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1. 发明授权

US09468745B2 Apparatus and methods for inflating and deflating balloon catheters 有权
标题翻译：用于充气和放气气球导管的装置和方法
公开(公告)号：US09468745B2
公开(公告)日：2016-10-18
申请号：US13978230
申请日：2012-01-04
申请人： Celso J. Bagaoisan , Glen Gong , Suresh Pai , Scott Robert Sershen
发明人： Celso J. Bagaoisan , Glen Gong , Suresh Pai , Scott Robert Sershen
IPC分类号： A61M25/10
CPC分类号： A61M25/10182 , A61M25/10184 , F04C2270/041
摘要： Among the various embodiments, objects and features of the present invention may generally be noted an inflation/deflation syringe that enables one-handed operation to inflate a medical device to a given pressure or volume and one-handed operation to deflate said medical device.
摘要翻译：在各种实施例中，本发明的目的和特征通常可以注意到使充气/放气注射器能够单手操作以将医疗装置充气到给定的压力或体积，并且单手操作以使所述医疗装置放气。

2. 发明授权

US08945178B2 Apparatus and methods for sealing a vascular puncture 有权
标题翻译：用于密封血管穿刺的装置和方法
公开(公告)号：US08945178B2
公开(公告)日：2015-02-03
申请号：US13610849
申请日：2012-09-11
申请人： Suresh S. Pai , Celso J. Bagaoisan , Farhad Khosravi
发明人： Suresh S. Pai , Celso J. Bagaoisan , Farhad Khosravi
IPC分类号： A61B17/03 , A61B17/00
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00495 , A61B2017/00637 , A61B2017/0065 , A61B2017/00672
摘要： Apparatus for sealing a puncture through tissue to a blood vessel includes a cartridge including a proximal end, a distal end sized for insertion into a puncture, and a lumen extending therebetween. A bioabsorbable plug is disposed within the lumen adjacent the distal end, and an anchoring element is disposed within the lumen proximal to the plug. A pusher member is disposed within the lumen for deploying the plug and anchoring element out the distal end of the cartridge. The plug may be formed from lyophilized hydrogel and the anchoring element may be formed from air-dried hydrogel, the anchoring element hydrating slower than the plug when exposed to an aqueous environment. During use, the plug and anchoring element are delivered into the puncture, the plug is cinched against the vessel wall. Protrusions on the anchoring element engage tissue surrounding the puncture to prevent proximal movement of the plug.
摘要翻译：用于将穿过组织的穿刺密封到血管的装置包括：盒，其包括近端，尺寸适于插入穿刺的远端以及在其间延伸的内腔。生物可吸收塞子设置在邻近远端的内腔内，并且锚定元件设置在靠近塞子的内腔内。推动器构件设置在内腔内，用于将插塞和锚固元件从盒的远端伸出。塞子可以由冻干的水凝胶形成，并且锚定元件可以由空气干燥的水凝胶形成，当暴露于水性环境时，锚定元件比塞子保持缓慢。在使用过程中，插头和锚定元件被输送到穿刺部分中，塞子紧贴在血管壁上。锚固元件上的突起接合穿刺周围的组织，以防止插塞的近端移动。

3. 发明授权

US08128654B2 Apparatus and methods for sealing a vascular puncture 有权
标题翻译：用于密封血管穿刺的装置和方法
公开(公告)号：US08128654B2
公开(公告)日：2012-03-06
申请号：US11929728
申请日：2007-10-30
申请人： Farhad Khosravi , Celso J. Bagaoisan , Stephen Ramee
发明人： Farhad Khosravi , Celso J. Bagaoisan , Stephen Ramee
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00557 , A61B2017/00637 , A61B2017/0065 , A61M25/10182 , A61M25/10187 , A61M2025/0681
摘要： An apparatus for sealing a puncture communicating with a blood vessel includes an inner member slidable within an outer member, and a balloon coupled to distal ends of the inner and outer members. A proximal end of the outer member includes a port for delivering fluid into the balloon, and a cylinder that communicates with the port. A piston coupled to the inner member is slidable and biased to move distally within the cylinder. The apparatus is introduced into the puncture until the collapsed balloon is disposed within the vessel. Fluid is introduced into the port, moving the inner member proximally to shorten the balloon as it expands. The balloon is withdrawn to seal the puncture, and a hydrogel is introduced into the puncture. Fluid is removed via the port, moving the inner member distally to extend the balloon as it collapses, and the apparatus is withdrawn.
摘要翻译：用于密封与血管连通的穿刺的装置包括可在外部构件内滑动的内部构件和联接到内部构件和外部构件的远端的气囊。外部构件的近端包括用于将流体输送到气囊中的端口和与端口连通的气缸。联接到内部构件的活塞可滑动并且被偏压以在气缸内向远侧移动。该装置被引入到穿刺中，直到塌陷的气囊被置于血管内。将流体引入端口中，使内部构件向近端移动，以在气囊膨胀时缩短气囊。撤回气囊以密封穿刺，并将水凝胶引入穿刺中。通过端口移除流体，使内部构件向远端移动，以在气囊塌缩时延伸气囊，并且退出设备。

