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1. 发明授权

US09326755B2 Biopsy device tissue sample holder with bulk chamber and pathology chamber 有权
标题翻译：活检装置组织样品架具有散装室和病理室
公开(公告)号：US09326755B2
公开(公告)日：2016-05-03
申请号：US13218656
申请日：2011-08-26
申请人： Kevin M. Fiebig , Jessica P. Leimbach , Kyle P. Moore , Andrew P. Nock
发明人： Kevin M. Fiebig , Jessica P. Leimbach , Kyle P. Moore , Andrew P. Nock
IPC分类号： A61B10/00 , A61B10/02
CPC分类号： A61B10/0266 , A61B10/0096 , A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2010/0225
摘要： A biopsy device includes a probe, a holster, and a tissue sample holder for collecting tissue samples. The probe includes a needle and a hollow cutter. The tissue sample holder includes a housing having one or more chambers that are configured to receive a removable tray including one or more prongs and a bulk chamber of a different volume than the one or more chambers. The housing is releasably engageable with the probe. Each tray prong is configured to receive a tissue sample communicated through the cutter lumen. The tray is removable from the housing, such as along an axial direction. The tissue sample holder is rotatable to successively index each chamber to the cutter lumen. The trays may be flexible, resilient, or rigid.
摘要翻译：活检装置包括用于收集组织样本的探针，皮套和组织样本保持器。探针包括针和中空切割器。组织样本保持器包括具有一个或多个腔室的壳体，其被配置为接收包括一个或多个尖头的可移除托盘和与所述一个或多个腔室不同体积的体积室。壳体可释放地与探头接合。每个托盘插脚构造成接收通过切割器内腔连通的组织样本。托盘可以从壳体移除，例如沿轴向移动。组织样本保持器可旋转，以将每个室连续地指向切割器内腔。托盘可以是柔性的，弹性的或刚性的。

2. 发明授权

US08167814B2 Biopsy targeting cube with malleable members 失效
标题翻译：活检针对具有韧性成员的立方体
公开(公告)号：US08167814B2
公开(公告)日：2012-05-01
申请号：US12485168
申请日：2009-06-16
申请人： Jessica P. Leimbach , Eric B. Smith , Rebbeca J. Mollere
发明人： Jessica P. Leimbach , Eric B. Smith , Rebbeca J. Mollere
IPC分类号： A61B10/00 , A61B19/00
CPC分类号： A61B90/17 , A61B10/0266 , A61B90/11 , A61B2017/00796 , A61B2017/00862 , A61B2017/3407 , A61B2017/3411
摘要： A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device comprises a probe and other components, which selectively couple with a targeting cube that is configured to selectively couple with a grid plate having apertures for receiving the targeting cube. The targeting cube comprises a body defined by faces, and guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide passageways through the targeting cube. The body of the targeting cube is at least partially comprised of elastomeric material to allow for adjustment of the orientation of the passageways. The body of the targeting cube is further comprised of malleable members that flank the passageways and allow for angulation of an instrument, such as by maintaining an adjusted orientation of a passageway into which the instrument is inserted.
摘要翻译：活检系统包括控制模块，定位组件，活检装置和靶向立方体。活检装置包括探针和其它组件，其选择性地与定向立方体耦合，所述靶向立方体被配置为选择性地与具有用于接收靶向立方体的孔的格栅板耦合。定向立方体包括由面定义的主体，以及引导孔，其引导并终止于面部并且穿过目标立方体的主体以提供通过目标立方体的通道。靶向立方体的主体至少部分地由弹性体材料组成，以允许调节通道的取向。定向立方体的主体还包括位于通道侧面并且允许器具成角度的可延展构件，例如通过保持仪器被插入其中的通道的调整的取向。

