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81. 发明申请

US20160354129A1 DEVICE FOR MIXING AND STORING POLYMETHYLMETHACRYLATE BONE CEMENT 审中-公开
标题翻译：用于混合和储存聚甲基丙烯酸甲酯骨水泥的装置
公开(公告)号：US20160354129A1
公开(公告)日：2016-12-08
申请号：US15171460
申请日：2016-06-02
申请人： Heraeus Medical GmbH
发明人： Sebastian VOGT , Thomas KLUGE
IPC分类号： A61B17/88 , A61L27/02 , A61L27/16 , B01F13/00 , B01F15/02
摘要： A device and methods mix polymethylmethacrylate bone cement and/or store the starting components of the bone cement. The device comprising: a cartridge with an internal space for mixing the bone cement that is closed on one side by means of a mobile dispensing plunger; a monomer container for a monomer liquid and/or a connector for attachment of a monomer container for a monomer liquid such that the monomer container can be opened appropriately in the device such that the monomer liquid flows from the monomer container into the device; a connecting conduit through which the monomer liquid can be guided into the internal space of the cartridge. A first hollow cylinder is connected to the connecting conduit and a second hollow cylinder is connected, via a vacuum conduit, to the internal space of the cartridge, whereby a pumping plunger is shiftable axially in the first hollow cylinder and is arranged in the first hollow cylinder and a vacuum plunger that is shiftable axially in the second hollow cylinder is arranged in the second hollow cylinder, whereby the pumping plunger and the vacuum plunger may be moved simultaneously.
摘要翻译：一种装置和方法混合聚甲基丙烯酸甲酯骨水泥和/或储存骨水泥的起始组分。所述装置包括：具有内部空间的药筒，所述内部空间用于混合通过移动分配柱塞在一侧封闭的骨粘固剂; 用于单体液体的单体容器和/或用于连接单体液体的单体容器的连接器，使得单体容器可以在装置中适当地打开，使得单体液体从单体容器流入装置; 连接导管，单体液体可以通过该导管引导到盒的内部空间中。第一中空圆筒连接到连接导管，第二中空圆筒经由真空导管连接到墨盒的内部空间，由此泵送柱塞在第一中空圆柱体中轴向移动并且布置在第一空心圆筒气缸和在第二中空圆柱体中可轴向移动的真空柱塞布置在第二中空圆柱体中，由此泵送柱塞和真空柱塞可以同时移动。

82. 发明申请

US20160332328A1 SPACER MOULD AND METHOD FOR PRODUCING HIP SPACERS 审中-公开
标题翻译：间隔模具及其生产方法
公开(公告)号：US20160332328A1
公开(公告)日：2016-11-17
申请号：US15079096
申请日：2016-03-24
申请人： Heraeus Medical GmbH
发明人： Edgar Wüst , Sebastian VOGT
IPC分类号： B28B7/00 , A61F2/36 , B28B23/02 , A61F2/30 , B28B7/14 , B28B3/02
CPC分类号： B28B7/0097 , A61F2/3094 , A61F2/30942 , A61F2/36 , A61F2/3672 , A61F2002/30616 , A61F2002/30672 , A61F2002/30693 , A61F2002/30957 , A61F2310/00353 , B28B3/02 , B28B7/14 , B28B23/02
摘要： A spacer mould and method for producing a hip spacer, the spacer mould comprises a base element (1), in which a hollow mould is provided as negative image of one side of a femoral stem of the spacer to be generated, whereby a recess connected to the hollow mould is arranged on the proximal end of the hollow mould in the base element. The spacer mould further comprises a semi-spherical insert (2) comprising a femoral head mould as negative image of one side of a femoral head of the spacer to be generated, whereby the semi-spherical insert (2) is to be arranged in the recess in the base element (1). Further, the spacer mould comprises an adapter insert (3) that is designed as a hollow body that is open on two sides and that is or can be arranged in the recess of the base element (1) between the semi-spherical insert (2) and the hollow mould such that the recess exerts a pressure onto the adapter insert (3) and the semi-spherical insert (2). Moreover, the spacer mould comprises a punch (4) that comprises a punch hollow mould in the form of the negative image of the remaining femoral stem and that is arranged on or can be pressed onto the top side of the base element (1).
摘要翻译：一种间隔模具及其制造方法，所述间隔模具包括基体元件（1），其中设置中空模具作为要产生的间隔件的股骨柄的一侧的负像，由此连接凹部在中空模具的基端部配置有空心模具。间隔模具还包括半球形插入件（2），其包括股骨头模具作为要产生的间隔件的股骨头的一侧的负像，由此半球形插入件（2）将被布置在在基部元件（1）中的凹部。此外，间隔模具包括适配器插入件（3），该适配器插入件被设计为在两侧敞开的中空体，并且该基座元件（1）的凹部中或可布置在半球状插入件（2））和中空模具，使得凹部对适配器插入件（3）和半球形插入件（2）施加压力。此外，间隔模具包括冲头（4），该冲头（4）包括形成剩余股骨柄的负像形式的冲头中空模具，并且被布置在基座元件（1）的顶侧上或可被压在基体元件（1）的顶侧上。

