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1. 发明授权

US09367915B2 Method and system for analyzing optical coherence tomography (OCT) results using color reflectivity discretization analysis 有权
标题翻译：使用颜色反射率离散化分析分析光学相干断层扫描（OCT）结果的方法和系统
公开(公告)号：US09367915B2
公开(公告)日：2016-06-14
申请号：US14338059
申请日：2014-07-22
申请人： DIOPSYS, INC.
发明人： Peter Derr , Alberto Gonzalez , Laurie Cox
IPC分类号： G06K9/00 , G06T7/00 , G06K9/46 , G06K9/62
CPC分类号： G06T7/0012 , A61B3/102 , G06K9/4652 , G06K9/6284 , G06T7/136 , G06T2207/10024 , G06T2207/10101 , G06T2207/30041 , G06T2207/30242
摘要： A method of analyzing an OCT image. An OCT image has many differently colored dots. The system detects the number of differently colored dots, quantifies them and performs statistical analyses to determine a likelihood of disease. The different colored dots correspond to different retina cell types and structures.
摘要翻译：分析OCT图像的方法。 OCT图像具有许多不同颜色的点。系统检测不同颜色点的数量，量化它们并执行统计分析以确定疾病的可能性。不同的色点对应于不同的视网膜细胞类型和结构。

2. 发明授权

US11185276B2 Vision examination system with improved visually evoked potential waveforms 有权
公开(公告)号：US11185276B2
公开(公告)日：2021-11-30
申请号：US15635736
申请日：2017-06-28
申请人： Diopsys, Inc.
发明人： Laurie A. Cox
IPC分类号： A61B5/378 , A61B5/00 , A61B5/398 , A61B3/10
摘要： A method and a system are disclosed for extracting important signal information. The method examines a group of signals obtained from testing of a patient's nervous system and finds a signal area of interest. Once a cluster of signals that all have the area of interest is found—the system concludes that the area of interest is located and validated. Signals that are not within the cluster are rejected and the signals within the cluster are signal-averaged to yield a signal-averaged waveform. The signal averaged waveform represents the results of the test.

3. 发明授权

US09717465B2 Vision examination system with improved visually evoked potential waveforms 有权
公开(公告)号：US09717465B2
公开(公告)日：2017-08-01
申请号：US13947915
申请日：2013-07-22
申请人： DIOPSYS, INC.
发明人： Laurie A. Cox
IPC分类号： A61B5/00 , A61B5/0476 , A61B5/0484 , A61B5/0496
CPC分类号： A61B5/04842 , A61B3/10 , A61B5/0496 , A61B5/6814 , A61B5/6821 , A61B5/7235 , A61B5/7282 , F04C2270/041
摘要： A method and system for extracting important signal information is disclosed. The method examines a group of signals obtained from testing of a patient's nervous system and finds a signal area of interest. Once a cluster of signals that all have the area of interest is found—the system concludes that the area of interest is located and validated. Signals that are not within the cluster are rejected and the signals within the cluster are signal-averaged to yield a signal-averaged waveform. The signal averaged waveform represents the results of the test.

4. 发明授权

US09026189B2 Electrode sensor assembly for electroretinography and pattern electroretinography 有权
标题翻译：用于视网膜电图和模式视网膜电图的电极传感器组件
公开(公告)号：US09026189B2
公开(公告)日：2015-05-05
申请号：US13678725
申请日：2012-11-16
申请人： Alberto Gonzalez Garcia , Donald E. Lepone
发明人： Alberto Gonzalez Garcia , Donald E. Lepone
IPC分类号： A61B5/0496
CPC分类号： A61B5/0496 , A61B2562/0209
摘要： A multilayer electrode sensor assembly for electroretinography and pattern electroretinography formed as a thin strip to fit under a lower eyelid and contain an electrode in line with the pupil of an eye with signals detected carried through an integrally formed thin conductive strip to a terminal to be connected to an electrical conductor for carrying such signals to an analyzer.
摘要翻译：一种用于视网膜电图和图案视网膜电图的多层电极传感器组件，其形成为薄带以配合在下眼睑下方，并且包含与眼睛的瞳孔一致的电极，其中检测到的信号通过整体形成的薄导电条带传送到要连接的端子到用于将这样的信号传送到分析器的电导体。

