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1. 发明授权

US09838802B1 Underwater acoustic carbon nanotube thermophone 有权
公开(公告)号：US09838802B1
公开(公告)日：2017-12-05
申请号：US15273801
申请日：2016-09-23
申请人： Thomas R Howarth , Dehua Huang
发明人： Thomas R Howarth , Dehua Huang
IPC分类号： H04R23/00 , G01S7/521
CPC分类号： H04R23/002 , G01S7/521 , H04R1/44 , H04R2201/028 , H04R2307/023
摘要： A carbon nanotube thermophone is provided which includes a urethane frame having mounting holes at corners of the frame. Screw holes in the frame are provided for a cable holder. A square shaped carbon nanotube material chip is positioned within the urethane frame. The carbon nanotube material chip can comprise multiple carbon nanotube sheets to electrically tune the impedance to match a driving amplifier impedance load. Wooden spacers assist in positioning the carbon nanotube material chip. A first end of a cable is soldered to the carbon nanotube material chip at electrodes of the material chip. A high temperature rated silicon sealant is used for attachment points on the thermophone.

2. 发明授权

US09781520B1 Passive mode carbon nanotube underwater acoustic transducer 有权
公开(公告)号：US09781520B1
公开(公告)日：2017-10-03
申请号：US15270166
申请日：2016-09-20
申请人： Dehua Huang
发明人： Dehua Huang
IPC分类号： H04R23/00 , H04R1/44 , B82Y15/00
CPC分类号： H04R23/002 , B82Y15/00 , H04R1/44 , H04R2307/023
摘要： A passive carbon nanotube transducer is provided. The passive carbon nanotube transducer includes shells as protective walls for the top and bottom housing of the transducer with carbon nanotube sheets affixed between the shells. The shells act as acoustic windows that match the surrounding acoustic medium. A gasket encloses the shells and carbon nanotube sheets of the transducer. Each carbon nanotube sheet has an electrode at both ends. Multiple carbon nanotube sheets are capable of sensing sound induced environment temperature deviations and converting electric voltage or current for passive acoustic detection.

3. 发明授权

US08788823B1 System and method for filtering network traffic 有权
标题翻译：过滤网络流量的系统和方法
公开(公告)号：US08788823B1
公开(公告)日：2014-07-22
申请号：US10971523
申请日：2004-10-22
申请人： Dehua Huang , Adam J. Sweeney , Pradeep S. Sudame , Silviu Dobrota , Premkumar Jonnala
发明人： Dehua Huang , Adam J. Sweeney , Pradeep S. Sudame , Silviu Dobrota , Premkumar Jonnala
IPC分类号： H04L9/32
CPC分类号： H04L63/10 , H04L63/0263
摘要： Protocol status information is used to perform traffic filtering by dropping messages that are not consistent with the protocol status information. In one embodiment, a method involves comparing message information and protocol status information. The message information is associated with a first message. The protocol status information is obtained in response to one or more second messages, which are conveyed according to a protocol used to assign network addresses to clients. The method also involves determining whether to discard the first message, based on an outcome of the comparison of the message information and the protocol status information. For example, it can be determined that the first message should be discarded, if the message information does not match the protocol status information.
摘要翻译：协议状态信息用于通过丢弃与协议状态信息不一致的消息来进行流量过滤。在一个实施例中，一种方法包括比较消息信息和协议状态信息。消息信息与第一消息相关联。响应于根据用于向客户端分配网络地址的协议传送的一个或多个第二消息来获得协议状态信息。该方法还包括基于消息信息和协议状态信息的比较的结果来确定是否丢弃第一消息。例如，如果消息信息与协议状态信息不匹配，则可以确定第一消息应被丢弃。

