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1. 发明申请

US20190217107A1 AUTOMATIC CURRENT BALANCING WITH LOCK CONTROL FOR A CLINICIAN PROGRAMMER 审中-公开
公开(公告)号：US20190217107A1
公开(公告)日：2019-07-18
申请号：US16191392
申请日：2018-11-14
申请人： Nuvectra Corporation
发明人： Norbert Kaula , Yohannes Iyassu
IPC分类号： A61N1/372 , A61N1/36 , G16H40/63 , G06F3/0484 , G06F3/0485 , G16H50/50
CPC分类号： A61N1/37247 , A61N1/36185 , G06F3/0482 , G06F3/0484 , G06F3/04842 , G06F3/04847 , G06F3/0485 , G06F19/00 , G06F19/3481 , G16H20/30 , G16H40/63 , G16H50/50
摘要： A first fraction of an electrical stimulation is allocated to a first electrode. In response to user input, the first fraction of the electrical stimulation is fixed to the first electrode such that the first fraction is user-adjustable but cannot be automatically changed. In response to the first fraction being fixed to the first electrode, a respective second fraction of the electrical stimulation is automatically allocated to a plurality of second electrodes. The second fraction is a function of the first fraction and a total number of the second electrodes. Thereafter, a new electrode is added to, or deleting from, the second electrodes, while the first fraction is still fixed to the first electrode. The respective second fractions are automatically adjusted in response to the adding or the deleting, without affecting the first fraction of the electrical stimulation that has been fixed to the first electrode.

2. 发明申请

US20190209849A1 METHODS AND SYSTEMS FOR STIMULATION FOR GLIAL MODULATION 审中-公开
公开(公告)号：US20190209849A1
公开(公告)日：2019-07-11
申请号：US16242461
申请日：2019-01-08
申请人： Boston Scientific Neuromodulation Corporation
发明人： Bradley Lawrence Hershey , Tianhe Zhang , Natalie A. Brill , Rosana Esteller , Jianwen Gu
IPC分类号： A61N1/372 , A61N1/36
CPC分类号： A61N1/37247 , A61N1/36062 , A61N1/36185
摘要： A system for planning or conducting stimulation includes a display; and a processor that executes instructions configured for: displaying, on the display, a representation of a stimulation effect; obtaining and displaying, on the display, a path for migration of the stimulation effect; receiving a duration or rate for migration of the stimulation effect; and determining a selection of one of more electrodes or optical stimulators for one or more stimulation leads of a stimulation system to produce the stimulation effect and conduct the migration of the stimulation effect along the path according to the duration or rate.

3. 发明申请

US20190209844A1 Automatic Adjustment of Sub-Perception Therapy in an Implantable Stimulator Using Detected Compound Action Potentials 审中-公开
公开(公告)号：US20190209844A1
公开(公告)日：2019-07-11
申请号：US16238151
申请日：2019-01-02
申请人： Boston Scientific Neuromodulation Corporation
发明人： Rosana Esteller , Rafael Carbunaru
IPC分类号： A61N1/36
CPC分类号： A61N1/36164 , A61N1/0534 , A61N1/0551 , A61N1/36071 , A61N1/36132 , A61N1/36139 , A61N1/36178 , A61N1/36185 , A61N1/37247 , A61N1/3758
摘要： Medical device systems and methods for providing spinal cord stimulation (SCS) are disclosed. The SCS systems and methods provide therapy below the perception threshold of the patient. The methods and systems are configured to measure neurological responses to stimulation and use the neurological responses as biomarkers to maintain and adjust therapy. An example of neurological responses includes an evoked compound action potential (ECAP).

