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1. 发明授权

US09920264B2 Process of hydroconversion-distillation of heavy and/or extra-heavy crude oils 有权
公开(公告)号：US09920264B2
公开(公告)日：2018-03-20
申请号：US13598684
申请日：2012-08-30
申请人： Jorge Ancheyta Juarez , Jose Antonio Domingo Muñoz Moya , Luis Carlos Castañeda Lopez , Sergio Ramirez Amador , Gustavo Jesus Marroquin Sanchez , Guillermo Centeno Nolasco , Fernando Alonso Martinez , Rodolfo Antonio Aguilar Escalante
发明人： Jorge Ancheyta Juarez , Jose Antonio Domingo Muñoz Moya , Luis Carlos Castañeda Lopez , Sergio Ramirez Amador , Gustavo Jesus Marroquin Sanchez , Guillermo Centeno Nolasco , Fernando Alonso Martinez , Rodolfo Antonio Aguilar Escalante
IPC分类号： C10G67/16 , C10G67/00 , C10G45/08 , C10G47/12 , C10G47/14 , C10G65/12 , C10G65/14
CPC分类号： C10G67/00 , C10G45/08 , C10G47/12 , C10G47/14 , C10G65/12 , C10G65/14 , C10G2300/201 , C10G2300/308
摘要： A process for hydroconversion-distillation of heavy and/or extra-heavy crude oils, which comprises four stages: 1) desalting and separation of the feedstock; 2) catalytic hydrotreating of light fraction (optional); 3) catalytic hydroconversion of heavy fraction, and 4) distillation of hydrotreated products to provide products that can be processed in conventional refining schemes designed to operate with light and intermediate crude oils.

2. 发明申请

US20130056394A1 PROCESS OF HYDROCONVERSION-DISTILLATION OF HEAVY AND/OR EXTRA-HEAVY CRUDE OILS 有权
标题翻译：重油和/或超重油原油的氢化转化方法
公开(公告)号：US20130056394A1
公开(公告)日：2013-03-07
申请号：US13598684
申请日：2012-08-30
申请人： Jorge ANCHEYTA JUAREZ , Jose Antonio Domingo MUNOZ MOYA , Luis Carlos CASTANEDA LOPEZ , Sergio RAMIREZ AMADOR , Gustavo Jesus MARROQUIN SANCHEZ , Guillermo CENTENO NOLASCO , Fernando ALONSO MARTINEZ , Rodolfo Antonio AGUILAR ESCALANTE
发明人： Jorge ANCHEYTA JUAREZ , Jose Antonio Domingo MUNOZ MOYA , Luis Carlos CASTANEDA LOPEZ , Sergio RAMIREZ AMADOR , Gustavo Jesus MARROQUIN SANCHEZ , Guillermo CENTENO NOLASCO , Fernando ALONSO MARTINEZ , Rodolfo Antonio AGUILAR ESCALANTE
IPC分类号： C10G67/16 , C10G67/04
CPC分类号： C10G67/00 , C10G45/08 , C10G47/12 , C10G47/14 , C10G65/12 , C10G65/14 , C10G2300/201 , C10G2300/308
摘要： A process for hydroconversion-distillation of heavy and/or extra-heavy crude oils, which comprises four stages: 1) desalting and separation of the feedstock; 2) catalytic hydrotreating of light fraction (optional); 3) catalytic hydroconversion of heavy fraction, and 4) distillation of hydrotreated products to provide products that can be processed in conventional refining schemes designed to operate with light and intermediate crude oils.
摘要翻译：重质和/或超重原油的加氢转化 - 蒸馏方法，其包括四个阶段：1）原料的脱盐和分离; 2）轻馏分的催化加氢处理（任选）; 3）重馏分的催化加氢转化，以及4）加氢处理产物的蒸馏，以提供可以用设计用于轻质和中间原油操作的常规精炼方案中加工的产物。

