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2. 发明申请

US20130295111A1 METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH HYPERACTIVE IMMUNE SYSTEM 审中-公开
标题翻译：用于治疗与高血压免疫系统相关的疾病的方法和组合物
公开(公告)号：US20130295111A1
公开(公告)日：2013-11-07
申请号：US13816121
申请日：2011-08-09
申请人： Rosa Ana Gonzalez-Quintial , Roberto G. Baccala , Brian R. Lawson , Argyrios N. Theofilopoulos
发明人： Rosa Ana Gonzalez-Quintial , Roberto G. Baccala , Brian R. Lawson , Argyrios N. Theofilopoulos
IPC分类号： A61K39/395 , A61K31/713
CPC分类号： A61K39/3955 , A61K31/00 , A61K31/713 , A61K2039/505 , C07K16/2866
摘要： The present invention provides methods and compositions for treating disorders associated with hyperactive immune responses. The invention also provides methods for lithibiting activation of CD4+ T cells and/or suppressing proliferation other overactivated T cells (e.g., CD4CD8 T cells). These methods typically involve the administration to the subject a therapeutically effective amount of a compound that lithibits or suppresses IL-7 signaling or IL- 15 signaling.
摘要翻译：本发明提供了用于治疗与多动症免疫应答相关的疾病的方法和组合物。本发明还提供了用于刺激CD4 + T细胞的活化和/或抑制其它过度活化的T细胞（例如CD4CD8T细胞）的增殖的方法。这些方法通常涉及向受治疗者施用治疗有效量的化学物质，其可以利用或抑制IL-7信号传导或IL-15信号传导。

3. 发明申请

US20130238404A1 COMPETENCE ASSESSMENT METHOD AND SYSTEM 审中-公开
标题翻译：能力评估方法与系统
公开(公告)号：US20130238404A1
公开(公告)日：2013-09-12
申请号：US13739918
申请日：2013-01-11
申请人： Fernando Alba ELIAS , Ana Gonzalez MARCOS , Joaquin Ordieres MERE
发明人： Fernando Alba ELIAS , Ana Gonzalez MARCOS , Joaquin Ordieres MERE
IPC分类号： G06Q10/06
CPC分类号： G06Q10/06398
摘要： The present invention relates to a method and competence assessment system for assessing the competences of a participant in a project. The method includes assessing at least one competence of at least one participant in a project by applying a mathematical formula. The project includes at least one phase, at least one competence of an assessed participant intervening in at least one phase of the project, the competence being assessed by at least one assessor figure by at least one piece of evidence.
摘要翻译：本发明涉及一种用于评估项目参与者的能力的方法和能力评估系统。该方法包括通过应用数学公式评估项目中的至少一个参与者的至少一个能力。该项目包括至少一个阶段，至少有一个参与者至少参加一个项目的至少一个阶段的能力，由至少一个评估员至少一个证据评估的能力。

4. 发明授权

US08459533B2 Carton with handle 有权
标题翻译：纸箱与手柄
公开(公告)号：US08459533B2
公开(公告)日：2013-06-11
申请号：US12711550
申请日：2010-02-24
申请人： Emili Requena , Ana Gonzalez
发明人： Emili Requena , Ana Gonzalez
IPC分类号： B65D5/46
CPC分类号： B65D71/36 , B65D2571/00141 , B65D2571/00456 , B65D2571/00462 , B65D2571/00524 , B65D2571/0066 , B65D2571/00728
摘要： A carton for containing a plurality of articles. The carton comprises a first top panel, a second top panel, a bottom panel, a first side panel, and a second side panel. A handle comprises a first handle panel and a second handle panel. The first handle panel comprises a central portion in the top panel and an end portion in a first top end flap. The second handle panel comprises a first portion in the second top panel and a second portion in a second top end flap. The central portion of the first handle panel is attached to the first portion of the second handle panel and the end portion of the first handle panel is attached to the second portion of the second handle panel.
摘要翻译：用于容纳多个物品的纸箱。纸箱包括第一顶板，第二顶板，底板，第一侧板和第二侧板。手柄包括第一手柄板和第二手柄板。第一手柄板包括顶板中的中心部分和第一顶端折板中的端部。第二手柄板包括第二顶板中的第一部分和第二顶端折板中的第二部分。第一把手面板的中心部分附接到第二把手面板的第一部分，并且第一把手面板的端部附接到第二把手面板的第二部分。

