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1. 发明申请

US20040127916A1 Catheter-based fastener implantation apparatus and methods with implantation force resolution 有权
标题翻译：基于导管的紧固件植入装置和具有植入力分辨率的方法
公开(公告)号：US20040127916A1
公开(公告)日：2004-07-01
申请号：US10669881
申请日：2003-09-24
申请人： Aptus Endosystems, Inc.
发明人： Lee Bolduc , Juan C. Parodi
IPC分类号： A61B017/08
CPC分类号： A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/10 , A61B2017/00398 , A61B2017/00539 , A61B2017/00544 , A61B2017/00734 , A61B2017/0647 , A61B2017/0648 , A61B2017/0649 , A61B2017/2905 , A61F2/064 , A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/065
摘要： Apparatus and methods implant a fastener in a targeted body region, e.g., a hollow body cavity or an intraluminal space. The apparatus and methods deploy in the targeted body region a fastener attachment assembly that carries an actuated member. The actuated member is selectively operable to generate an implantation force to implant a fastener into tissue within the targeted body region. The fastener can be implanted, e.g., to secure a prosthesis, e.g., an endovascular graft. The systems and apparatus apply a resolution force at or near the actuated member, thereby making possible a stable and dependable catheter-based fastening platform.
摘要翻译：装置和方法将紧固件植入目标身体区域，例如中空体腔或管腔内空间。装置和方法在目标身体区域中展开携带致动构件的紧固件附接组件。致动构件可选择性地操作以产生植入力，以将紧固件植入到目标身体区域内的组织中。紧固件可以植入，例如以固定假体，例如血管内移植物。系统和装置在致动构件处或附近施加分辨力，从而使得可能的稳定且可靠的基于导管的紧固平台成为可能。

2. 发明申请

US20040093057A1 Intraluminal prosthesis attachment systems and methods 有权
标题翻译：腔内假体附件系统和方法
公开(公告)号：US20040093057A1
公开(公告)日：2004-05-13
申请号：US10307226
申请日：2002-11-29
申请人： APTUS ENDOSYSTEMS, INC.
发明人： Lee Bolduc , Alan L. Kaganov
IPC分类号： A61F002/06
CPC分类号： A61F2/07 , A61B17/064 , A61B17/068 , A61B2017/0647 , A61B2017/0649 , A61F2/064 , A61F2/89 , A61F2/95 , A61F2002/065 , A61F2002/075
摘要： Systems and method implant prostheses in the body. The systems and methods provide permanent attachment of the prosthesis in the body. The prosthesis can comprise, e.g., an endovascular graft, which can be deployed without damaging the native blood vessel in either an arterial or a venous system. The endovascular graft can comprise, e.g., a radially expanding vascular stent and/or a stent-graft. The graft can be placed in the vasculature, e.g., to exclude or bridge an aneurysm, for example, an abdominal aortic aneurysms. The graft desirably adapts to changes in aneurysm morphology and repairs the endovascular aneurysm. The fastening systems and methods can be deployed through the vasculature and manipulated from outside the body, to deliver a fastener to attach the graft to the vessel wall.
摘要翻译：系统和方法植入假体在体内。系统和方法提供假体在体内的永久性附着。假体可以包括例如血管内移植物，其可以被部署而不损伤动脉或静脉系统中的天然血管。血管内移植物可以包括例如径向扩张的血管支架和/或支架移植物。移植物可以放置在脉管系统中，例如排除或桥接动脉瘤，例如腹主动脉瘤。移植物理想地适应动脉瘤形态的变化并修复血管内动脉瘤。紧固系统和方法可以通过脉管系统部署并从身体外部操纵，以递送紧固件以将移植物附接到血管壁。

