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1. 发明授权

US08548592B2 Ultrasonic transducer for a metallic cavity implanted medical device 有权
标题翻译：用于金属腔植入医疗器械的超声换能器
公开(公告)号：US08548592B2
公开(公告)日：2013-10-01
申请号：US13082954
申请日：2011-04-08
申请人： Bin Mi , Abhijeet V. Chavan , Keith R. Maile
发明人： Bin Mi , Abhijeet V. Chavan , Keith R. Maile
IPC分类号： A61N1/375
CPC分类号： A61N1/37288 , A61B5/0028 , A61N1/37217
摘要： Implantable medical devices including an ultrasonic transducer and methods of optimizing an ultrasonic transducer of an implantable medical device are disclosed. The implantable medical device can include a housing, an ultrasonic transducer disposed within an interior of the housing, and a limiting structure configured to constrain deformation of the ultrasonic transducer. The limiting structure can include a separate structure coupled to the housing, or can comprise a resonant portion of the housing itself. During operation, the ultrasonic transducer is configured to communicate at a frequency at or near a resonant frequency of the housing.
摘要翻译：公开了包括超声换能器和优化可植入医疗装置的超声换能器的方法的可植入医疗装置。可植入医疗装置可以包括壳体，设置在壳体内部的超声波换能器以及限制超声换能器变形的限制结构。限制结构可以包括耦合到壳体的单独结构，或者可以包括壳体本身的谐振部分。在操作期间，超声波换能器被配置为在壳体的谐振频率处或接近谐振频率处的频率进行通信。

2. 发明申请

US20130110192A1 MULT-ELEMENT ACOUSTIC RECHARGING SYSTEM 审中-公开
标题翻译： MULT-ELEMENT ACOUSTIC RECHARGGING SYSTEM
公开(公告)号：US20130110192A1
公开(公告)日：2013-05-02
申请号：US13725405
申请日：2012-12-21
申请人： Binh C. Tran , Bin Mi , Robert S. Harguth , Keith R. Maile
发明人： Binh C. Tran , Bin Mi , Robert S. Harguth , Keith R. Maile
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , A61N1/37217
摘要： An acoustic energy delivery system for delivering acoustic energy to an implantable medical device (“IMD”). The system includes an IMD having a power source and an energy delivery device. The energy delivery device includes a controller and an array of ultrasonic elements electrically coupled to the controller and configured to deliver acoustic energy to the IMD. Methods of delivering acoustic energy to an IMD are also disclosed.
摘要翻译：用于将声能递送到可植入医疗装置（“IMD”）的声能递送系统。该系统包括具有电源和能量输送装置的IMD。能量输送装置包括控制器和电耦合到控制器并被配置为向IMD传送声能的超声波元件阵列。还公开了向IMD传递声能的方法。

3. 发明授权

US08433419B2 Method and apparatus for controlling neurostimulation according to physical state 有权
公开(公告)号：US08433419B2
公开(公告)日：2013-04-30
申请号：US13272786
申请日：2011-10-13
申请人： Abhi V. Chavan , Keith R. Maile , David J. Ternes , Juan Gabriel Hincapie Ordonez , Stephen Ruble , Jason J. Hamann
发明人： Abhi V. Chavan , Keith R. Maile , David J. Ternes , Juan Gabriel Hincapie Ordonez , Stephen Ruble , Jason J. Hamann
IPC分类号： A61N1/00
CPC分类号： A61N1/36139 , A61N1/36053 , A61N1/36135
摘要： A neurostimulation system senses a signal indicative of a patient's physical state such as posture and/or activity level. In various embodiments, a stored value for each of stimulation parameters controlling delivery of neurostimulation is selected according to the patient's physical state. In various embodiments, values of the stimulation parameters are approximately optimized for each of a number of different physical states, and are stored for later selection.

4. 发明授权

US08428713B2 Implantable defibrillation output circuit 有权
标题翻译：可植入除颤输出电路
公开(公告)号：US08428713B2
公开(公告)日：2013-04-23
申请号：US13041970
申请日：2011-03-07
申请人： Keith R. Maile , William J. Linder
发明人： Keith R. Maile , William J. Linder
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3912
摘要： An implantable defibrillation circuit can include an output circuit. The output circuit can include a first switch configured to controllably connect a first supply node to a first output node, a second switch configured to controllably connect a second supply node to the first output node through a first rectifier, and the second switch can be configured to inhibit the first switch from connecting the first supply node to the first output node when the second supply node is connected to the first output node through the second switch. In an example, the first and second switches can include insulated gate bipolar transistors.
摘要翻译：可植入除颤电路可以包括输出电路。输出电路可以包括被配置为将第一供应节点可控地连接到第一输出节点的第一开关，被配置为通过第一整流器可控地将第二供电节点连接到第一输出节点的第二开关，并且第二开关可被配置当所述第二供应节点通过所述第二开关连接到所述第一输出节点时，禁止所述第一开关连接所述第一供应节点与所述第一输出节点。在一个示例中，第一和第二开关可以包括绝缘栅双极晶体管。

