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1. 发明授权

US10542222B2 Multiview body camera system with environmental sensors and alert features 有权
公开(公告)号：US10542222B2
公开(公告)日：2020-01-21
申请号：US16223703
申请日：2018-12-18
申请人： Daniel Arnold
发明人： Daniel Arnold
IPC分类号： H04N5/00 , A41D1/00 , H04N5/247 , A41D1/04 , G02B27/01 , H04N5/225 , A42B3/04
摘要： A multiview body camera system with a vest, a helmet, shoulder pads, camera units providing video, directional microphones providing audio, sensors providing motion detection and other functions is described herein. A control module controls camera units, microphones, sensors and all other circuitry. A tamper-proof locking compartment containing elements of the body camera system is operable by a remote control signal transmitted from an authorized party or by a security code. The body camera system features voice command recognition, real time monitoring, recording, storing, remote reporting; alerts the wearer of impending threats, such as approaching cars, persons, objects or gunshots and may incorporate a visor that provides a panoramic view. The body camera integrates all components internally. Bullet resistant material is used in the construction of the vest and helmet. The device operates continuously, and the wearer cannot disrupt the operation without consequence. All recorded data is archived an internal memory.

2. 发明申请

US20120312639A1 FLOOR POSITION DETECTION DEVICE 有权
标题翻译：地板位置检测装置
公开(公告)号：US20120312639A1
公开(公告)日：2012-12-13
申请号：US13518074
申请日：2010-12-01
申请人： Daniel Arnold , Eric Birrer
发明人： Daniel Arnold , Eric Birrer
IPC分类号： B66B3/02
CPC分类号： B66B1/50 , B66B1/3492
摘要： A floor position detection device of an elevator system includes a first sensor unit having a first Hall sensor and which is provided to detect at least one floor position characteristic, and an evaluation unit which is provided to evaluate the floor position characteristic for generating a floor signal. The sensor unit includes a second Hall sensor and the evaluation unit evaluates at least two floor position characteristics for generating the floor signal.
摘要翻译：电梯系统的楼层位置检测装置包括具有第一霍尔传感器的第一传感器单元，其被设置用于检测至少一个楼层位置特性;以及评估单元，其被提供以评估用于产生楼层信号的楼层位置特性。传感器单元包括第二霍尔传感器，并且评估单元评估至少两个楼层位置特性以产生楼层信号。

3. 发明授权

US07368264B2 SLC1A1 marker for anxiety disorder 有权
标题翻译： SLC1A1焦虑症标志物
公开(公告)号：US07368264B2
公开(公告)日：2008-05-06
申请号：US11591244
申请日：2006-10-31
申请人： Paul Daniel Arnold , Margaret A. Richter , James Lowery Kennedy
发明人： Paul Daniel Arnold , Margaret A. Richter , James Lowery Kennedy
IPC分类号： C12P19/34
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： The present invention provides methods for diagnosing or identifying susceptibility of a subject to an anxiety or mood disorder. One method involves testing a sample obtained from the subject for the presence of a polymorphism in Intron 10 of the SLC1A1 gene. The presence of allele G or allele A of the A/G polymorphism rs301434 indicates that the patient is susceptible to an anxiety disorder. An alternate method involves testing a sample obtained from the subject for the presence of a polymorphism in the 3′ untranslated region of the SLC1A1 gene. The presence of allele C of C/G polymorphism rs3087879 indicates that the patient is susceptible to an anxiety disorder. Furthermore, a method is provided that involves testing a sample obtained from the subject for the presence of a haplotype in the SLC1A1 gene, wherein the combined presence allele G of the A/G polymorphism rs301434 and allele C of C/G polymorphism rs3087879 indicates that the patient is susceptible to a mood disorder.
摘要翻译：本发明提供用于诊断或鉴定受试者对焦虑或情绪障碍的易感性的方法。一种方法包括测试从受试者获得的样品在SLC1A1基因的内含子10中存在多态性。 A / G多态性rs301434等位基因G或等位基因A的存在表明患者易患焦虑症。一种替代方法包括测试从受试者获得的样品在SLC1A1基因的3'非翻译区中存在多态性。 C / G多态性rs3087879等位基因C的存在表明患者易患焦虑症。此外，提供了一种方法，其包括测试从受试者获得的样品中SLC1A1基因中单体型的存在，其中A / G多态性rs301434的组合存在等位基因G和C / G多态性rs3087879的等位基因C表明患者容易发生心境障碍。

