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1. 发明授权

US09533164B2 Method for providing multiple voltage levels during pulse generation and implantable pulse generating employing the same 有权
标题翻译：在脉冲生成期间提供多个电压电平的方法以及采用该多个电压电平的可植入脉冲发生方法
公开(公告)号：US09533164B2
公开(公告)日：2017-01-03
申请号：US12245208
申请日：2008-10-03
申请人： John H. Erickson , Robert L. McCormick , Benjamin A. Tranchina
发明人： John H. Erickson , Robert L. McCormick , Benjamin A. Tranchina
IPC分类号： A61N1/378
CPC分类号： A61N1/378 , A61N1/3787
摘要： In one embodiment, a method of operating an implantable pulse generator comprises: providing power to a voltage converter at a first voltage level; outputting a second voltage level by the voltage converter, the second voltage level being a variable voltage level that is controlled by a control signal provided to the voltage converter, the second voltage level being provided to pulse generating circuitry of the implantable pulse generator, the second voltage level being selectable from a plurality of voltages including non-integer multiples of the first voltage level; generating pulses by the pulse generating circuitry, the pulse generating circuitry including current control circuitry for controlling the pulses to cause the pulses to provide substantially constant current to tissue of the patient; and applying at least two different control signals to the voltage converter during individual pulses to provide successively increasing voltages to the pulse generating circuitry during a respective pulse.
摘要翻译：在一个实施例中，一种操作可植入脉冲发生器的方法包括：在第一电压电平下向电压转换器供电; 由所述电压转换器输出第二电压电平，所述第二电压电平是由提供给所述电压转换器的控制信号控制的可变电压电平，所述第二电压电平被提供给所述可植入脉冲发生器的脉冲发生电路，所述第二电压电平电压电平可从包括第一电压电平的非整数倍的多个电压中选择; 由脉冲发生电路产生脉冲，脉冲发生电路包括电流控制电路，用于控制脉冲以使脉冲向患者的组织提供基本恒定的电流; 以及在单个脉冲期间将至少两个不同的控制信号施加到所述电压转换器，以在相应脉冲期间向所述脉冲发生电路提供连续增加的电压。

2. 发明授权

US07571007B2 Systems and methods for use in pulse generation 有权
标题翻译：用于脉冲发生的系统和方法
公开(公告)号：US07571007B2
公开(公告)日：2009-08-04
申请号：US11420670
申请日：2006-05-26
申请人： John H. Erickson , Anthony J. Varrichio , Benjamin A. Tranchina
发明人： John H. Erickson , Anthony J. Varrichio , Benjamin A. Tranchina
IPC分类号： A61N1/378
CPC分类号： A61N1/3787
摘要： In one embodiment, an implantable medical device comprises: a rechargeable battery for powering the implantable medical device; an antenna for receiving RF power; and circuitry for charging the rechargeable battery using power received via the antenna, wherein the circuitry for charging comprises control circuitry that causes the circuitry for charging to recharge the rechargeable battery using multiple current levels applied in succession, and wherein the circuitry for charging switches from at least one of the current levels to another current level when a charging voltage of the rechargeable battery reaches a threshold value that is varied by the control circuitry over a lifespan of the rechargeable battery.
摘要翻译：在一个实施例中，可植入医疗装置包括：用于为可植入医疗装置供电的可再充电电池; 用于接收RF功率的天线; 以及用于通过天线接收的功率对可再充电电池充电的电路，其中用于充电的电路包括控制电路，其使所述电路进行充电以使用连续施加的多个电流电平对所述可充电电池进行再充电，并且其中所述用于从当可再充电电池的充电电压达到在可再充电电池的寿命期间由控制电路改变的阈值时，当前电平中的至少一个电平达到另一电流水平。