4. 发明申请

US20190184183A1 POINT-AND-CLICK PROGRAMMING FOR DEEP BRAIN STIMULATION USING REAL-TIME MONOPOLAR REVIEW TRENDLINES 审中-公开
公开(公告)号：US20190184183A1
公开(公告)日：2019-06-20
申请号：US16284917
申请日：2019-02-25
申请人： Boston Scientific Neuromodulation Corporation
发明人： Stephen Carcieri , Dean Chen , Michael A. Moffitt
IPC分类号： A61N1/372 , A61N1/36 , G16H40/63 , A61N1/05
CPC分类号： A61N1/37247 , A61N1/0534 , A61N1/3605 , A61N1/36082 , A61N1/36185 , A61N1/372 , G06F19/00 , G16H40/63
摘要： A system and method for selecting leadwire stimulation parameters includes a processor iteratively performing, for each of a plurality of values for a particular stimulation parameter, each value corresponding to a respective current field: (a) shifting the current field longitudinally and/or rotationally to a respective plurality of locations about the leadwire; and (b) for each of the respective plurality of locations, obtaining clinical effect information regarding a respective stimulation of the patient tissue produced by the respective current field at the respective location; and displaying a graph plotting the clinical effect information against values for the particular stimulation parameter and locations about the leadwire, and/or based on the obtained clinical effect information, identifying an optimal combination of a selected value for the particular stimulation parameter and selected location about the leadwire at which to perform a stimulation using the selected value.

5. 发明申请

US20190083788A1 Multilayer supporting structure for subsurface electrodes for electric field shaping 审中-公开
公开(公告)号：US20190083788A1
公开(公告)日：2019-03-21
申请号：US16177309
申请日：2018-10-31
申请人： Daisong Zhang , Sergio Lara Pereira Monteiro
发明人： Daisong Zhang , Sergio Lara Pereira Monteiro
IPC分类号： A61N1/368 , A61N1/02 , A61N1/36 , A61N1/05 , A61N1/372
CPC分类号： A61N1/3686 , A61N1/025 , A61N1/0529 , A61N1/0565 , A61N1/36185 , A61N1/372
摘要： An electric stimulator for heart (as in heart pacemakers), brain (as in DBS), organs and general cells, with a supporting structure where there exists a plurality of electrically isolated electrodes called passive electrodes or field-shaping electrodes that are located under the surface of the supporting structure. The passive electrodes are controlled by an appropriate electronics control unit and powered by some electric energy storage, as a battery. Passive or field-shaping electrodes are electrically insulated, being unable to inject current in the surrounding medium, but they are capable of shaping the electric field in the space surrounding the electrodes, which has consequence on the path of the stimulating currents injected by other devices or by the organism itself. The invention also discloses locating the passive electrodes at different depths from the surface of the supporting structure.

6. 发明申请

US20180369591A1 ELECTRODE SELECTION FOR SUB-THRESHOLD MODULATION THERAPY 审中-公开
公开(公告)号：US20180369591A1
公开(公告)日：2018-12-27
申请号：US16119560
申请日：2018-08-31
申请人： Boston Scientific Neuromodulation Corporation
发明人： Dongchul Lee , Changfang Zhu
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61N1/36164 , A61N1/36071 , A61N1/36132 , A61N1/36139 , A61N1/36178 , A61N1/36185 , A61N1/37247
摘要： A neuromodulation system and method of providing sub-threshold therapy to a patient. An anodic perception threshold of super-threshold electrical energy and a cathodic perception threshold of super-threshold electrical energy are determined for a plurality of electrode sets. A ratio between the anodic perception threshold and the cathodic perception threshold is calculated for each of the electrode sets. An effective electrode set is selected based on the ratio between the anodic perception threshold and the cathodic perception threshold.

7. 发明申请

US20180345024A1 METHOD AND APPARATUS TO PERFORM ELECTRODE COMBINATION SELECTION 审中-公开
公开(公告)号：US20180345024A1
公开(公告)日：2018-12-06
申请号：US16012416
申请日：2018-06-19
申请人： Cardiac Pacemakers, Inc.
发明人： M. Jason Brooke , Andrea E. Acuna
IPC分类号： A61N1/37
CPC分类号： A61N1/3708 , A61N1/36185 , A61N1/3627 , A61N1/3684 , A61N1/3686 , A61N1/37 , A61N1/3706 , A61N1/371 , A61N1/37211 , A61N1/37241 , A61N1/3962
摘要： The present invention involves approaches for selecting one or more electrode combinations. Various method embodiments can include implanting a plurality of cardiac electrodes supported by one or more leads in a patient, attaching the one or more leads to a patient external analyzer circuit, delivering electrical stimulation to the patient's heart using the plurality of cardiac electrodes and the analyzer circuit, evaluating, for each electrode combination of a plurality of electrode combinations of the plurality of cardiac electrodes, one or more first parameters and one or more second parameters produced by the electrical stimulation delivered using the electrode combination, the first parameters supportive of cardiac function consistent with a prescribed therapy and the second parameters not supportive of cardiac function consistent with the prescribed therapy, selecting one or more electrode combinations of the plurality of cardiac electrodes based on the evaluation, the one or more electrode combinations selected as being associated with the one or more first parameters and less associated with the one or more second parameters relative to other electrode combinations of the plurality of cardiac electrodes, programming an implantable pacing circuit to deliver a cardiac pacing therapy that preferentially uses the selected one or more electrode combinations relative to other electrode combinations of the plurality of cardiac electrodes, detaching the one or more leads from the analyzer circuit, attaching the one or more leads to the implantable pacing circuit, and implanting the implantable pacing circuit.

