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1. 发明授权

US08116865B2 Defibrillation shock output circuit 有权
标题翻译：除颤电击输出电路
公开(公告)号：US08116865B2
公开(公告)日：2012-02-14
申请号：US12332497
申请日：2008-12-11
申请人： William J. Linder , Hari Sree
发明人： William J. Linder , Hari Sree
IPC分类号： A61N1/39
CPC分类号： A61N1/3918 , A61N1/36185 , A61N1/3686 , A61N1/3688
摘要： This document discusses, among other things, techniques for generating and delivering a high voltage defibrillation shock using an implantable cardiac rhythm management device. An output energy delivery bridge can be programmed to provide desired shock vectors or polarities. A bootstrapped fully solid-state switch control voltage generation circuit is described. Automatic polarity or vector reconfiguration embodiments are described, such as in response to an unsuccessful attempt to convert the heart to a normal rhythm.
摘要翻译：本文件尤其涉及使用可植入式心律管理装置产生和递送高压除颤电击的技术。输出能量输送桥可以被编程以提供期望的震动矢量或极性。描述了自举完全固态开关控制电压产生电路。描述了自动极性或向量重新配置实施例，例如响应于将心脏转换成正常节奏的不成功的尝试。

2. 发明授权

US07996086B2 Apparatus and method for pacing mode switching during atrial tachyarrhythmias 有权
标题翻译：在房性快速性心律失常中起搏模式切换的装置和方法
公开(公告)号：US07996086B2
公开(公告)日：2011-08-09
申请号：US12891669
申请日：2010-09-27
申请人： Jeffrey E. Stahmann , Andrew P. Kramer
发明人： Jeffrey E. Stahmann , Andrew P. Kramer
IPC分类号： A61N1/00
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3684
摘要： A method for operating a cardiac pacemaker in which the mode of operation of the pacemaker is altered in response to detecting an episode of atrial tachycardia. In accordance with the invention, the pacemaker's pacing mode is altered in a manner that attempts to maintain hemodynamic stability during the atrial tachycardia. Such a mode switch is particularly applicable to pacemaker patients suffering from some degree of congestive heart failure.
摘要翻译：一种用于操作心脏起搏器的方法，其中起搏器的操作模式响应于检测心房心动过速的发作而改变。根据本发明，起搏器的起搏模式以在心房心动过速期间维持血液动力学稳定性的方式改变。这种模式切换特别适用于患有某种程度充血性心力衰竭的起搏器患者。

3. 发明授权

US09393426B2 Systems and methods for ranking and selection of pacing vectors 有权
标题翻译：起搏向量的排序和选择的系统和方法
公开(公告)号：US09393426B2
公开(公告)日：2016-07-19
申请号：US14520559
申请日：2014-10-22
申请人： Cardiac Pacemakers, Inc.
发明人： Krzysztof Z. Siejko , Shibaji Shome , Jiang Ding
IPC分类号： A61N1/37 , A61N1/05 , A61N1/36 , A61N1/365 , A61N1/368
CPC分类号： A61N1/3704 , A61N1/056 , A61N1/36185 , A61N1/36514 , A61N1/36542 , A61N1/36585 , A61N1/368 , A61N1/3686 , A61N1/371
摘要： Approaches to rank potential left ventricular (LV) pacing vectors are described. Early elimination tests are performed to determine the viability of LV cathode electrodes. Some LV cathodes are eliminated from further testing based on the early elimination tests. LV cathodes identified as viable cathodes are tested further. Viable LV cathode electrodes are tested for hemodynamic efficacy. Cardiac capture and phrenic nerve activation thresholds are then measured for potential LV pacing vectors comprising a viable LV cathode electrode and an anode electrode. The potential LV pacing vectors are ranked based on one or more of the hemodynamic efficacy of the LV cathodes, the cardiac capture thresholds, and the phrenic nerve activation thresholds.
摘要翻译：描述了评估潜在的左心室（LV）起搏向量的方法。执行早期消除测试以确定LV阴极的可行性。基于早期消除测试，一些LV阴极被进一步测试消除。确定为阴极的LV阴极被进一步测试。测试可行的LV阴极电极的血液动力学效能。然后测量包含可行的LV阴极电极和阳极电极的潜在LV起搏向量的心脏捕获和膈神经激活阈值。潜在的LV起搏向量基于LV阴极的血液动力学功效，心脏捕获阈值和膈神经激活阈值中的一种或多种进行排名。

