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1. 发明授权

US11542213B2 Reactive inorganic coatings for agricultural fertilizers 有权
公开(公告)号：US11542213B2
公开(公告)日：2023-01-03
申请号：US17126461
申请日：2020-12-18
申请人： Anuvia Plant Nutrients Corporation
发明人： Sanford A. Siegel , Jeffrey C. Burnham
IPC分类号： C05G5/30 , C05F3/00 , C05F5/00 , C05D9/02 , C05G5/12
摘要： The invention relates to a coated granular fertilizer, preferably wherein granules are sulfate-based or phosphate-based. When sulfate-based granules, as in ammonium sulfate, the coating substance is an inorganic salt of alkaline earth elements, preferably calcium, such that when applied to the surface of fertilizers, forms calcium sulfate, preferably a calcium sulfate-dihydrate, as a protective coating. For a reactive coating of a thiosulfate, free sulfuric acid present on the granule reacts to provide an elemental sulfur coating. For ammonium phosphate-based granules, coatings may comprise compounds of Ca++, Al+++ and/or Fe+++ salts thereby forming a calcium, an aluminum, an iron, or mixed cation phosphate protective coating. Thiosulfate is also effective with phosphate-based granules which are manufactured with sulfuric acid. Granules coated according to the disclosure have advantageous properties as the coating can be applied in a specified and sparing manner due to its tendency to adhere to surfaces during the reaction. Coated fertilizer granules of the disclosure are also advantageous in that, with regard to the applied amount of coating, they provide increased resistance to dusting in long term warehouse storage, to moisture uptake and to oxidative heating. Coating components also add nutrients to plants that can provide nutrients over a longer period of time such as a slow-release characteristic.

2. 发明授权

US11299703B2 Portable disposable re-usable culture device for rapid diagnosis of infectious agents 有权
公开(公告)号：US11299703B2
公开(公告)日：2022-04-12
申请号：US15131338
申请日：2016-04-18
申请人： Vax-Immune, LLC
发明人： Bhairavi Parikh
IPC分类号： C12M1/34 , C12M1/36 , C12M1/00 , C12M1/26 , C12M3/06 , C12Q1/04 , C12M1/30
摘要： The present invention is directed to compositions, tools, methods and devices to culture microorganisms and, in particular, to compositions, tools, methods and devices for the detection of microorganisms in biological samples.

3. 发明授权

US11299702B2 Portable disposable re-usable culture device for rapid diagnosis of infectious agents 有权
公开(公告)号：US11299702B2
公开(公告)日：2022-04-12
申请号：US16004590
申请日：2018-06-11
申请人： Vax-Immune, LLC
发明人： Bhairavi Parikh , James Stone
IPC分类号： C12M1/34 , C12M1/00 , C12M3/00 , C12M1/02 , C12M1/30
摘要： The present invention is directed to compositions, tools, methods and devices to culture microorganisms and, in particular, to compositions, tools, methods and devices for the detection of microorganisms in biological samples.

4. 发明授权

US11272814B2 Toilet/shower combination fixture 有权
公开(公告)号：US11272814B2
公开(公告)日：2022-03-15
申请号：US17101112
申请日：2020-11-23
申请人： Wilco Partnership, LLC
发明人： Gregg Williams
IPC分类号： A47K4/00 , A47K3/28 , A47K3/34 , A47K3/32
摘要： A combination shower and toilet is disclosed. The device comprises a base, a toilet bowl extending from the base, a shower head coupled to the base, a pivoting curtain rod coupled to the base, and a shower curtain coupled to the curtain rod.

5. 发明授权

US11260422B2 System of applying a coating to a vehicle 有权
公开(公告)号：US11260422B2
公开(公告)日：2022-03-01
申请号：US16006293
申请日：2018-06-12
申请人： Ground Effects, Ltd.
发明人： Benjamin William Dollar , Michael Scott Boyko , Robert William Scott , Bradley John Pattison
IPC分类号： B05D7/14 , B05D1/06 , B32B15/04 , B05B12/20 , B25J11/00 , B05B12/00 , B05B13/00 , B25J9/00
摘要： A system of applying a coating to a vehicle in sequence with vehicle manufacture is disclosed. The vehicle may be inspected and/or logged into inventory. The vehicle may be electronically recorded into inventory using a computerized data acquisition and/or process control system. The vehicle may be prepared by an operator. The vehicle preparation may include applying masking materials to at least a portion of the vehicle. The vehicle preparation may include application of a pre-treatment to at least a portion of the vehicle. A coating may be applied to at least a portion of the vehicle. The coating may include one or more layers. The masking materials may be removed from the vehicle after the completion of the coating application. The vehicle may be electronically recorded into inventory using a data acquisition and/or process control system. The vehicle may be delivered and/or returned to the vehicle manufacturer.