5. 发明申请

US20140024964A1 Signal Data Extraction Method and Apparatus 有权
标题翻译：信号数据提取方法和装置
公开(公告)号：US20140024964A1
公开(公告)日：2014-01-23
申请号：US13947915
申请日：2013-07-22
申请人： Diopsys, Inc.
发明人： Laurie A. Cox
IPC分类号： A61B5/00
CPC分类号： A61B5/04842 , A61B3/10 , A61B5/0496 , A61B5/6814 , A61B5/6821 , A61B5/7235 , A61B5/7282 , F04C2270/041
摘要： A method and system for extracting important signal information is disclosed. The method examines a group of signals obtained from testing of a patient's nervous system and finds a signal area of interest. Once a cluster of signals that all have the area of interest is found—the system concludes that the area of interest is located and validated. Signals that are not within the cluster are rejected and the signals within the cluster are signal-averaged to yield a signal-averaged waveform. The signal averaged waveform represents the results of the test.
摘要翻译：公开了一种用于提取重要信号信息的方法和系统。该方法检查从测试患者神经系统获得的一组信号，并找到感兴趣的信号区域。一旦找到了所有感兴趣区域的一组信号，系统就会得出结论，感兴趣的区域是位于和验证的。不在群集内的信号被拒绝，并且群集内的信号被信号平均以产生信号平均波形。信号平均波形表示测试结果。

6. 发明授权

US08787645B2 Method and system for analyzing optical coherence tomography (OCT) results using color reflectivity discretization analysis 有权
标题翻译：使用颜色反射率离散化分析分析光学相干断层扫描（OCT）结果的方法和系统
公开(公告)号：US08787645B2
公开(公告)日：2014-07-22
申请号：US13188193
申请日：2011-07-21
申请人： Peter Derr , Alberto Gonzalez , Laurie Cox
发明人： Peter Derr , Alberto Gonzalez , Laurie Cox
IPC分类号： G06K9/00 , G06K9/34
CPC分类号： G06T7/0012 , A61B3/102 , G06K9/4652 , G06K9/6284 , G06T7/136 , G06T2207/10024 , G06T2207/10101 , G06T2207/30041 , G06T2207/30242
摘要： A method of analyzing an OCT image. An OCT image has many differently colored dots. The system detects the number of differently colored dots, quantifies them and performs statistical analysis to determine a likelihood of disease. The different colored dots correspond to different retina cell types and structures.
摘要翻译：分析OCT图像的方法。 OCT图像具有许多不同颜色的点。系统检测不同颜色点的数量，量化它们并执行统计分析以确定疾病的可能性。不同的色点对应于不同的视网膜细胞类型和结构。

7. 发明授权

US08100533B2 Apparatus and method for screening for glaucoma using visually evoked potentials 有权
标题翻译：使用视觉诱发电位筛选青光眼的装置和方法
公开(公告)号：US08100533B2
公开(公告)日：2012-01-24
申请号：US12435678
申请日：2009-05-05
申请人： Peter H. Derr , Matt Emmer
发明人： Peter H. Derr , Matt Emmer
IPC分类号： A61B3/02 , A61B3/00
CPC分类号： A61B13/00
摘要： A pattern VEP system for screening for glaucoma and other optic nerve related diseases/deficiencies. The system combines high contrast and low contrast testing. The low contrast testing allows for highly sensitive glaucoma testing and the high contrast allows for a sensitive test of the central vision. The system also includes a narrowly tailored method of rejecting corrupted data allowing the system to selectively salvage useful portions of a signal. The system also provides a method of data modeling to locate the N75-P100-N135 complex in a waveform and determine if it falls within the normal range.
摘要翻译：用于筛查青光眼和其他视神经相关疾病/缺陷的模式VEP系统。该系统结合了高对比度和低对比度测试。低对比度测试允许高度敏感的青光眼测试，高对比度允许敏感的中央视力测试。该系统还包括一种狭义地定制的拒绝损坏数据的方法，允许系统选择性地挽救信号的有用部分。该系统还提供了一种数据建模方法，以便在波形中定位N75-P100-N135复合体，并确定其是否在正常范围内。