3. 发明授权

US07968069B2 Catalyst, its preparation and use for hydrodesulfurization of residua and heavy crudes 有权
标题翻译：催化剂，其制备和用于残渣和重质原油的加氢脱硫
公开(公告)号：US07968069B2
公开(公告)日：2011-06-28
申请号：US11582552
申请日：2006-10-18
申请人： Patricia Rayo Mayoral , Jorge Ancheyta Juárez , Jorge Fernando Ramírez Solis , Samir Kumar Maity , Mohan Singh Rana , Fernando Alonso Martínez
发明人： Patricia Rayo Mayoral , Jorge Ancheyta Juárez , Jorge Fernando Ramírez Solis , Samir Kumar Maity , Mohan Singh Rana , Fernando Alonso Martínez
IPC分类号： B01D47/06 , B01J20/00
CPC分类号： B01J37/0009 , B01J21/063 , B01J23/85 , B01J23/883 , B01J35/1019 , B01J35/1038 , B01J35/1042 , B01J35/1061 , B01J35/108 , B01J37/0207 , C10G45/08 , C10G65/04 , C10G2300/1033 , C10G2300/202 , C10G2300/206 , C10G2300/703
摘要： A catalyst for hydrotreating, especially hydrodesulfurization, of residua and heavy crudes is prepared by synthesizing the support from titanium and boehmite, to form either a titanium/alumina support (TiO2/Al2O3) or a titanium-alumina support (TiO2—Al2O3) that is thereafter provided with at least one hydrogenating metal from group VIB in oxide form and a promoter from group VIII also in oxide form. The (TiO2/Al2O3) support is prepared from boehmite, which is peptized by using an inorganic acid, then extruded, calcined and impregnated with a solution containing titanium, while the (TiO2—Al2O3) support is prepared by admixing boehmite with a titanium-containing solution, peptized using an inorganic acid, extruded and calcined to obtain the titanium-alumina support.
摘要翻译：通过合成钛和勃姆石的载体，形成钛/氧化铝载体（TiO 2 / Al 2 O 3）或钛 - 氧化铝载体（TiO 2 -Al 2 O 3）制备用于加氢处理，特别是加氢脱硫的残余物和重质原油的催化剂，然后提供至少一种氧化物形式的VIB的氢化金属和氧化物形式的来自VIII族的助催化剂。（TiO 2 / Al 2 O 3）载体由勃姆石制备，其通过使用无机酸胶化，然后用含钛的溶液进行挤出，煅烧和浸渍，而（TiO 2 -Al 2 O 3）载体通过将勃姆石与钛 - 使用无机酸胶溶，挤出和煅烧以获得钛 - 氧化铝载体。

4. 发明授权

US06643568B2 System for automatically controlling lift-augmentation devices of an aircraft during take-off 有权
标题翻译：起飞时自动控制飞机起升装置的系统
公开(公告)号：US06643568B2
公开(公告)日：2003-11-04
申请号：US09988264
申请日：2001-11-19
申请人： Dominique Chatrenet , Gérard Mathieu , Fernando Alonso , Martine Cart-Lamy
发明人： Dominique Chatrenet , Gérard Mathieu , Fernando Alonso , Martine Cart-Lamy
IPC分类号： G06F1900
CPC分类号： G05D1/0661 , G05D1/0077
摘要： A system for automatically controlling lift augmentation devices of an aircraft, during a phase of take-off by the aircraft, includes a controllable actuator that shifts the lift-augmentation devices, and a control unit for generating control demands to control the actuator to bring the lift-augmentation devices into a defined position. The control unit further includes a detector that detects actual take-off by the air craft and, if appropriate, signals such detection to the control unit. At start of the take-off phase, the lift-augmentation device are brought into a first position, in which they are deployed. The control unit generates, at least when the detector signals the actual take-off, a control demand making it possible to bring the lift-augmentation devices into a second position, in which the lift-augmentation devices are retracted by comparison with the first position.
摘要翻译：一种用于在飞行器起飞阶段期间自动控制升降机增强装置的系统，包括可升降增加装置移动的可控致动器，以及用于产生控制要求以控制致动器带动升降装置进入限定位置。控制单元还包括检测器，其检测飞行器的实际起飞，并且如果适当的话，将这种检测信号发送到控制单元。在起飞阶段开始时，提升装置进入其展开的第一位置。控制单元至少在检测器发出实际的起飞时产生控制要求，从而使提升增加装置能够进入第二位置，在第二位置，提升增加装置与第一位置相比缩回。