5. 发明授权

US08356744B2 Carton with reinforcing insert 有权
标题翻译：装有加强插件的纸箱
公开(公告)号：US08356744B2
公开(公告)日：2013-01-22
申请号：US12687454
申请日：2010-01-14
申请人： Kirsten L. Brand , Ana Gonzalez
发明人： Kirsten L. Brand , Ana Gonzalez
IPC分类号： B65D5/42 , B31B17/00
CPC分类号： B65D71/36 , B65D2571/00141 , B65D2571/00469 , B65D2571/0053 , B65D2571/00549 , B65D2571/00574 , B65D2571/0066 , B65D2571/00728
摘要： A carton for containing a plurality of articles. The carton comprises panels that extend at least partially around an interior of the carton. The panels comprise a top panel, a first side panel, a second side panel, and a bottom panel. The carton includes a reinforcing insert comprising at least a first insert panel foldably connected to a second insert panel. The first insert panel is at least partially in face-to-face contact with at least the top panel and the second insert panel is at least partially in face-to-face contact with the first insert panel.
摘要翻译：用于容纳多个物品的纸箱。纸箱包括至少部分地围绕纸箱内部延伸的面板。面板包括顶板，第一侧板，第二侧板和底板。纸箱包括加强插入件，其包括可折叠地连接到第二插入面板的至少第一插入面板。第一插入面板至少部分地与至少顶板面对面地接触，并且第二插入面板至少部分地与第一插入面板面对面接触。

6. 发明申请

US20110284623A1 PACKAGE FOR CONTAINERS 有权
标题翻译：集装箱包装
公开(公告)号：US20110284623A1
公开(公告)日：2011-11-24
申请号：US13111029
申请日：2011-05-19
申请人： Edward W. Jones , Ana Gonzalez , Emili Requena , Jean-Manuel Gomes , Kevin T. May , Colin Ford , Matthew Sundquist
发明人： Edward W. Jones , Ana Gonzalez , Emili Requena , Jean-Manuel Gomes , Kevin T. May , Colin Ford , Matthew Sundquist
IPC分类号： B65D71/12 , B65B11/00 , B65D5/54 , B65D75/00 , B65D5/42
CPC分类号： B65D71/46 , B65B11/004 , B65B21/242 , B65B43/10 , B65D2571/00209 , B65D2571/0029 , B65D2571/00339 , B65D2571/00561 , B65D2571/00574 , B65D2571/0066 , B65D2571/00716 , B65D2571/00759 , B65D2571/00771
摘要： A carrier that is at least partially holding a plurality of containers. The carrier can include a plurality of panels comprising a bottom panel, a first side panel foldably connected to the bottom panel, a second side panel foldably connected to the bottom panel, a first top panel foldably connected to the first side panel, and a second top panel foldably connected to the second side panel. At least one container-receiving feature extends in at least the bottom panel. The at least one container-receiving feature can at least partially receive at least one container of the plurality of containers. At least one retention flap is foldably connected to the first top panel or the second top panel. The at least one retention flap engages at least a portion of a flange of at least one container.
摘要翻译：至少部分地保持多个容器的载体。载体可以包括多个面板，其包括底板，可折叠地连接到底板的第一侧板，可折叠地连接到底板的第二侧板，可折叠地连接到第一侧板的第一顶板，以及第二侧板顶板可折叠地连接到第二侧板。至少一个容器接收特征至少在底板中延伸。至少一个容器接收特征可以至少部分地容纳多个容器中的至少一个容器。至少一个保持翼片可折叠地连接到第一顶板或第二顶板。所述至少一个保持翼接合至少一个容器的凸缘的至少一部分。

7. 发明申请

US20080108091A1 Proteomic Patterns of Cancer Prognostic and Predictive Signatures 审中-公开
标题翻译：癌症预后和预测特征的蛋白质组学模式
公开(公告)号：US20080108091A1
公开(公告)日：2008-05-08
申请号：US11835234
申请日：2007-08-07
申请人： Bryan Hennessy , Gordon Mills , Kevin Coombes , Ana Gonzalez-Anguelo , Mark Carey
发明人： Bryan Hennessy , Gordon Mills , Kevin Coombes , Ana Gonzalez-Anguelo , Mark Carey
IPC分类号： G01N33/574 , C12N5/06
CPC分类号： G01N33/574 , G01N2800/52
摘要： The invention provides method for predicting whether a cancer patient will respond to a therapy. Methods of the invention may involve examining protein from a cell of the cancer patient by determining the binding of a panel of antibodies to the protein. Methods of the invention may be used to generate both expression and activation profiles for cells from a cancer patient. Profiles from a cancer patient may then be compared to known profiles for therapy responders and non-responders to predict the individual response of the patient. For example, methods of the invention may be used to determine whether an ovarian or breast cancer patient will respond to a therapeutic protocol.
摘要翻译：本发明提供了用于预测癌症患者是否将对治疗作出反应的方法。本发明的方法可以包括通过确定一组抗体与蛋白质的结合来检查来自癌症患者的细胞的蛋白质。本发明的方法可用于产生来自癌症患者的细胞的表达和活化谱。然后可以将来自癌症患者的分布与用于治疗应答者和非应答者的已知概况进行比较以预测患者的个体反应。例如，本发明的方法可用于确定卵巢癌或乳腺癌患者是否将对治疗方案作出反应。