83. 发明授权

US09408944B2 Paste-like bone cement 有权
标题翻译：糊状骨水泥
公开(公告)号：US09408944B2
公开(公告)日：2016-08-09
申请号：US13949511
申请日：2013-07-24
申请人： Heraeus Medical GmbH
发明人： Sebastian Vogt
IPC分类号： A61L24/04 , A61L27/46 , A61L24/00
CPC分类号： A61L24/043 , A61L24/0073 , A61L24/0084 , A61L24/0089 , A61L27/46 , A61L2430/02 , C08L33/08
摘要： A paste contains at least one monomer for radical polymerization, at least one polymer that is soluble in said at least one monomer for radical polymerization, and at least one filling agent that is poorly soluble or insoluble in said at least one monomer for radical polymerization. The filling agent is a particulate inorganic calcium salt comprising the following properties: at least 90% by weight of the particulate inorganic calcium salt have a particle size of less than 63 μm, as determined by means of sieve analysis; and the solubility in water of the particulate inorganic calcium salt at 20° C. is less than 8.5 g per liter. A kit and the paste is usable for mechanical fixation of articular endoprostheses, for covering skull defects, for filling bone cavities, for femuroplasty, for vertebroplasty, for kyphoplasty, for the manufacture of spacers or for the production of carrier materials for local antibiotics therapy, as well as a form body.
摘要翻译：糊剂含有至少一种用于自由基聚合的单体，至少一种可溶于所述至少一种用于自由基聚合的单体的聚合物，以及至少一种难溶于或不溶于所述至少一种用于自由基聚合的单体的填充剂。填充剂是一种颗粒状无机钙盐，其包括以下性质：通过筛分分析确定的至少90重量％的颗粒状无机钙盐的粒度小于63μm; 并且在20℃下颗粒状无机钙盐在水中的溶解度小于8.5g /升。试剂盒和糊剂可用于关节内假体的机械固定，用于覆盖颅骨缺损，用于填充骨腔，用于股骨成形术，用于椎体成形术，椎体后凸成形术，用于制造间隔件或用于生产用于局部抗生素治疗的载体材料，以及表单。

84. 发明授权

US09339317B2 Mixing device for prepack vacuum cementing system, vacuum cementing system, and method 有权
标题翻译：预制真空胶合系统混合装置，真空固井系统及方法
公开(公告)号：US09339317B2
公开(公告)日：2016-05-17
申请号：US13822546
申请日：2011-08-10
申请人： Sebastian Vogt , Hubert Buechner
发明人： Sebastian Vogt , Hubert Buechner
IPC分类号： B01F13/06 , A61B17/88 , B01F7/00 , B01F13/00 , B01F15/00 , B01F15/02 , B29B7/10 , B01F7/16
CPC分类号： A61B17/88 , A61B17/8822 , A61B17/8827 , B01F7/007 , B01F7/00716 , B01F7/16 , B01F13/0018 , B01F15/00071 , B01F15/00506 , B01F15/00798 , B01F15/00974 , B01F15/0278 , B29B7/10
摘要： A mixing device, for a mixable material, has at least one cartridge and a closure piece. The cartridge contains a first component of the mixable material and has a cartridge head in which at least one air opening is arranged, and the closure piece is arranged on the cartridge head in such a way that the at least one air opening in the cartridge head can be closed and opened by the closure piece. The closure piece is mounted so as to be rotatable or slideable relative to the cartridge head, and a connection extends through the cartridge head or a cartridge wall into the interior of the cartridge and connects the interior of the cartridge to a container for a second component of the mixable material.
摘要翻译：用于可混合材料的混合装置具有至少一个筒和封闭件。墨盒包含可混合材料的第一部件，并且具有墨盒头，其中布置有至少一个空气开口，并且封闭件以这样的方式设置在盒头部上，使得盒头中的至少一个空气开口可以由封闭件封闭并打开。封闭件安装成相对于盒头可旋转或可滑动，并且连接件通过盒头或盒壁延伸到盒的内部，并将盒的内部连接到用于第二部件的容器的可混合材料。