4. 发明授权

US07985240B2 Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture 有权
标题翻译：闭塞成员和张紧器设备及其用于密封血管穿刺的方法
公开(公告)号：US07985240B2
公开(公告)日：2011-07-26
申请号：US11929762
申请日：2007-10-30
申请人： Celso J. Bagaoisan , Juan Domingo , Nicanor Domingo , Farhad Khosravi , Suresh S. Pai
发明人： Celso J. Bagaoisan , Juan Domingo , Nicanor Domingo , Farhad Khosravi , Suresh S. Pai
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00557 , A61B2017/00637 , A61B2017/0065 , A61M25/10182 , A61M25/10187 , A61M2025/0681
摘要： Apparatus for sealing a puncture includes an elongate occlusion member having a balloon attached to distal ends of telescoping inner and outer members. A housing on the proximal end of the outer member includes a piston coupled to the inner member and slidable within a chamber communicating with a fluid reservoir. A switch on the housing is actuated to direct fluid from the reservoir through the outer member into the balloon to expand the balloon and into the chamber to move the piston and pull the inner member, shortening the balloon as it expands. During use, the distal end of the occlusion member is introduced into a puncture communicating with a vessel until the collapsed balloon is disposed within the vessel. The balloon is expanded, and a tensioner is connected to the housing to apply a proximal force holding the balloon against the vessel wall to seal the puncture.
摘要翻译：用于密封穿刺的装置包括具有附接到伸缩的内部和外部构件的远端的气囊的细长闭塞构件。外部构件的近端上的壳体包括联接到内部构件并可在与流体储存器连通的腔室内滑动的活塞。启动壳体上的开关以将流体从储存器引导通过外部构件进入气囊，以使气囊膨胀并进入腔室中，以移动活塞并拉动内部构件，从而在气囊膨胀时缩短气囊。在使用期间，将阻塞构件的远端引入到与血管连通的穿刺件中，直到将收缩的气囊设置在血管内。气囊膨胀，并且张紧器连接到壳体以施加将气囊保持抵靠血管壁的近侧力以密封穿刺。

5. 发明申请

US20100168789A1 APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE 有权
标题翻译：用于密封血管内窥镜的装置和方法
公开(公告)号：US20100168789A1
公开(公告)日：2010-07-01
申请号：US12617693
申请日：2009-11-12
申请人： Celso J. Bagaoisan , Juan Domingo , Sieu Duong
发明人： Celso J. Bagaoisan , Juan Domingo , Sieu Duong
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/0065 , A61B2017/00654 , A61B2017/00893 , A61B2017/00898 , A61B2090/034 , A61B2090/0811
摘要： An apparatus for sealing a puncture includes a cartridge, a pusher member, a sealant, and a tamping device on a proximal end of the cartridge. During use, the cartridge, sealant, and pusher member are advanced over a positioning member and into the puncture by advancing a cartridge hub carrying the tamping device. When further distal advancement of the cartridge is limited, the cartridge hub is further advanced, activating the tamping device, and causing the pusher member to advance relative to the sealant to compress the sealant within the puncture.
摘要翻译：用于密封穿刺的装置包括在药筒的近端上的药筒，推动器构件，密封剂和捣固装置。在使用期间，盒，密封剂和推动器构件通过推进承载捣固装置的盒毂而前进到定位构件并进入穿刺。当盒的进一步的远侧前进受到限制时，盒轮毂进一步前进，启动捣固装置，并且使推动器构件相对于密封剂前进以压缩穿刺内的密封剂。

