专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US11065349B2 18F labeled BODIPY dye and its derivatives for PET imaging of heart perfusion and others 有权
公开(公告)号：US11065349B2
公开(公告)日：2021-07-20
申请号：US14438863
申请日：2013-03-15
申请人： Peter S. Conti , Zibo Li , Shuanglong Liu , Dan Li
发明人： Peter S. Conti , Zibo Li , Shuanglong Liu , Dan Li
IPC分类号： A61K51/04 , A61K49/00 , A61B5/00 , A61B6/03
摘要： This invention provides a class of dual mode imaging tracer capable of acting both as a fluorescent imaging tracer and a positron emission tomography imaging tracer. Tracers in accordance with this invention generally have a fluorescent core with a boron-fluoride element embedded therein. Exemplary embodiments of the tracer include 18F-labeled BODIPY compounds and derivative thereof. Also provided are tracer kits containing a sterile formulation of a BODIPY dye either in a radio-labeled or pre-labeled state, and methods for imaging heart perfusion using the 18F-labeled dual mode tracers.

2. 发明授权

US09225390B2 Wireless power supplying system and adaptive adjustment method thereof 有权
标题翻译：无线供电系统及其自适应调整方法
公开(公告)号：US09225390B2
公开(公告)日：2015-12-29
申请号：US13701005
申请日：2010-12-23
申请人： Dan Li , Bing Bai , Ying Chen , Yilong Xu
发明人： Dan Li , Bing Bai , Ying Chen , Yilong Xu
IPC分类号： H01F27/42 , H04B5/00 , H02J7/02
CPC分类号： H04B5/0037 , H02J7/025 , H02J50/12 , H04B5/0093
摘要： It is disclosed a wireless power supplying system and an self adaptive adjustment method thereof. The method includes: a step for detecting an operating status of an electric power sending unit and determining, based on the detected operating status, whether the electric power transmitting unit satisfies a condition of a normal operation of the system and a step for determining, based on the above determination result, whether to adjust a master frequency of an oscillating circuit so that the master frequency of the oscillating circuit is between a resonance frequency of a transmitting coil and a resonance frequency of a receiving coil. The master frequency of the oscillating circuit is adjusted automatically, so that the master frequency is always close to the resonance frequency of the transmitting coil and that of the receiving coil, thereby maintaining stably the power output of the system.
摘要翻译：公开了一种无线供电系统及其自适应调整方法。该方法包括：用于检测电力发送单元的运行状态的步骤，并且基于检测到的运行状态来确定电力发送单元是否满足系统的正常运行的条件和基于用于确定的步骤根据上述确定结果，是否调整振荡电路的主频率使得振荡电路的主频率在发射线圈的谐振频率和接收线圈的谐振频率之间。自动调整振荡电路的主频率，使得主频率总是接近发射线圈和接收线圈的谐振频率，从而稳定地保持系统的功率输出。

3. 发明授权

US09101773B2 Cross-channel noise detector in implantable medical devices 有权
标题翻译：可植入医疗器械中的跨通道噪声检测器
公开(公告)号：US09101773B2
公开(公告)日：2015-08-11
申请号：US12693512
申请日：2010-01-26
申请人： Dan Li , David L. Perschbacher
发明人： Dan Li , David L. Perschbacher
IPC分类号： A61N1/365 , A61N1/37 , A61N1/39
CPC分类号： A61N1/3704 , A61N1/3718 , A61N1/3925
摘要： An apparatus comprises a primary cardiac signal sensing circuit to sense a first cardiac signal, a secondary cardiac signal sensing to sense a second cardiac signal, and an arrhythmia detection circuit. The primary sensing circuit includes at least first and second implantable electrodes, and the secondary sensing circuit includes a third implantable electrode to deliver high-energy shock therapy. The arrhythmia detection circuit detects tachyarrhythmia using the primary sensing circuit, determines correspondence between events sensed with the primary sensing circuit and events sensed with the secondary sensing circuit, and deems whether a detected rhythm is indicative of noise or is indicative of an arrhythmia according to the determined correspondence.
摘要翻译：一种装置包括用于感测第一心脏信号的主要心脏信号感测电路，感测第二心脏信号的次要心脏信号感测和心律失常检测电路。主感测电路至少包括第一和第二可植入电极，并且次级感测电路包括用于输送高能量休克疗法的第三可植入电极。心律失常检测电路使用主感测电路检测快速性心律失常，确定用主感测电路感测的事件与由次级感测电路感测的事件之间的对应关系，并且考虑检测到的节奏是指示噪声还是指示心律失常根据确定的信件。