85. 发明授权

US09272803B2 Vacuum cementing system 有权
标题翻译：真空固井系统
公开(公告)号：US09272803B2
公开(公告)日：2016-03-01
申请号：US13808452
申请日：2011-06-10
申请人： Sebastian Vogt , Hubert Buechner , Tim Schnieber
发明人： Sebastian Vogt , Hubert Buechner , Tim Schnieber
IPC分类号： B65B69/00 , A61B17/88 , B01F11/00 , B01F13/00 , B01F15/02 , A61F2/30 , A61F2/46
CPC分类号： B65B69/00 , A61B17/8833 , A61F2002/30561 , A61F2002/4685 , B01F11/0082 , B01F13/0023 , B01F15/0206 , B01F15/0258 , B65B69/0008
摘要： A vacuum cementing system has at least one cement powder cartridge and a container-opening system. The container-opening system has at least one container for at least one liquid and/or at least one powder, an opening device, and an outlet opening for applying a negative pressure. When a negative pressure is being applied, the opening device is mobile relative to at least a part of the at least one container. The vacuum cementing system has a means for connecting the cement powder cartridge to the at least one container and utilizes necessary vacuum for automatically opening the at least one container.
摘要翻译：真空固井系统具有至少一个水泥粉末盒和容器开启系统。容器开启系统具有用于至少一种液体和/或至少一种粉末，开启装置和用于施加负压的出口开口的至少一个容器。当施加负压时，打开装置相对于至少一个容器的至少一部分是可移动的。真空固井系统具有用于将水泥粉末筒连接到至少一个容器并利用必要的真空来自动打开至少一个容器的装置。

86. 发明申请

US20160045243A1 VACUUM CEMENTING SYSTEM 审中-公开
公开(公告)号：US20160045243A1
公开(公告)日：2016-02-18
申请号：US14923970
申请日：2015-10-27
申请人： Heraeus Medical GmbH
发明人： Sebastian Vogt , Hubert Buechner , Tim Schnieber
IPC分类号： A61B17/88
CPC分类号： B65B69/00 , A61B17/8833 , A61F2002/30561 , A61F2002/4685 , B01F11/0082 , B01F13/0023 , B01F15/0206 , B01F15/0258 , B65B69/0008
摘要： A vacuum cementing system has at least one cement powder cartridge and a container-opening system. The container-opening system has at least one container for at least one liquid and/or at least one powder, an opening device, and an outlet opening for applying a negative pressure. When a negative pressure is being applied, the opening device is mobile relative to at least a part of the at least one container. The vacuum cementing system has a means for connecting the cement powder cartridge to the at least one container and utilizes necessary vacuum for automatically opening the at least one container.

87. 发明授权

US09233188B2 Polymethylmethacrylate bone cement 有权
标题翻译：聚甲基丙烯酸甲酯骨水泥
公开(公告)号：US09233188B2
公开(公告)日：2016-01-12
申请号：US14078568
申请日：2013-11-13
申请人： HERAEUS HOLDING GMBH
发明人： Sebastian Vogt
IPC分类号： A61L24/06 , A61L27/16
CPC分类号： A61L24/06 , A61L27/16 , A61L2430/02 , C08L33/10
摘要： The subject matter of the invention is a curable composition for use as bone cement, in particular for augmentation of osteoporotic bone tissue, comprising at least one organic polymer and at least one monomer for radical polymerization, at least one particulate inorganic additive having a BET surface of at least 40 m2/g, whereby the additive comprises covalently bound hydroxyl groups, whereby the composition further comprises at least one fatty acid ester or a mixture of fatty acid esters. Another subject matter of the invention is the use of said composition for augmentation of osteoporotic bone tissue and particularly preferably for vertebroplasty, kyphoplasty, and augmentation of drill holes in osteoporotic bone tissue, as well as a kit for producing said composition.
摘要翻译：本发明的主题是用作骨水泥的可固化组合物，特别是用于增加骨质疏松性骨组织，包含至少一种有机聚合物和至少一种用于自由基聚合的单体，至少一种具有BET表面的颗粒状无机添加剂至少40m 2 / g，由此所述添加剂包括共价结合的羟基，其中所述组合物还包含至少一种脂肪酸酯或脂肪酸酯的混合物。本发明的另一个主题是所述组合物用于增加骨质疏松性骨组织，特别优选用于椎体成形术，脊柱后凸成形术和骨质疏松性骨组织中钻孔的增加，以及用于制备所述组合物的试剂盒。

