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1. 发明申请

US20220257318A1 HIGH VOLTAGE ABLATION CATHETER SYSTEM 有权
公开(公告)号：US20220257318A1
公开(公告)日：2022-08-18
申请号：US17739094
申请日：2022-05-07
申请人： Hugo Andres Belalcazar
发明人： Hugo Andres Belalcazar
IPC分类号： A61B18/14 , A61B18/12
摘要： A system for ablating bodily tissue of a patient includes a high-voltage electrical generator configured to provide electrical pulses of at least 500 volts, a fluid having an electrical conductivity of not more than 0.01 Siemens per meter, and an ablation catheter that includes a catheter shaft, an expandable membrane attached to the catheter shaft, and a plurality of electrodes, each electrically coupled to the high-voltage electrical generator. The fluid inflates the expandable membrane when provided to the interior space of the expandable membrane.

2. 发明申请

US20130072831A1 METHOD AND APPARATUS FOR IMPROVED CARDIO-PULMONARY RESUSCITATION USING CYCLES WITH 4 AND 5 STATES 审中-公开
标题翻译：使用4和5状态循环改善心脏电图恢复的方法和装置
公开(公告)号：US20130072831A1
公开(公告)日：2013-03-21
申请号：US13674029
申请日：2012-11-10
申请人： Hugo Andres Belalcazar
发明人： Hugo Andres Belalcazar
IPC分类号： A61H31/00
CPC分类号： A61H31/00 , A61H31/006 , A61H31/007 , A61H2201/123 , A61H2201/5007 , A61H2201/5061 , A61H2201/5097 , A61M16/06 , A61M16/0677 , A61M16/10 , A61M16/202 , A61M16/203 , A61M16/208 , A61M2202/0208 , A61M2205/332
摘要： A cardio pulmonary CPR device and method provides enhanced circulation by an inventive sequence of states of chest compression and airway valve opening and closure. The embodiments of the invention produce enhanced circulation during cardiac arrest, while maintaining a degree of ventilation to the patient, including oxygen delivery in some embodiments. Some embodiments include mechanical compression units. Other embodiments include a compression sensor to detect manually delivered compressions.
摘要翻译：心肺CPR装置和方法通过胸部压缩和气道开阀和关闭的创造性状态提供增强的循环。在一些实施方案中，本发明的实施方案在心脏骤停期间产生增强的循环，同时在患者体内保持一定程度的通气，包括氧气输送。一些实施例包括机械压缩单元。其他实施例包括用于检测手动递送的压缩的压缩传感器。

3. 发明授权

US07640056B2 Monitoring fluid in a subject using an electrode configuration providing negative sensitivity regions 有权
标题翻译：使用提供负敏感区域的电极配置来监测受试者中的流体
公开(公告)号：US07640056B2
公开(公告)日：2009-12-29
申请号：US11419123
申请日：2006-05-18
申请人： Andres Belalcazar
发明人： Andres Belalcazar
IPC分类号： A61B5/05
CPC分类号： A61B5/0537 , A61B5/4869
摘要： An amount of fluid in a thoracic or other region of a subject may be monitored by internally injecting an electrical energy stimulus (e.g., constant voltage source) through the region, detecting voltage resulting from the electrical energy stimulus, and calculating a fluid volume indicative signal. The injected energy stimulus creates a first lead field. The responsive voltage is detected using an electrode configuration that defines a second lead field, which is arranged in a negative sensitivity configuration with respect to the first lead field at the region being monitored.
摘要翻译：可以通过在该区域内部注入电能刺激（例如，恒定电压源）来检测受试者的胸部或其他区域中的流体的量，检测由电能刺激产生的电压，以及计算流体体积指示信号。注入能量刺激产生了第一个引线场。使用限定第二引线场的电极配置来检测响应电压，该引线场在被监视的区域处相对于第一引线场布置成负的灵敏度配置。

4. 发明申请

US20080097539A1 METHOD AND APPARATUS FOR DETECTING FIBRILLATION USING CARDIAC LOCAL IMPEDANCE 有权
标题翻译：使用心脏局部阻力检测纤维化的方法和装置
公开(公告)号：US20080097539A1
公开(公告)日：2008-04-24
申请号：US11550923
申请日：2006-10-19
申请人： Andres Belalcazar
发明人： Andres Belalcazar
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61N1/3956
摘要： A cardiac rhythm management (CRM) system detects tachyarrhythmia using cardiac local impedance indicative of cardiac local wall motion. A cardiac local impedance signal indicative of an impedance of a cardiac region is sensed by using a pair of bipolar electrodes placed in that cardiac region. Tachyarrhythmia such as VF is detected by analyzing one or more cardiac local impedance signals sensed in one or more cardiac regions.
摘要翻译：心律管理（CRM）系统使用指示心脏局部壁运动的心脏局部阻抗来检测快速性心律失常。通过使用放置在该心脏区域中的一对双极电极来感测指示心脏区域的阻抗的心脏局部阻抗信号。通过分析在一个或多个心脏区域中感测到的一个或多个心脏局部阻抗信号来检测诸如VF的快速性心律失常。

