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1. 发明授权

US11175289B2 Application of TRPM8 protein, related peptide fragment and their antibodies 有权
公开(公告)号：US11175289B2
公开(公告)日：2021-11-16
申请号：US15352607
申请日：2016-11-16
申请人： Lei Han , Xiaohui Zhou , Yuyan Zhou , Li Zhou , Guohua Li , Yongzhen Li
发明人： Lei Han , Xiaohui Zhou , Yuyan Zhou , Li Zhou , Guohua Li , Yongzhen Li
IPC分类号： C07K14/705 , G01N33/564 , C07K16/28
摘要： A TRPM8 related peptide fragment, comprising amino acid sequence as shown in SEQ ID No: 1-18 is provided. Furthermore, application of TRPM8 protein, TRPM8 related peptide fragment and their antibodies in preparing diagnostic reagent for chronic prostatitis/chronic pelvic pain syndromes (CP/CPPS) is provided. By detecting level of TRPM8 protein molecule, TRPM8 related peptide fragment and their antibodies, the chronic prostatitis/chronic pelvic pain syndromes (CP/CPPS) is effectively diagnosed, and the present invention is capable of effectively making a distinction between CP/CPPS and other diseases of prostate. In addition, by intravenously or subcutaneously injecting 1˜30000 IU TRPM8 protein or TRPM8 related polypeptide fragments with or without combining nanoparticles for desensitization therapy, or monoclonal or polyclonal antibodies of the TRPM8 protein or polypeptide fragments, the present invention is capable of curing or significantly relieve clinical symptoms of the chronic prostatitis/chronic pelvic pain syndromes (CP/CPPS) and having an therapeutic effect.

2. 再颁专利

USRE46187E1 Positive electrode material and battery using the same 有权
标题翻译：正极材料和使用其的电池
公开(公告)号：USRE46187E1
公开(公告)日：2016-10-25
申请号：US12101800
申请日：2008-04-11
申请人： Guohua Li
发明人： Guohua Li
IPC分类号： H01M4/58 , C01B25/37 , C01B25/45 , H01M4/02 , H01M4/52 , H01M4/136 , H01M10/0525 , H01M4/134 , H01M4/40 , H01M4/587
摘要： The invention provides a positive electrode material and a battery using the same which can achieve a higher discharge voltage and which can obtain excellent charge-and-discharge properties, without reducing the capacity. A positive electrode (12) and a negative electrode (14) are configured through a separator (15) in between. The positive electrode (12) contains a compound expressed by a general formula Li1+xMnyFezPO4 (wherein x, y and z are values within ranges of 0
摘要翻译：本发明提供一种正极材料和使用该正极材料的电池，其可以实现更高的放电电压，并且可以在不降低容量的情况下获得优异的充放电特性。正极（12）和负极（14）之间通过隔板（15）构成。正极（12）含有由通式Li1 + xMnyFezPO4表示的化合物（其中x，y和z为0

3. 发明授权

US09054378B2 Positive plate material and cell comprising it 有权
标题翻译：正片材料和包含它的电池
公开(公告)号：US09054378B2
公开(公告)日：2015-06-09
申请号：US10466014
申请日：2002-11-08
申请人： Guohua Li
发明人： Guohua Li
IPC分类号： H01M4/50 , H01M4/52 , H01M4/505 , H01M4/131 , H01M4/525 , H01M10/052
CPC分类号： H01M4/505 , H01M4/131 , H01M4/525 , H01M10/052 , Y02E60/122
摘要： Provided are a cathode material capable of achieving a higher discharge capacity and a higher discharge voltage, and obtaining superior charge-discharge characteristics, and a battery using the cathode material. A separator (15) is disposed between a cathode (12) and an anode (14). The cathode (12) comprises a lithium composite oxide represented by LiaMIbMIIcOd. MI represents at least two kinds selected from the group consisting of Mn, Ni and Co, and MII represents at least one kind selected from the group consisting of Al, Ti, Mg and B. Further, a, b, c and d are within a range satisfying 1.0 b+c, 1.8
摘要翻译：提供能够实现更高放电容量和更高放电电压并获得优异充电 - 放电特性的阴极材料和使用该阴极材料的电池。分离器（15）设置在阴极（12）和阳极（14）之间。阴极（12）包含由LiaMIbMIIcOd表示的锂复合氧化物。 MI表示选自Mn，Ni和Co中的至少两种，MII表示选自Al，Ti，Mg和B中的至少一种。此外，a，b，c和d在满足1.0 b + c，1.8