3. 发明申请

US20120286841A1 PULSE GENERATOR HAVING AN EFFICIENT FRACTIONAL VOLTAGE CONVERTER AND METHOD OF USE 有权
标题翻译：具有有效的电压转换器的脉冲发生器及其使用方法
公开(公告)号：US20120286841A1
公开(公告)日：2012-11-15
申请号：US13470764
申请日：2012-05-14
申请人： Benjamin A. Tranchina , John H. Erickson , Anthony J. Varrichio
发明人： Benjamin A. Tranchina , John H. Erickson , Anthony J. Varrichio
IPC分类号： H03K3/02
CPC分类号： A61N1/025 , H02M3/07
摘要： Disclosed are systems and methods which provide voltage conversion in increments less than integer multiples of a power supply (e.g., battery) voltage. A representative embodiment provides power supply voltage multipliers in a binary ladder distribution to provide a desired number of output voltage steps using a relatively uncomplicated circuit design. By using different sources in various combinations and/or by “stacking” different sources in various ways, the voltage multiplier circuit may be used to provide desired voltages. In order to minimize the number of components used in a voltage converter of an embodiment, a capacitive voltage converter circuit uses one or more storage capacitors in place of pump capacitors in a voltage generation cycle. Also, certain embodiments do not operate to generate an output voltage until the time that voltage is needed.
摘要翻译：公开了以小于电源（例如，电池）电压的整数倍的增量提供电压转换的系统和方法。代表性的实施例提供二进制梯形分布中的电源电压倍增器，以使用相对简单的电路设计提供期望数量的输出电压步长。通过以各种组合使用不同的源和/或以各种方式堆叠不同的源，可以使用电压倍增器电路来提供期望的电压。为了最小化实施例的电压转换器中使用的部件的数量，电容性电压转换器电路在电压产生循环中使用一个或多个存储电容器代替泵电容器。而且，某些实施例在直到需要电压的时间之前不会产生输出电压。

4. 发明授权

US08179190B2 Pulse generator having an efficient fractional voltage converter and method of use 有权
$Pulse generator having an efficient fractional voltage converter and method of use$
标题翻译：脉冲发生器具有有效的分数电压转换器和使用方法
公开(公告)号：US08179190B2
公开(公告)日：2012-05-15
申请号：US13185114
申请日：2011-07-18
申请人： Benjamin A Tranchina , John H Erickson , Anthony J Varrichio
发明人： Benjamin A Tranchina , John H Erickson , Anthony J Varrichio
IPC分类号： G05F1/10 , G05F3/02
CPC分类号： A61N1/025 , H02M3/07
摘要： Disclosed are systems and methods which provide voltage conversion in increments less than integer multiples of a power supply (e.g., battery) voltage. A representative embodiment provides power supply voltage multipliers in a binary ladder distribution to provide a desired number of output voltage steps using a relatively uncomplicated circuit design. By using different sources in various combinations and/or by “stacking” different sources in various ways, the voltage multiplier circuit may be used to provide desired voltages. In order to minimize the number of components used in a voltage converter of an embodiment, a capacitive voltage converter circuit uses one or more storage capacitors in place of pump capacitors in a voltage generation cycle. Also, certain embodiments do not operate to generate an output voltage until the time that voltage is needed.
摘要翻译：公开了以小于电源（例如，电池）电压的整数倍的增量提供电压转换的系统和方法。代表性的实施例提供二进制梯形分布中的电源电压倍增器，以使用相对简单的电路设计提供期望数量的输出电压步长。通过以各种方式使用不同的源和/或以不同的方式“堆叠”不同的源，可以使用电压倍增器电路来提供期望的电压。为了最小化实施例的电压转换器中使用的部件的数量，电容性电压转换器电路在电压产生循环中使用一个或多个存储电容器代替泵电容器。而且，某些实施例在直到需要电压的时间之前不会产生输出电压。

