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1. 发明授权

US08831914B2 Pseudo-physical modeling of drawbead in stamping simulations 有权
标题翻译：在冲压模拟中的拉伸珠的伪物理建模
公开(公告)号：US08831914B2
公开(公告)日：2014-09-09
申请号：US13439267
申请日：2012-04-04
申请人： Yinong Shen , Feng Ren , Zhiyong Cedric Xia
发明人： Yinong Shen , Feng Ren , Zhiyong Cedric Xia
IPC分类号： G06F17/50 , B21D22/00
CPC分类号： G06F17/5018 , B21D22/00 , G06F17/5009 , G06F17/5086 , G06F2217/42
摘要： The stamping of a metal sheet within a stamping die is simulated. The die includes a drawbead running perpendicular to a draw direction. A plurality of successive states are generated for iteratively representing the metal sheet from a blank shape to a final stamped shape. The drawbead is represented as a two-dimensional flat band within a model of the stamping die. Forces acting on the metal sheet are calculated at each successive state to define a next successive state. The calculating step includes a restraining force of the drawbead acting on the metal sheet calculated in response to a predetermined function of a length of the metal sheet engaged in the flat band in respective states. The particular width and location of the flat band achieve improved accuracy of estimating the restraining force.
摘要翻译：模拟冲压模具内金属片的冲压。模具包括垂直于拉伸方向延伸的拉丝珠。生成多个连续状态用于从空白形状到最终冲压形状迭代地表示金属片。拉丝珠在冲压模具的模型内被表示为二维平带。在每个连续状态下计算作用在金属片上的力，以定义下一个连续状态。计算步骤包括响应于在各自状态下接合在平带中的金属片的长度的预定函数计算的作用在金属片上的拉带的约束力。扁平带的特定宽度和位置实现了估计约束力的提高的精度。

2. 发明申请

US20120283297A1 OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS 审中-公开
标题翻译：用作磷酸1-磷酸酯1（S1P1）受体激动剂的奥扎唑唑取代的吲哚衍生物
公开(公告)号：US20120283297A1
公开(公告)日：2012-11-08
申请号：US13516908
申请日：2010-12-16
申请人： James Bailey , Nigel Paul King , Xichen Lin , Feng Ren , Kheng-Chuan Tan , Sing Yeung Mak
发明人： James Bailey , Nigel Paul King , Xichen Lin , Feng Ren , Kheng-Chuan Tan , Sing Yeung Mak
IPC分类号： A61K31/4245 , C07D413/14 , C07D413/10 , A61P25/00 , A61P29/00 , A61P11/06 , A61P19/02 , A61P1/00 , A61P1/04 , A61P17/06 , A61P35/00 , A61P35/04 , A61P31/12 , A61P3/10 , A61K31/4439
CPC分类号： C07D413/04 , C07D413/14
摘要： Oxadiazole substituted indazole derivatives of formula (I) or pharmaceutical salts thereof having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their uses in the treatment of various disorders mediated by S1P1 receptors are disclosed.
摘要翻译：公开了式（I）的恶二唑取代的吲唑衍生物或其药理学活性的药物盐，其制备方法，含有它们的药物组合物及其用于治疗由S1P1受体介导的各种疾病的用途。

3. 发明申请

US20120101124A1 1,2,4-OXADIAZOL DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS SPHINGOSINE 1-PHOSPHATE 1 RECEPTOR AGONISTS 审中-公开
标题翻译： 1,2,4-OXADIAZOL衍生物，它们的药物组合物及其作为磷酸酯1磷酸酯1受体激动剂的用途
公开(公告)号：US20120101124A1
公开(公告)日：2012-04-26
申请号：US13379214
申请日：2010-06-17
申请人： Xichen Lin , Feng Ren , Yugui Si
发明人： Xichen Lin , Feng Ren , Yugui Si
IPC分类号： A61K31/437 , A61K31/4439 , C07D413/14 , C07D413/10 , A61K31/4245 , A61P25/00 , A61P29/00 , A61P11/06 , A61P19/02 , A61P1/00 , A61P17/06 , A61P35/00 , A61P35/04 , A61P31/12 , A61P3/10 , A61P9/00 , C07D471/04
CPC分类号： C07D471/04 , C07D413/04 , C07D413/14
摘要： 1,2,4-Oxadiazol derivatives represented by formula (I) useful as sphingosine 1-phosphate 1 (S1P1) receptor agonists, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders mediated via S1P1 receptor are disclosed.
摘要翻译：可用作鞘氨醇1-磷酸1（S1P1）受体激动剂的式（I）表示的1,2,4-恶二唑衍生物，其制备方法，含有它们的药物组合物及其用于治疗通过S1P1受体介导的各种病症的用途披露