5. 发明授权

US08311627B2 Method and apparatus for a small power source for an implantable device 有权
标题翻译：用于可植入装置的小型电源的方法和装置
公开(公告)号：US08311627B2
公开(公告)日：2012-11-13
申请号：US12966444
申请日：2010-12-13
申请人： Michael J. Root , Nick A. Youker , Keith R. Maile
发明人： Michael J. Root , Nick A. Youker , Keith R. Maile
IPC分类号： A61N1/00
CPC分类号： A61N1/3787 , A61B5/02 , A61B2562/0217 , A61N1/3752 , A61N1/378 , H01M2/1055 , H01M6/08 , H01M10/0422 , H01M10/0436 , H05K13/00 , Y10T29/49108 , Y10T29/4911
摘要： One example includes a battery that includes a stack of at least one substantially planar anode and at least one substantially planar cathode, wherein the stack defines a contoured exterior, and a battery housing enclosing the stack, the battery housing defining a battery housing exterior, wherein the contoured exterior of the stack is shaped to conform to a contoured interior of the battery housing that approximately conforms to the battery housing exterior, the battery produced by the process of modeling, using fluid dynamics, an exterior of a biocompatible housing and shaping the battery housing to conform to at least some of the exterior of the biocompatible housing.
摘要翻译：一个示例包括电池，其包括至少一个基本上平面的阳极和至少一个基本上平面的阴极的堆叠，其中堆叠限定轮廓外部，以及包围堆叠的电池壳体，电池壳体限定电池壳体外部，其中堆叠的轮廓外形被成形为符合电池壳体的轮廓内部，其大致符合电池壳体外部，通过使用流体动力学，生物相容性壳体的外部和塑造电池的建模过程产生的电池壳体以符合生物相容性壳体的至少一些外部。

6. 发明申请

US20120191155A1 POSTURE SENSOR AUTOMATIC CALIBRATION 有权
标题翻译：自动传感器自动校准
公开(公告)号：US20120191155A1
公开(公告)日：2012-07-26
申请号：US13437374
申请日：2012-04-02
申请人： John D. Hatlestad , Aaron Lewicke , Keith R. Maile
发明人： John D. Hatlestad , Aaron Lewicke , Keith R. Maile
IPC分类号： A61N1/365 , G06F19/00 , G01P21/00
CPC分类号： G01P21/00 , A61B5/0031 , A61B5/103 , A61B5/1038 , A61B5/1116 , A61B5/686 , A61B2560/0223 , A61B2562/0219 , G01C22/00 , G01C25/00 , G01D18/00 , G01P13/00 , G06F17/40 , G06F19/00
摘要： A system and method automatically calibrate a posture sensor, such as by detecting a walking state or a posture change. For example, a three-axis accelerometer can be used to detect a patient's activity or posture. This information can be used to automatically calibrate subsequent posture or acceleration data.
摘要翻译：系统和方法通过检测步行状态或姿势变化来自动校准姿势传感器。例如，可以使用三轴加速度计来检测患者的活动或姿势。该信息可用于自动校准后续姿势或加速度数据。

7. 发明授权

US08060204B2 Low power digital design for deep submicron technology 失效
标题翻译：低功耗数字设计深亚微米技术
公开(公告)号：US08060204B2
公开(公告)日：2011-11-15
申请号：US12394693
申请日：2009-02-27
申请人： Paul Huelskamp , Douglas J. Gifford , Scott A. Reedstrom , Keith R. Maile
发明人： Paul Huelskamp , Douglas J. Gifford , Scott A. Reedstrom , Keith R. Maile
IPC分类号： A61N1/00
CPC分类号： A61N1/3931 , A61N1/37
摘要： An apparatus comprises an implantable medical device that includes a storage circuit. The storage circuit includes a first stage circuit configured to receive an input signal and to invert and store information about a data bit received in the input signal, a second stage circuit coupled to the output of the first stage circuit to invert and store information about a data bit received from the first stage circuit, and an error circuit coupled to the output of the first stage circuit and an output of the second stage circuit. The error circuit generates an error indication when the storage circuit outputs match while the first stage circuit and the second stage circuit are in an inactive state.
摘要翻译：一种装置包括可植入医疗装置，其包括存储电路。存储电路包括：第一级电路，被配置为接收输入信号并反相并存储关于在输入信号中接收的数据位的信息;第二级电路，耦合到第一级电路的输出，以反转和存储关于从第一级电路接收的数据位，以及耦合到第一级电路的输出和第二级电路的输出的误差电路。当第一级电路和第二级电路处于非活动状态时，当存储电路输出匹配时，误差电路产生错误指示。