8. 发明申请

US20180345007A1 Architectures for Multi-Electrode Implantable Stimulator Devices Having Minimal Numbers of Decoupling Capacitors 审中-公开
公开(公告)号：US20180345007A1
公开(公告)日：2018-12-06
申请号：US16102302
申请日：2018-08-13
申请人： Boston Scientific Neuromodulation Corporation
发明人： Jordi Parramon , Rafael Carbunaru
IPC分类号： A61N1/05 , A61N1/36 , A61N1/368 , A61N1/372
CPC分类号： A61N1/05 , A61N1/36125 , A61N1/36185 , A61N1/3686 , A61N1/37205
摘要： Architectures for implantable stimulators having N electrodes are disclosed. The architectures contains X current sources, or DACs. In a single anode/multiple cathode design, one of the electrodes is designated as the anode, and up to X of the electrodes can be designated as cathodes and independently controlled by one of the X DACs, allowing complex patient therapy and current steering between electrodes. The design uses at least X decoupling capacitors: X capacitors in the X cathode paths, or one in the anode path and X−1 in the X cathode paths. In a multiple anode/multiple cathode design having X DACs, a total of X−1 decoupling capacitors are needed. Because the number of DACs X can typically be much less than the total number of electrodes (N), these architectures minimize the number of decoupling capacitors which saves space, and ensures no DC current injection even during current steering.

9. 发明申请

US20180339156A1 APPARATUS AND METHODS FOR ASSISTED BREATHING BY TRANSVASCULAR NERVE STIMULATION 审中-公开
公开(公告)号：US20180339156A1
公开(公告)日：2018-11-29
申请号：US15606867
申请日：2017-05-26
申请人： Lungpacer Medical Inc.
发明人： John E. NASH , Douglas G. EVANS , Viral THAKKAR
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/3611 , A61N1/0551 , A61N1/36185
摘要： A catheter may include an outer layer defining a plurality of apertures therethrough, and a body defining at least one longitudinal lumen therein. The body may be within the outer layer, and the apertures may be radially outward of the lumen. The catheter may also include a plurality of electrodes positioned in or on the catheter, with each electrode being electrically exposed through an aperture of the plurality of apertures. A ribbon cable may extend through the lumen and include a plurality of leads, with the plurality of leads being electrically connected to the plurality of electrodes. The plurality of leads and electrodes may be formed by the deposition of conductive inks or paints, or by the electrodeposition of copper or other conductive metals or materials.

10. 发明申请

US20180333570A1 AUTOMATIC LEAD IDENTIFICATION USING ELECTRIC FIELD FINGERPRINTING 审中-公开
公开(公告)号：US20180333570A1
公开(公告)日：2018-11-22
申请号：US16050546
申请日：2018-07-31
申请人： Boston Scientific Neuromodulation Corporation
发明人： David K.L. Peterson
IPC分类号： A61N1/02 , A61N1/36 , A61N1/05 , A61N1/372
CPC分类号： A61N1/025 , A61N1/0553 , A61N1/36185 , A61N1/37241 , A61N1/37247
摘要： A method, programmer for a neurostimulator, and neurostimulation kit are provided. The kit comprises a neurostimulator, and a plurality of elongated lead bodies configured for being coupled to the neurostimulator, each having a plurality of proximal contacts and a plurality of distal electrodes respectively electrically coupled to the proximal contacts, wherein an in-line connectivity between the electrodes and proximal contacts carried by the different lead bodies differs from each other. Electrical energy is conveyed between the electrodes of the selected lead body and the tissue, an electrical fingerprint is measured at the proximal contacts of the selected lead body in response to the conveyed electrical energy, and the selected lead body is identified based on the measured electrical fingerprint. These steps can be performed by the programmer.

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