8. 发明授权

US08083354B2 Simultaneously multi-temporal visual test and method and apparatus therefor 有权
标题翻译：同时进行多时间视觉检测及其方法和装置
公开(公告)号：US08083354B2
公开(公告)日：2011-12-27
申请号：US11905698
申请日：2007-10-03
申请人： Peter H. Derr
发明人： Peter H. Derr
IPC分类号： A61B3/02 , A61B3/00
CPC分类号： A61B3/10 , A61B3/0091 , A61B3/022 , A61B3/032 , A61B5/04842 , A61B5/0496 , A61B5/7257
摘要： A method for determining a likelihood of a visual deficit in a subject uses a simultaneously multi-temporal visual test. At least two visual patterns are simultaneously displayed to the subject. Each pattern reverses in contrast or color at a different display frequency, and each pattern is displayed to a different region of the subject's visual field. Electrical activity of the brain of the subject is captured and sampled, and one or more frequency components are resolved from the resulting signal, where each frequency component corresponds to a different display frequency. The method then involves determining from the frequency components, optionally by comparison between the eyes, a measurement of a likelihood that a visual deficit exists in a particular area.
摘要翻译：用于确定受试者视力缺陷可能性的方法使用同时多时间视觉检查。同时向对象显示至少两个视觉图案。每个图案在不同的显示频率下以对比度或颜色反转，并且每个图案被显示到被摄体的视野的不同区域。拍摄和采样对象的大脑的电活动，并从所得到的信号中解析一个或多个频率分量，其中每个频率分量对应于不同的显示频率。该方法然后包括通过眼睛之间的比较可以从频率分量中确定视觉缺陷存在于特定区域中的可能性的测量。

9. 发明授权

US07578795B2 System and method for vision examination utilizing fault detection 有权
标题翻译：利用故障检测的视觉检查系统和方法
公开(公告)号：US07578795B2
公开(公告)日：2009-08-25
申请号：US09924265
申请日：2001-08-07
申请人： George Z. Hu , Vance Marc Zemon , Peter Derr
发明人： George Z. Hu , Vance Marc Zemon , Peter Derr
IPC分类号： A61B13/00 , A61B5/04
CPC分类号： A61B5/04842 , A61B3/10 , A61B5/7257
摘要： A system and method for performing a vision examination includes displaying a series of visual stimuli for observation by a patient and detecting the patient's visual evoked potentials in response to the visual stimuli. Electrical signals representative of the visual evoked potentials for each stimulus of each series of visual stimuli displayed is amplified, converted to digitized data, recorded and measured. The measured visual evoked potential data is then evaluated and compared to certain predetermined values in order to detect whether or not the measured data is reliable. Data outside of predetermined ranges of values is considered faulty data. For example, the measured data is compared to a maximum value of the output of an amplifier used to enhance the electrical signals, to a predetermined value of the Fourier component at 60 Hz; and to certain ranges to determine if the measured data are outside of expected limits. The occurrence of such data outside these ranges is faulty data. Upon detecting faulty data, new data can be generated until fault free data is obtained or the examination is terminated.
摘要翻译：用于执行视力检查的系统和方法包括显示一系列视觉刺激以供患者观察，并响应于视觉刺激检测患者的视觉诱发电位。表示每个显示的每一系列视觉刺激的每个刺激的视觉诱发电位的电信号被放大，转换为数字化数据，记录和测量。然后评估所测量的视觉诱发电位数据并将其与某些预定值进行比较，以便检测测量数据是否可靠。超出预定范围值的数据被认为是有缺陷的数据。例如，将测量数据与用于增强电信号的放大器的输出的最大值相比较，以60Hz的傅立叶分量的预定值; 并确定某些范围，以确定测量数据是否超出预期的限制。在这些范围之外的这种数据的发生是错误的数据。在检测到故障数据时，可以产生新的数据，直到获得无故障数据或检查结束为止。

10. 发明申请

US20060282008A1 System and method for vision examination utilizing fault detection 审中-公开
公开(公告)号：US20060282008A1
公开(公告)日：2006-12-14
申请号：US11506931
申请日：2006-08-21
申请人： George Hu , Vance Zemon , Peter Derr
发明人： George Hu , Vance Zemon , Peter Derr
IPC分类号： A61B13/00 , A61B5/04
CPC分类号： A61B5/04842 , A61B3/10 , A61B5/7257
摘要： A system and method for performing a vision examination includes displaying a series of visual stimuli for observation by a patient and detecting the patient's visual evoked potentials in response to the visual stimuli. Electrical signals representative of the visual evoked potentials for each stimulus of each series of visual stimuli displayed is amplified, converted to digitized data, recorded and measured. The measured visual evoked potential data is then evaluated and compared to certain predetermined values in order to detect whether or not the measured data is reliable. Data outside of predetermined ranges of values is considered faulty data. For example, the measured data is compared to a maximum value of the output of an amplifier used to enhance the electrical signals, to a predetermined value of the Fourier component at 60 Hz; and to certain ranges to determine if the measured data are outside of expected limits. The occurrence of such data outside these ranges is faulty data. Upon detecting faulty data, new data can be generated until fault free data is obtained or the examination is terminated.

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