4. 发明授权

US5747498A Alkynyl and azido-substituted 4-anilinoquinazolines 失效
标题翻译：炔基和叠氮取代的4-苯胺基喹唑啉
公开(公告)号：US5747498A
公开(公告)日：1998-05-05
申请号：US653786
申请日：1996-05-28
申请人： Rodney Caughren Schnur , Lee Daniel Arnold
发明人： Rodney Caughren Schnur , Lee Daniel Arnold
IPC分类号： C07D239/94 , C07D401/12 , C07D403/12 , C07D491/04 , C07D521/00 , A61K31/495 , A61K31/505 , C07D239/70
CPC分类号： C07D231/12 , C07D233/56 , C07D239/94 , C07D249/08 , C07D401/12 , C07D403/12 , C07D491/04
摘要： The invention relates to compounds of the formula ##STR1## and to pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, n and m are as defined herein. The compounds of formula I are useful in the treatment of hyperproliferative diseases, such as cancer. The invention further relates to processes of making the compounds of formula I and to methods of using such compounds in the treatment of hyperproliferative diseases.
摘要翻译：本发明涉及式Ⅰ化合物及其药学上可接受的盐，其中R 1，R 2，R 3，R 4，n和m如本文所定义。式I化合物可用于治疗过度增生性疾病，如癌症。本发明还涉及制备式I化合物的方法和使用这些化合物治疗过度增殖性疾病的方法。

5. 发明申请

US20180249087A1 MULTIVIEW BODY CAMERA SYSTEM WITH ENVIRONMENTAL SENSORS AND ALERT FEATURES 审中-公开
公开(公告)号：US20180249087A1
公开(公告)日：2018-08-30
申请号：US15756437
申请日：2016-08-31
申请人： Daniel Arnold
发明人： Daniel Arnold
IPC分类号： H04N5/247 , H04R1/02 , G10L15/22 , H04R1/40 , H04N5/225 , H04N5/232 , A41D1/00 , A41D1/04 , A41D13/005 , A41D27/26 , A42B3/04 , A42B3/30 , A42B3/22 , A41D27/20 , F41H1/02 , F41H1/04 , G02B27/01
CPC分类号： H04N5/247 , A41D1/002 , A41D1/04 , A41D13/0051 , A41D27/205 , A41D27/26 , A42B3/042 , A42B3/046 , A42B3/22 , A42B3/30 , F41H1/02 , F41H1/04 , G02B27/017 , G02B27/0172 , G02B27/0176 , G02B2027/0138 , G02B2027/0141 , G02B2027/0156 , G06F3/16 , G10L15/22 , G10L2015/223 , H04N5/2253 , H04N5/23238 , H04N5/77 , H04N9/806 , H04R1/028 , H04R1/406
摘要： A multiview body camera system comprising a vest, a helmet, shoulder pads, camera units providing video, directional microphones providing audio, sensors providing motion detection and other functions is described herein. A control module controls camera units, microphones, sensors and all other circuitry. A tamper-proof locking compartment containing elements of the body camera system is operable by a remote control signal transmitted from an authorized party or by a security code. The body camera system features voice command recognition, real time monitoring, recording, storing, remote reporting; alerts the wearer of impending threats, such as approaching cars, persons, objects or gunshots and may incorporate a visor that provides a panoramic view. The body camera integrates all components internally. Bullet resistant material is used in the construction of the vest and helmet. The device operates continuously, and the wearer cannot disrupt the operation without consequence. All recorded data is archived an internal memory.