4. 发明申请

US20120164525A1 LITHIUM SECONDARY BATTERY, POSITIVE ELECTRODE ACTIVE MATERIAL, POSITIVE ELECTRODE, ELECTRIC TOOL, ELECTRIC VEHICLE, AND POWER STORAGE SYSTEM 有权
标题翻译：锂二次电池，正极电极活性材料，正极电极，电动工具，电动车辆和蓄电池系统
公开(公告)号：US20120164525A1
公开(公告)日：2012-06-28
申请号：US13326018
申请日：2011-12-14
申请人： Kazuaki Endoh , Akira Takamuku , Masaharu Senoue , Guohua Li , Kenichi Kawase , Yosuke Hosoya
发明人： Kazuaki Endoh , Akira Takamuku , Masaharu Senoue , Guohua Li , Kenichi Kawase , Yosuke Hosoya
IPC分类号： H01M4/52 , H01M10/056 , H01M4/60
CPC分类号： H01M4/525 , H01M4/131 , H01M4/366 , H01M4/485 , H01M10/0525 , Y02E60/122
摘要： A lithium secondary battery includes a positive electrode, a negative electrode, and an electrolyte solution. The positive electrode contains a positive electrode active material including element M2 incorporated in a crystal structure in a surface layer area of a complex oxide, the oxide including the element M1 and being represented by the following formula (1), M2 being different from M1. The element M2 is at least one kind selected from the group consisting of magnesium Mg, calcium Ca, titanium Ti, zirconium Zr, sulfur S, fluorine F, iron Fe, copper Cu, boron B, aluminum Al, phosphorus P, carbon C, manganese Mn, nickel Ni, and cobalt Co. Li1+a(MnbCocNi1−b−c)1−aM1dO2−e (1) M1 is at least one kind of aluminum, magnesium, zirconium, titanium, barium Ba, boron, silicon Si, and iron, a satisfies 0
摘要翻译：锂二次电池包括正极，负极和电解质溶液。正极含有包含复合氧化物的表层区域中的晶体结构的元素M2的正极活性物质，包含元素M1的氧化物由下式（1）表示，M2与M1不同。元素M2为选自镁镁，钙钙，钛钛，锆Zr，硫S，氟F，铁Fe，铜Cu，硼B，铝Al，磷P，碳C，锰锰，镍镍和钴钴Li1 + a（MnbCocNi1-b-c）1-aM1dO2-e（1）M1是铝，镁，锆，钛，钡Ba，硼，硅Si 和铁，满足0

5. 发明申请

US20090053614A1 NON-AQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERY 有权
标题翻译：非水溶性电解液二次电池
公开(公告)号：US20090053614A1
公开(公告)日：2009-02-26
申请号：US12184861
申请日：2008-08-01
申请人： Minoru Hasegawa , Yuzuru Fukushima , Guohua Li , Takehiko Ishii , Masaki Kuratsuka
发明人： Minoru Hasegawa , Yuzuru Fukushima , Guohua Li , Takehiko Ishii , Masaki Kuratsuka
IPC分类号： H01M10/26 , H01M4/40
CPC分类号： H01M4/5825 , H01M4/38 , H01M4/382 , H01M4/386 , H01M4/387 , H01M4/405 , H01M10/0567 , H01M10/0568
摘要： A non-aqueous electrolytic solution secondary battery includes a positive electrode containing, as a positive electrode active material, a compound represented by the following general formula, LixFe1-yMyPO4, wherein M is at least one member selected from the group consisting of Co, Ni, Cu, Zn, Al, Sn, B, Ga, Cr, V, Ti, Mg, Ca and Sr; 0.9
摘要翻译：非水电解液二次电池包括含有作为正极活性物质的由以下通式表示的化合物LixFe1-yMyPO4的正极，其中M为选自Co，Ni中的至少一种，Cu，Zn，Al，Sn，B，Ga，Cr，V，Ti，Mg，Ca和Sr; 0.9

