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1. 发明授权

US10286073B2 Magnetic control of gene delivery in vivo 有权
公开(公告)号：US10286073B2
公开(公告)日：2019-05-14
申请号：US15441089
申请日：2017-02-23
申请人： Haibao Zhu , Sheng Tong , Gang Bao
发明人： Haibao Zhu , Sheng Tong , Gang Bao
IPC分类号： A61K48/00 , C12N15/866 , C12N9/22 , A61K41/00 , A61K9/107 , C12N15/113 , A61K47/69 , C12N15/87 , A61K9/50
摘要： This disclosure describes a composition and method of magnetic nanoparticles (MNP) that are bound to a baculovirus (BV). The MNP-BV can be systemically administered to a patient, and a strong magnetic field applied to the target tissue, thus allowing uptake and expression only in the target tissue. Off-target effects are not seen because the MNP-BC is inactivated by the complement system outside of the magnetic field.

2. 发明申请

US20140322818A1 Nanocrystal Based Biomolecule Detection 审中-公开
标题翻译：基于纳米晶体的生物分子检测
公开(公告)号：US20140322818A1
公开(公告)日：2014-10-30
申请号：US13869780
申请日：2013-04-24
申请人： Gang Bao , Sheng Tong
发明人： Gang Bao , Sheng Tong
IPC分类号： G01N33/543
CPC分类号： G01N33/54306 , G01N33/553 , G01N33/588
摘要： A new signal amplification method exploiting the dense atom packing in metallic nanocrystals has been developed for detecting target substances. By dissolving nanocrystals to individual ions that are stoichiometrically converted to chromophores and quantified photometrically, extremely high signal amplification can be achieved. Signal amplification is fully determined by the total number of atoms in the nanocrystals bound to a single target molecule. The disclosed nanocrystal amplification method can be implemented with a rich selection of metal/metal oxide nanocrystals and metal-reactive chromogenic substrates. The chromogenic reactions can be either solution-based or surface-based and performed in aqueous or organic phase, supporting a variety of assay formats
摘要翻译：开发了一种利用金属纳米晶体中的致密原子填充的新型信号放大方法，用于检测目标物质。通过将纳米晶体溶解在化学计量转换为发色团的个别离子上并进行光度测量，可以实现极高的信号放大。信号放大完全由与单个靶分子结合的纳米晶体中的原子总数决定。所公开的纳米晶体扩增方法可以用丰富的金属/金属氧化物纳米晶体和金属反应性显色底物的选择来实现。显色反应可以是基于溶液的或基于表面的，并且在水相或有机相中进行，支持各种测定形式

3. 发明申请

US20120106445A1 METHOD AND APPARATUS FOR ESTABLISHING AN INTERFACE BETWEEN ACCESS POINTS 有权
标题翻译：用于建立接入点之间接口的方法和装置
公开(公告)号：US20120106445A1
公开(公告)日：2012-05-03
申请号：US13096758
申请日：2011-04-28
申请人： Gavin Bernard Horn , Osok Song , Gang Bao
发明人： Gavin Bernard Horn , Osok Song , Gang Bao
IPC分类号： H04W48/20
CPC分类号： H04W8/26 , H04W92/20
摘要： Methods and apparatuses are provided that facilitate establishing an interface for communications between access points. Where access points operate in a same local or enterprise network, an interface can be established via the local or enterprise network instead of (or in addition to) a wireless operator network. A source access point can determine an address over which to request establishment of the interface based at least in part on an identifier of a target access point. In another example, target access point can determine an address to provide to the source access point for establishing the interface based at least in part on an identifier of the source access point.
摘要翻译：提供了便于建立用于接入点之间的通信的接口的方法和装置。当接入点在相同的本地或企业网络中运行时，可以通过本地或企业网络建立接口，而不是（或除了）无线运营商网络。源接入点可以至少部分地基于目标接入点的标识符来确定请求建立接口的地址。在另一个示例中，目标接入点可以至少部分地基于源接入点的标识来确定提供给源接入点以建立接口的地址。

