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1. 发明授权

US08772277B2 Nitrogen-containing heterocyclic compound 有权
标题翻译：含氮杂环化合物
公开(公告)号：US08772277B2
公开(公告)日：2014-07-08
申请号：US13566091
申请日：2012-08-03
申请人： Shigemitsu Matsumoto , Koji Ono , Yusuke Tominari , Taisuke Katoh , Kazuhiro Miwa , Atsushi Hasuoka , Shinichi Imamura
发明人： Shigemitsu Matsumoto , Koji Ono , Yusuke Tominari , Taisuke Katoh , Kazuhiro Miwa , Atsushi Hasuoka , Shinichi Imamura
IPC分类号： A61K31/00 , C07D401/00
CPC分类号： C07D417/14 , C07D417/06 , C07D451/02
摘要： The present invention provides a novel compound having a superior activity as an ERR-α modulator and useful as an agent for the prophylaxis or treatment of ERR-α associated diseases.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
摘要翻译：本发明提供作为ERR-α调节剂具有优异活性的新型化合物，可用作预防或治疗ERR-α相关疾病的药剂。本发明涉及由下式表示的化合物，其中每个符号如说明书中所定义，或其盐。

2. 发明授权

US08511562B2 Layered two-dimensional code, creation method thereof, and read method 有权
标题翻译：分层二维码，其创建方法和读取方法
公开(公告)号：US08511562B2
公开(公告)日：2013-08-20
申请号：US11988885
申请日：2006-04-04
申请人： Tatsuya Onoda , Kazuhiro Miwa
发明人： Tatsuya Onoda , Kazuhiro Miwa
IPC分类号： G06K7/12 , G06K7/00 , G06K19/08
CPC分类号： G06K19/06037 , G06K19/06046 , G06K2019/06225 , Y10T156/10
摘要： The present invention provides a layered two-dimensional code which can be considerably improved in the data capacity thereof without increasing the area thereof by integrating a plurality of two-dimensional codes by a predetermined correlation and expressing it as one two-dimensional code, a method of creating the layered two-dimensional code, and a method of reading the layered two-dimensional code. The layered two-dimensional code is formed as a surface layer by layering a plurality of code layers (for example, code layers 1, 2, and 3) each having information cells (1a′, 1a″, and the like) arranged in a two-dimensional matrix and by integrating the plurality of code layers. An index information code 1c essentially including the information of an RGB value of each code layer is included at one part of the surface layer. When the information cells (1a′ and 1a″) of the code layers 1 and 2 are superposed.
摘要翻译：本发明提供了一种分层二维码，其数据容量可以大大提高，而不增加其面积，通过以预定的相关性整合多个二维码并将其表示为一个二维码，方法创建分层二维码，以及读取分层二维码的方法。分层二维码通过层叠多个代码层（例如，代码层1,2和3）形成为表面层，每个代码层具有布置在其中的信息单元（1a'，1a“等）二维矩阵并且通过对多个代码层进行积分。基本上包含每个代码层的RGB值的信息的索引信息代码1c被包括在表层的一部分。当代码层1和2的信息单元（1a'和1a“）叠加时。

3. 发明申请

US20130072467A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND 有权
标题翻译：含氮的杂环化合物
公开(公告)号：US20130072467A1
公开(公告)日：2013-03-21
申请号：US13566091
申请日：2012-08-03
申请人： Shigemitsu MATSUMOTO , Koji Ono , Yusuke Tominari , Taisuke Katoh , Kazuhiro Miwa , Atsushi Hasuoka , Shinichi Imamura
发明人： Shigemitsu MATSUMOTO , Koji Ono , Yusuke Tominari , Taisuke Katoh , Kazuhiro Miwa , Atsushi Hasuoka , Shinichi Imamura
IPC分类号： C07D417/14 , A61K31/519 , C07D417/06 , C07D513/04 , A61K31/429
CPC分类号： C07D417/14 , C07D417/06 , C07D451/02
摘要： The present invention provides a novel compound having a superior activity as an ERR-α modulator and useful as an agent for the prophylaxis or treatment of ERR-α associated diseases.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
摘要翻译：本发明提供作为ERR-α调节剂具有优异活性的新型化合物，可用作预防或治疗ERR-α相关疾病的药剂。本发明涉及由下式表示的化合物，其中每个符号如说明书中所定义，或其盐。