5. 发明授权

US08871725B2 Pharmaceutical combination for the treatment and/or chemosensibilization of refractory tumors to anticancer drugs 有权
$Pharmaceutical combination for the treatment and/or chemosensibilization of refractory tumors to anticancer drugs$
标题翻译：用于治疗和/或耐药肿瘤对抗癌药物的化学敏化的药物组合
公开(公告)号：US08871725B2
公开(公告)日：2014-10-28
申请号：US12280629
申请日：2007-02-28
申请人： Silvio Ernesto Perea Rodriguez , Yasser Perera Negrin , Arielis Rodriguez Ulloa , Jeovanis Gil Valdés , Yassel Ramos Gómez , Lila Rosa Castellanos Serra , Lázaro Hiram Betancourt Núñez , Aniel Sánchez Puente , Jorge Fernández de Cossio Dorta Duque , Boris Ernesto Acevedo Castro , Luis Javier González López , Vladimir Besada Pérez , Daniel Fernando Alonso , Daniel Eduardo Gomez
发明人： Silvio Ernesto Perea Rodriguez , Yasser Perera Negrin , Arielis Rodriguez Ulloa , Jeovanis Gil Valdés , Yassel Ramos Gómez , Lila Rosa Castellanos Serra , Lázaro Hiram Betancourt Núñez , Aniel Sánchez Puente , Jorge Fernández de Cossio Dorta Duque , Boris Ernesto Acevedo Castro , Luis Javier González López , Vladimir Besada Pérez , Daniel Fernando Alonso , Daniel Eduardo Gomez
IPC分类号： A61K38/08 , A61K39/00 , C07K7/06 , A61P35/00 , A61K45/06 , A61K33/24 , A61K31/555
CPC分类号： A61K38/08 , A61K31/136 , A61K31/282 , A61K31/337 , A61K31/407 , A61K31/475 , A61K31/506 , A61K31/513 , A61K31/5377 , A61K31/555 , A61K31/675 , A61K31/69 , A61K31/704 , A61K31/7048 , A61K31/7068 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
摘要： This invention is related to a pharmaceutical combination that contains a Casein kinase 2 (CK2) peptide inhibitor (termed P15) along with the standard chemotherapeutic drugs used in cancer treatment and which are administered together, separated or sequentially. The chemotherapeutic drugs include cisplatin, taxol, alkaloids from Vinca, 5-fluorouracil, doxorubicin, cyclophosphamide, etoposide, mitomicin C, imatinib, iressa and velcade (vortezomib). The synergism between the P15 peptide and the anticancer drugs achieves an efficient concentration of each cytostatic drug in the combination which is from 10- to 100-fold lower than that for each cytostatic drug alone. The pharmaceutical combination described in this invention exhibits lower toxicity compared to that reported by the anticancer therapeutics and therefore, it represents a crucial advantage for its use in cancer therapy. Furthermore, the sequential administration of this pharmaceutical combination through the pretreatment with the P15 peptide leads to the chemo sensibilization of refractory tumors to the anticancer therapeutics.
摘要翻译：本发明涉及含有酪蛋白激酶2（CK2）肽抑制剂（称为P15）以及癌症治疗中使用的标准化学治疗药物并且分开或依次给药的药物组合。化疗药物包括顺铂，紫杉醇，长春花生物碱，5-氟尿嘧啶，多柔比星，环磷酰胺，依托泊苷，mitomicin C，伊马替尼，iressa和velcade（vortezomib）。 P15肽与抗癌药物之间的协同作用实现了组合中每种细胞抑制药物的有效浓缩，其比单独的每种细胞抑制药物低10至100倍。本发明中描述的药物组合物与抗癌治疗剂报道的药物组合物相比表现出较低的毒性，因此它代表其用于癌症治疗的关键优势。此外，通过用P15肽进行预处理，该药物组合的连续施用导致难治性肿瘤对抗癌治疗剂的化学敏感性。

6. 发明授权

US08705892B2 Generating three-dimensional virtual tours from two-dimensional images 有权
标题翻译：从二维图像生成三维虚拟旅游
公开(公告)号：US08705892B2
公开(公告)日：2014-04-22
申请号：US13226695
申请日：2011-09-07
申请人： Jaime Aguilera , Fernando Alonso , Juan Bautista Gomez
发明人： Jaime Aguilera , Fernando Alonso , Juan Bautista Gomez
IPC分类号： G06K9/00 , G06K9/36 , G06T15/00 , G09G5/00
CPC分类号： G06T19/003 , G06F17/30873 , G06T15/20
摘要： Interactive three-dimensional (3D) virtual tours are generated from ordinary two-dimensional (2D) still images such as photographs. Two or more 2D images are combined to form a 3D scene, which defines a relationship among the 2D images in 3D space. 3D pipes connect the 2D images with one another according to defined spatial relationships and for guiding virtual camera movement from one image to the next. A user can then take a 3D virtual tour by traversing images within the 3D scene, for example by moving from one image to another, either in response to user input or automatically. In various embodiments, some or all of the 2D images can be selectively distorted to enhance the 3D effect, and thereby reinforce the impression that the user is moving within a 3D space. Transitions from one image to the next can take place automatically without requiring explicit user interaction.
摘要翻译：从诸如照片的普通二维（2D）静止图像生成交互式三维（3D）虚拟游览。将两个或更多个2D图像组合以形成3D场景，其定义3D空间中的2D图像之间的关系。 3D管道根据定义的空间关系将2D图像彼此连接，并用于引导从一个图像到下一个图像的虚拟相机移动。然后，用户可以通过遍历3D场景内的图像来进行3D虚拟游览，例如通过响应于用户输入或自动地从一个图像移动到另一个图像。在各种实施例中，可以选择性地扭曲部分或全部2D图像以增强3D效果，从而增强用户在3D空间内移动的印象。从一个图像到下一个图像的转换可以自动进行，而不需要明确的用户交互。