4. 发明申请

US20110269738A1 COMPOUNDS 失效
标题翻译：化合物
公开(公告)号：US20110269738A1
公开(公告)日：2011-11-03
申请号：US13096641
申请日：2011-04-28
申请人： Guanghui Deng , Xichen Lin , Feng Ren , Baowei Zhao
发明人： Guanghui Deng , Xichen Lin , Feng Ren , Baowei Zhao
IPC分类号： A61K31/433 , A61K31/454 , A61P25/00 , A61P29/00 , A61P11/06 , A61P9/00 , A61P17/06 , A61P35/00 , A61P35/04 , A61P31/12 , A61P3/10 , C07D417/10 , A61P19/02
CPC分类号： C07D417/10
摘要： The present invention relates to novel compounds having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
摘要翻译：本发明涉及具有药理活性的新化合物，其制备方法，含有它们的药物组合物及其在治疗各种疾病中的用途。

5. 发明申请

US20110086839A1 COMPOUNDS 失效
公开(公告)号：US20110086839A1
公开(公告)日：2011-04-14
申请号：US12999091
申请日：2009-06-18
申请人： Jose Luis Castro Pineiro , Xichen Lin , Quan Liu , Kevin Meng , Feng Ren , David R. Vesey , Baowei Zhao
发明人： Jose Luis Castro Pineiro , Xichen Lin , Quan Liu , Kevin Meng , Feng Ren , David R. Vesey , Baowei Zhao
IPC分类号： A61K31/4245 , C07D413/10 , C07D413/14 , A61K31/454 , A61K31/4545 , A61K31/4439 , A61P25/00
CPC分类号： C07D413/04 , C07D413/14
摘要： The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.

6. 发明申请

US20100010053A1 COMPOUNDS 审中-公开
标题翻译：化合物
公开(公告)号：US20100010053A1
公开(公告)日：2010-01-14
申请号：US12486853
申请日：2009-06-18
申请人： Jose Luis Castro Pineiro , Xichen Lin , Qian Liu , Kevin Meng , Feng Ren , David R. Vesey , Baowei Zhao
发明人： Jose Luis Castro Pineiro , Xichen Lin , Qian Liu , Kevin Meng , Feng Ren , David R. Vesey , Baowei Zhao
IPC分类号： A61K31/4245 , C07D271/06 , A61P37/06 , A61P29/00 , A61P35/00 , A61P1/00
CPC分类号： C07D413/04 , C07D413/14
摘要： The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
摘要翻译：本发明涉及具有药理活性的新型恶二唑衍生物，其制备方法，含有它们的药物组合物及其在治疗各种病症中的用途。

7. 发明授权

US07082377B1 Apparatus for error cancellation for dual diode remote temperature sensors 有权
标题翻译：双二极管远端温度传感器误差装置
公开(公告)号：US07082377B1
公开(公告)日：2006-07-25
申请号：US10792112
申请日：2004-03-03
申请人： Mehmet Aslan , Qing Feng Ren , Richard Henderson
发明人： Mehmet Aslan , Qing Feng Ren , Richard Henderson
IPC分类号： G06F15/00 , G01K7/00 , H01L35/00
CPC分类号： G01K7/01 , G01K2219/00
摘要： A temperature measurement circuit for a dual junction temperature sensor is provided. The temperature measurement circuit is configured to provide separate bias currents to the junctions in the temperature sensor. The temperature measurement circuit includes two signal channels configured to provide an intermediate differential signal from a differential input signal that is received from the temperature sensor. Also, the temperature measurement circuit may include one or more multiplexer circuits that are configured to control the intermediate differential signal. The temperature sensor circuit further includes a control circuit configured to adjust the bias currents and to control the multiplexer circuits such that several different differential voltages can be provided by the signal channels. Additionally, the temperature measurement circuit includes a conversion circuit that is configured to convert the differential voltage to a temperature signal, and to perform error cancellation based on the different differential voltages provided by the signal channels.
摘要翻译：提供了一种双结温度传感器的温度测量电路。温度测量电路被配置为向温度传感器中的接点提供单独的偏置电流。温度测量电路包括两个信号通道，被配置为从温度传感器接收的差分输入信号提供中间差分信号。此外，温度测量电路可以包括被配置为控制中间差分信号的一个或多个多路复用器电路。温度传感器电路还包括配置成调整偏置电流并控制多路复用器电路的控制电路，使得可以由信号通道提供几个不同的差分电压。此外，温度测量电路包括转换电路，其被配置为将差分电压转换为温度信号，并且基于由信号通道提供的不同差分电压来执行误差消除。