4. 发明申请

US20120071486A1 THIENOPYRIMIDINE COMPOUNDS AND USE THEREOF 有权
标题翻译：噻吗啉化合物及其用途
公开(公告)号：US20120071486A1
公开(公告)日：2012-03-22
申请号：US13242541
申请日：2011-09-23
申请人： Nobuo Cho , Takashi Imada , Takenori Hitaka , Kazuhiro Miwa , Masami Kusaka , Nobuhiro Suzuki
发明人： Nobuo Cho , Takashi Imada , Takenori Hitaka , Kazuhiro Miwa , Masami Kusaka , Nobuhiro Suzuki
IPC分类号： A61K31/519 , A61P35/04 , A61P13/08 , A61P15/00 , A61P17/10 , A61P15/18 , A61P25/28 , A61P15/08 , A61P1/00 , A61P15/16 , A61P5/24 , A61P35/00 , A61P17/14
CPC分类号： C07D495/04 , A61K31/519
摘要： The present invention provides a compound represented by the formula: wherein R1 is a C1-4 alkyl; R2 is (1) a 5- to 7-membered nitrogen-containing heterocyclic group which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a hydroxy group, (3′) a C1-4 alkyl and (4′) a C1-4 alkoxy, (2) a phenyl which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a C1-4 alkoxy-C1-4 alkyl, (3′) a mono-C1-4 alkyl-carbamoyl-C1-4 alkyl, (4′) a C1-4 alkoxy and (5′) a mono-C1-4 alkylcarbamoyl-C1-4 alkoxy, or the like; R3 is a C1-4 alkyl; R4 is a C1-4 alkoxy, or the like; n is an integer of 1 to 4; or a salt thereof, as a thienopyrimidine compound having gonadotropin-releasing hormone antagonistic activity.
摘要翻译：本发明提供由下式表示的化合物：其中R1是C1-4烷基; R2是（1）可以具有选自（1'）卤素，（2'）羟基，（3'），C 1〜C 6的取代基的5〜7元含氮杂环基， 4烷基和（4'）C 1-4烷氧基，（2）可具有选自（1'）卤素，（2'）C 1-4烷氧基-C 1-4烷基的取代基的苯基，（3'）单-C 1-4烷基 - 氨基甲酰基-C 1-4烷基，（4'）C 1-4烷氧基和（5'）单-C 1-4烷基氨基甲酰基-C 1-4烷氧基等 ; R3是C1-4烷基; R4是C1-4烷氧基等; n为1〜4的整数，或其盐作为具有促性腺激素释放激素拮抗活性的噻吩并嘧啶化合物。