5. 发明申请

US20090048643A1 METHOD FOR PROVIDING MULTIPLE VOLTAGE LEVELS DURING PULSE GENERATION AND IMPLANTABLE PULSE GENERATING EMPLOYING THE SAME 有权
标题翻译：在脉冲发生过程中提供多个电压水平的方法和使用其的可植入脉冲生成方法
公开(公告)号：US20090048643A1
公开(公告)日：2009-02-19
申请号：US12245208
申请日：2008-10-03
申请人： John H. Erickson , Robert L. McCormick , Benjamin A. Tranchina
发明人： John H. Erickson , Robert L. McCormick , Benjamin A. Tranchina
IPC分类号： A61N1/36
CPC分类号： A61N1/378 , A61N1/3787
摘要： In one embodiment, a method of operating an implantable pulse generator comprises: providing power to a voltage converter at a first voltage level; outputting a second voltage level by the voltage converter, the second voltage level being a variable voltage level that is controlled by a control signal provided to the voltage converter, the second voltage level being provided to pulse generating circuitry of the implantable pulse generator, the second voltage level being selectable from a plurality of voltages including non-integer multiples of the first voltage level; generating pulses by the pulse generating circuitry, the pulse generating circuitry including current control circuitry for controlling the pulses to cause the pulses to provide substantially constant current to tissue of the patient; and applying at least two different control signals to the voltage converter during individual pulses to provide successively increasing voltages to the pulse generating circuitry during a respective pulse.
摘要翻译：在一个实施例中，一种操作可植入脉冲发生器的方法包括：在第一电压电平下向电压转换器供电; 由所述电压转换器输出第二电压电平，所述第二电压电平是由提供给所述电压转换器的控制信号控制的可变电压电平，所述第二电压电平被提供给所述可植入脉冲发生器的脉冲发生电路，所述第二电压电平电压电平可从包括第一电压电平的非整数倍的多个电压中选择; 由脉冲发生电路产生脉冲，脉冲发生电路包括电流控制电路，用于控制脉冲以使脉冲向患者的组织提供基本恒定的电流; 以及在单个脉冲期间将至少两个不同的控制信号施加到所述电压转换器，以在相应脉冲期间向所述脉冲发生电路提供连续增加的电压。

6. 发明授权

US07180760B2 Method of efficiently performing fractional voltage conversion and system comprising efficient fractional voltage converter circuitry 有权
$Method of efficiently performing fractional voltage conversion and system comprising efficient fractional voltage converter circuitry$
标题翻译：有效执行分数电压转换的方法和包括有效分数电压转换器电路的系统
公开(公告)号：US07180760B2
公开(公告)日：2007-02-20
申请号：US11105332
申请日：2005-04-12
申请人： Anthony J. Varrichio , Benjamin A. Tranchina
发明人： Anthony J. Varrichio , Benjamin A. Tranchina
IPC分类号： H02M3/18 , H02M7/00
CPC分类号： A61N1/36153 , A61N1/36125 , A61N1/3782 , H02M3/07 , H02M2003/072
摘要： Embodiments provide a capacitive voltage multiplier for efficiently producing multiples, including fractional multiples, of a power supply voltage use high, medium and low voltage field effect transistors for switching terminals of various capacitors into and out of connection with power supply or ground voltages in charge mode and with an output or other capacitor terminals for series connection in pump mode. A single non-overlapping clock is level-shifted up to the maximum voltage level required for switching to produce a desired output, then level shifted back down to lower levels with delay added as necessary according to embodiments.
摘要翻译：实施例提供一种用于有效地产生电源电压的倍数（包括分数倍）的电容电压倍增器，其使用高，中和低电压场效应晶体管，用于将各种电容器的端子切换到与电源或充电模式中的接地电压相关联并具有用于泵模式串联连接的输出或其他电容器端子。单个不重叠的时钟被电平移位直到切换产生期望的输出所需的最大电压电平，然后根据实施例根据需要将电平移位回到较低的电平并根据需要进行延迟。