6. 发明申请

US20140296181A1 METHODS OF MODULATING ONCOGENIC FUSION PROTEINS 审中-公开
标题翻译：调节基因融合蛋白的方法
公开(公告)号：US20140296181A1
公开(公告)日：2014-10-02
申请号：US14110293
申请日：2012-04-09
申请人： Lee Daniel Arnold , Kenneth W. Foreman
发明人： Lee Daniel Arnold , Kenneth W. Foreman
IPC分类号： C07F5/02 , C07F7/02
CPC分类号： C07F5/025 , C07F7/02 , C07K14/82 , C07K2319/00 , C07K2319/70 , C07K2319/71 , C07K2319/80 , C07K2319/90
摘要： Described herein, at least in part, are methods of modulating oncogenic fusion proteins.
摘要翻译：本文描述至少部分是调节致癌融合蛋白的方法。

7. 发明授权

US08849991B2 System and method for hypertext transfer protocol layered reconstruction 有权
标题翻译：超文本传输协议分层重构的系统与方法
公开(公告)号：US08849991B2
公开(公告)日：2014-09-30
申请号：US12968453
申请日：2010-12-15
申请人： Joseph H. Levy , Matthew Scott Wood , Daniel Arnold , Kenny Foisy , Dave Tubbs
发明人： Joseph H. Levy , Matthew Scott Wood , Daniel Arnold , Kenny Foisy , Dave Tubbs
IPC分类号： G06F15/173 , H04L12/26 , G06F17/30
CPC分类号： G06F17/30902 , H04L43/18
摘要： HTTP layered reconstruction is disclosed. A database is queried to identify a location of a previously reconstructed HTML artifact file or packet data of a HTML file in a repository that stores packet data captured from a network. The reconstructed HTML file is analyzed. Links to external files are identified and the database is queried to identify a location of previously reconstructed artifact files or packet data of associated external files. The external files are reconstructed, as needed. A web page is then reconstructed based on the reconstructed HTML file and reconstructed external files, presenting a view of the web page as it originally appeared to a user. A user may specify which external file types to include and/or not include. New versions of external files may be obtained and indicated in the reconstructed web page when associated artifact files or packet data are not stored within the repository.
摘要翻译：公开了HTTP分层重建。查询数据库以识别存储从网络捕获的分组数据的存储库中的先前重建的HTML工件文件或HTML文件的分组数据的位置。分析重建的HTML文件。识别与外部文件的链接，并查询数据库以识别先前重建的工件文件或相关外部文件的数据包数据的位置。根据需要重构外部文件。然后基于重构的HTML文件和重建的外部文件来重构网页，呈现网页最初对用户看来的视图。用户可以指定要包括和/或不包括的外部文件类型。当相关联的工件文件或分组数据不存储在存储库中时，可以在重建的网页中获得并指示新版本的外部文件。

8. 发明申请

US20140194383A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME 审中-公开
标题翻译：可以在水溶液中二维分离的单体及其使用方法
公开(公告)号：US20140194383A1
公开(公告)日：2014-07-10
申请号：US14110056
申请日：2012-04-09
申请人： Francis Barany , Maneesh Pingle , Donald E. Bergstrom , Sarah F. Giardina , Lee Daniel Arnold
发明人： Francis Barany , Maneesh Pingle , Donald E. Bergstrom , Sarah F. Giardina , Lee Daniel Arnold
IPC分类号： C07D211/26 , C07F5/04
CPC分类号： C07D211/26 , C07D405/06 , C07D409/06 , C07D491/107 , C07F5/025 , C07F5/04
摘要： Described herein are monomers capable of forming a biologically useful multimer when in contact with one, two, three or more other monomers in an aqueous media. In one aspect, such monomers may be capable of binding to another monomer in an aqueous media (e.g. in vivo) to form a multimer, (e.g. a dimer). Contemplated monomers may include a ligand moiety, a linker element, and a connector element that joins the ligand moiety and the linker element. In an aqueous media, such contemplated monomers may join together via each linker element and may thus be capable of modulating one or more biomolecules substantially simultaneously, e.g., modulate two or more binding domains on a protein or on different proteins.
摘要翻译：本文描述的是当在水性介质中与一种，两种，三种或更多种其它单体接触时，能够形成生物有用的多聚体的单体。在一个方面，这样的单体可以能够在水性介质（例如体内）中结合另一单体以形成多聚体（例如二聚体）。考虑的单体可以包括配体部分，连接体元件和连接配体部分和连接体元件的连接器元件。在水性介质中，这样预期的单体可以经由每个连接体元件连接在一起，因此可以基本上同时调节一种或多种生物分子，例如调节蛋白质上或不同蛋白质上的两个或多个结合结构域。

