00
CPC分类号： C07D213/77 , C07C243/00 , C07D233/54 , C07D235/22 , C07D471/04
摘要： THERE ARE PROVIDED COMPOUNDS OF THE GENERAL FORMULA

(2-R3,3-R4,4-R2,5-R1-1H-IMIDAZOL-1-YL)2-N2 (X(-))2

IN WHICH R1-R4 WHICH MAY BE THE SAME OR DIFFERENT REPRESENT LOWER ALKYL, LOWER ALKENYL, HALOGEN, ARALKYL OR ARYL IN WHICH THE ARYL GROUP MAY BE SUBSTITUTED WITH HYDROXY, LOWER ALKOXY, HALOGEN, NITRO OR TRIFLUOROMETHYL AND IN WHICH ANY TWO ADJACENT GROUPS R MAY TOGETHER WITH 2 ATOMS OF THE IMIDAZOLE RING FORM A 5, 6 OR 7 MEMBERED CARBOCYCLIC OR HETEROCYCLIC RING; AND X REPRESENTS A PHYSIOLOGICALLY ACCEPTABLE ANION. THESE COMPOUNDS HAVE A CURARE LIKE NEUROMUSCULAR BLOCKING ACTION.

72. 发明授权

US3733374A Thiophosphate acetyl hydrazines 失效
标题翻译：硫代磷酸乙酯
公开(公告)号：US3733374A
公开(公告)日：1973-05-15
申请号：US3733374D
申请日：1970-04-24
申请人： EXXON RESEARCH ENGINEERING CO
发明人： ZIELINSKI J
IPC分类号： A01N57/02 , C07D213/77 , C07F9/165 , C07F9/16 , A01N9/36
CPC分类号： C07D213/77 , A01N57/02 , C07F9/1651
摘要： ORGANOPHOSPHOROUS COMPOUNDS REPRESENTED BY THE FOLLOWING STRUCTURE:

R-P(=X)(-R1)-S-(C(-R2)(-R3))N-C(=X)-N(-R4)-N(-R5)-R6

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

-(C(-R2)(-R3))A-Z, -(C(-R2)(-R3))A-L-(C(-R2)(-R3))-H,

-Y-A

SUBSTITUTED OR UNSUBSTITUTED ARYL AND HETEROARYL, WHEREIN Z=CN, COOR2, CON(R2)2, NO2, SO2N(R2)2, COOH, TRIHALOALKYL,

O=CH-, O=C(-R2)-

WHEREIN L=O, S, SO, SO2, NH, NR2,

-CO-, -C(=S)-, -C(=N-R2)-, Y=C=O, -C(=S)-

SO, SO2, A=OR2, SR2, NHR2, N(R2)2 AND A IS AN INTEGER RANGING FROM 1 TO 6, WITH THE PROVISO THAT WHEN R5 IS THE SAME AS R2, THEN R6 CANNOT BE R2 EXCEPT WHEN R5 OR R6 IS ARYL OR HETEROARYL.

73. 发明授权

US3686244A Metal complexes of dithiobiurets 失效
标题翻译：二氢铋的金属络合物
公开(公告)号：US3686244A
公开(公告)日：1972-08-22
申请号：US3686244D
申请日：1970-04-27
申请人： EXXON RESEARCH ENGINEERING CO
发明人： MARKS ALFRED F
IPC分类号： C07C337/06 , C07D213/40 , C07D213/77 , C07D295/215 , C07D295/28 , C07D307/14 , C07D307/52 , C07F1/08 , C07F3/06 , C07F13/00 , C07F15/00 , C07F15/02 , C07F15/04 , C07F15/06
CPC分类号： C07D213/40 , C07D213/77 , C07D295/215 , C07D295/32 , C07D307/14 , C07D307/52
摘要： METAL COMPLEXES OF KITHIOIURETS HAVE BEEN FOUND TO EXHIBIT EFFECTIVE FUNGICIDAL AND GROWTH REGULATING ACTIVITY. EXEMPLARY OF SUCH COMPOUNDS ARE THOSE REPRESENTED BY THE FOLLOWING STRUCTURE:

