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1. 发明授权

US09060952B2 Synergistic preservative blends 有权
标题翻译：协同防腐剂混合
公开(公告)号：US09060952B2
公开(公告)日：2015-06-23
申请号：US12996044
申请日：2009-05-20
申请人： Rosita Nunez , Larry Kent Hall , Crystal Maira , Joseph Kimler , Craig Carter
发明人： Rosita Nunez , Larry Kent Hall , Crystal Maira , Joseph Kimler , Craig Carter
IPC分类号： A61K8/34 , A61K8/36 , A61K8/49 , A61Q19/00
CPC分类号： A61K8/49 , A61K8/342 , A61K8/345 , A61K8/36 , A61K8/4926 , A61K8/498 , A61K2800/524 , A61Q19/00
摘要： The present invention is a preservative formulation which includes a combination of at least two (2) compounds having bactericidal and/or fungicidal properties wherein the at least two (2) compounds is selected from the group consisting of methylisothiazolinone/piroctone olamine; caprylyl glycol/dehydroacetic acid; undecanol/dehydroacetic acid and lauryl alcohol/sorbic acid. The invention also includes preparations including such combination as well as a method of using the combination to reduce bacterial and fungal load of preparations.
摘要翻译：本发明是一种防腐剂制剂，其包含具有杀菌和/或杀真菌性质的至少两种（2）化合物的组合，其中至少两种（2）化合物选自甲基异噻唑啉酮/吡罗酮醇胺; 癸二醇/脱氢乙酸; 十一烷醇/脱氢乙酸和月桂醇/山梨酸。本发明还包括包括这种组合的制剂以及使用该组合以减少制剂的细菌和真菌负荷的方法。

2. 发明申请

US20110301206A1 SYNERGISTIC PRESERVATIVE BLENDS 有权
标题翻译：协调性防腐剂
公开(公告)号：US20110301206A1
公开(公告)日：2011-12-08
申请号：US12996044
申请日：2009-05-20
申请人： Rosita Nunez , Larry Kent Hall , Crystal Maira , Joseph Kimler , Craig Carter
发明人： Rosita Nunez , Larry Kent Hall , Crystal Maira , Joseph Kimler , Craig Carter
IPC分类号： A01N43/40 , A01P3/00 , A01P1/00 , A01N43/16 , A01N37/06
CPC分类号： A61K8/49 , A61K8/342 , A61K8/345 , A61K8/36 , A61K8/4926 , A61K8/498 , A61K2800/524 , A61Q19/00
摘要： The present invention is a preservative formulation which includes a combination of at least two (2) compounds having bactericidal and/or fungicidal properties wherein the at least two (2) compounds is selected from the group consisting of methylisothiazolinone/piroctone olamine; caprylyl glycol/dehydroacetic acid; undecanol/dehydroacetic acid and lauryl alcohol/sorbic acid. The invention also includes preparations including such combination as well as a method of using the combination to reduce bacterial and fungal load of preparations.
摘要翻译：本发明是一种防腐剂制剂，其包含具有杀菌和/或杀真菌性质的至少两种（2）化合物的组合，其中至少两种（2）化合物选自甲基异噻唑啉酮/吡罗酮醇胺; 癸二醇/脱氢乙酸; 十一烷醇/脱氢乙酸和月桂醇/山梨酸。本发明还包括包括这种组合的制剂以及使用该组合以减少制剂的细菌和真菌负荷的方法。

3. 发明申请

US20090203812A1 Salts of Dehydroacetic Acid as an Antimicrobial for Plastics 审中-公开
标题翻译：脱氢乙酸作为塑料抗菌剂的盐
公开(公告)号：US20090203812A1
公开(公告)日：2009-08-13
申请号：US12370292
申请日：2009-02-12
申请人： Lei Rao , Joe Kimler , Larry Kent Hall
发明人： Lei Rao , Joe Kimler , Larry Kent Hall
IPC分类号： C08K5/09
CPC分类号： C08K5/098 , C08K5/0058
摘要： A plastic material having an antimicrobial characteristic and the method for making the plastic material is provided. The method includes blending and/or extruding a polymeric composition in a process which includes a temperature of at least about 170° C. The method also includes adding an antimicrobial component to the polymeric composition prior to or during the blending and/or extruding. The antimicrobial component includes a salt of a dehydroacetic acid (DHA) in an amount sufficient to provide the resulting plastic material with an effective antimicrobial characteristic. The antimicrobial component including a salt of DHA is stable at temperatures required for processing polymeric compositions.
摘要翻译：提供具有抗菌特性的塑料材料和制造塑料材料的方法。该方法包括在包括至少约170℃的温度的方法中共混和/或挤出聚合物组合物。该方法还包括在混合和/或挤出之前或期间向聚合物组合物中加入抗微生物组分。抗微生物组分包括脱氢乙酸（DHA）的盐，其量足以提供所得塑料材料具有有效的抗微生物特性。包含DHA盐的抗微生物组分在加工聚合物组合物所需的温度下是稳定的。