4. 发明授权

US09008760B2 System and method for off-line analysis of cardiac data 有权
标题翻译：心脏数据离线分析的系统和方法
公开(公告)号：US09008760B2
公开(公告)日：2015-04-14
申请号：US13483394
申请日：2012-05-30
申请人： Yanting Dong , Shijie Zhang , Deepa Mahajan , Chenguang Liu , Dan Li , Yayun Lin , Derek D. Bohn
发明人： Yanting Dong , Shijie Zhang , Deepa Mahajan , Chenguang Liu , Dan Li , Yayun Lin , Derek D. Bohn
IPC分类号： A61B5/04 , A61B5/0452 , A61B5/00 , A61B5/0245 , A61B5/042 , A61N1/37
CPC分类号： A61B5/0452 , A61B5/0245 , A61B5/042 , A61B5/7217 , A61N1/3704
摘要： A system and method for performing off-line analysis of cardiac electrogram data, comprising: retrieving an electrogram from a memory location; identifying a first-channel group of candidate beats from at least a first channel of the electrogram; and identifying a second-channel group of candidate beats from at least a second channel of an electrogram. For each first-channel beat candidate near a second-channel beat candidate, the amplitude of the first-channel beat candidate is compared with the amplitude of a previous beat and the amplitude of a next beat on the first electrogram channel, and first-channel beat candidates that are outside of a first pre-determined range from either the previous or next beat are removed. Then first-channel beat candidates that are outside of a second pre-determined range from either the previous or next beat candidate are removed.
摘要翻译：一种用于执行心电图数据的离线分析的系统和方法，包括：从存储器位置检索电描记图; 从所述电描记图的至少第一通道识别候选节拍的第一通道组; 以及从电描记图的至少第二通道识别候选节拍的第二通道组。对于靠近第二声道拍子候选的每个第一声道拍子候选，将第一声道拍子候选的幅度与先前拍子的幅度和第一电摄影通道上的下一拍子的幅度进行比较，并且将第一声道从前一个或下一个节拍中跳出超出第一个预定范围之外的候选人被删除。然后，除去来自前一个或下一个节拍候选的第二预定范围之外的第一声道拍子候选。

5. 发明申请

US20150028681A1 MULTI-LEVEL OUTPUT CASCODE POWER STAGE 有权
标题翻译：多电平输出电源电路
公开(公告)号：US20150028681A1
公开(公告)日：2015-01-29
申请号：US14063636
申请日：2013-10-25
申请人： Dan LI
发明人： Dan LI
IPC分类号： H03K17/00
CPC分类号： H03K17/08104 , H03F1/223 , Y10T307/696
摘要： A power stage to generate an output voltage at one of a high reference voltage, an intermediate reference voltage and a low reference voltage, including a first switch stage connecting the output terminal to the high reference voltage, comprising a pair of transistors connected in series along their source-to-drain paths, a first transistor coupled to the output terminal and having its gate biased at the intermediate voltage, a second transistor having a gate that receives a first stage control signal that varies between the high reference voltage and the intermediate reference voltage, a second switch stage connecting the output terminal to the intermediate reference voltage, having a gate that receives a second stage control signal that varies among the high reference voltage, intermediate reference voltage and low reference voltage, a third switch stage connecting the output terminal to the low reference voltage, having a pair of transistors connected in series along their source-to-drain paths, a first transistor coupled to the output terminal and having its gate biased at the intermediate voltage, a second transistor having a gate that receives a third stage control signal that varies between the intermediate reference voltage and the low reference voltage.
摘要翻译：一种功率级，用于在高参考电压，中间参考电压和低参考电压之一产生输出电压，包括将输出端连接到高参考电压的第一开关级，包括串联连接的一对晶体管其源极到漏极路径，耦合到输出端并且其栅极偏置在中间电压的第一晶体管，具有栅极的第二晶体管，其接收在高参考电压和中间参考之间变化的第一级控制信号电压，将输出端子连接到中间参考电压的第二开关级，具有接收在高参考电压，中间参考电压和低参考电压之间变化的第二级控制信号的栅极;连接输出端子的第三开关级到低参考电压，具有沿其源极串联连接的一对晶体管所述第一晶体管耦合到所述输出端子并且其栅极偏置在所述中间电压，第二晶体管具有接收在所述中间参考电压和所述低参考电压之间变化的第三级控制信号的栅极。