5. 发明申请

US20080064980A1 Implantable Medical Device and Methods for Automated Detection of Infection 有权
标题翻译：植入式医疗器械和自动检测感染的方法
公开(公告)号：US20080064980A1
公开(公告)日：2008-03-13
申请号：US11833548
申请日：2007-08-03
申请人： Kent Lee , Jonathan T. Kwok , Hugo Andres Belalcazar , Jennifer Lynn Pavlovic , Ronald W. Heil
发明人： Kent Lee , Jonathan T. Kwok , Hugo Andres Belalcazar , Jennifer Lynn Pavlovic , Ronald W. Heil
IPC分类号： A61B5/053 , A61M31/00 , A61N1/05
CPC分类号： A61B5/053 , A61B5/02405 , A61B5/036 , A61B5/0816 , A61B5/145 , A61B5/14539 , A61B5/412 , A61N1/36521
摘要： The invention relates to systems, devices, and methods for detecting infections associated with implantable medical devices. In an embodiment, the invention includes a method of detecting infection in a patient including measuring a physiological parameter using a chronically implanted sensor at a plurality of time points and evaluating the physiological parameter measurements to determine if infection is indicated. In an embodiment, the invention includes an implantable medical device including a first chronically implantable sensor configured to generate a first signal corresponding to a physiological parameter and a controller disposed within a housing, the controller configured to evaluate the first physiological parameter signal to determine if an infection is indicated. Other embodiments are also included herein.
摘要翻译：本发明涉及用于检测与可植入医疗装置相关的感染的系统，装置和方法。在一个实施例中，本发明包括检测患者感染的方法，包括在多个时间点使用长期植入的传感器测量生理参数，并评估生理参数测量以确定是否指示感染。在一个实施例中，本发明包括可植入医疗装置，其包括被配置为产生对应于生理参数的第一信号的第一长期可植入传感器和设置在壳体内的控制器，所述控制器被配置为评估第一生理参数信号以确定是否表示感染。本文还包括其它实施例。

6. 发明授权

US07184821B2 Monitoring thoracic fluid changes 有权
标题翻译：监测胸腔改变
公开(公告)号：US07184821B2
公开(公告)日：2007-02-27
申请号：US10726949
申请日：2003-12-03
申请人： Andres Belalcazar , Robert Patterson
发明人： Andres Belalcazar , Robert Patterson
IPC分类号： A61B5/05
CPC分类号： A61B5/0537 , A61B5/0809 , A61N1/372
摘要： Changes in fluid volume in a thoracic region, such as the lung, are detected by internally injecting a current through the region, detecting an induced voltage on the skin of the patient, and calculating an impedance value. A method for performing such a measurement includes injecting an electrical current between first and second internal electrodes that are implanted in the body and that are positioned such that a portion of the injected current flows through at least a portion of the region. The method also includes measuring a voltage between first and second external electrodes attached to an external surface of the skin of the body. The measured voltage is induced by the injected current. The method also includes calculating an impedance by taking the ratio of the measured voltage and the injected current, wherein the calculated impedance is related to the volume of fluid in the region.
摘要翻译：通过在该区域内部注入电流，检测患者皮肤上的感应电压和计算阻抗值来检测胸部区域（例如肺）中的体积变化。用于执行这种测量的方法包括在注入到体内的第一和第二内部电极之间注入电流，并将其定位成使得一部分注入的电流流过该区域的至少一部分。该方法还包括测量附接到身体皮肤的外表面的第一和第二外部电极之间的电压。测量的电压由注入电流引起。该方法还包括通过获取测量电压和注入电流的比值来计算阻抗，其中所计算的阻抗与该区域中的流体体积相关。

7. 发明授权

US08983592B2 Monitoring fluid in a subject using an electrode configuration providing negative sensitivity regions 有权
公开(公告)号：US08983592B2
公开(公告)日：2015-03-17
申请号：US12621984
申请日：2009-11-19
申请人： Andres Belalcazar
发明人： Andres Belalcazar
IPC分类号： A61B5/05 , A61B5/053 , A61B5/00
CPC分类号： A61B5/0537 , A61B5/4869
摘要： An amount of fluid in a thoracic or other region of a subject may be monitored by internally injecting an electrical energy stimulus (e.g., constant voltage source) through the region, detecting voltage resulting from the electrical energy stimulus, and calculating a fluid volume indicative signal. The injected energy stimulus creates a first lead field. The responsive voltage is detected using an electrode configuration that defines a second lead field, which is arranged in a negative sensitivity configuration with respect to the first lead field at the region being monitored.