6. 发明授权

US07331979B2 Apparatus and methods for sealing a vascular puncture 有权
标题翻译：用于密封血管穿刺的装置和方法
公开(公告)号：US07331979B2
公开(公告)日：2008-02-19
申请号：US10454362
申请日：2003-06-04
申请人： Farhad Khosravi , Celso J. Bagaoisan , Stephen Ramee
发明人： Farhad Khosravi , Celso J. Bagaoisan , Stephen Ramee
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00557 , A61B2017/00637 , A61B2017/0065 , A61M25/10182 , A61M25/10187 , A61M2025/0681
摘要： An apparatus for sealing a puncture communicating with a blood vessel includes an inner member slidable within an outer member, and a balloon coupled to distal ends of the inner and outer members. A proximal end of the outer member includes a port for delivering fluid into the balloon, and a cylinder that communicates with the port. A piston coupled to the inner member is slidable and biased to move distally within the cylinder. The apparatus is introduced into the puncture until the collapsed balloon is disposed within the vessel. Fluid is introduced into the port, moving the inner member proximally to shorten the balloon as it expands. The balloon is withdrawn to seal the puncture, and a hydrogel is introduced into the puncture. Fluid is removed via the port, moving the inner member distally to extend the balloon as it collapses, and the apparatus is withdrawn from the puncture.
摘要翻译：用于密封与血管连通的穿刺的装置包括可在外部构件内滑动的内部构件和联接到内部构件和外部构件的远端的气囊。外部构件的近端包括用于将流体输送到气囊中的端口和与端口连通的气缸。联接到内部构件的活塞可滑动并且被偏压以在气缸内向远侧移动。该装置被引入到穿刺中，直到塌陷的气囊被置于血管内。将流体引入端口中，使内部构件向近端移动，以在气囊膨胀时缩短气囊。撤回气囊以密封穿刺，并将水凝胶引入穿刺中。通过端口移除流体，使内部构件向远侧移动，以在气囊塌缩时延伸气囊，并且将设备从穿刺中取出。

7. 发明授权

US06786888B1 Low profile catheter for emboli protection 失效
标题翻译：低剖面导管用于栓塞保护
公开(公告)号：US06786888B1
公开(公告)日：2004-09-07
申请号：US09684186
申请日：2000-10-06
申请人： Gholam-Reza Zadno-Azizi , Celso J. Bagaoisan , Jefferey C. Bleam
发明人： Gholam-Reza Zadno-Azizi , Celso J. Bagaoisan , Jefferey C. Bleam
IPC分类号： A61M2900
CPC分类号： A61M25/10185 , A61M25/0009 , A61M25/0026 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/104 , A61M2025/0018 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1052 , A61M2025/1079 , A61M2025/1093
摘要： A low profile catheter valve comprises a movable sealer portion positioned within the inflation lumen of a catheter. The sealer portion forms a fluid tight seal with the inflation lumen by firmly contacting the entire circumference of a section of the inflation lumen. The sealer portion may be positioned proximally of a side-access inflation port on the catheter, to establish an unrestricted fluid pathway between the inflation port and an inflatable balloon on the distal end of the catheter. As desired, the clinician may move the sealer portion to a position distal of the inflation port, thereby preventing any fluid from being introduced into or withdrawn from the balloon via the inflation port.
摘要翻译：低剖面导管阀包括位于导管的充气腔内的可移动密封件部分。密封器部分通过牢固地接触充气腔的一部分的整个周边而与充气腔形成流体密封的密封。密封器部分可以位于导管上的侧向通过充气端口的近侧，以在充气端口和导管远端上的可充气气囊之间建立不受限制的流体通路。根据需要，临床医生可以将密封部分移动到充气端口的远侧位置，从而防止任何流体经由充气口引入或从气囊中排出。

8. 发明授权

US06500166B1 Method of emboli protection using a low profile catheter 失效
标题翻译：使用低剖面导管的栓塞保护方法
公开(公告)号：US06500166B1
公开(公告)日：2002-12-31
申请号：US09455878
申请日：1999-12-06
申请人： Gholam-Reza Zadno Azizi , Celso J. Bagaoisan , Jefferey C. Bleam
发明人： Gholam-Reza Zadno Azizi , Celso J. Bagaoisan , Jefferey C. Bleam
IPC分类号： A61M3100
CPC分类号： A61M25/10185 , A61M25/0009 , A61M25/0026 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/104 , A61M2025/0018 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1052 , A61M2025/1079 , A61M2025/1093
摘要： Disclosed herein is a low profile catheter valve comprising a movable sealer portion positioned within the inflation lumen of a catheter. The sealer portion forms a fluid tight seal with the inflation lumen by firmly contacting the entire circumference of a section of the inflation lumen. The sealer portion may be positioned proximally of a side-access inflation port on the catheter, to establish an unrestricted fluid pathway between the inflation port and an inflatable balloon on the distal end of the catheter. As desired, the clinician may move the sealer portion to a position distal of the inflation port, thereby preventing any fluid from being introduced into or withdrawn from the balloon via the inflation port.
摘要翻译：本文公开了一种低剖面导管阀，其包括位于导管的充气腔内的可移动的密封部分。密封器部分通过牢固地接触充气腔的一部分的整个周边而与充气腔形成流体密封的密封。密封器部分可以位于导管上的侧向通过充气端口的近侧，以在充气端口和导管远端上的可充气气囊之间建立不受限制的流体通路。根据需要，临床医生可以将密封部分移动到充气端口的远侧位置，从而防止任何流体经由充气口引入或从气囊中排出。