8. 发明申请

US20110276103A1 OUTPUT CIRCUIT FOR BOTH CARDIAC CONTRACTILE ELECTROSTIMULATION AND NON-CONTRACTILE NEURAL MODULATION 有权
标题翻译：输出电路用于两种心脏电生理电生理和非承压神经调节
公开(公告)号：US20110276103A1
公开(公告)日：2011-11-10
申请号：US13099546
申请日：2011-05-03
申请人： Keith R. Maile , Ramprasad Vijayagopal , Nicholas J. Stessman , Firmin Musungu
发明人： Keith R. Maile , Ramprasad Vijayagopal , Nicholas J. Stessman , Firmin Musungu
IPC分类号： A61N1/362
CPC分类号： A61N1/362 , A61N1/36057 , A61N1/36114 , A61N1/36117 , A61N1/36125
摘要： An apparatus comprises an electrostimulation energy storage capacitor, a circuit path that provides pacing stimulation from the capacitor through the load, a constant current neural stimulation circuit that is switchable into the circuit path to provide neural stimulation through the load and switchable out of the circuit path to provide the pacing stimulation through the load, and a control circuit configured to selectively enable delivery of the pacing stimulation or the constant current neural stimulation.
摘要翻译：一种装置包括电刺激能量存储电容器，电路通过负载从电容器提供起搏刺激的恒定电流神经刺激电路，其可切换到电路路径中以通过负载提供神经刺激并且可从电路路径切换以通过负载提供起搏刺激，以及控制电路，其被配置为选择性地实现起搏刺激或恒定电流神经刺激的传递。

9. 发明授权

US08053740B2 Method and apparatus for radiation effects detection 失效
标题翻译：辐射效应检测方法和装置
公开(公告)号：US08053740B2
公开(公告)日：2011-11-08
申请号：US13044003
申请日：2011-03-09
申请人： Jeffrey E. Stahmann , William J. Linder , Scott R. Stubbs , Keith R. Maile
发明人： Jeffrey E. Stahmann , William J. Linder , Scott R. Stubbs , Keith R. Maile
IPC分类号： G01T1/00
CPC分类号： A61N1/37 , A61N1/3718
摘要： An implantable medical apparatus comprises a solid state electronic circuit, an ionizing radiation exposure sensor, an ionizing radiation dose rate sensor, and a controller circuit. The ionizing radiation exposure sensor is configured to detect an exposure of the solid state electronic circuit to ionizing radiation, and generate an indication of a non-single-event-upset (non-SEU) effect to the solid state electronic circuit from the exposure to ionizing radiation, wherein the sensor comprises an accumulated ionizing radiation exposure sensor. The controller circuit is configured to blank the indication from the accumulated ionizing radiation exposure sensor when the radiation dose rate sensor indicates that flux ionizing radiation exceeds a flux ionizing radiation threshold.
摘要翻译：一种可植入医疗装置，包括固态电子电路，电离辐射曝光传感器，电离辐射剂量率传感器和控制器电路。电离辐射曝光传感器被配置为检测固态电子电路对电离辐射的曝光，并且产生对固态电子电路的非单事件不适（非SEU）效应的指示，从曝光到电离辐射，其中所述传感器包括累积的电离辐射曝光传感器。控制器电路被配置为当辐射剂量率传感器指示通量电离辐射超过通量电离辐射阈值时，从累积的电离辐射曝光传感器中消除指示。

10. 发明授权

US08012098B2 Determining a patient's posture from mechanical vibrations of the heart 有权
标题翻译：从心脏的机械振动确定患者的姿势
公开(公告)号：US08012098B2
公开(公告)日：2011-09-06
申请号：US12484108
申请日：2009-06-12
申请人： Keith R. Maile , Krzysztof Z. Siejko
发明人： Keith R. Maile , Krzysztof Z. Siejko
IPC分类号： A61B5/02
CPC分类号： A61N1/36542 , A61B7/00 , A61N1/36535 , A61N1/36578
摘要： A system for determining a patient's posture by monitoring heart sounds. The system comprises an implantable medical device that includes a sensor operable to produce an electrical signal representative of heart sounds, a sensor interface circuit coupled to the sensor to produce a heart sound signal, and a controller circuit coupled to the sensor interface circuit. The heart sounds are associated with mechanical activity of a patient's heart and the controller circuit is operable to detect a posture of the patient from a heart sound signal.
摘要翻译：通过监测心脏声音来确定患者姿势的系统。该系统包括可植入医疗装置，其包括可操作以产生表示心脏声音的电信号的传感器，耦合到传感器以产生心音信号的传感器接口电路，以及耦合到传感器接口电路的控制器电路。心脏声音与患者心脏的机械活动相关联，并且控制器电路可操作以从心脏声音信号检测患者的姿势。

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