4. 发明授权

US09242107B2 Seal plug 有权
标题翻译：密封塞
公开(公告)号：US09242107B2
公开(公告)日：2016-01-26
申请号：US14309866
申请日：2014-06-19
申请人： Cardiac Pacemakers, Inc.
发明人： Daragh Nolan , James M. English , John O'Rourke , Sean Walsh
IPC分类号： A61N1/00 , A61N1/375 , A61N1/362 , H01R13/52 , H01R4/36
CPC分类号： A61N1/3752 , A61N1/362 , H01R4/36 , H01R13/5224 , Y10T29/49885
摘要： An implantable pulse generator includes a core assembly, a seal plug, and an outer layer overmolded over the core assembly adjacent the seal plug. The core assembly defines a core hole extending through the core assembly from a core interior to a core outer surface. The core hole has a hole outer portion and a hole inner portion. A first diameter of the hole outer portion is less than a second diameter of the hole inner portion. The seal plug is positioned in the core hole and has a plug outer portion aligned with the hole outer portion and a plug inner portion aligned with the hole inner portion. A third diameter of the plug outer portion is less than a fourth diameter of the plug inner portion. The outer layer leaves a top of the seal plug exposed.
摘要翻译：可植入式脉冲发生器包括芯组件，密封塞和外围模制在芯组件上的外层，邻近密封塞。芯组件限定了从芯部内部到芯部外表面延伸穿过芯组件的芯孔。芯孔具有孔外部部分和孔内部部分。孔外部的第一直径小于孔内部的第二直径。密封塞定位在芯孔中，并且具有与孔外部对准的插头外部部分和与孔内部对准的插头内部。插头外部的第三直径小于插头内部的第四直径。外层留下暴露的密封塞的顶部。

5. 发明授权

US09242113B2 Modular antitachyarrhythmia therapy system 有权
公开(公告)号：US09242113B2
公开(公告)日：2016-01-26
申请号：US14639426
申请日：2015-03-05
申请人： CARDIAC PACEMAKERS, INC.
发明人： Joseph M. Smith , Richard Milton Dujmovic, Jr.
IPC分类号： A61N1/00 , A61N1/39 , A61N1/372 , A61N1/362 , A61N1/365 , A61N1/36 , A61N1/375
CPC分类号： A61N1/3962 , A61N1/3605 , A61N1/3621 , A61N1/3622 , A61N1/36514 , A61N1/36564 , A61N1/36585 , A61N1/372 , A61N1/37217 , A61N1/3756 , A61N1/3925 , A61N1/3956 , A61N1/3987
摘要： This document discusses, among other things, a modular antitachyarrhythmia therapy system. In an example, a modular antitachyarrhythmia system includes at least two separate modules that coordinate delivery an antitachyarrhythmia therapy, such as defibrillation therapy. In another example, a modular antitachyarrhythmia therapy system includes a sensing module, an analysis module, and a therapy module.

6. 发明授权

US09242099B2 Cardiac rhythm management system selecting between multiple same-chamber electrodes for delivering cardiac therapy 有权
公开(公告)号：US09242099B2
公开(公告)日：2016-01-26
申请号：US14090713
申请日：2013-11-26
申请人： Cardiac Pacemakers, Inc.
发明人： Jiang Ding , Julio C. Spinelli , Andrew P. Kramer
IPC分类号： A61N1/368 , A61N1/362
CPC分类号： A61N1/3684 , A61N1/3627 , A61N1/36514 , A61N1/368
摘要： A cardiac rhythm management system selects one of multiple electrodes associated with a particular heart chamber based on a relative timing between detection of a depolarization fiducial point at the multiple electrodes, or based on a delay between detection of a depolarization fiducial point at the multiple electrodes and detection of a reference depolarization fiducial point at another electrode associated with the same or a different heart chamber. Subsequent contraction-evoking stimulation therapy is delivered from the selected electrode.

7. 发明授权

US08983626B2 Stimulation cuff and implantation tool 有权
标题翻译：刺激袖口和植入工具
公开(公告)号：US08983626B2
公开(公告)日：2015-03-17
申请号：US14141702
申请日：2013-12-27
申请人： Cardiac Pacemakers, Inc.
发明人： Paul E. Zarembo , Bruce A. Tockman
IPC分类号： A61N1/05
CPC分类号： A61N1/0556
摘要： Various embodiments concern wrapping a stimulation cuff around a nerve. The cuff can comprise a main body and at least one electrode. The main body can comprise an inner tab, an outer tab, and an intermediate portion extending between the inner tab and the outer tab, the at least one electrode disposed on the intermediate portion, the main body biased such that the cuff assumes the coiled arrangement. The cuff can be uncoiled by pulling on a first elongate element attached to a first tubular member, the first tubular member encircled within the cuff. The nerve can be engaged with an inner surface of the main body along the intermediate portion while the inner tab is releaseably attached to the first elongate element. The first elongate element can be released to allow the cuff to wrap around the nerve.
摘要翻译：各种实施例涉及在神经周围包裹刺激袖带。袖带可以包括主体和至少一个电极。主体可以包括内部突片，外部突片和在内部突片和外部突出部之间延伸的中间部分，所述至少一个电极设置在中间部分上，主体被偏压使得袖带呈现卷绕的布置。通过拉动附接到第一管状构件的第一细长元件可以展开袖带，第一管状构件环绕在袖带内。神经可以沿着中间部分与主体的内表面接合，而内突片可释放地附接到第一细长元件。可以释放第一细长元件以允许袖带包裹在神经周围。

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