3. 发明申请

US20110218433A1 Biopsy Marker Delivery Device 审中-公开
标题翻译：活检标记输送装置
公开(公告)号：US20110218433A1
公开(公告)日：2011-09-08
申请号：US12787492
申请日：2010-05-26
申请人： Trevor W.V. Speeg , Julie A. Horning , Edward A. Rhad , Jacob S. Gee , Tiffiny K. Aguon , Jessica P. Leimbach
发明人： Trevor W.V. Speeg , Julie A. Horning , Edward A. Rhad , Jacob S. Gee , Tiffiny K. Aguon , Jessica P. Leimbach
IPC分类号： A61B10/02
CPC分类号： A61B10/02
摘要： A biopsy site marker delivery device includes a relatively flexible marker deployer tube having a closed distal end, a push rod slidably disposed within the tube, and at least one marker disposed in the tube. The deployer tube includes a side exit port with an adjacent ramp for transversely dispensing the marker upon distal advancement of the push rod within the tube. An elongate member such as a sleeve is operable to guide and/or stabilize the flexible deployer tube as the tip of the tube is inserted into an access channel such as a channel provided by a cannula or biopsy device. An internal package member is configured to support the marker delivery device and the elongate member, with the elongate member being positioned over the side exit port to prevent the marker from inadvertently exiting the side exit port. The package member may reside in a sterile packaging envelope
摘要翻译：活检部位标记递送装置包括具有封闭远端的相对灵活的标记器展开管，可滑动地设置在管内的推杆和设置在管中的至少一个标记。配置管包括具有相邻斜面的侧出口，用于在推杆远离前进管内横向分配标记。诸如套筒的细长构件可操作以在管的尖端插入诸如由插管或活检装置提供的通道的进入通道中时引导和/或稳定柔性部署管。内部封装构件被配置为支撑标记输送装置和细长构件，其中细长构件定位在侧出口上方，以防止标记物不经意地离开侧出口。包装件可以驻留在无菌包装外壳中

4. 发明申请

US20110208088A1 Needle Tip for Biopsy Device 有权
标题翻译：活检装置的针尖
公开(公告)号：US20110208088A1
公开(公告)日：2011-08-25
申请号：US12711310
申请日：2010-02-24
申请人： Jessica P. Leimbach , Edward A. Rhad
发明人： Jessica P. Leimbach , Edward A. Rhad
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B10/0283 , A61B2010/0208
摘要： A biopsy device includes a body portion, a cannula, a cutter, and a tissue stop having a proximal face. The cannula has a transverse aperture that is defined in part by a proximal edge and a distal edge. The cutter is movable to a distal position to sever tissue protruding through the transverse aperture. A tip at the distal end of the cannula has a sharp edge that extends proximally to a longitudinal position that is proximal to the longitudinal position of the distal edge of the transverse aperture. The sharp edge of the tip extends to a longitudinal position that is proximal to the longitudinal position of the distal cutting edge of the cutter when the cutter is at the distal position. The sharp edge of the tip extends to a longitudinal position that is proximal to the longitudinal position of the proximal face of the tissue stop.
摘要翻译：活检装置包括主体部分，套管，切割器和具有近端面的组织止挡件。套管具有由近侧边缘和远侧边缘部分限定的横向孔。切割器可移动到远侧位置以切断通过横向孔径突出的组织。套管远端的尖端具有向近侧延伸到靠近横向孔的远端边缘的纵向位置的纵向位置的尖锐边缘。当切割器处于远端位置时，尖端的锋利边缘延伸到纵向位置，该纵向位置接近切割器的远端切割边缘的纵向位置。尖端的锋利边缘延伸到靠近组织止挡件的近端面的纵向位置的纵向位置。

5. 发明申请

US20100160811A1 Z-Stop Feature of Targeting Set for MRI Biopsy Device 审中-公开
标题翻译：磁共振成像检测装置目标定位Z停止特征
公开(公告)号：US20100160811A1
公开(公告)日：2010-06-24
申请号：US12337922
申请日：2008-12-18
申请人： Shailendra K. Parihar , Jessica P. Leimbach , Michael R. Ludzack
发明人： Shailendra K. Parihar , Jessica P. Leimbach , Michael R. Ludzack
IPC分类号： A61B10/00
CPC分类号： A61B17/3403 , A61B2017/3411
摘要： A cradle assembly is configured to support a biopsy device. The cradle assembly comprises first support member and a second support member. A biopsy device may be supported by either the first support member or the second support member. A movement restriction member is operable to restrict the longitudinal distance to which a biopsy device may be advanced relative to the cradle assembly. The movement restriction member may comprise a needle mount, a cannula mount, and/or a z-stop. For instance, a z-stop may be positioned to limit the distance to which a cannula mount may be slid along a rail of the cradle. A screw gear may be used to make fine adjustments to the longitudinal position of the z-stop. A needle mount or cannula mount may also include a ratcheting mechanism to restrict proximal motion of the needle mount or cannula mount along a rail of the cradle.
摘要翻译：托架组件被配置成支撑活检装置。托架组件包括第一支撑构件和第二支撑构件。活检装置可以由第一支撑构件或第二支撑构件支撑。运动限制构件可操作以限制活检装置相对于支架组件可前进的纵向距离。移动限制构件可以包括针座，套管座和/或z形止动件。例如，z止动件可以被定位成限制套管安装件沿着支架的轨道滑动的距离。可以使用螺旋齿轮来对z形止动件的纵向位置进行微调。针安装件或套管安装件还可以包括棘轮机构，以限制针座或插管座沿着支架的轨道的近端运动。