5. 发明授权

US08058280B2 Substituted thieno[2,3-d]pyrimidin-2,4-dione compounds and uses thereof 有权
标题翻译：取代的噻吩并[2,3-d]嘧啶-2,4-二酮化合物及其用途
公开(公告)号：US08058280B2
公开(公告)日：2011-11-15
申请号：US11848939
申请日：2007-08-31
申请人： Nobuo Cho , Takashi Imada , Takenori Hitaka , Kazuhiro Miwa , Masami Kusaka , Nobuhiro Suzuki
发明人： Nobuo Cho , Takashi Imada , Takenori Hitaka , Kazuhiro Miwa , Masami Kusaka , Nobuhiro Suzuki
IPC分类号： C07D495/04 , A61K31/519 , A61P5/06
CPC分类号： C07D495/04 , A61K31/519
摘要： The present invention provides a compound represented by the formula: wherein R1 is a C1-4 alkyl; R2 is (1) a 5- to 7-membered nitrogen-containing heterocyclic group which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a hydroxy group, (3′) a C1-4 alkyl and (4′) a C1-4 alkoxy, (2) a phenyl which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a C1-4 alkoxy-C1-4 alkyl, (3′) a mono-C1-4 alkyl-carbamoyl-C1-4 alkyl, (4′) a C1-4 alkoxy and (5′) a mono-C1-4 alkylcarbamoyl-C1-4 alkoxy, or the like; R3 is a C1-4 alkyl; R4 is a C1-4 alkoxy, or the like; n is an integer of 1 to 4; or a salt thereof, as a thienopyrimidine compound having gonadotropin-releasing hormone antagonistic activity.
摘要翻译：本发明提供由下式表示的化合物：其中R1是C1-4烷基; R2是（1）可以具有选自（1'）卤素，（2'）羟基，（3'），C 1〜C 6的取代基的5〜7元含氮杂环基， 4烷基和（4'）C 1-4烷氧基，（2）可具有选自（1'）卤素，（2'）C 1-4烷氧基-C 1-4烷基的取代基的苯基，（3'）单-C 1-4烷基 - 氨基甲酰基-C 1-4烷基，（4'）C 1-4烷氧基和（5'）单-C 1-4烷基氨基甲酰基-C 1-4烷氧基等 ; R3是C1-4烷基; R4是C1-4烷氧基等; n为1〜4的整数，或其盐作为具有促性腺激素释放激素拮抗活性的噻吩并嘧啶化合物。

6. 发明申请

US20110130861A1 SEMICONDUCTOR MANUFACTURING APPARATUS AND CONTROL SYSTEM AND CONTROL METHOD THEREFOR 失效
标题翻译：半导体制造装置及其控制系统及其控制方法
公开(公告)号：US20110130861A1
公开(公告)日：2011-06-02
申请号：US13020692
申请日：2011-02-03
申请人： Kazuhiro MIWA , Kazuhiro WATANABE , Akito MIFUNE
发明人： Kazuhiro MIWA , Kazuhiro WATANABE , Akito MIFUNE
IPC分类号： G06F19/00
CPC分类号： G05B13/048
摘要： Disclosed herein is technology for, among other things, a semiconductor manufacturing apparatus, and a control system and a control method therefor, by which a target parameter that is measured from a wafer processed with a plurality of processing parameters that are processing conditions of the semiconductor manufacturing apparatus to process a wafer, a multiple classification analysis is performed with the plurality of processing parameters and the target parameter to calculate a model formula expressing the target parameter in a selected parameter, a predicted value of the target parameter of the wafer being processed by use of the model formula is calculated, while the processing is being performed, the processing parameters of the processing is modified on the basis of the predicted value, and the processing is continuously performed.
摘要翻译：本文公开了一种技术，其中包括半导体制造装置，以及控制系统及其控制方法，通过该半导体制造装置，从用作为半导体的处理条件的多个处理参数处理的晶片测量的目标参数用于处理晶片的制造装置，利用多个处理参数和目标参数进行多重分类分析，以计算表示所选参数中的目标参数的模型公式，所述晶片的目标参数的预测值由在进行处理的同时，计算出模型公式的使用，根据该预测值对处理的处理参数进行修正，继续进行处理。