R1-N(-R2)-C(=Y)-N(-N(-R5)-R6)-C(=Y)-N(-R3)-R4 M-(X)N

WHEREIN R1-R6 ARE EACH SELECTED FROM A GROUP CONSISTING OF HYDROGEN, C1-C10 ALKYL, C2-C10 ALKENYL, C3-C10 CYCLOALKYL OPTIONALLY SUBSTITUTED WITH C1-C6 ALKYL CHLORO, BROMO, C6-C10 ARYL, OPTIONALLY SUBSTITUTED WITH C1-C6 ALKYL, CHLORO, BROMO, C7-C10 ARYLALKYL, C7-C10 ALKARYL. R1 AND R6 AND/OR R3 AND R4 AND0OR R5 AND R6 TOGETHER CAN BE A CARBOCYLCLIC RING CONTAINING ONE OR MORE HETEROATOMS SUCH AS N OR S; M IS ONE SELECTED FROM THE GROUP CONSISTING OF ZINC, IRON, NICKEL, COPPER, MANGANESE AND COBALT; X IS AN ANION BEING ONE SELECTED FROM THE GROUP CONSISTING OF CHLORIDE, BROMIDE, IODIDE, SULFATE, NITRATE, PHOSPHATE AND ACETATE; N IS AN INTEGER DETERMINED BY THE VALENCE OF THE METAL ATOMS, AND Y IS EITHER O OR S.

74. 发明授权

US3625950A Certain halophenoxy alkanamides, hydrazides and derivatives thereof 失效
标题翻译：某些卤代烷氧基烷烃，其衍生物及其衍生物
公开(公告)号：US3625950A
公开(公告)日：1971-12-07
申请号：US3625950D
申请日：1968-07-03
申请人： MERCK & CO INC
发明人： CRAGOE EDWARD J JR , GOULD NORMAN P
IPC分类号： C07C59/68 , C07C273/18 , C07C275/50 , C07C279/22 , C07D213/77 , C07D233/44 , C07D295/185 , C07D521/00 , C07D31/44
CPC分类号： C07D213/77 , C07C59/68 , C07C273/1854 , C07C279/22 , C07D231/12 , C07D233/44 , C07D233/56 , C07D249/08 , C07D295/185 , Y10S514/866 , C07C275/50
摘要： The invention relates to omega , omega -dimethyl- omega (halophenoxy)-alkanamides, i.e., alkanamides bearing a halophenoxy and two methyl groups on the terminal carbon atom. The products are obtained by treating the corresponding omega , omega -dimethyl- omega -(halophenoxy)alkanoic acid ester or imidazole derivative thereof with an amine to form the desired amide. The said products are hypoglycemic agents, that is, they reduce the concentration of glucose in the blood.

75. 发明授权

US3330837A Substituted hydrazine derivatives and process for the manufacture thereof 失效
标题翻译：取代的肼衍生物及其制备方法
公开(公告)号：US3330837A
公开(公告)日：1967-07-11
申请号：US20895262
申请日：1962-07-10
申请人： HOFFMANN LA ROCHE
发明人： WERNER BOLLAG , HUGO GUTMANN , ADO KAISER , ALBERT LANGEMANN , MARCEL MULLER , PAUL ZELLER
IPC分类号： A61K31/00 , C07D213/77
CPC分类号： C07D213/77 , A61K31/00 , Y02P20/55

76. 发明申请

US20210015825A1 THERAMUTEIN MODULATORS 有权
公开(公告)号：US20210015825A1
公开(公告)日：2021-01-21
申请号：US17038353
申请日：2020-09-30
申请人： HMI Medical Innovations, LLC
发明人： Gerard M. Housey
IPC分类号： A61K31/5377 , C07D213/81 , C07D213/87 , C07D215/50 , C07D231/14 , C07D239/42 , C07D239/84 , C07D253/065 , C07D401/12 , C07D405/12 , C07D409/12 , G01N33/574 , C07D239/48 , C07C243/38 , C07D213/77 , C07D213/86 , C07D215/38 , C07D253/075 , C07D403/12 , G01N33/573 , A61K31/47 , A61K31/4709 , A61K31/505 , A61K31/506 , A61K31/53 , G01N33/50 , A61K31/166 , A61K31/175 , A61K31/195 , A61K31/27 , A61K31/415 , A61K31/4196 , A61K31/44 , A61K31/4436 , A61K31/444 , A61K31/495 , A61K31/517
摘要： This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of particular interest are inhibitors and activators of endogenous protein variants, encoded by genes which have mutated, which variants often arise or are at least first identified as having arisen following exposure to a chemical agent which is known to be an inhibitor or activator of the corresponding unmutated endogenous protein.