4. 发明授权

US08526270B1 Acoustic multifunctional standard calibration method 失效
标题翻译：声学多功能标准校准方法
公开(公告)号：US08526270B1
公开(公告)日：2013-09-03
申请号：US13228643
申请日：2011-09-09
申请人： Dehua Huang , Scott K. Mayer
发明人： Dehua Huang , Scott K. Mayer
IPC分类号： H04B1/02 , H04B17/00 , G01S3/80
CPC分类号： G01S7/52004 , G01S3/82
摘要： A method for using a deployable, small package acoustic transmitter device is taught, which serves as a standard acoustic source for on-vessel, in-mission field calibration purposes. The method involves deploying an acoustic transmitter device underwater to provide a predefined acoustic energy source for sonar array detection as well as periodic time-coded acoustic signal pulses for tracking and calibration of passive ranging.
摘要翻译：教导了一种使用可部署的小型封装声发射器装置的方法，该装置用作用于船上任务现场校准目的的标准声源。该方法涉及在水下部署声发射器装置以提供用于声纳阵列检测的预定声能源，以及用于跟踪和校准被动测距的周期性时间编码声信号脉冲。

5. 发明申请

US20110230526A1 Thiazolyl Mglur5 Antagonists and Methods for Their Use 有权
标题翻译：噻唑基Mglur5拮抗剂及其使用方法
公开(公告)号：US20110230526A1
公开(公告)日：2011-09-22
申请号：US13016304
申请日：2011-01-28
申请人： Nicholas D. Cosford , Thomas J. Seiders , Joseph E. Payne , Jeffrey R. Roppe , Dehua Huang , Nicholas D. Smith , Steve F. Poon , Chris King , Brian W. Eastman , Bowei Wang , Jeannie M. Arruda , Jean-Michel Vernier , Xiumin Zhao
发明人： Nicholas D. Cosford , Thomas J. Seiders , Joseph E. Payne , Jeffrey R. Roppe , Dehua Huang , Nicholas D. Smith , Steve F. Poon , Chris King , Brian W. Eastman , Bowei Wang , Jeannie M. Arruda , Jean-Michel Vernier , Xiumin Zhao
IPC分类号： A61K31/4439 , A61P25/00 , A61P25/22 , A61P25/24 , A61P25/28
CPC分类号： C07D417/06 , C07D417/14 , C07D471/04
摘要： The identification of a unique series of compounds which possesses special advantages in terms of drug-like properties due to their possessing advantageous properties in terms of potency and/or pharmacokinetic and/or selectivity and/or in vivo receptor occupancy properties. Specifically, the selection of a 1,3-thiazol-2-yl ring member linked by an ethynylene to the 3 position of a pyridyl ring or the 5 position of a pyrimidinyl ring, wherein the ring is substituted with selected substituents, results in a compound having superior drug-like properties. The invention includes pharmaceutically acceptable salt forms of these heterocyclic compounds, in particular chloride salts and trifluoroacetate salts.
摘要翻译：由于它们在效力和/或药代动力学和/或选择性和/或体内受体占有性方面具有有利的性质，鉴定了具有药物性质特征的独特系列化合物。具体地说，通过亚乙炔基连接到吡啶环的3位或嘧啶环的5位上的1,3-噻唑-2-基环成员的选择，其中环被选定的取代基取代，得到具有优异药物性质的化合物。本发明包括这些杂环化合物的药学上可接受的盐形式，特别是氯化物盐和三氟乙酸盐。