9. 发明授权

US06234996B1 Integrated inflation/deflation device and method 失效
标题翻译：综合通货膨胀/通货紧缩手段及方法
公开(公告)号：US06234996B1
公开(公告)日：2001-05-22
申请号：US09338375
申请日：1999-06-23
申请人： Celso J. Bagaoisan , George Tsai , Samuel L. Omaleki , Roy Leguidleguid , Gholam-Reza Zadno-Azizi
发明人： Celso J. Bagaoisan , George Tsai , Samuel L. Omaleki , Roy Leguidleguid , Gholam-Reza Zadno-Azizi
IPC分类号： A61M2900
CPC分类号： A61M25/10182 , A61M5/31505 , A61M5/31566 , A61M5/31586 , A61M25/1018 , A61M25/10185 , A61M25/104 , A61M39/06 , A61M2005/14573
摘要： An integrated inflation/deflation device provides easy, precise delivery of a small amount of fluid for proper inflation of a low volume surgical balloon and similarly provides easy and fast deflation of the balloon. A preferred embodiment includes a low volume syringe and large syringe mounted together within a housing. A port in the low volume syringe is in communication with the large syringe barrel. The low volume syringe plunger is controlled by a knob disposed on the housing. The large syringe is used to prime the surgical balloon system, including a catheter, and the low volume syringe delivers a precise, predetermined volume of fluid to inflate the balloon. The low volume syringe is also used to deflate the balloon. Preferably, indicia on the housing adjacent the knob direct the required rotation of the knob to deliver the correct volume of fluid to be injected to match a balloon of a given size and shape so that the balloon is properly inflated.
摘要翻译：综合的充气/放气装置提供了容易，精确地输送少量流体以适当地膨胀低容量手术气囊，并且类似地提供了气囊的容易和快速的放气。一个优选的实施例包括一个低容量的注射器和安装在一个壳体内的大型注射器。低体积注射器中的端口与大型注射器筒连通。低体积注射器柱塞由设置在壳体上的旋钮控制。大型注射器用于灌注外科气囊系统，包括导管，并且低体积注射器输送精确的预定体积的流体以使气囊膨胀。低体积注射器也用于使气囊放气。优选地，邻近旋钮的壳体上的标记指示旋钮的所需旋转以输送要注射的正确体积的流体以匹配给定尺寸和形状的气囊，使得气囊适当地充气。

10. 发明授权

US6022336A Catheter system for emboli containment 失效
公开(公告)号：US6022336A
公开(公告)日：2000-02-08
申请号：US812570
申请日：1997-03-06
申请人： Gholam-Reza Zadno-Azizi , Celso J. Bagaoisan , Ketan P. Muni
发明人： Gholam-Reza Zadno-Azizi , Celso J. Bagaoisan , Ketan P. Muni
IPC分类号： A61B17/22 , A61F2/958 , A61M1/00 , A61M25/00 , A61M29/02 , B29C55/04 , A61M29/00
CPC分类号： A61M25/10184 , A61B17/22 , A61M25/0009 , A61M25/0053 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/1011 , A61M25/1018 , A61M25/104 , B29C55/04 , A61B2017/22067 , A61B2017/22084 , A61B2217/005 , A61M2025/0018 , A61M2025/0037 , A61M2025/0081 , A61M2025/0183 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1031 , A61M2025/1052 , A61M2025/1079 , A61M2025/109 , A61M2025/1093 , A61M25/0026 , A61M25/0029 , A61M25/005 , A61M25/0068 , A61M25/007 , A61M25/008 , A61M25/10 , A61M25/1027
摘要： A multi-catheter emboli containment system is disclosed which is adapted to provide at least one pair of optimized paths for irrigation and aspiration fluid flow. Through careful design of the cross-sectional area of these paths, the present system is able to be compactly utilized in even the smaller size blood vessels. The catheter system itself is provided with occlusive devices to form an emboli containment chamber in which irrigation and aspiration occur. The catheter system of the present invention provides an improved emboli containment and removal system which can be utilized in a wide range of vessel diameters. The system is easy to use and can quickly and efficiently evacuate the containment chamber.

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