6. 发明授权

US08909808B2 Redundancy elimination for web caching 有权
标题翻译：网络缓存的冗余消除
公开(公告)号：US08909808B2
公开(公告)日：2014-12-09
申请号：US13552696
申请日：2012-07-19
申请人： Dan Li , Mahesh Viveganandhan , Dipak Punnoran Koroth , Ming Tan , Martin Ostrowski
发明人： Dan Li , Mahesh Viveganandhan , Dipak Punnoran Koroth , Ming Tan , Martin Ostrowski
IPC分类号： G06F15/16
CPC分类号： G06F17/30902 , H04L67/02
摘要： In one embodiment, redundancy elimination for web caching may be provided. Upon receiving a request for a content object, a determination of whether the content object is cached may be made. In response to determining that the content object is not cached, the requested content object may be retrieved and, if the content object is associated with an aggregate popularity exceeding a caching threshold, the content object may be cached before providing the requested content object.
摘要翻译：在一个实施例中，可以提供用于web缓存的冗余消除。在接收到对内容对象的请求时，可以确定内容对象是否被缓存。响应于确定内容对象未被缓存，可以检索所请求的内容对象，并且如果内容对象与超过高速缓存阈值的聚合流行度相关联，则可以在提供所请求的内容对象之前高速缓存内容对象。

7. 发明授权

US08903490B2 Methods and systems for recognizing arrhythmias using neural stimulation 有权
标题翻译：使用神经刺激识别心律失常的方法和系统
公开(公告)号：US08903490B2
公开(公告)日：2014-12-02
申请号：US13019868
申请日：2011-02-02
申请人： Dan Li
发明人： Dan Li
IPC分类号： A61N1/00 , A61N1/365
CPC分类号： A61N1/365
摘要： In various method embodiments for classifying an arrhythmia, a characteristic of a ventricle is sensed before delivering a diagnostic neural stimulation. The diagnostic neural stimulation is delivered, and the characteristic of the ventricle is sensed while delivering the diagnostic neural stimulation. The sensed characteristic of the ventricle before and during the diagnostic neural stimulation is used to classify the arrhythmia as either a supraventricular tachyarrhythmia (SVT) or a ventricular tachycardia (VT). According to various embodiments, the characteristic of the ventricle is ventricular rate, similarity values of sensed ventricular morphology to a normal sinus rhythm (NSR), or ventricular hemodynamics. Various embodiments use ventricular rate regularity before and during the diagnostic neural stimulation to classify an SVT as atrial fibrillation (AF) or as another SVT.
摘要翻译：在用于分类心律失常的各种方法实施例中，在递送诊断神经刺激之前感测到心室的特征。传递诊断性神经刺激，并且在传递诊断性神经刺激时感测心室的特征。在诊断神经刺激之前和期间感测到的心室特征被用于将心律失常分为室上性快速性心律失常（SVT）或室性心动过速（VT）。根据各种实施例，心室的特征是心室率，感测的心室形态与正常窦性心律（NSR）的相似性值或心室血流动力学。各种实施例在诊断神经刺激之前和期间都使用心室率规律性将SVT分类为心房颤动（AF）或另一SVT。