6. 发明授权

US07981893B2 Heteroaryl compounds, compositions thereof, and methods of treatment therewith 有权
标题翻译：杂芳基化合物，其组合物及其处理方法
公开(公告)号：US07981893B2
公开(公告)日：2011-07-19
申请号：US11975652
申请日：2007-10-18
申请人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Branden G. Lee , Roy Leonard Harris, III , Graziella Isabel Shevlin , Dehua Huang , Kimberly Lyn Schwarz , Garrick K. Packard , Jason Simon Parnes , Patrick William Papa , Lida Radnia Tehrani , Sophie Perrin-Ninkovic , Jennifer R. Riggs
发明人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Branden G. Lee , Roy Leonard Harris, III , Graziella Isabel Shevlin , Dehua Huang , Kimberly Lyn Schwarz , Garrick K. Packard , Jason Simon Parnes , Patrick William Papa , Lida Radnia Tehrani , Sophie Perrin-Ninkovic , Jennifer R. Riggs
IPC分类号： A61K31/4985
CPC分类号： C07D471/04 , C07D487/04 , C07D498/04
摘要： Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
摘要翻译：本文提供具有以下结构的杂芳基化合物：其中R1，R2，L，X，Y，Z，Q，A和B如本文所定义，包含有效量的杂芳基化合物的组合物和治疗或预防癌症的方法，炎性病症，免疫学条件，代谢条件和通过抑制激酶途径可治疗或可预防的病症，包括向有需要的患者施用有效量的杂芳基化合物。

7. 发明申请

US20100121944A1 DHCP PROXY FOR STATIC HOST 有权
标题翻译：用于静态主机的DHCP代理
公开(公告)号：US20100121944A1
公开(公告)日：2010-05-13
申请号：US12267774
申请日：2008-11-10
申请人： DEHUA HUANG , Premkumar Jonnala , Nagarani Chandika , Kyle Gordon Haight , Feng Zhu , Dan Mihai Florea , Bimohit Bawa
发明人： DEHUA HUANG , Premkumar Jonnala , Nagarani Chandika , Kyle Gordon Haight , Feng Zhu , Dan Mihai Florea , Bimohit Bawa
IPC分类号： G06F15/177
CPC分类号： H04L63/101 , H04L61/2015
摘要： A DHCP proxy agent is provided to send on behalf of a static host a DHCP request so that an access layer security feature such as DHCP snooping/IPSG can be applied to the static host and/or in a mixed static IP and DHCP environment.
摘要翻译：提供DHCP代理，代表静态主机发送DHCP请求，以便将访问层安全功能（如DHCP Snooping / IPSG）应用于静态主机和/或混合静态IP和DHCP环境。

8. 发明授权

US07569592B2 Heteroaryl substituted pyrazole modulators of metabotropic glutamate receptor-5 有权
标题翻译：代谢型谷氨酸受体-5的杂芳基取代的吡唑调节剂
公开(公告)号：US07569592B2
公开(公告)日：2009-08-04
申请号：US10497122
申请日：2002-12-13
申请人： Nicholas D. P. Cosford , Chixu Chen , Brian W. Eastman , Dehua Huang , Benito Munoz , Petpiboon Prasit , Nicholas D. Smith
发明人： Nicholas D. P. Cosford , Chixu Chen , Brian W. Eastman , Dehua Huang , Benito Munoz , Petpiboon Prasit , Nicholas D. Smith
IPC分类号： A61K31/4439 , A61K31/4155 , C07D401/04
CPC分类号： C07D231/38 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： Pyrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorder and panic, as well as in the treatment of pain, circadian rhythm disorders, and other diseases.
摘要翻译：直接或通过桥连与杂芳基相连接的杂芳基部分的吡唑化合物是可用于治疗精神病和情绪障碍（例如精神分裂症，焦虑症，抑郁症）的mGluR5调节剂，双相情感障碍和恐慌，以及治疗疼痛，昼夜节律紊乱和其他疾病。