7. 发明申请

US20110273225A1 PULSE GENERATOR HAVING AN EFFICIENT FRACTIONAL VOLTAGE CONVERTER AND METHOD OF USE 有权
标题翻译：具有有效的电压转换器的脉冲发生器及其使用方法
公开(公告)号：US20110273225A1
公开(公告)日：2011-11-10
申请号：US13185114
申请日：2011-07-18
申请人： Benjamin A. Tranchina , John H. Erickson , Anthony J. Varrichio
发明人： Benjamin A. Tranchina , John H. Erickson , Anthony J. Varrichio
IPC分类号： G05F1/10
CPC分类号： A61N1/025 , H02M3/07
摘要： Disclosed are systems and methods which provide voltage conversion in increments less than integer multiples of a power supply (e.g., battery) voltage. A representative embodiment provides power supply voltage multipliers in a binary ladder distribution to provide a desired number of output voltage steps using a relatively uncomplicated circuit design. By using different sources in various combinations and/or by “stacking” different sources in various ways, the voltage multiplier circuit may be used to provide desired voltages. In order to minimize the number of components used in a voltage converter of an embodiment, a capacitive voltage converter circuit uses one or more storage capacitors in place of pump capacitors in a voltage generation cycle. Also, certain embodiments do not operate to generate an output voltage until the time that voltage is needed.
摘要翻译：公开了以小于电源（例如，电池）电压的整数倍的增量提供电压转换的系统和方法。代表性的实施例提供二进制梯形分布中的电源电压倍增器，以使用相对简单的电路设计提供期望数量的输出电压步长。通过以各种方式使用不同的源和/或以不同的方式“堆叠”不同的源，可以使用电压倍增器电路来提供期望的电压。为了最小化实施例的电压转换器中使用的部件的数量，电容性电压转换器电路在电压产生循环中使用一个或多个存储电容器代替泵电容器。而且，某些实施例在直到需要电压的时间之前不会产生输出电压。

8. 发明授权

US07949393B2 Implantable pulse generator comprising fractional voltage converter 有权
$Implantable pulse generator comprising fractional voltage converter$
标题翻译：包括分数电压转换器的可植入式脉冲发生器
公开(公告)号：US07949393B2
公开(公告)日：2011-05-24
申请号：US12817659
申请日：2010-06-17
申请人： Anthony J Varrichio , Benjamin A Tranchina
发明人： Anthony J Varrichio , Benjamin A Tranchina
IPC分类号： A61N1/00
CPC分类号： A61N1/36153 , A61N1/36125 , A61N1/3782 , H02M3/07 , H02M2003/072
摘要： In one embodiment, an implantable pulse generator comprises: pulse generating circuitry for generating pulses and delivering the pulses to outputs of the implantable pulse generator; a controller; wherein the pulse generating circuitry comprises a voltage multiplier for multiplying a battery voltage, the voltage multiplier including multiple outputs, wherein a first output of the multiple outputs provides a voltage that is programmably selectable from a plurality of voltages including non-integer multiples of the battery voltage, wherein a second output of the multiple outputs provides a voltage that is a fixed multiple of the battery voltage; wherein the controller controls the pulse generator circuitry to generate a first pulse for stimulation of the patient using a first output of the multiple outputs and controls the pulse generator circuitry to generate a second pulse to discharge output capacitors of residual charge from the first pulse using a second output of the multiple outputs.
摘要翻译：在一个实施例中，可植入脉冲发生器包括：脉冲发生电路，用于产生脉冲并将脉冲传送到可植入脉冲发生器的输出; 控制器其中所述脉冲发生电路包括用于乘以电池电压的电压倍增器，所述电压倍增器包括多个输出，其中所述多个输出的第一输出提供可从包括所述电池的非整数倍的多个电压可编程地选择的电压电压，其中所述多个输出的第二输出提供作为所述电池电压的固定倍数的电压; 其中所述控制器控制所述脉冲发生器电路以使用所述多个输出的第一输出来产生用于刺激所述患者的第一脉冲，并且控制所述脉冲发生器电路以产生第二脉冲，以使用第一脉冲从所述第一脉冲放电剩余电荷的输出电容器第二输出的多路输出。