7. 发明授权

US08431018B2 Carbon supported catalyst for demetallation of heavy crude oil and residue 有权
标题翻译：用于重质原油和残渣脱金属的碳负载催化剂
公开(公告)号：US08431018B2
公开(公告)日：2013-04-30
申请号：US12716776
申请日：2010-03-03
申请人： Samir Kumar Maity , Jorge Ancheyta Juárez , Fernando Alonso Martínez , Hidetsugu Fukuyama , Satoshi Terai , Masayuki Uchida
发明人： Samir Kumar Maity , Jorge Ancheyta Juárez , Fernando Alonso Martínez , Hidetsugu Fukuyama , Satoshi Terai , Masayuki Uchida
IPC分类号： C10G45/60 , B01J21/18
CPC分类号： C10G45/04 , B01J21/18 , B01J23/88 , B01J27/19 , B01J35/1042 , B01J35/1047 , B01J35/108 , B01J37/0009 , B01J37/10 , B01J37/20 , C10G45/06
摘要： A supported carbon having high surface area, high pore volume containing (i) molybdenum (ii) a metal of non noble Group VIII, (iii) phosphorous, is used for hydrometallization of heavy crude oil and residue. The catalyst contains about 6 to 15 wt % molybdenum as MoO3, about 1 to 6 wt % cobalt or nickel as CoO or NiO and phosphorus as phosphorous oxide. One characteristic of the catalyst is the portion of pores having pore diameter in the range of 200 to 2000 Angstrom of 20 percent or more. The catalyst prepared by chelating agent has higher hydrodesulfurization activity assuming that more dispersed active metals are present on this catalyst. Long run activity studies show that catalyst having only molybdenum supported on activated carbon has good stability with time-on-stream and very high metal retention capacity.
摘要翻译：具有高表面积，高孔体积的载体碳含有（i）钼（ii）非贵金属第VIII族金属，（iii）磷，用于重质原油和残余物的湿法化。催化剂含有约6至15重量％的钼作为MoO 3，约1至6重量％的钴或镍作为CoO或NiO，磷作为氧化磷。催化剂的一个特征是孔径在200至2000埃范围内的孔的部分为20％或更多。假设催化剂上存在更多分散的活性金属，螯合剂制备的催化剂具有较高的加氢脱硫活性。长时间活性研究表明，仅在催化剂上活性炭负载的催化剂具有良好的稳定性，并具有很高的金属保留能力。

8. 发明申请

US20120099804A1 Generating Three-Dimensional Virtual Tours From Two-Dimensional Images 有权
标题翻译：从二维图像生成三维虚拟旅游
公开(公告)号：US20120099804A1
公开(公告)日：2012-04-26
申请号：US13226695
申请日：2011-09-07
申请人： Jaime Aguilera , Fernando Alonso , Juan Bautista Gomez
发明人： Jaime Aguilera , Fernando Alonso , Juan Bautista Gomez
IPC分类号： G06K9/36
CPC分类号： G06T19/003 , G06F17/30873 , G06T15/20
摘要： Interactive three-dimensional (3D) virtual tours are generated from ordinary two-dimensional (2D) still images such as photographs. Two or more 2D images are combined to form a 3D scene, which defines a relationship among the 2D images in 3D space. 3D pipes connect the 2D images with one another according to defined spatial relationships and for guiding virtual camera movement from one image to the next. A user can then take a 3D virtual tour by traversing images within the 3D scene, for example by moving from one image to another, either in response to user input or automatically. In various embodiments, some or all of the 2D images can be selectively distorted to enhance the 3D effect, and thereby reinforce the impression that the user is moving within a 3D space. Transitions from one image to the next can take place automatically without requiring explicit user interaction.
摘要翻译：从诸如照片的普通二维（2D）静止图像生成交互式三维（3D）虚拟游览。将两个或更多个2D图像组合以形成3D场景，其定义3D空间中的2D图像之间的关系。 3D管道根据定义的空间关系将2D图像彼此连接，并用于引导从一个图像到下一个图像的虚拟相机移动。然后，用户可以通过遍历3D场景内的图像来进行3D虚拟游览，例如通过响应于用户输入或自动地从一个图像移动到另一个图像。在各种实施例中，可以选择性地扭曲部分或全部2D图像以增强3D效果，从而增强用户在3D空间内移动的印象。从一个图像到下一个图像的转换可以自动进行，而不需要明确的用户交互。