88. 发明授权

US09220853B2 Lavage system having a nozzle 有权
标题翻译：灌洗系统具有喷嘴
公开(公告)号：US09220853B2
公开(公告)日：2015-12-29
申请号：US13873675
申请日：2013-04-30
申请人： Heraeus Medical GmbH
发明人： Sebastian Vogt
IPC分类号： A61M11/00 , A61M11/02 , B05B7/24 , B05B15/02 , B05B15/04 , A61M1/00 , A61M3/02 , B05B7/12 , B05B12/00 , A61B17/00
CPC分类号： A61M11/02 , A61B2017/0023 , A61M1/0064 , A61M3/0233 , A61M3/0283 , B05B7/12 , B05B7/2421 , B05B7/2435 , B05B12/002 , B05B14/30 , B05B15/50
摘要： A medical spray device has a compressed gas supply conduit for guiding a gas flow, a liquid supply conduit for supplying a liquid, a dispensing tube having an open tube end for spraying fine droplets or a spray mist of a liquid-gas mixture, and an operable valve element that is arranged in the compressed gas supply conduit. A constriction of the cross-sectional area is provided in the dispensing tube and a merging site is arranged in the region of the constriction through which the liquid merges into the gas flow from the compressed gas supply conduit, whereby the constriction forms a nozzle in the dispensing tube. A spray device kit provides a medical spray device, a gas supply conduit, a pressure regulator, and a compressed gas container.
摘要翻译：医用喷雾装置具有用于引导气流的压缩气体供给管道，用于供给液体的液体供给管道，具有用于喷射细小液滴的开口端部或液体 - 气体混合物的喷雾的分配管，以及布置在压缩气体供应管道中的可操作阀元件。在分配管中设置横截面积的缩小部，并且在收缩部的区域配置合流部位，液体从压缩气体供给管汇合到气体流中，由此收缩部在分配管。喷雾装置套件提供医疗喷雾装置，气体供应管道，压力调节器和压缩气体容器。

89. 发明申请

US20150367301A1 VACUUM MIXING SYSTEM AND METHOD FOR THE MIXING OF POLYMETHYLMETHACRYLATE BONE CEMENT 审中-公开
标题翻译：真空混合系统及混合聚甲基丙烯酸甲酯骨水泥的方法
公开(公告)号：US20150367301A1
公开(公告)日：2015-12-24
申请号：US14734157
申请日：2015-06-09
申请人： HERAEUS MEDICAL GMBH
发明人： Sebastian VOGT
IPC分类号： B01F13/06 , B01F3/12 , B01F13/00 , B01F15/02
CPC分类号： B01F13/065 , B01F3/1214 , B01F3/1271 , B01F11/0082 , B01F13/0023 , B01F13/0033 , B01F13/06 , B01F15/0201 , B01F15/0206 , B01F15/0258 , B01F15/0278 , B01F15/0279 , B01F2215/0029 , F04B33/00
摘要： A vacuum mixing system for the mixing of polymethylmethacrylate bone cement, comprising at least one cartridge (4) having an evacuable internal space for mixing of the bone cement, a pump (18) for generating a negative pressure, and a connecting conduit (12) connecting the internal space of the at least one cartridge (4) to the pump (18) for generating a negative pressure, an integrated energy reservoir (28) for driving the pump (18) that is or can be connected to the pump (18) and has energy for at least one pumping process of the pump (18) stored in it, whereby a negative pressure can be generated by means of the pump (18) during the pumping process, which negative pressure can be used to evacuate gas from the internal space of the at least one cartridge (4) through the connecting conduit (12).
摘要翻译：一种用于混合聚甲基丙烯酸甲酯骨水泥的真空混合系统，包括至少一个具有用于混合骨水泥的可抽空内部空间的筒（4），用于产生负压的泵（18）和连接导管（12）将所述至少一个盒（4）的内部空间连接到所述泵（18）以产生负压;用于驱动所述泵（18）的集成能量储存器（28），所述泵（18）可以或可以连接到所述泵（18 ）并且具有用于储存在其中的泵（18）的至少一个泵送过程的能量，由此在泵送过程期间可以通过泵（18）产生负压，该负压可以用于将气体从所述至少一个盒（4）的内部空间通过所述连接导管（12）。

90. 发明授权

US09126750B2 Dispensing device for flowable materials 有权
标题翻译：可流动材料分配装置
公开(公告)号：US09126750B2
公开(公告)日：2015-09-08
申请号：US14029979
申请日：2013-09-18
申请人： Heraeus Medical GmbH
发明人： Sebastian Vogt , Clemens Greiner , Rudolf Hein
IPC分类号： B65D83/66 , A61B17/88 , B05C17/015
CPC分类号： B65D83/66 , A61B17/8822 , B05C17/015
摘要： A dispensing device dispenses flowable materials from cartridges, whereby the dispensing device comprises a base body, a connecting element for a gas cartridge on the base body, a valve element for controlling a gas flow from the gas cartridge, and a gas-permeable channel connecting the connecting element to the valve element. At least one evaporation container is arranged in the gas-permeable channel such that the gas flow from the gas cartridge is guided through the evaporation container, at least over regions thereof.
摘要翻译：分配装置从盒中分配可流动材料，由此分配装置包括基体，用于基体上的气体盒的连接元件，用于控制来自气体盒的气流的阀元件，以及连接连接元件到阀元件。至少一个蒸发容器布置在透气通道中，使得来自气筒的气流至少在其上的区域被引导通过蒸发容器。

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