8. 发明授权

US08740051B2 Carton with handle 有权
标题翻译：纸箱与手柄
公开(公告)号：US08740051B2
公开(公告)日：2014-06-03
申请号：US13182668
申请日：2011-07-14
申请人： Ana Gonzalez
发明人： Ana Gonzalez
IPC分类号： B65D5/462
CPC分类号： B65D71/36 , B65D2571/00456 , B65D2571/00462 , B65D2571/00574 , B65D2571/00654 , B65D2571/0066 , B65D2571/00728
摘要： A carton for containing a plurality of articles. The carton can comprise a plurality of panels that extends at least partially around an interior of the carton. The plurality of panels can comprise an inner top panel and an outer top panel that at least partially overlaps the inner top panel. An outer end flap can be foldably connected to the outer top panel at an upper corner of the carton, and the outer end flap can at least partially close an end of the carton. A handle can comprise a handle panel defined in at least the inner top panel and a handle flap defined in the outer end flap. The handle panel can be mounted to the handle flap so that a portion of the handle panel is covered by the upper corner.
摘要翻译：用于容纳多个物品的纸箱。纸箱可以包括至少部分地围绕纸箱内部延伸的多个面板。多个面板可以包括至少部分地与内顶板重叠的内顶板和外顶板。外端片可以在纸箱的上角部处可折叠地连接到外顶板，并且外端翼片可以至少部分地封闭纸箱的端部。手柄可以包括限定在至少内顶板中的手柄板和限定在外端挡板中的手柄挡板。把手面板可以安装在手柄上，使手柄面板的一部分被上角覆盖。

9. 发明授权

US08439253B2 Carton 有权
标题翻译：纸箱
公开(公告)号：US08439253B2
公开(公告)日：2013-05-14
申请号：US12770098
申请日：2010-04-29
申请人： Emili Requena , Ana Gonzalez
发明人： Emili Requena , Ana Gonzalez
IPC分类号： B65D5/46
CPC分类号： B65D71/36 , B65D5/0025 , B65D5/28 , B65D5/6664 , B65D81/263 , B65D85/34 , B65D2571/00141 , B65D2571/00469 , B65D2571/00543 , B65D2571/0066 , B65D2571/00753 , B65D2571/00845 , B65D2571/00864
摘要： A blank, carton, or package including a handle formed in a top panel is described. Deformation lines can be included on the blank or carton to allow the handle to flex, thereby increasing handle strength. The blank can include corner-forming panels attached to end flaps that can be used to form corners in the formed carton or package. The corners provide reinforcement strength to allow stacking of the cartons or packages, such as on pallets or during shipment. Openings can be provided in select areas of the blank, carton, or package to allow ventilation to and from the interior of the carton or package. Connecting panels in the top panel can be removed to dispense articles from the carton or package.
摘要翻译：描述了包括形成在顶板中的手柄的坯料，纸箱或包装。变形线可以包括在坯料或纸箱上，以允许手柄弯曲，从而增加手柄强度。坯件可以包括附接到端板的角形板，其可用于在所形成的纸箱或包装中形成角部。角部提供加固强度，以允许堆叠纸箱或包装，例如在托盘上或在运输期间。可以在空白，纸箱或包装的选定区域提供开口，以允许通往纸箱或包装内部的通风。顶部面板中的连接面板可以拆下，从纸箱或包装中分配物品。

10. 发明授权

US08387784B2 Package for containers 失效
标题翻译：容器包装
公开(公告)号：US08387784B2
公开(公告)日：2013-03-05
申请号：US12834216
申请日：2010-07-12
申请人： Ana Gonzalez , Emili Requena , Paul Bradford , Andrea Coltri-DePaula
发明人： Ana Gonzalez , Emili Requena , Paul Bradford , Andrea Coltri-DePaula
IPC分类号： B65D75/00
CPC分类号： B65D71/42 , B65D2571/0029 , B65D2571/00314 , B65D2571/0066
摘要： A package for holding a plurality of containers. The package has a top panel, end panels and side panels. The package has retention features in the top panel for retaining the containers. The package has handle features in the end panel for forming a handle for grasping and carrying the package.
摘要翻译：用于容纳多个容器的包装。该封装具有顶板，端板和侧板。该包装在顶部面板中具有保留容器的保留特征。该封装在端板中具有用于形成用于抓握和携带包装的手柄的把手特征。

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