6. 发明申请

US20070129938A1 METHOD AND APPARATUS FOR TRAINING A PROSODY STATISTIC MODEL AND PROSODY PARSING, METHOD AND SYSTEM FOR TEXT TO SPEECH SYNTHESIS 有权
标题翻译：用于训练突出统计模型和前景分析的方法和装置，用于语音合成的方法和系统
公开(公告)号：US20070129938A1
公开(公告)日：2007-06-07
申请号：US11539434
申请日：2006-10-06
申请人： Haifeng Wang , Guohua Li
发明人： Haifeng Wang , Guohua Li
IPC分类号： G06F17/21
CPC分类号： G06F17/2818
摘要： The present invention provides a method and apparatus for training a prosody statistic model and prosody parsing, a method and system for text to speech synthesis. Said method for training a prosody statistic model with a raw corpus that includes a plurality of sentences with punctuation, comprising: transforming said plurality of sentences in said raw corpus into a plurality of token sequences respectively; counting a frequency for each adjacent token pair occurring in said plurality of token sequences and frequencies of punctuation that represents a pause occurring at associated positions of said each token pair; calculating pause probabilities at said associated positions of said each token pair; and constructing said prosody statistic model based on said token pairs and said pause probabilities at associated positions thereof. With the present invention a prosody statistic model can be trained from a raw corpus without manually prosody parsing tags. And the prosody statistic model can be used in the prosody parsing and further voice synthesis.
摘要翻译：本发明提供了一种用于训练韵律统计模型和韵律解析的方法和装置，一种用于文本到语音合成的方法和系统。用于训练具有包括多个具有标点符号的句子的原始语料库的韵律统计模型的所述方法，包括：分别将所述原始语料库中的所述多个句子变换成多个令牌序列; 计算在所述多个令牌序列中出现的每个相邻令牌对的频率和表示在所述每个令牌对的相关联位置发生的暂停的标点符号的频率; 计算所述每个令牌对的所述关联位置处的暂停概率; 以及基于所述令牌对和在其关联位置处的所述暂停概率构建所述韵律统计模型。利用本发明，可以从原始语料库训练韵律统计模型，而无需手动韵律解析标签。韵律统计模型可用于韵律解析和语音合成。

7. 发明授权

US07217474B2 Positive electrode active material, non-aqueous electrolyte secondary battery and method for producing positive electrode active material 有权
标题翻译：正极活性物质，非水电解质二次电池以及正极活性物质的制造方法
公开(公告)号：US07217474B2
公开(公告)日：2007-05-15
申请号：US11400942
申请日：2006-04-10
申请人： Atsuo Yamada , Guohua Li , Hideto Azuma
发明人： Atsuo Yamada , Guohua Li , Hideto Azuma
IPC分类号： H01M4/58
CPC分类号： H01M10/052 , C01B25/45 , H01M4/136 , H01M4/1397 , H01M4/382 , H01M4/5825
摘要： A non-aqueous electrolyte secondary battery employing a positive electrode active material containing a compound represented by the general formula LixMyPO4, where 0
摘要翻译：一种非水电解质二次电池，其特征在于，使用含有通式为Li x Y PO 4的化合物的正极活性物质，其中， 0