6. 发明授权

US08460206B2 Multi-orientation targeting set for MRI biopsy device 失效
标题翻译：用于MRI活检装置的多方位瞄准
公开(公告)号：US08460206B2
公开(公告)日：2013-06-11
申请号：US12337872
申请日：2008-12-18
申请人： Shailendra K. Parihar , Jessica P. Leimbach , Michael R. Ludzack
发明人： Shailendra K. Parihar , Jessica P. Leimbach , Michael R. Ludzack
IPC分类号： A61B10/00
CPC分类号： A61B90/11 , A61B10/0275 , A61B10/0283 , A61B2017/00911 , A61B2017/3409
摘要： A biopsy device targeting set includes a vertical member, a carriage that is vertically movable along the vertical member, and a cradle coupled with the carriage. The cradle has a pair of substantially perpendicular mounting arms. Each mounting arm has a recess that may receive a rail of the carriage, such that the cradle may be mounted to the same rail in different orientations. Each mounting arm also has a biopsy device mounting feature, which may be a recess or a rail. The biopsy device mounting feature is configured to engage with a complementary feature of a biopsy device, such that a biopsy device may be mounted to either mounting arm. A z-stop feature is operable to selectively restrict longitudinal motion along either or both of the biopsy device mounting features. The targeting set may be used with a biopsy device in an MRI environment.
摘要翻译：活检装置瞄准装置包括垂直构件，可沿垂直构件垂直移动的托架和与托架联接的托架。托架具有一对基本垂直的安装臂。每个安装臂具有可以容纳托架的轨道的凹部，使得托架可以以不同的取向安装到相同的轨道。每个安装臂还具有活检装置安装特征，其可以是凹槽或轨道。活检装置安装特征被配置成与活组织检查装置的互补特征接合，使得活检装置可以安装到任一安装臂。 z停止特征可操作以选择性地限制沿活检装置安装特征中的一个或两者的纵向运动。靶向组可以与MRI环境中的活检装置一起使用。

7. 发明授权

US08366635B2 Biopsy probe and targeting set interface 失效
标题翻译：活检探针和靶向设定界面
公开(公告)号：US08366635B2
公开(公告)日：2013-02-05
申请号：US12337757
申请日：2008-12-18
申请人： Shailendra K. Parihar , Jessica P. Leimbach
发明人： Shailendra K. Parihar , Jessica P. Leimbach
IPC分类号： A61B5/00
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B2010/0208 , A61B2010/0225 , A61B2017/00398 , A61B2017/0046 , A61B2090/0801
摘要： A biopsy device comprises a targeting set assembly, a probe assembly, and a holster assembly, which are detachable from one another. The targeting set assembly comprises a needle assembly, which comprises a connecting member. The probe assembly comprises components configured to selectively attach to the connecting member of the needle assembly. In some versions, the connecting member comprises a recess, and the probe assembly comprises a protrusion configured to selectively engage the recess. The protrusion may be provided on a rocking member or on a resilient arm. The rocking member or resilient arm may bias the protrusion to enter the recess. The connection of the probe assembly to needle assembly provides a device for use during a biopsy procedure. The connection of the probe assembly to needle assembly may further permit rotation of the needle assembly for indexing.
摘要翻译：活检装置包括可彼此分离的靶向组装件，探针组件和皮套组件。靶组件包括一个针组件，其包括一连接件。探针组件包括构造成选择性地附接到针组件的连接构件的部件。在一些形式中，连接构件包括凹部，并且探针组件包括被配置为选择性地接合凹部的突起。突起可以设置在摇摆构件上或弹性臂上。摇摆构件或弹性臂可以偏置突起以进入凹部。探针组件与针组件的连接提供了在活检过程中使用的装置。探头组件与针组件的连接可以进一步允许针组件的旋转以进行索引。