9. 发明申请

US20100256712A1 IMPLANTABLE PULSE GENERATOR COMPRISING FRACTIONAL VOLTAGE CONVERTER 有权
标题翻译：包含有电压转换器的可插拔脉冲发生器
公开(公告)号：US20100256712A1
公开(公告)日：2010-10-07
申请号：US12817659
申请日：2010-06-17
申请人： Anthony J. Varrichio , Benjamin A. Tranchina
发明人： Anthony J. Varrichio , Benjamin A. Tranchina
IPC分类号： A61N1/36
CPC分类号： A61N1/36153 , A61N1/36125 , A61N1/3782 , H02M3/07 , H02M2003/072
摘要： In one embodiment, an implantable pulse generator comprises: pulse generating circuitry for generating pulses and delivering the pulses to outputs of the implantable pulse generator; a controller; wherein the pulse generating circuitry comprises a voltage multiplier for multiplying a battery voltage, the voltage multiplier including multiple outputs, wherein a first output of the multiple outputs provides a voltage that is programmably selectable from a plurality of voltages including non-integer multiples of the battery voltage, wherein a second output of the multiple outputs provides a voltage that is a fixed multiple of the battery voltage; wherein the controller controls the pulse generator circuitry to generate a first pulse for stimulation of the patient using a first output of the multiple outputs and controls the pulse generator circuitry to generate a second pulse to discharge output capacitors of residual charge from the first pulse using a second output of the multiple outputs.
摘要翻译：在一个实施例中，可植入脉冲发生器包括：脉冲发生电路，用于产生脉冲并将脉冲传送到可植入脉冲发生器的输出; 控制器其中所述脉冲发生电路包括用于乘以电池电压的电压倍增器，所述电压倍增器包括多个输出，其中所述多个输出的第一输出提供可从包括所述电池的非整数倍的多个电压可编程地选择的电压电压，其中所述多个输出的第二输出提供作为所述电池电压的固定倍数的电压; 其中所述控制器控制所述脉冲发生器电路以使用所述多个输出的第一输出来产生用于刺激所述患者的第一脉冲，并且控制所述脉冲发生器电路以产生第二脉冲，以使用第一脉冲从所述第一脉冲放电剩余电荷的输出电容器第二输出的多路输出。

10. 发明申请

US20080228236A1 ACTIVE DISCHARGE SYSTEMS AND METHODS 有权
标题翻译：主动放电系统和方法
公开(公告)号：US20080228236A1
公开(公告)日：2008-09-18
申请号：US12127551
申请日：2008-05-27
申请人： Anthony J. Varrichio , Benjamin A. Tranchina
发明人： Anthony J. Varrichio , Benjamin A. Tranchina
IPC分类号： A61N1/08
CPC分类号： A61N1/36146 , A61N1/14 , A61N1/36125 , A61N1/3782
摘要： To avoid charge accumulation on capacitive connections to implanted electrodes during delivery of stimulation pulses, stimulation pulses are followed by active discharge pulses having opposite polarity of the stimulation pulses. The active discharge pulses preferably have at least one pulse attribute magnitude (e.g., duration, voltage, and/or current) different than a corresponding stimulation pulse and are preferably programmable. Approximately the same total net current flow is delivered during active discharge pulses as during the stimulation pulses, but in the opposite direction and optionally at a lower amplitude. In addition, by reducing the driving voltage and a variable load within the electrical path for delivery of the pulses, power dissipation during active discharge is preferably reduced.
摘要翻译：为了避免在递送刺激脉冲期间对植入电极的电容连接上的电荷积累，刺激脉冲之后是具有相反极性的刺激脉冲的有效放电脉冲。有效放电脉冲优选地具有与相应的刺激脉冲不同的至少一个脉冲属性量值（例如，持续时间，电压和/或电流），并且优选地是可编程的。在激活脉冲期间，在激活的放电脉冲期间传递大约相同的总净电流，但是在相反方向，并且可选地以较低的振幅。此外，通过降低驱动电压和用于传送脉冲的电路内的可变负载，优选地减少有效放电期间的功率耗散。

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