7. 发明申请

US20060160829A1 Thienopyrimidine compounds and use thereof 有权
标题翻译：噻吩并嘧啶化合物及其用途
公开(公告)号：US20060160829A1
公开(公告)日：2006-07-20
申请号：US10544069
申请日：2004-01-28
申请人： Nobuo Cho , Takashi Imada , Takenori Hitaka , Kazuhiro Miwa , Masami Kusaka , Nobuhiro Suzuki
发明人： Nobuo Cho , Takashi Imada , Takenori Hitaka , Kazuhiro Miwa , Masami Kusaka , Nobuhiro Suzuki
IPC分类号： A61K31/55 , A61K31/541 , A61K31/5377 , A61K31/519 , C07D498/02
CPC分类号： C07D495/04 , A61K31/519
摘要： The present invention provides a compound represented by the formula: wherein R1 is a C1-4 alkyl; R2 is (1) a 5- to 7-membered nitrogen-containing heterocyclic group which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a hydroxy group, (3′) a C1-4 alkyl and (4′) a C1-4 alkoxy, (2) a phenyl which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a C1-4 alkoxy-C1-4 alkyl, (3′) a mono-C1-4 alkyl-carbamoyl-C1-4 alkyl, (4′) a C1-4 alkoxy and (5′) a mono-C1-4 alkylcarbamoyl-C1-4 alkoxy, or the like; R3 is a C1-4 alkyl; R4 is a C1-4 alkoxy, or the like; n is an integer of 1 to 4; or a salt thereof, as a thienopyrimidine compound having gonadotropin-releasing hormone antagonistic activity.
摘要翻译：本发明提供由下式表示的化合物：其中R 1是C 1-4烷基; R 2是（1）可以具有选自（1'）卤素，（2'）羟基的取代基的5-至7-元含氮杂环基，（3'）C 1-4烷基和（4'）C 1-4烷氧基，（2）可以具有选自以下的取代基的苯基：（1'）卤素，（2'），C 1-4烷氧基-C 1-4烷基，（3'）单-C 烷基 - 氨基甲酰基-C 1-4烷基，（4'）C 1-4烷氧基和（5'）单 -C 1-4烷基氨基甲酰基-C 1-4烷氧基等; R 3是C 1-4烷基; R 4是C 1-4烷氧基等; n为1〜4的整数，或其盐作为具有促性腺激素释放激素拮抗活性的噻吩并嘧啶化合物。

8. 发明授权

US07569570B2 Thienopyrimidines, process for preparing the same and use thereof 有权
标题翻译：噻吩并嘧啶，其制备方法及其用途
公开(公告)号：US07569570B2
公开(公告)日：2009-08-04
申请号：US10502903
申请日：2003-01-29
申请人： Shuichi Furuya , Takashi Imada , Takenori Hitaka , Kazuhiro Miwa , Masami Kusaka , Nobuhiro Suzuki
发明人： Shuichi Furuya , Takashi Imada , Takenori Hitaka , Kazuhiro Miwa , Masami Kusaka , Nobuhiro Suzuki
IPC分类号： A61K31/519 , C07D495/04
CPC分类号： C07D495/04
摘要： The present invention provides a thienopyrimidine compound, represented by the formula [wherein, R1 is C1-4 alkyl, R2 is (1) phenyl optionally having a substituent such as amino, mono C1-4 alkylamino and di C1-4 alkylamino, or (2) a heterocyclic group optionally having a substituent such as amino, mono C1-4 alkylamino and di C1-4 alkylamino and the like, R3 is a hydrogen atom or C1-4 alkyl, R4 is C1-4 alkyl optionally having a substituent such as C1-4 alkoxy-carbonyl, carboxyl, mono C1-4 alkylamino and N—C1-4 alkyl-N—C7-10 aralkylamino and the like] or a salt thereof, which has antagonistic action for gonadotropin-releasing hormone.
摘要翻译：本发明提供由式[其中，R 1为C 1-4烷基，R 2为（1）任选具有取代基的苯基，例如氨基，单C 1-4烷基氨基和二C 1-4烷基氨基的噻吩并嘧啶化合物或（ 2）任选具有取代基的杂环基，例如氨基，单C 1-4烷基氨基和二C 1-4烷基氨基等，R 3是氢原子或C 1-4烷基，R 4是任选具有取代基的C 1-4烷基作为对促性腺激素释放激素具有拮抗作用的C 1-4烷氧基 - 羰基，羧基，单C 1-4烷基氨基和N-C 1-4烷基-N C 7-10芳烷基氨基等]或其盐。