8. 发明授权

US06300013B1 Material for negative electrode and nonaqueous-electrolyte battery incorporating the same 有权
标题翻译：包含其的负极材料和非水电解质电池
公开(公告)号：US06300013B1
公开(公告)日：2001-10-09
申请号：US09549199
申请日：2000-04-13
申请人： Shinichiro Yamada , Takuya Endo , Hiroshi Imoto , Guohua Li , Hiroaki Tanizaki
发明人： Shinichiro Yamada , Takuya Endo , Hiroshi Imoto , Guohua Li , Hiroaki Tanizaki
IPC分类号： H01M458
CPC分类号： H01M4/583 , H01M4/02 , H01M4/13 , H01M4/133 , H01M4/364 , H01M4/38 , H01M4/386 , H01M4/463 , H01M4/58 , H01M10/0525 , H01M2004/021 , H01M2004/027
摘要： A material for a negative electrode capable of preventing change in the volume of an active material occurring when lithium is doped/dedoped to improve resistance against cycle operations. A material for a negative electrode contains a mixture of a non-carbon material and a carbon material, wherein when an assumption is made that the average particle size of the non-carbon material is RM and the average particle size of the carbon material is RC, the ratio RM/RC is not higher than one, and when an assumption is made that the weight of the non-carbon material is WM and the weight of the carbon is WC, the ratio WM/WC is not higher than one or a mixture of a silicon compound and a carbon material, wherein when an assumption is made that the average particle size of the silicon compound is RSi and the average particle size of the carbon material is RC, the ratio RSi/RC is not higher than one.
摘要翻译：能够防止锂掺杂/脱掺杂时发生的活性物质的体积变化的负极材料，以改善对循环操作的抵抗力。负极材料包含非碳材料和碳材料的混合物，其中当假定非碳材料的平均粒径为RM并且碳材料的平均粒径为RC时，RM / RC比不高于1，当假设非碳材料的重量为WM，碳重量为WC时，WM / WC的比例不高于1或硅化合物和碳材料的混合物，其中当假定硅化合物的平均粒径为RSi且碳材料的平均粒径为RC时，RSi / RC比不高于1。

9. 外观设计

USD965748S1 Faucet extender 有权
公开(公告)号：USD965748S1
公开(公告)日：2022-10-04
申请号：US29842082
申请日：2022-06-10
申请人： Guohua Li , Ziru Wang
设计人： Guohua Li , Ziru Wang

10. 发明申请

US20100173197A1 CATHODE ACTIVE MATERIAL, METHOD OF MANUFACTURING THE SAME AND BATTERY 有权
标题翻译：阴极活性材料，其制造方法和电池
公开(公告)号：US20100173197A1
公开(公告)日：2010-07-08
申请号：US11914535
申请日：2006-05-11
申请人： Guohua Li , Nozomu Morita , Tomoyo Ooyama , Kiyohiko Suzuki , Kotaro Satori , Hideto Azuma , Yosuke Hosoya , Koji Morita , Haruo Watanabe
发明人： Guohua Li , Nozomu Morita , Tomoyo Ooyama , Kiyohiko Suzuki , Kotaro Satori , Hideto Azuma , Yosuke Hosoya , Koji Morita , Haruo Watanabe
IPC分类号： H01M4/52 , H01M4/02 , H01M4/88
CPC分类号： H01M4/366 , B05D5/12 , C01G45/1228 , C01G51/42 , C01G51/50 , C01G53/50 , C01P2002/02 , C01P2002/50 , C01P2002/52 , C01P2002/72 , C01P2002/74 , C01P2004/32 , C01P2004/50 , C01P2004/61 , C01P2004/62 , C01P2004/80 , C01P2006/40 , H01M4/0402 , H01M4/131 , H01M4/485 , H01M4/505 , H01M4/525 , H01M4/5825 , H01M10/0525 , Y02E60/122
摘要： A cathode active material capable of obtaining a high capacity and capable of improving stability or low-temperature characteristics, a method of manufacturing the same, and a battery are provided. A cathode (21) includes a cathode active material including a lithium complex oxide including Li and at least one kind selected from the group consisting of Co, Ni and Mn, and P and at least one kind selected from the group consisting of Ni, Co, Mn, Fe, Al, Mg and Zn as coating elements on a surface of the lithium complex oxide. Preferably, the contents of the coating elements are higher on the surface of the cathode active material than those in the interior thereof, and decrease from the surface to the interior.
摘要翻译：提供能够获得高容量并能够提高稳定性或低温特性的阴极活性材料，其制造方法和电池。阴极（21）包括包含Li的锂复合氧化物和选自由Co，Ni和Mn组成的组中的至少一种以及P和选自Ni，Co中的至少一种的正极活性材料，Mn，Fe，Al，Mg和Zn作为锂复合氧化物表面上的涂层元素。优选地，阴极活性材料的表面上的涂层元素的含量高于其内部的含量，并且从表面到内部减少。

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