8. 发明申请

US20130268243A1 PSEUDO-PHYSICAL MODELING OF DRAWBEAD IN STAMPING SIMULATIONS 有权
标题翻译：在冲压模拟中绘制的PSEUDO-物理建模
公开(公告)号：US20130268243A1
公开(公告)日：2013-10-10
申请号：US13439267
申请日：2012-04-04
申请人： Yinong Shen , Feng Ren , Zhiyong Cedric Xia
发明人： Yinong Shen , Feng Ren , Zhiyong Cedric Xia
IPC分类号： G06F17/50
CPC分类号： G06F17/5018 , B21D22/00 , G06F17/5009 , G06F17/5086 , G06F2217/42
摘要： The stamping of a metal sheet within a stamping die is simulated. The die includes a drawbead running perpendicular to a draw direction. A plurality of successive states are generated for iteratively representing the metal sheet from a blank shape to a final stamped shape. The drawbead is represented as a two-dimensional flat band within a model of the stamping die. Forces acting on the metal sheet are calculated at each successive state to define a next successive state. The calculating step includes a restraining force of the drawbead acting on the metal sheet calculated in response to a predetermined function of a length of the metal sheet engaged in the flat band in respective states. The particular width and location of the flat band achieve improved accuracy of estimating the restraining force.
摘要翻译：模拟冲压模具内金属片的冲压。模具包括垂直于拉伸方向延伸的拉丝珠。生成多个连续状态用于从空白形状到最终冲压形状迭代地表示金属片。拉丝珠在冲压模具的模型内被表示为二维平带。在每个连续状态下计算作用在金属片上的力，以定义下一个连续状态。计算步骤包括响应于在各自状态下接合在平带中的金属片的长度的预定函数计算的作用在金属片上的拉带的约束力。扁平带的特定宽度和位置实现了估计约束力的提高的精度。

9. 发明申请

US20120024034A1 Method to Improve Geometrical Accuracy of an Incrementally Formed Workpiece 有权
标题翻译：提高增量成型工件几何精度的方法
公开(公告)号：US20120024034A1
公开(公告)日：2012-02-02
申请号：US12843990
申请日：2010-07-27
申请人： Feng Ren , Zhiyong Cedric Xia
发明人： Feng Ren , Zhiyong Cedric Xia
IPC分类号： B21D31/00
CPC分类号： B21D5/01 , B21D31/00 , B21D31/005
摘要： A method of incrementally forming a workpiece. The method may include incrementally forming a stiffening feature on the workpiece and incrementally forming a part on the workpiece. A gap between forming tools may be decreased to reform the part.
摘要翻译：一种递增形成工件的方法。该方法可以包括在工件上递增地形成加强特征并且逐渐地在工件上形成部件。可以减小成形工具之间的间隙以改变部件。

10. 发明申请

US20120011915A1 METHOD OF INCREMENTAL FORMING WITH SUCCESSIVE WRAP SURFACES 有权
标题翻译：具有后续形成表面的成型方法
公开(公告)号：US20120011915A1
公开(公告)日：2012-01-19
申请号：US12836989
申请日：2010-07-15
申请人： Vijitha Senaka Kiridena , Feng Ren , Zhiyong Cedric Xia
发明人： Vijitha Senaka Kiridena , Feng Ren , Zhiyong Cedric Xia
IPC分类号： B21D31/00
CPC分类号： B21D3/02 , B21D31/00 , B21D31/005
摘要： A method of incrementally forming a workpiece. The method includes incrementally forming a first monotonic wrap surface in a first direction and incrementally forming a second wrap surface in a second direction disposed opposite the first direction.
摘要翻译：一种递增形成工件的方法。该方法包括在第一方向逐渐地形成第一单调包裹表面，并且沿与第一方向相反的第二方向递增地形成第二包裹表面。

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