9. 发明授权

US08418932B2 Wheel guard apparatus 有权
标题翻译：车轮防护装置
公开(公告)号：US08418932B2
公开(公告)日：2013-04-16
申请号：US12745243
申请日：2008-11-28
申请人： Masaki Seki , Kazuhiro Miwa , Tomomi Funada , Hironari Muramatsu , Takaaki Irie , Yoshio Morikawa , Katsunari Konishi , Tetsuya Hanazaki
发明人： Masaki Seki , Kazuhiro Miwa , Tomomi Funada , Hironari Muramatsu , Takaaki Irie , Yoshio Morikawa , Katsunari Konishi , Tetsuya Hanazaki
IPC分类号： E01B5/18
CPC分类号： E01B5/18
摘要： A wheel guard apparatus capable of preventing a wheel from derailing and preventing a vehicle from seriously deviating from a track even if the wheel has derailed includes a fixed portion fixed to a railroad tie located between main line rails; a movable portion supported by a rotating shaft provided on the fixed portion and extending in a horizontal direction and configured to be rotatable around the rotating shaft toward a track center side; and a guard rail located at a position separated from the rotating shaft of the movable portion and held to extend in parallel with the main line rail. The guard rail includes an outer stopper portion configured to prevent the wheel from derailing toward an inner side of the main line rail and an inner stopper portion configured to prevent a derailed vehicle from deviating to an outer side of a track.
摘要翻译：即使车轮脱轨，也能够防止车轮脱轨并防止车辆严重偏离轨道的车轮防护装置包括固定在位于主线轨道之间的铁路连接线的固定部分; 可动部，其由设置在所述固定部上的旋转轴支撑，并且在水平方向上延伸并且能够围绕所述旋转轴向轨道中心侧旋转; 以及位于与可动部的旋转轴分离的位置并与主线轨道平行地延伸的保护轨道。保护轨包括：外止动部，其构造成防止车轮朝向主线轨道的内侧脱轨;以及内止挡部，其构造成防止脱轨车辆偏离轨道的外侧。

10. 发明申请

US20100216788A1 FUSED HETEROCYCLIC COMPOUND 审中-公开
标题翻译：熔融杂环化合物
公开(公告)号：US20100216788A1
公开(公告)日：2010-08-26
申请号：US12095543
申请日：2006-12-01
申请人： Tomoyasu Ishikawa , Kazuhiro Miwa , Masaki Seto , Hiroshi Banno , Youichi Kawakita
发明人： Tomoyasu Ishikawa , Kazuhiro Miwa , Masaki Seto , Hiroshi Banno , Youichi Kawakita
IPC分类号： A61K31/5377 , C07D487/04 , A61K31/519 , C07D413/14 , A61P35/00
CPC分类号： C07D487/04
摘要： The present invention provides a compound represented by the formula: wherein R1a is a hydrogen atom, R2a is a C1-6 alkyl group substituted by a group represented by —NR6a—CO—(CH2)n—SO2— optionally halogenated C1-4 alkyl wherein n is an integer of 1 to 4, R6a is a hydrogen atom or a C1-4 alkyl group, and —(CH2)n— is optionally substituted by C1-4 alkyl, R3a is a hydrogen atom or a C1-6 alkyl group, R4a is a halogen atom or a C1-6 alkyl group, R5a is a halogen atom or a C1-6 alkyl group, and Xa is a hydrogen atom or a halogen atom, or a salt thereof. The compound of the present invention has a superior tyrosine kinase inhibitory action, is highly safe, and is sufficiently satisfactory as a pharmaceutical product.
摘要翻译：本发明提供由下式表示的化合物：其中R1a是氢原子，R2a是被-NR6a-CO-（CH2）n-SO2-代表的基团取代的C1-6烷基，任选被卤代的C 1-4烷基其中n为1〜4的整数，R6a为氢原子或C1-4烷基， - （CH2）n-为C1-4烷基，R3a为氢原子或C1-6烷基基团，R 4a是卤素原子或C 1-6烷基，R 5a是卤素原子或C 1-6烷基，X a是氢原子或卤素原子或其盐。本发明的化合物具有优异的酪氨酸激酶抑制作用，是高度安全的，并且作为药物产品足够令人满意。

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