9. 发明申请

US20070187294A1 Process for the catalytic hydrotretment of heavy hydrocarbons of petroleum 有权
标题翻译：石油重烃催化加氢处理工艺
公开(公告)号：US20070187294A1
公开(公告)日：2007-08-16
申请号：US10563577
申请日：2003-07-09
申请人： Jorge Ancheyta Juarez , Gerardo Betancourt Rivera , Gustavo Marroquin Sanchez , Guillermo Centeno Nolasco , Jose Antonio Domingo Munoz Maya , Fernando Alonso Martinez
发明人： Jorge Ancheyta Juarez , Gerardo Betancourt Rivera , Gustavo Marroquin Sanchez , Guillermo Centeno Nolasco , Jose Antonio Domingo Munoz Maya , Fernando Alonso Martinez
IPC分类号： C10G65/00 , C10G1/00 , C10G45/00 , C10G17/00 , C10G69/00 , C10G47/00
CPC分类号： C10G65/02 , C10G45/02 , C10G65/12 , C10G2300/1033 , C10G2300/107 , C10G2300/1077 , C10G2300/202 , C10G2300/205 , C10G2300/206 , C10G2300/308 , C10G2300/4006 , C10G2300/4012 , C10G2300/4018
摘要： Two-stage low pressure catalytic hydrotreatment of heavy petroleum hydrocarbons having a high content of contaminants (metals and asphaltenes), is conducted under operating conditions with low-pressure, in a fixed bed or ebullated bed reactor to limit the formation of sediments and sludge in the product and obtain a hydrotreated hydrocarbon of improved properties, with levels of contaminants, API gravity and distillates within the ranges commonly reported in the feedstocks typical to refining schemes. A hydrotreatment catalyst, whose principal effect is the hydrodemetallization and the hydrocracking of asphaltenes of the heavy hydrocarbons of petroleum is used in the first stage, and the second reaction stage employs a hydrotreatment catalyst for a deeper effect of hydrodesulfurization of the heavy petroleum hydrocarbon whose content of total sulfur is reduced to a level required for its treatment in the conventional refining process or for its sale as a hydrocarbon of petroleum with improved properties.
摘要翻译：在低压的操作条件下，在固定床或沸腾床反应器中进行具有高含量污染物（金属和沥青质）的重质石油烃的两级低压催化加氢处理，以限制沉积物和污泥的形成该产品并获得改进性能的加氢处理烃，其污染物含量，API重力和馏出物在精炼方案典型的原料中通常报告的范围内。第一阶段采用加氢处理催化剂，其主要作用是加氢脱金属和石油中重质烃沥青质的加氢裂化，第二反应阶段采用加氢处理催化剂，对重质烃的加氢脱硫作用较深，其含量的总硫减少到在常规精炼过程中其处理所需的水平或作为具有改进性能的石油烃的销售。

10. 发明授权

US06693082B2 Method of inhibiting metastatic dissemination using desmopressin 有权
标题翻译：使用去氨加压素抑制转移性传播的方法
公开(公告)号：US06693082B2
公开(公告)日：2004-02-17
申请号：US09875671
申请日：2001-06-05
申请人： Daniel Fernando Alonso , Daniel Eduardo Gomez , Guillermo Skilton , Eduardo Francisco Faríias , Elisa Dora Bal de Kier Joffé
发明人： Daniel Fernando Alonso , Daniel Eduardo Gomez , Guillermo Skilton , Eduardo Francisco Faríias , Elisa Dora Bal de Kier Joffé
IPC分类号： A61K3811
CPC分类号： A61K38/11
摘要： The present invention relates to the use of 1-deamino-8-D-arginine vasopressin (desmopressin), or a pharmaceutically acceptable salt thereof or a pharmaceutical composition containing any of them, in the preparation of a medication which minimizes metastatic dissemination during cancer surgery. Additionally, the invention also relates to pharmaceutical compositions comprising the same and to a method of treating a mammal in order to inhibit metastatic spread during surgical extirpation of a cancer mass.
摘要翻译：本发明涉及1-脱氨基-8-D-精氨酸加压素（去氨加压素）或其药学上可接受的盐或其任何一种的药物组合物在制备癌症手术期间最小化转移性传播的药物中的用途。此外，本发明还涉及包含该组合物的药物组合物和治疗哺乳动物以抑制癌肿块体外科手术拔除期间的转移性扩散的方法。

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