6. 发明授权

US11171694B2 Integrated circuit for scalable beamforming and frequency channelization 有权
公开(公告)号：US11171694B2
公开(公告)日：2021-11-09
申请号：US16926911
申请日：2020-07-13
申请人： Associated Universities, Inc.
发明人： Omar Artemi Yeste Ojeda , Stephen Daniel Wunduke
IPC分类号： H04B1/38 , H04B7/0426 , H04B7/005 , H04B7/01 , H04B7/06
摘要： A general-purpose integrated circuit capable of scaling to meet the requirements of a beamforming system for a wide range of applications and benefit from economies of scale is disclosed. The integrated circuit includes a delay and phase correcting engine in order to reference the incoming data to a common array center and steering direction. It also includes a frequency channelization engine to perform phase-shift beamforming tasks effectively and/or frequency channelize the output data stream. A flexible reconfigurable routing logic can be included, which allows a multiplicity of operation modes, and generates a multiplicity of linear combinations of the input and internally generated data streams.

7. 发明授权

US10758606B2 VLP stabilized vaccine compositions 有权
公开(公告)号：US10758606B2
公开(公告)日：2020-09-01
申请号：US15257143
申请日：2016-09-06
申请人： Inventprise, LLC
发明人： Subhash V. Kapre
IPC分类号： A61K39/29 , A61K39/295 , A61K47/42 , C07K14/025 , A61K39/12 , A61K9/00 , A61K9/19 , A61K47/10 , C07K14/005 , C12N7/00 , A61K39/00
摘要： The invention is directed to compositions and methods for the stabilization of viral and bacterial vaccines. Vaccines of the invention are contained in VLPs with stabilizing agents such as, for example, sugar alcohols (e.g., sorbitol) and degraded gelatins. Preferably the gelatin has an average molecular weight of 10,000 kilodaltons or less. These vaccines have a substantially improved thermostability as well as long term stability. The invention is also directed to the manufacture of a vaccine or the invention and methods for the administration of a vaccine of the invention to patients.

8. 发明授权

US10604936B2 Gutter guard for floating gutter and kit 有权
公开(公告)号：US10604936B2
公开(公告)日：2020-03-31
申请号：US16182841
申请日：2018-11-07
申请人： Stéphane Brochu
发明人： Stéphane Brochu
IPC分类号： E04D13/076 , E04D13/072 , E04D13/068
摘要： A gutter guard for retaining a gutter and for covering an opening of the gutter provided. The gutter has a front wall and a rear wall and the opening is defined by a top edge of the front wall and the top edge of the rear wall. The gutter guard includes a front portion for operatively engaging the front wall of the gutter, a rear portion having an upwardly and rearwardly extending hook member for retaining the rear wall of the gutter and an upstanding member fastenable to an upstanding support structure, and a central portion extending between the front portion and the rear portion and having a plurality of throughholes formed therein. The gutter guard may be multi-layered, having a first sheet member and a second sheet member that are spaced apart and having non-aligned throughholes. A gutter guard kit can include at least one gutter guard and a gutter that are operatively engageable with one another.

9. 发明授权

US10597664B2 Expression and purification of CRM proteins and related proteins, and protein domains 有权
公开(公告)号：US10597664B2
公开(公告)日：2020-03-24
申请号：US16154020
申请日：2018-10-08
申请人： Fina BioSolutions, LLC
发明人： Natalia Oganesyan , Andrew Lees
IPC分类号： A61K39/00 , A61K39/385 , A61K39/02 , A61K39/40 , A61K48/00 , A01N63/00 , C12N15/70 , C07K14/34 , C07K1/22 , C07K14/33 , C07K14/235 , A61K47/60 , C12N9/02 , C12N9/06 , A61K38/00
摘要： The present invention is directed to the cells, compositions and methods for the production of recombinant protein. In particular, the invention is directed to a production process for obtaining high levels of soluble recombinant CRM197 protein from E. coli. Cells preferably contain one or more mutations of disulfide reductase genes, so that disulfide reductase activity is reduced. The invention also relates to purification method for CRM197 as well as characterization of properly folded CRM197 protein.

10. 发明授权

US10576147B2 Muramyl peptide derivative compound, synthesis and uses thereof 有权
公开(公告)号：US10576147B2
公开(公告)日：2020-03-03
申请号：US16062503
申请日：2016-12-10
申请人： BHARAT BIOTECH INTERNATIONAL LIMITED , COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
发明人： Krishna Murthy Ella , Ganneru Brunda , Halmathur Mahabalarao Sampath Kumar , Miryala Sreekanth
IPC分类号： A61K38/00 , A61K39/39 , A61K39/00
摘要： The invention relates to novel Muramyl Dipeptide (MDP) derivative compound of structural Formula-VIII, a process for synthesis, intermediates used in the synthesis and use thereof; wherein R1 and R2 both are hydrogen; or R1 is hydrogen and R2 is alkyl or aryl; or R1 is alkyl or aryl and R2 is hydrogen; or R1 and R2 both are alkyl or aryl (same or different groups); wherein alkyl group constitute C1-C6 alkyl or higher (both linear and branched) with or without heteroatoms; and aryl group constitute phenyl, substituted phenyl, heteraryl, arylalkyl and polynuclear aromatics. These compounds possess excellent pharmacological properties, in particular immunomodulating properties for use as adjuvant in vaccine formulations. These compounds are, particularly useful as adjuvants in vaccines.

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