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    • 3. 发明授权
    • Method for testing peritoneum function and a peritoneal dialysis planning apparatus
    • 腹膜功能检测方法及腹膜透析计划仪
    • US08449496B2
    • 2013-05-28
    • US12470127
    • 2009-05-21
    • Hiroyuki HamadaMasahiro Okamoto
    • Hiroyuki HamadaMasahiro Okamoto
    • A61M1/00
    • A61M1/28
    • The present invention is a peritoneal function testing method characterized by using a ratio MTACun/MTACc calculated using MTACun and MTACc as an index for a peritoneal function test, where MTACun is an overall mass transfer-area coefficient for urea nitrogen and MTACc is an overall mass transfer-area coefficient for creatinine. The use of MTACun/c of the present invention in this way enables examination of the future peritoneal function of a patient (a mechanism of deterioration in peritoneal function). To be specific, MTACun and MTACc can be obtained by computing Pyle-Popovich model. In addition, the peritoneal function testing method may further calculate a permeability coefficient for cell pores (LPSC) and an overall permeability coefficient (LPS) from Three-Pore Theory model while obtaining a ratio LPSC/LPS calculated using the LPSC and the LPS, and may use the LPSC/LPS ratio and the MTACun/MTACc ratio as indexes for the peritoneal function test.
    • 本发明是一种腹膜功能测试方法,其特征在于使用MTACun和MTACc计算的MTACun / MTACc比值作为腹膜功能测试的指标,其中MTACun是尿素氮的总质量传递面积系数,MTACc是总体质量 肌酐转移面积系数。 以这种方式使用本发明的MTACun / c能够检查患者的未来腹膜功能(腹膜功能恶化的机制)。 具体来说,可以通过计算Pyle-Popovich模型来获得MTACun和MTACc。 此外,腹膜功能检查方法还可以在获得使用LPSC和LPS计算的LPSC / LPS比例时,从三孔理论模型进一步计算细胞孔(LPSC)的渗透系数和总渗透系数(LPS),以及 可以使用LPSC / LPS比例和MTACun / MTACc比作为腹膜功能试验的指标。
    • 6. 发明授权
    • Method for testing peritoneum function and a peritoneal dialysis planning apparatus
    • 腹膜功能检测方法及腹膜透析计划仪
    • US07704224B2
    • 2010-04-27
    • US10556394
    • 2004-05-13
    • Hiroyuki HamadaMasahiro Okamoto
    • Hiroyuki HamadaMasahiro Okamoto
    • A61M1/00
    • A61M1/28
    • A peritoneal function testing method of using a ratio MTACun/MTACc calculated using MTACun and MTACc as an index for a peritoneal function test. MTACun is an overall mass transfer-area coefficient for urea nitrogen and MTACc is an overall mass transfer-area coefficient for creatinine. Use of the MTACun/MTACc ratio enables examination of the future peritoneal function of a patient (a mechanism of deterioration in peritoneal function). MTACun and MTACc are obtained using a Pyle-Popovich model. The peritoneal function testing method further calculates a permeability coefficient for cell pores (LPSC) and an overall permeability coefficient (LPS) from a Three-Pore Theory model to obtain a ratio LPSC/LPS calculated using the LPSC and the LPS, and further uses the LPSC/LPS ratio and the MTACun/MTACc ratio as indexes for the peritoneal function test.
    • 使用MTACun和MTACc比值计算的腹膜功能测试方法作为腹膜功能测试的指标。 MTACun是尿素氮的总传质面积系数,MTACc是肌酸酐的总传质面积系数。 使用MTACun / MTACc比可以检查患者未来腹膜功能(腹膜功能恶化的机制)。 使用Pyle-Popovich模型获得MTACun和MTACc。 腹膜功能检测方法从三孔理论模型进一步计算细胞孔(LPSC)的渗透系数和总渗透系数(LPS),以获得使用LPSC和LPS计算的LPSC / LPS比例,并进一步使用 LPSC / LPS比值和MTACun / MTACc比值作为腹膜功能检查指标。
    • 9. 发明申请
    • Method for examination about peritoneal function
    • 腹膜功能检查方法
    • US20050244909A1
    • 2005-11-03
    • US10520330
    • 2003-07-08
    • Hiroyuki HamadaShinji Namoto
    • Hiroyuki HamadaShinji Namoto
    • A61M1/28C12Q1/54G01N33/00
    • A61M1/28A61M2205/70
    • The peritoneal function of a peritoneal dialysis patient is examined to evaluate the condition of the patient. An examining method comprises a step of alternately repeating introduction/drainage of a predetermined quantity of a peritoneal dialyzing fluid of an osmotic pressure and introduction/drainage of a predetermined quantity of another peritoneal dialyzing fluid of an osmotic pressure different from the former one, a step of examining the drain to determine the quantity of peritoneal dialyzing fluid staying in the abdominal cavity of the patient and the concentration of a solute of interest, a step of conducting a peritoneal equilibrium test, and a step of conducting a blood test to grasp the change of the state of the blood caused by the introduction and drainage. The blood test step is executed only once. The current states of the peritoneal dialysis capability and the water removal capability of the patient can be efficiently and accurately evaluated so as to carry out peritoneal dialysis most suitable for the condition of the patient.
    • 检查腹膜透析患者的腹​​膜功能以评估患者的状况。 检查方法包括交替地重复引入/排出预定量的渗透压的腹膜透析液和引入/排出预定量的与前者不同的渗透压的另一个腹膜透析液的步骤,步骤 检查排水口以确定停留在患者腹腔中的腹膜透析液的量和感兴趣溶质的浓度,进行腹膜平衡测试的步骤,以及进行血液测试以掌握变化的步骤 的引进排水造成的血液状况。 血液检测步骤仅执行一次。 可以有效和准确地评估患者的腹膜透析能力和除水能力的现状,以进行最适合患者状况的腹膜透析。