8. 发明授权

US08725258B2 Method and apparatus for automated adjustment of arrhythmia detection duration 有权
标题翻译：用于自动调节心律失常检测持续时间的方法和装置
公开(公告)号：US08725258B2
公开(公告)日：2014-05-13
申请号：US11467421
申请日：2006-08-25
申请人： Dan Li , Shelley Cazares
发明人： Dan Li , Shelley Cazares
IPC分类号： A61N1/362
CPC分类号： A61N1/3624 , A61B5/046 , A61B5/0464 , A61B5/7275 , A61N1/3622 , A61N1/3925 , A61N1/3962 , A61N1/3987
摘要： A cardiac rhythm management (CRM) system delivers anti-tachyarrhythmia therapies and uses patient-specific and/or tachyarrhythmia event-specific information to automatically set and adjust one or more arrhythmia detection durations. In one embodiment, the CRM system initializes and updates the one or more arrhythmia detection durations using patient-specific information such as medical history and recent medical trends. In another embodiment, the CRM dynamically adjusts the one or more arrhythmia detection durations using the patient's hemodynamic performance. One example of such an arrhythmia detection duration is a sustained rate duration (SRD) that starts when a tachyarrhythmia such as a supraventricular tachyarrhythmia is detected. An anti-tachyarrhythmia therapy is delivered only if the tachyarrhythmia sustains throughout the SRD.
摘要翻译：心律管理（CRM）系统提供抗心律失常疗法，并使用患者特异性和/或快速性心律失常事件特定信息来自动设置和调整一种或多种心律失常检测持续时间。在一个实施例中，CRM系统使用患者特定信息（例如病史和最近的医疗趋势）来初始化和更新一个或多个心律失常检测持续时间。在另一个实施例中，CRM使用患者的血液动力学性能来动态地调整一个或多个心律失常检测持续时间。这种心律失常检测持续时间的一个例子是当检测到诸如室上性快速性心律失常之类的快速性心律失常时开始的持续速率持续时间（SRD）。仅在快速性心律失常在整个SRD中持续时才能进行抗快速性心律失常治疗。

9. 发明授权

US08715610B2 Process for the preparation of graphene 有权
标题翻译：制备石墨烯的方法
公开(公告)号：US08715610B2
公开(公告)日：2014-05-06
申请号：US12738758
申请日：2008-10-17
申请人： Gordon George Wallace , Dan Li
发明人： Gordon George Wallace , Dan Li
IPC分类号： C01B31/04 , C09C1/56
CPC分类号： B82Y40/00 , B82Y30/00 , C01B32/15 , C01P2002/72 , C01P2002/84 , C01P2002/88 , C01P2004/03 , C01P2004/24 , H01B1/24
摘要： The present invention relates to a process for the preparation of graphene which can be used in the development of graphene paper or films, graphene-based composites and articles for nanoelectronics, nanocomposites, batteries, supercapacitors, hydrogen storage and bioapplications. This process comprises reducing purified exfoliated graphite oxide in the presence of a base.
摘要翻译：本发明涉及可用于石墨烯纸或薄膜，石墨烯基复合材料和用于纳米电子学，纳米复合材料，电池，超级电容器，储氢和生物应用的制品的开发中的石墨烯的制备方法。该方法包括在碱的存在下还原纯化的剥离的氧化石墨。

10. 发明授权

US08694129B2 Deployable sensor platform on the lead system of an implantable device 有权
标题翻译：可植入装置引导系统上的可部署传感器平台
公开(公告)号：US08694129B2
公开(公告)日：2014-04-08
申请号：US12686050
申请日：2010-01-12
申请人： Dan Li , Allan C. Shuros , Andrea Acuna , Bruce A. Tockman
发明人： Dan Li , Allan C. Shuros , Andrea Acuna , Bruce A. Tockman
IPC分类号： A61B5/02
CPC分类号： A61N1/056 , A61B5/042 , A61B5/6846 , A61B5/6852 , A61M25/0082 , A61M25/01 , A61M25/0102 , A61M25/0662 , A61M2025/0681 , A61N1/37211 , A61N2001/0585
摘要： Systems and methods for deploying a sensor assembly onto a cardiac lead are disclosed. The sensor assembly can include a resilient cuff having one or more sensor modules for sensing physiological parameters within the body. The resilient cuff may have a substantially cylindrical shape having an inner diameter that is smaller than an outer diameter of the lead body onto which the cuff is deployed such that the cuff is retained on the lead body by frictional forces. The sensor assembly may be deployed in conjunction with a new lead to be implanted within a chamber of the patient's heart or a body vessel, or may be deployed onto an existing, implanted lead implanted within the patient's body.
摘要翻译：公开了将传感器组件部署到心脏引线上的系统和方法。传感器组件可以包括具有用于感测身体内的生理参数的一个或多个传感器模块的弹性袖带。弹性箍可以具有基本上圆柱形的形状，其内径小于引导体的外径，袖带在其上展开，使得袖带通过摩擦力保持在引线体上。传感器组件可以与将要植入患者心脏或身体容器的腔室内的新导线一起部署，或者可以部署到植入患者体内的现有植入的导线上。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式