77. 发明授权

US10806738B2 Theramutein modulators 有权
公开(公告)号：US10806738B2
公开(公告)日：2020-10-20
申请号：US16656271
申请日：2019-10-17
申请人： HMI Medical Innovations, LLC
发明人： Gerard M. Housey
IPC分类号： A61K31/5377 , C07D213/81 , C07D213/87 , C07D215/50 , C07D231/14 , C07D239/42 , C07D239/84 , C07D253/065 , C07D401/12 , C07D405/12 , C07D409/12 , G01N33/574 , C07D239/48 , C07C243/38 , C07D213/77 , C07D213/86 , C07D215/38 , C07D253/075 , C07D403/12 , G01N33/573 , A61K31/47 , A61K31/4709 , A61K31/505 , A61K31/506 , A61K31/53 , G01N33/50 , A61K31/166 , A61K31/175 , A61K31/195 , A61K31/27 , A61K31/415 , A61K31/4196 , A61K31/44 , A61K31/4436 , A61K31/444 , A61K31/495 , A61K31/517
摘要： This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of particular interest are inhibitors and activators of endogenous protein variants, encoded by genes which have mutated, which variants often arise or are at least first identified as having arisen following exposure to a chemical agent which is known to be an inhibitor or activator of the corresponding unmutated endogenous protein.

78. 发明申请

US20180099945A1 PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS 审中-公开
公开(公告)号：US20180099945A1
公开(公告)日：2018-04-12
申请号：US15835795
申请日：2017-12-08
申请人： Dow AgroSciences LLC
发明人： Qiang YANG , Beth LORSBACH , Gary ROTH , Noormohamed M. NIYAZ , Jeffrey NISSEN , Ronald ROSS, JR. , Greg WHITEKER , Carl DeAMICIS , Kaitlyn GRAY , Yu ZHANG
IPC分类号： C07D401/04 , C07D213/77
CPC分类号： C07D401/04 , A01N43/40 , A01N43/56 , C07D213/77
摘要： The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.

79. 发明授权

US09580420B2 Process for the preparation of 4-(8-(2-chlorophenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)bicyclo[2.2.1]heptan-1-ol and novel intermediates therefor 有权
标题翻译：制备4-（8-（2-氯苯氧基） - [1,2,4]三唑并[4,3-a]吡啶-3-基）双环[2.2.1]庚-1-醇的方法和新颖的中间体
公开(公告)号：US09580420B2
公开(公告)日：2017-02-28
申请号：US14817352
申请日：2015-08-04
申请人： BRISTOL-MYERS SQUIBB COMPANY
发明人： Xinhua Qian , Keming Zhu , Joerg Deerberg , Wendy Wangying Yang , Kana Yamamoto , Matthew R. Hickey
IPC分类号： C07D213/77 , C07C35/29 , C07D471/04 , C07C29/00 , C07C51/29 , C07C61/13
CPC分类号： C07D471/04 , C07C29/00 , C07C35/29 , C07C51/29 , C07C61/13 , C07C2602/42 , C07D213/77
摘要： A process is provided for preparing 4-(8-(2-chlorophenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)bicyclo[2.2.1]heptan-1-ol and novel intermediates used in the process. The compound is a 11-beta hydroxysteroid dehydrogenase type I inhibitor which exhibits activity in the treatment of various metabolic diseases.
摘要翻译：提供了制备4-（8-（2-氯苯氧基） - [1,2,4]三唑并[4,3-a]吡啶-3-基）双环[2.2.1]庚-1-醇和在此过程中使用的新型中间体。该化合物是在治疗各种代谢疾病中表现出活性的11-β羟基类固醇脱氢酶I型抑制剂。

80. 发明申请

US20160332987A1 PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS 有权
公开(公告)号：US20160332987A1
公开(公告)日：2016-11-17
申请号：US15223142
申请日：2016-07-29
申请人： Dow AgroSciences LLC
发明人： Qiang YANG , Beth LORSBACH , Gary ROTH , Noormohamed M. NIYAZ , Jeffrey NISSEN , Ronald ROSS, JR. , Greg WHITEKER , Carl DeAMICIS , Kaitlyn GRAY , Yu ZHANG
IPC分类号： C07D401/04 , A01N43/56 , A01N43/40 , C07D213/77
CPC分类号： C07D401/04 , A01N43/40 , A01N43/56 , C07D213/77
摘要： The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式