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1. 发明申请

US20090318548A1 PARA-QUINOL DERIVATIVES AND METHODS OF STEREO SELECTIVELY SYNTHESIZING AND USING SAME 审中-公开
标题翻译： PARA-QUINOL衍生物和方法选择性合成和使用方法
公开(公告)号：US20090318548A1
公开(公告)日：2009-12-24
申请号：US12438926
申请日：2007-08-23
申请人： Guy L. Plourde , R. Randy Spaetzel
发明人： Guy L. Plourde , R. Randy Spaetzel
IPC分类号： A61K31/343 , C07D307/94 , C07D493/20 , C07D497/10 , A61K31/34
CPC分类号： C07D307/94 , C07D493/10 , C07D493/20 , Y02P20/55
摘要： This application relates to para-quinol derivatives, such as analogues of manumycins, aranorosins and gymnastatins. This application also relates to methods of synthesizing and using the para-quinol derivatives. In one embodiment of the invention a compound having the chemical structure (I) is provided wherein X1 and X2 are carbon atoms either joined by double bond or joined by a single bond and comprising constituents of an epoxide ring or a hydroxyethylene moiety; X3 and X4 are carbon atoms either joined by double bond or joined by a single bond and comprising constituents of an epoxide ring; R1 is selected from the group consisting of branched alkyl chains, unbranched alkyl chains, cycloalkyl groups, aromatic groups, alcohols, ethers, amines, and substituted or unsubstituted ureas, esters, aldehydes and carboxylic acids; and R2 is selected from the group consisting of H, OH and NHR3 wherein R3 is a nitrogen protecting group. In a particular embodiment of the invention R1 is a polyunsaturated carbon chain as found in biologically active manumycins. The applicant's synthetic method may involve diasteroselective formation of a spirolactone in an oxidative spiroannulation process using tyrosine or a tyrosine derivative having a chiral centre as a starting material.
摘要翻译：本申请涉及对 - 喹啉衍生物，例如manumycins，aranorosins和体坛运动员的类似物。本申请还涉及合成和使用对 - 喹啉衍生物的方法。在本发明的一个实施方案中，提供具有化学结构（I）的化合物，其中X1和X2是通过双键连接或通过单键连接并且包含环氧化物环或羟基亚乙基部分的组分的碳原子; X 3和X 4是通过双键连接或通过单键连接并且包含环氧化物环的组分的碳原子; R1选自支链烷基链，无支链烷基链，环烷基，芳族基团，醇类，醚类，胺类和取代或未取代的脲类，酯类，醛类和羧酸类; 并且R 2选自H，OH和NHR 3，其中R 3是氮保护基。在本发明的一个具体实施方案中，R 1是在生物活性的马铃薯霉素中发现的多不饱和碳链。申请人的合成方法可以包括使用酪氨酸或具有手性中心作为起始原料的酪氨酸衍生物在氧化旋转方法中对对映体形成螺内酯。

2. 发明授权

US07829855B2 Methods and apparatus for determining fibre orientation 有权
标题翻译：用于确定纤维取向的方法和装置
公开(公告)号：US07829855B2
公开(公告)日：2010-11-09
申请号：US12161292
申请日：2007-01-17
申请人： Matthew E. Reid , Robert Fedosejevs
发明人： Matthew E. Reid , Robert Fedosejevs
IPC分类号： G01J5/58
CPC分类号： G01N21/23 , G01N21/3563 , G01N21/3581 , G01N33/365 , G01N2021/8444 , G01N2021/8681
摘要： Fiber distribution characteristics such as the bulk average orientation of fibers in composite fibrous materials can be evaluated based on the variation in the speed with which polarized electromagnetic signals propagate through the material as a function of angle. The electromagnetic radiation may comprise terahertz radiation. The composite fibrous materials may be wood-containing materials such as oriented strand board or particle board.
摘要翻译：基于复合纤维材料中纤维的体积平均取向的纤维分布特征可以基于极化电磁信号通过材料传播的速度随角度的变化而被评估。电磁辐射可以包括太赫兹辐射。复合纤维材料可以是含木材料，例如定向刨花板或刨花板。

3. 发明申请

US20050231468A1 Methods and systems for interacting with virtual objects 审中-公开
标题翻译：与虚拟对象交互的方法和系统
公开(公告)号：US20050231468A1
公开(公告)日：2005-10-20
申请号：US11106616
申请日：2005-04-15
申请人： Liang Chen , Charles Brown
发明人： Liang Chen , Charles Brown
IPC分类号： G06F3/00 , G06F3/01 , G06F3/02 , G06F3/033 , G09G5/00
CPC分类号： G06F3/011 , G06F3/016
摘要： The invention provides an apparatus for interacting with a computer system comprising a processor coupled to a display. The apparatus comprises a body configured to be moveable by a user. The body has a position sensor therein for producing a main position signal. A plurality of probe members are connected to the body. A plurality of transducers are coupled to the probe members for producing probe motion signals representative of positions of the probe members. A plurality of actuators are coupled to the probe members to selectively apply force to the probe members. A control system is coupled to the position sensor, the transducers and the actuators for receiving the main position signal and the probe position signals and interacting with the processor in order to produce control signals for controlling each of the probe members.
摘要翻译：本发明提供了一种用于与包括耦合到显示器的处理器的计算机系统交互的装置。该装置包括被配置为可由用户移动的主体。主体具有位置传感器，用于产生主位置信号。多个探针构件连接到主体。多个换能器耦合到探针构件，用于产生代表探针构件的位置的探针运动信号。多个致动器联接到探针构件以选择性地向探针构件施加力。控制系统耦合到位置传感器，换能器和致动器，用于接收主位置信号和探头位置信号并与处理器相互作用，以产生用于控制每个探针构件的控制信号。

4. 发明申请

US20100219343A1 METHODS AND APPARATUS FOR DETERMINING FIBRE ORIENTATION 有权
标题翻译：用于确定光纤定向的方法和装置
公开(公告)号：US20100219343A1
公开(公告)日：2010-09-02
申请号：US12161292
申请日：2007-01-17
申请人： Matthew E. Reid , Robert Fedosejevs
发明人： Matthew E. Reid , Robert Fedosejevs
IPC分类号： G01J5/02 , G01N21/17 , G01N22/00
CPC分类号： G01N21/23 , G01N21/3563 , G01N21/3581 , G01N33/365 , G01N2021/8444 , G01N2021/8681
摘要： Fibre distribution characteristics such as the bulk average orientation of fibres in composite fibrous materials can be evaluated based on the variation in the speed with which polarized electromagnetic signals propagate through the material as a function of angle. The electromagnetic radiation may comprise terahertz radiation. The composite fibrous materials may be wood-containing materials such as oriented strand board or particle board.
摘要翻译：基于复合纤维材料中的纤维的体积平均取向的纤维分布特征可以基于偏振电磁信号通过材料作为角度传播的速度的变化来评估。电磁辐射可以包括太赫兹辐射。复合纤维材料可以是含木材料，例如定向刨花板或刨花板。

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