3. 发明申请

US20140214051A1 DEVICES, SYSTEMS, AND METHODS FOR PROSTHESIS DELIVERY AND IMPLANTATION, INCLUDING THE USE OF A FASTENER TOOL 有权
标题翻译：设备，系统和方法，用于进行交付和植入，包括使用紧固件工具
公开(公告)号：US20140214051A1
公开(公告)日：2014-07-31
申请号：US14230469
申请日：2014-03-31
申请人： Aptus Endosystems, Inc.
发明人： Lee Bolduc
IPC分类号： A61F2/06
CPC分类号： A61F2/0095 , A61B17/00234 , A61B17/0401 , A61B17/068 , A61B17/105 , A61B17/3415 , A61B17/3468 , A61B2017/00292 , A61B2017/003 , A61B2017/0441 , A61B2017/0649 , A61B2017/0688 , A61B2090/3966 , A61F2/064 , A61F2/07 , A61F2/88 , A61F2/95 , A61F2/954 , A61F2002/067 , A61F2002/9511 , A61F2002/9517 , A61M25/0136 , Y10T29/49947 , Y10T29/53487 , Y10T29/53491
摘要： Devices, systems, and methods for implanting radially expandable prostheses in the body lumens rely on tacking or anchoring the prostheses with separately introduced fasteners. The prostheses may be self-expanding or balloon expandable, and may include a single lumen or more than one lumen. After initial placement, a fastener applier system is introduced within the expanded prostheses to deploy a plurality of fasteners to at least one prosthesis end. The fasteners are usually helical fasteners which are releasably restrained on the fastener driver, and are delivered by rotation of the fastener driver. The fasteners may be applied singly, typically in circumferentially spaced-apart patterns about the interior of at least one end of the prosthesis. A lumen extension or lumens may be coupled to the prosthesis to extend the reach of the prosthesis within the implantation site. Fasteners may also be applied to the lumen extensions.
摘要翻译：用于将可径向扩张的假体植入体腔内的装置，系统和方法依赖于使用单独引入的紧固件来固定或固定假体。假体可以是自膨胀或气囊扩张的，并且可以包括单个腔或多于一个腔。在初始放置之后，将紧固件施加器系统引入到扩展的假体内以将多个紧固件展开到至少一个假体末端。紧固件通常是可释放地约束在紧固件驱动器上的螺旋紧固件，并且通过紧固件驱动器的旋转而被输送。紧固件可以单独施加，通常围绕假体的至少一端的内部沿周向间隔开的图案施加。管腔延伸部或内腔可以联接到假体以延长假体在植入部位内的距离。紧固件也可以应用于管腔延伸部。

4. 发明申请

US20150127015A1 ENDOVASCULAR ANEURYSM DEVICES, SYSTEMS, AND METHODS 审中-公开
标题翻译：内分泌神经元装置，系统和方法
公开(公告)号：US20150127015A1
公开(公告)日：2015-05-07
申请号：US14595928
申请日：2015-01-13
申请人： Aptus Endosystems, Inc.
发明人： Lee Bolduc , Andrew L Chiang , Jimmy Jen , Joshua Stafford
IPC分类号： A61F2/954 , A61F2/966 , A61F2/07
CPC分类号： A61F2/954 , A61B17/064 , A61B17/068 , A61B2017/0649 , A61B2017/0688 , A61F2/0095 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2/966 , A61F2002/067 , A61F2002/075 , A61F2002/30617 , A61F2002/9511 , A61F2002/9517 , A61F2250/0097 , A61M39/06 , A61M2039/062 , A61M2039/066
摘要： Devices, systems, and methods for implanting prostheses in the body lumens rely on tacking or anchoring the prostheses with separately introduced fasteners. After initial placement, a fastener applier system is introduced within the expanded prostheses to deploy a plurality of fasteners to at least one prosthesis end. The fasteners are usually helical fasteners which are releasably restrained on the fastener driver, and are delivered by rotation of the fastener driver. The fasteners may be applied singly, typically in circumferentially spaced-apart patterns about the interior of at least one end of the prosthesis. A lumen extension or lumens may be coupled to the prosthesis to extend the reach of the prosthesis within the implantation site. Fasteners may also be applied to the lumen extensions.
摘要翻译：用于将假体植入体腔内的装置，系统和方法依赖于使用单独引入的紧固件固定假体。在初始放置之后，将紧固件施加器系统引入到扩展的假体内以将多个紧固件展开到至少一个假体末端。紧固件通常是可释放地约束在紧固件驱动器上的螺旋紧固件，并且通过紧固件驱动器的旋转而被输送。紧固件可以单独施加，通常围绕假体的至少一端的内部沿周向间隔开的图案施加。管腔延伸部或内腔可以联接到假体以延长假体在植入部位内的距离。紧固件也可以应用于管腔延伸部。

5. 发明申请

US20140194902A1 SYSTEMS AND METHODS FOR ATTACHING A PROSTHESIS WITHIN A BODY LUMEN OR HOLLOW ORGAN 有权
标题翻译：用于连接体内或身体中的前体的系统和方法
公开(公告)号：US20140194902A1
公开(公告)日：2014-07-10
申请号：US14210683
申请日：2014-03-14
申请人： Aptus Endosystems, Inc.
发明人： Lee Bolduc , Phil Houle
IPC分类号： A61B17/10
CPC分类号： A61B17/10 , A61B17/064 , A61B17/068 , A61B17/08 , A61B17/083 , A61B17/115 , A61B2017/0649 , A61B2090/037 , A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/072 , A61F2002/075 , A61F2220/0016 , A61F2250/0017
摘要： Systems and methods introduce and deploy prosthesis into a blood vessel or hollow body organ by intra-vascular access. The prosthesis is secured in place by fasteners which are implanted by an applier that is also deployed by intra-vascular access. The applier is configured to permit controlled, selective release of the fastener in a step that is independent of the step of implantation.
摘要翻译：系统和方法通过血管内通路将假体引入和部署到血管或中空身体器官中。假体通过紧固件固定在一起，该紧固件由还通过血管内通路部署的施放器植入。施加器构造成允许在独立于植入步骤的步骤中可控制选择性地释放紧固件。

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