4. 发明申请

US20100226814A1 LOW-THERMAL-EXPANSION NI-BASED SUPER-HEAT-RESISTANT ALLOY FOR BOILER AND HAVING EXCELLENT HIGH-TEMPERATURE STRENGTH, AND BOILER COMPONENT AND BOILER COMPONENT PRODUCTION METHOD USING THE SAME 有权
标题翻译：用于锅炉的低热膨胀的基于镍的超耐热合金和具有优异的高温强度的锅炉组件和锅炉组件的生产方法
公开(公告)号：US20100226814A1
公开(公告)日：2010-09-09
申请号：US12675688
申请日：2008-08-29
申请人： Toshihiro Uehara , Takehiro Ohno , Akihiro Toji , Takashi Sato , Gang Bao , Shinya Imano , Hiroyuki Doi
发明人： Toshihiro Uehara , Takehiro Ohno , Akihiro Toji , Takashi Sato , Gang Bao , Shinya Imano , Hiroyuki Doi
IPC分类号： C22C19/05 , C22F1/10
CPC分类号： C22C19/055 , C22F1/10 , F28F21/083
摘要： Disclosed is a low-thermal-expansion Ni-based super-heat-resistant alloy for a boiler, which has excellent high-temperature strength. The alloy can be welded without the need of carrying out any aging treatment. The alloy has a Vickers hardness value of 240 or less. The alloy comprises (by mass) C in an amount of 0.2% or less, Si in an amount of 0.5% or less, Mn in an amount of 0.5% or less, Cr in an amount of 10 to 24%, one or both of Mo and W in such an amount satisfying the following formula: Mo+0.5 W=5 to 17%, Al in an amount of 0.5 to 2.0%, Ti in an amount of 1.0 to 3.0%, Fe in an amount of 10% or less, and one or both of B and Zr in an amount of 0.02% or less (excluding 0%) for B and in an amount of 0.2% or less (excluding 0%) for Zr, with the remainder being 48 to 78% of Ni and unavoidable impurities.
摘要翻译：公开了一种用于锅炉的低热膨胀Ni基超耐热合金，其具有优异的高温强度。可以焊接合金，而不需要进行任何时效处理。该合金的维氏硬度值为240以下。该合金含有0.2质量％以下的Si（以质量计），0.5％以下的Si，0.5％以下的Mn，10〜24％的Cr，1种或2种的Mo和W的量满足下式：Mo + 0.5W = 5〜17％，Al为0.5〜2.0％，Ti为1.0〜3.0％，Fe为10％以下的B和Zr中的一种或两种，B的含量为0.02％以下（不含0％），Zr的含量为0.2％以下（不含0％），余量为48〜78 ％的Ni和不可避免的杂质。

5. 发明申请

US20060210979A1 Methods of detecting gene expression in normal and cancerous cells 审中-公开
标题翻译：检测正常和癌细胞基因表达的方法
公开(公告)号：US20060210979A1
公开(公告)日：2006-09-21
申请号：US10542117
申请日：2004-01-13
申请人： Lily Yang , Gang Bao , Charles Staley , Cynthia Cohen
发明人： Lily Yang , Gang Bao , Charles Staley , Cynthia Cohen
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6818 , C12Q1/6886 , C12Q2600/156 , C12Q2600/158 , C12Q2565/1015 , C12Q2525/301
摘要： The present invention provides methods for detecting gene expression in normal and cancerous cells. Specifically, provided are methods utilizing molecular beacons (MB) technology combined with fluorescence imaging techniques for detecting, identifying or quantitating the presence of, or alterations in gene expression of, various tumor markers in a sample of cells.
摘要翻译：本发明提供了检测正常和癌细胞中基因表达的方法。具体地，提供了利用分子信标（MB）技术与荧光成像技术相结合的方法，用于检测，鉴定或定量细胞样品中各种肿瘤标志物的存在或基因表达的改变。

6. 发明授权

US07081336B2 Dual resonance energy transfer nucleic acid probes 失效
公开(公告)号：US07081336B2
公开(公告)日：2006-07-25
申请号：US10179730
申请日：2002-06-25
申请人： Gang Bao , Andrew Tsourkas , Yangqing Xu
发明人： Gang Bao , Andrew Tsourkas , Yangqing Xu
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6818 , C12Q2565/101 , C12Q2525/301
摘要： Dual nucleic acid probes with resonance energy transfer moieties are provided. In particular, fluorescent or luminescent resonance energy transfer moieties are provided on hairpin stem-loop molecular beacon probes that hybridize sufficiently near each other on a subject nucleic acid, e.g. mRNA, to generate an observable interaction. The invention also provides lanthanide chelate luminescent resonance energy transfer moieties on linear and stem-loop probes that hybridize sufficiently near each other on a subject nucleic acid to generate an observable interaction. The invention thereby provides detectable signals for rapid, specific and sensitive hybridization determination in vivo. The probes are used in methods of detection of nucleic acid target hybridization for the identification and quantification of tissue and cell-specific gene expression levels, including response to external stimuli, such as drug candidates, and genetic variations associated with disease, such as cancer.