9. 发明授权

US07551559B1 System and method for performing security actions for inter-layer binding protocol traffic 有权
标题翻译：为层间绑定协议流量执行安全动作的系统和方法
公开(公告)号：US07551559B1
公开(公告)日：2009-06-23
申请号：US10971521
申请日：2004-10-22
申请人： Premkumar Jonnala , Adam J. Sweeney , Dehua Huang , Silviu Dobrota , Pradeep S. Sudame , Marco E. Foschiano
发明人： Premkumar Jonnala , Adam J. Sweeney , Dehua Huang , Silviu Dobrota , Pradeep S. Sudame , Marco E. Foschiano
IPC分类号： H04L5/12
CPC分类号： H04L63/1466 , H04L63/1416
摘要： Users are allowed to specify per-interface rate limits for inter-layer binding protocol traffic. If the user-specified rate limit is exceeded on a given interface, inter-layer binding protocol messages received via that interface are caused to be dropped (e.g., by selectively dropping ILBP messages, or by simply shutting down the interface). If the rate is not exceeded, inter-layer binding protocol messages received via that interface can be validated (e.g., by comparing an inter-layer binding included in the body of an inter-layer binding protocol message to protocol status information obtained by snooping protocol messages). If the inter-layer binding does not match the protocol status information, the inter-layer binding protocol message is dropped. If a match is found, the inter-layer binding protocol message is allowed to be forwarded normally. Such systems and methods may be used to inhibit various undesirable network behavior, such as man-in-the-middle attacks.
摘要翻译：允许用户为层间绑定协议流量指定每接口速率限制。如果在给定接口上超过用户指定的速率限制，则会导致通过该接口接收到的层间绑定协议消息（例如，通过选择性地删除ILBP消息，或简单地关闭接口）。如果不超过该速率，则可以验证通过该接口接收的层间绑定协议消息（例如，通过将层间绑定协议消息正文中包含的层间绑定与通过侦听协议获得的协议状态信息进行比较消息）。如果层间绑定与协议状态信息不符，则删除层间绑定协议消息。如果发现匹配，则允许层间绑定协议消息正常转发。这样的系统和方法可以用于抑制各种不期望的网络行为，例如中间人攻击。

10. 发明授权

US07393959B2 Di-aryl substituted pyrrole modulators of metabotropic glutamate receptor-5 失效
标题翻译：代谢型谷氨酸受体-5的二芳基取代吡咯调节剂
公开(公告)号：US07393959B2
公开(公告)日：2008-07-01
申请号：US10551574
申请日：2004-03-31
申请人： Nicholas D. P. Cosford , Dehua Huang , Jeffrey R. Roppe , Nicholas D. Smith , Lida R. Tehrani
发明人： Nicholas D. P. Cosford , Dehua Huang , Jeffrey R. Roppe , Nicholas D. Smith , Lida R. Tehrani
IPC分类号： C07D401/14 , A61K31/4418 , A61K31/4439
CPC分类号： A61K31/4439 , A61K31/444 , A61K31/485 , A61K31/551 , A61K33/00 , A61K45/06 , C07D401/04 , C07D401/14 , C07D417/04 , C07D417/14 , A61K2300/00
摘要： Pyrrole compounds of Formula (I): and pharmaceutically acceptable salts thereof (where A, B, R11, R12, R13, W, X, Y and Z are as defined herein), which are substituted directly, or by a bridge, with i) a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl and ii) another heteroaryl or aryl ring, with at least one of the rings being further substituted with another ring, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, panic, and bipolar disorder, as well as in the treatment of pain, Parkinson's disease, cognitive dysfunction, epilepsy, circadian rhythm disorders, drug addiction, drug abuse, drug withdrawal, obesity and other diseases
摘要翻译：式（I）的吡咯化合物及其药学上可接受的盐（其中A，B，R 11，R 12，R 13，W ，X，Y和Z如本文所定义），其直接取代或通过桥连，其中i）杂芳基部分，其含有与杂芳基的连接点相邻的N，和ii）另一个杂芳基或芳基环，至少一个被另一个环进一步取代的环是用于治疗精神病和情绪障碍例如精神分裂症，焦虑，抑郁，恐慌和双相情感障碍以及治疗疼痛的mGluR5调节剂，帕金森病，认知功能障碍，癫痫，昼夜节律紊乱，药物成瘾，药物滥用，戒毒，肥胖等疾病

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