8. 发明申请

US20140031729A1 Method and Apparatus for Improved Ventilation and Cardio-Pulmonary Resuscitation 审中-公开
标题翻译：改善通气和心肺复苏的方法和装置
公开(公告)号：US20140031729A1
公开(公告)日：2014-01-30
申请号：US13751121
申请日：2013-01-27
申请人： Hugo Andres Belalcazar
发明人： Hugo Andres Belalcazar
IPC分类号： A61H31/00 , A61M16/06 , A61M16/20
CPC分类号： A61H31/00 , A61H31/004 , A61M16/06 , A61M16/0677 , A61M16/10 , A61M16/20 , A61M16/202 , A61M16/203 , A61M2202/0208 , A61M2205/332
摘要： Apparatuses and methods are disclosed for improved ventilation and cardio-pulmonary resuscitation. An apparatus of the invention may include sealing means, a valve that is configured to the sealing means to control the airway of a patient, means to actuate the valve, a control unit coupled to the valve actuating means, and means to deliver mechanical compressions to the chest. The control unit is configured to actuate the valve and the mechanical compression means to affect a number of sequences of states. Further, an apparatus of the present invention may include an oxygen source, oxygen valve, and oxygen valve actuator. Methods consistent with the afore-described apparatuses are disclosed.
摘要翻译：公开了用于改善通气和心肺复苏的装置和方法。本发明的装置可以包括密封装置，构造成用于控制患者的气道的密封装置的阀，致动阀的装置，联接到阀致动装置的控制单元，以及将机械按压传送到胸部。控制单元被配置为致动阀和机械压缩装置以影响多个状态序列。此外，本发明的装置可以包括氧源，氧气阀和氧气阀致动器。公开了与上述装置一致的方法。

9. 发明授权

US08180442B2 Deriving patient activity information from sensed body electrical information 有权
标题翻译：从检测到的身体电气信息中导出患者活动信息
公开(公告)号：US08180442B2
公开(公告)日：2012-05-15
申请号：US11956884
申请日：2007-12-14
申请人： Andres Belalcazar , Ji Chen
发明人： Andres Belalcazar , Ji Chen
IPC分类号： A61B5/04
CPC分类号： A61B5/0422 , A61B5/0031 , A61B5/4519
摘要： Electrodes of a subcutaneous monitoring system receive body electrical signals that indicate both cardiac and non-cardiac muscle activity. In general, non-cardiac muscle activity is often correlated with physical activity, and physical activity is typically a strong indicator of patient health. Exemplary systems and methods that detect non-cardiac muscle activity information in sensed body electrical waveforms may provide a diagnostic tool for monitoring physical activity level over time in patients that have subcutaneous monitoring systems. In an illustrative embodiment, systems and methods for presenting patient activity information in a graphical format over intervals of time include processing ECG waveform information to identify and to accumulate non-cardiac muscular activity information during each of the intervals of time. In various implementations, number, intensity, and/or duration of the events that are identified during a time interval may be accumulated and stored for subsequent recall.
摘要翻译：皮下监测系统的电极接收体内指示心脏和非心脏肌肉活动的电信号。一般来说，非心肌肌肉活动通常与身体活动相关，身体活动通常是患者健康的强烈指标。在检测到的身体电波形中检测非心脏肌肉活动信息的示例性系统和方法可提供用于在具有皮下监测系统的患者中随时间监测身体活动水平的诊断工具。在说明性实施例中，用于以时间间隔以图形格式呈现患者活动信息的系统和方法包括处理ECG波形信息以在每个时间间隔期间识别和累积非心脏肌肉活动信息。在各种实现中，可以累积并存储在时间间隔期间识别的事件的数量，强度和/或持续时间以用于随后的召回。

10. 发明授权

US08131356B2 Impedance monitoring for detecting pulmonary edema and thoracic congestion 有权
标题翻译：用于检测肺水肿和胸部充血的阻抗监测
公开(公告)号：US08131356B2
公开(公告)日：2012-03-06
申请号：US11936357
申请日：2007-11-07
申请人： Andres Belalcazar , Robert Patterson , Rebecca Shult
发明人： Andres Belalcazar , Robert Patterson , Rebecca Shult
IPC分类号： A61B5/05 , A61B5/02 , A61B5/08
CPC分类号： A61B5/4869 , A61B5/053 , A61B5/4878
摘要： An implantable medical device includes a housing for the implantable device that is sized for implantation in a chest region of a patient and includes a housing electrode. A left ventricular lead port is connectable to a proximal end of a lead having first and second insulated conductors that extend from the proximal end of the lead to corresponding first and second electrodes near a distal end of the lead. An electrical impedance measurement circuit is electrically connected to the left ventricular lead port and the housing electrode. The circuit may inject current between the first lead electrode and the housing electrode, and measure a voltage potential, created by the current injection, between the second lead electrode and the housing electrode. The ratio of the measured voltage to injected current may be used for assessing pulmonary edema. The lead electrodes may be located in a left ventricular coronary vein.
摘要翻译：可植入医疗装置包括用于可植入装置的壳体，其尺寸适于植入患者的胸部区域并且包括壳体电极。左心室引导端口可连接到具有从引线的近端延伸到引线远端附近的对应的第一和第二电极的第一和第二绝缘导体的引线的近端。电阻抗测量电路电连接到左心室引导端口和外壳电极。电路可以在第一引线电极和壳体电极之间注入电流，并且测量由第二引线电极和外壳电极之间的电流注入产生的电压。测量电压与注射电流的比值可用于评估肺水肿。引线电极可以位于左心室冠状静脉中。

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