7. 发明申请

US20050254465A1 Method and apparatus for determining a data rate in a high rate packet data wireless communications system 有权
公开(公告)号：US20050254465A1
公开(公告)日：2005-11-17
申请号：US11165882
申请日：2005-06-24
申请人： Stein Lundby , Leonid Razoumov , Gang Bao , Yongbin Wei
发明人： Stein Lundby , Leonid Razoumov , Gang Bao , Yongbin Wei
IPC分类号： H04B7/26 , H04B7/005 , H04L12/56 , H04W28/22 , H04W52/16 , H04W52/26 , H04W52/28 , H04W52/32 , H04W52/34 , H04B7/216
CPC分类号： H04W28/22 , H04L1/0002 , H04L1/0026 , H04W52/16 , H04W52/267 , H04W52/286 , H04W52/325 , H04W52/346
摘要： In a wireless communication system a method for combination transmission of packet data and low delay data. In one embodiment a parallel signaling channel provides a message to receivers indicating a target recipient of packet data. The message also identifies the transmission channels used for packet data transmissions. Each receiver may then selectively decode only packets where the message identifies the receiver as a target recipient. The data packets stored in a buffer are ignored if the target recipient is another mobile unit. In one embodiment, the message is sent concurrently with the data packet on a parallel channel. In one embodiment, the message is punctured into the high rate packet data transmission.

8. 发明申请

US20050063332A1 Forward-link scheduling in a wireless communication system 失效
公开(公告)号：US20050063332A1
公开(公告)日：2005-03-24
申请号：US10972199
申请日：2004-10-22
申请人： Jack Holtzman , Gang Bao
发明人： Jack Holtzman , Gang Bao
IPC分类号： H04J13/00 , H04B7/005 , H04B7/26 , H04L1/00 , H04L12/28 , H04W52/16 , H04W52/22 , H04W52/26 , H04W52/50 , H04W72/12 , H04Q7/00
CPC分类号： H04W72/1226 , H04L1/0002 , H04L1/0015 , H04L1/0046 , H04W52/16 , H04W52/223 , H04W52/26 , H04W52/50 , H04W72/1242
摘要： A method and apparatus for selecting a favored transmission slot for communicating non-voice data in conjunction with a voice-data communication. The slot, reflecting a favored power level and transmission rate for transmitting the non-voice data on a supplemental channel, is selected based upon the transmission power levels for voice-data transmitted by a base station to a remote station on a fundamental channel. The favored transmission slot is selected without the remote station messaging information to the base station concerning frequency channel or interference information for the supplemental channel. A method of performing forward-link scheduling in a wireless communication system includes determining the available base station power at the beginning of a frame, predicting the required transmit power at the beginning of the frame for each supplemental channel, determining rates sustainable with the predicted transmit power, dividing by throughput over a recent window to obtain a supplemental channel priority index, and allowing the supplemental channel with the highest priority index to transmit over the next frame.

9. 发明授权

US06788687B2 Method and apparatus for scheduling packet data transmissions in a wireless communication system 失效
标题翻译：一种用于在无线通信系统中调度分组数据传输的方法和装置
公开(公告)号：US06788687B2
公开(公告)日：2004-09-07
申请号：US10001610
申请日：2001-10-30
申请人： Gang Bao , David Puig Oses
发明人： Gang Bao , David Puig Oses
IPC分类号： H04L1250
CPC分类号： H04L1/1867 , H04L47/14 , H04L47/70 , H04L47/765 , H04L47/805 , H04L47/824 , H04W28/10
摘要： A method for scheduling packet data transmissions in a wireless communication system wherein a per-user Priority Function (PF) is calculated based on the channel condition and throughput for each user. In one embodiment, the system supports retransmission of data packets and sub-packets, wherein the retransmission information is used to schedule data transmissions. In another embodiment, at each time interval the system updates the priority factor for the user having the highest priority factor in the previous time interval. The priority factors of the other users remain unchanged.
摘要翻译：一种用于在无线通信系统中调度分组数据传输的方法，其中基于每个用户的信道条件和吞吐量来计算每用户优先级功能（PF）。在一个实施例中，系统支持数据分组和子分组的重传，其中重传信息用于调度数据传输。在另一个实施例中，在每个时间间隔，系统更新在先前时间间隔中具有最高优先级因子的用户的优先级因子。其他用户的优先级因素保持不变。

10. 外观设计

USD425577S Toy crane excavator 失效
公开(公告)号：USD425577S
公开(公告)日：2000-05-23
申请号：US100903
申请日：1999-02-22
申请人： Wei Gang Bao
设计人： Wei Gang Bao

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