8. 发明申请

US20100317991A1 Biopsy Targeting Cube with Elastomeric Body 失效
标题翻译：活检靶向立方体与弹性体
公开(公告)号：US20100317991A1
公开(公告)日：2010-12-16
申请号：US12485138
申请日：2009-06-16
申请人： Jessica P. Leimbach , Rebecca J. Mollere , Eric B. Smith
发明人： Jessica P. Leimbach , Rebecca J. Mollere , Eric B. Smith
IPC分类号： A61B10/02
CPC分类号： A61B90/17 , A61B10/0233 , A61B90/11 , A61B2017/00796 , A61B2017/00862 , A61B2017/3407 , A61B2017/3411
摘要： A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device comprises a holster portion and a probe. The probe and/or other associated components are configured to selectively couple with a targeting cube that is configured to selectively couple with a grid plate having apertures for receiving the targeting cube. The targeting cube comprises a body defined by faces. The targeting cube further comprises guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide a passageway through the targeting cube. The body of the targeting cube is at least partially comprised of elastomeric material to allow for compression of the body. The elastomeric material may thus provide a secure fit with a wide range of grid plates having openings of various shapes and sizes.
摘要翻译：活检系统包括控制模块，定位组件，活检装置和靶向立方体。活检装置包括皮套部分和探针。探针和/或其它相关联的组件被配置为选择性地与定向立方体耦合，所述瞄准立方体被配置为选择性地与具有用于接收目标立方体的孔的格栅板耦合。定向立方体包括由面定义的主体。靶向立方体还包括引导孔，其引导并终止在面部并且穿过定向立方体的主体以提供穿过定向立方体的通道。靶向立方体的主体至少部分地由弹性体材料构成以允许身体的压缩。因此，弹性体材料可以提供具有各种形状和尺寸的开口的宽范围格栅板的安全配合。

9. 发明申请

US20090270760A1 Biopsy Devices 有权
标题翻译：活组织检查装置
公开(公告)号：US20090270760A1
公开(公告)日：2009-10-29
申请号：US12406137
申请日：2009-03-18
申请人： Jessica P. Leimbach , Edward A. Rhad
发明人： Jessica P. Leimbach , Edward A. Rhad
IPC分类号： A61B10/02
CPC分类号： A61B19/54 , A61B6/037 , A61B10/0275 , A61B10/0283 , A61B17/3403 , A61B90/39 , A61B2017/3411 , A61B2090/062 , A61B2090/3904 , A61B2090/3908 , A61B2090/392 , A61B2090/3954
摘要： Biopsy devices and methods useful with Positron Emission Tomography (PET) and Breast Specific Gamma Imaging (BSGI) are disclosed. A biopsy device including a flexible tube having a side aperture, and a PET or BSGI imageable material disposed within the flexible tube is disclosed. A biopsy method is disclosed that includes advancing a flexible tube having a PET or BSGI imageable material distally through the biopsy device. Various other embodiments and applications are disclosed.
摘要翻译：公开了用于正电子发射断层扫描（PET）和乳腺特异性伽玛成像（BSGI）的活检装置和方法。公开了一种包括具有侧孔的柔性管和设置在柔性管内的PET或BSGI可成像材料的活检装置。公开了一种活检方法，其包括通过活检装置向前推进具有PET或BSGI可成像材料的柔性管。公开了各种其他实施例和应用。

10. 发明授权

US08858537B2 Biopsy targeting cube with living hinges 有权
标题翻译：活检针对具有活动铰链的立方体
公开(公告)号：US08858537B2
公开(公告)日：2014-10-14
申请号：US12485318
申请日：2009-06-16
申请人： Jessica P. Leimbach
发明人： Jessica P. Leimbach
IPC分类号： A61B10/02 , A61B17/00 , A61B17/34 , A61B19/00
CPC分类号： A61B17/3403 , A61B5/061 , A61B10/0266 , A61B10/0275 , A61B90/17 , A61B2010/0208 , A61B2017/00796 , A61B2017/00862 , A61B2017/3407 , A61B2017/3411 , A61B2090/374
摘要： A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device comprises a holster portion and a probe. The probe and/or other associated components are configured to selectively couple with a targeting cube, where the targeting cube is configured to selectively couple with a grid plate having apertures for receiving the targeting cube. The targeting cube comprises a body defined by faces. The targeting cube further comprises guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide passageways through the targeting cube. The targeting cube further comprises at least one hinged member positioned along the outer portion of the targeting cube and interfacing with an aperture in the grid plate. The hinged member may provide a tapered profile to the targeting cube and may further comprise an elastomeric portion.
摘要翻译：活检系统包括控制模块，定位组件，活检装置和靶向立方体。活检装置包括皮套部分和探针。探针和/或其它相关联的组件被配置为选择性地与靶向立方体耦合，其中定向立方体被配置为选择性地与具有用于接收靶向立方体的孔的格栅板耦合。定向立方体包括由面定义的主体。靶向立方体还包括引导孔，其引导并终止在面部并且穿过靶向立方体的主体以提供通过靶向立方体的通道。靶向立方体还包括至少一个铰接构件，该铰接构件沿着靶向立方体的外部部分定位并且与网格板中的孔对接。铰链构件可以向目标立方体提供锥形轮廓，并且还可以包括弹性体部分。

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