9. 发明申请

US20140163229A1 SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME 审中-公开
标题翻译：可在水溶液中多元化的SILYL单体及其使用方法
公开(公告)号：US20140163229A1
公开(公告)日：2014-06-12
申请号：US14110060
申请日：2012-04-09
申请人： Francis Barany , Maneesh Pingle , Donald E. Bergstrom , Sarah F. Giardina , Lee Daniel Arnold
发明人： Francis Barany , Maneesh Pingle , Donald E. Bergstrom , Sarah F. Giardina , Lee Daniel Arnold
IPC分类号： C07F7/10
CPC分类号： A61K31/695 , A61K47/55 , C07F7/10
摘要： Described herein are silyl monomers capable of forming a biologically useful multimer when in contact with one, two, three or more other monomers in an aqueous media. Such multimer forming associations of monomers may be promoted by the proximal binding of the monomers to their target biomolecule(s). In one aspect, such monomers may be capable of binding to another monomer in an aqueous media (e.g. in vivo) to form a multimer, (e.g. a dimer). Contemplated monomers may include a ligand moiety, a linker element, and a connector element that joins the ligand moiety and the linker element. In an aqueous media, such contemplated monomers may join together via each linker element and may thus be capable of modulating one or more biomolecules substantially simultaneously, e.g., modulate two or more binding domains on a protein or on different proteins.
摘要翻译：本文描述的是当在水性介质中与一种，两种，三种或更多种其它单体接触时能够形成生物学上有用的多聚体的甲硅烷基单体。单体的这种多聚体形成关联可以通过单体与其目标生物分子的近端结合来促进。在一个方面，这样的单体可以能够在水性介质（例如体内）中结合另一单体以形成多聚体（例如二聚体）。考虑的单体可以包括配体部分，连接体元件和连接配体部分和连接体元件的连接器元件。在水性介质中，这样预期的单体可以经由每个连接体元件连接在一起，因此可以基本上同时调节一种或多种生物分子，例如调节蛋白质上或不同蛋白质上的两个或多个结合结构域。

10. 发明授权

US08464841B2 Method and apparatus for determining the movement and/or the position of an elevator car 有权
标题翻译：用于确定电梯轿厢的运动和/或位置的方法和装置
公开(公告)号：US08464841B2
公开(公告)日：2013-06-18
申请号：US12976051
申请日：2010-12-22
申请人： Eric Birrer , Daniel Arnold
发明人： Eric Birrer , Daniel Arnold
IPC分类号： B66B1/34
CPC分类号： B66B5/06 , B66B1/3492
摘要： A method and apparatus for determining the movement and/or the position of an elevator car include a first monitoring unit for analyzing first signals of a first sensor device for obtaining information about the movement and/or the position of the elevator car, for detecting a possible faulty behavior of the elevator system, and for initiating corresponding safety measures. A second sensor device, which does not operate on the principle of the first sensor device, registers changes of the movement state of the elevator car and emits corresponding second signals to a second monitoring unit that analyzes the second signals and detects changes of the movement state of the elevator car. A fault signal is generated if the movement signals that are obtained from the first monitoring unit are incoherent with the changes of the movement state of the elevator car that are detected by the second monitoring unit.
摘要翻译：用于确定电梯轿厢的运动和/或位置的方法和装置包括：第一监测单元，用于分析第一传感器装置的第一信号，以获得关于电梯轿厢的运动和/或位置的信息，电梯系统的可能的故障行为，以及启动相应的安全措施。不按照第一传感器装置的原理运行的第二传感器装置记录电梯轿厢的运动状态的变化并将相应的第二信号发射到分析第二信号并检测运动状态的变化的第二监视单元的电梯车。如果从第一监视单元获得的移动信号与由第二监视单元检测到的电梯轿厢的移动状态的变化不一致，则产生故障信号。

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