4. 发明申请

US20110076387A1 METHOD FOR IMPARTING ANTIBIOTIC ACTIVITY TO THE SURFACE OF A SOLID SUBSTRATE 审中-公开
标题翻译：将抗生素活性转移到固体基底表面的方法
公开(公告)号：US20110076387A1
公开(公告)日：2011-03-31
申请号：US12569564
申请日：2009-09-29
申请人： David Joseph Koehl , Joseph Kimler , Larry Kent Hall , Philip Gerdon Sweeny
发明人： David Joseph Koehl , Joseph Kimler , Larry Kent Hall , Philip Gerdon Sweeny
IPC分类号： B05D3/02 , B05D3/06
CPC分类号： A01N25/10 , A61L15/46 , A61L2300/208 , A61L2300/406 , A01N33/12 , A01N37/44
摘要： The present invention relates to a method for imparting antibiotic activity to a surface of a solid substrate by exposing a solid substrate composition to conditions suitable for covalent grafting and thermal polymerization of the substrate.
摘要翻译：本发明涉及一种通过将固体底物组合物暴露于适合共价接枝和基底热聚合的条件来赋予固体基质表面的抗生素活性的方法。

5. 发明申请

US20090203645A1 Broad Spectrum Disinfecting and Sterilizing Composition 审中-公开
标题翻译：广谱消毒灭菌成分
公开(公告)号：US20090203645A1
公开(公告)日：2009-08-13
申请号：US12367592
申请日：2009-02-09
申请人： Larry Kent Hall , Joseph Kimler
发明人： Larry Kent Hall , Joseph Kimler
IPC分类号： A01N33/12 , A01P1/00
CPC分类号： A01N33/12 , A01N35/04 , A01N2300/00
摘要： The present invention relates to antimicrobial compositions including an aromatic dialdehyde and a quaternary ammonium compound wherein the aromatic dialdehyde is orthophthalaldehyde, isophthalaldehyde, terephthalaldehyde, or combinations thereof, and the ratio of aromatic dialdehyde to quaternary ammonium compound is from about 10:1 to about 1:5. The invention also relates to methods of treating surfaces using the antimicrobial compositions of the invention.
摘要翻译：本发明涉及包括芳族二醛和季铵化合物的抗微生物组合物，其中芳族二醛是邻苯二甲醛，间苯二甲醛，对苯二醛或其组合，芳族二醛与季铵化合物的比例为约10:1至约1 ：5。本发明还涉及使用本发明的抗微生物组合物处理表面的方法。

6. 发明授权

US09034943B2 Salts of dehydroacetic acid as a pyrithione stabilizer in plastics 有权
标题翻译：脱氢乙酸作为塑料中吡啶硫酮稳定剂的盐
公开(公告)号：US09034943B2
公开(公告)日：2015-05-19
申请号：US13258874
申请日：2010-03-26
申请人： Larry Kent Hall , Joseph Kimler , Lei Rao
发明人： Larry Kent Hall , Joseph Kimler , Lei Rao
IPC分类号： A01N43/40 , A01N25/22
CPC分类号： A01N43/40 , A01N25/22 , A01N2300/00
摘要： The invention provides a method for preventing discoloration of pyrithione-containing materials, in particular plastic materials or other material such as paints, coatings, adhesives or textiles which are exposed to an outdoor environment. The method is likewise suited for preventing discoloration of other pyrithione-containing materials such as personal care compositions like shampoos. A discoloration inhibitor that includes dehydroacetic acid or a salt thereof is added to the pyrithione-containing material. The discoloration is prevented without the addition of a cyclic organic phosphoric acid ester or an organic phosphite. Use of the discoloration inhibitor does not interfere with the antimicrobial effect of the pyrithione.
摘要翻译：本发明提供了防止含吡啶硫酮的材料，特别是塑料材料或暴露于户外环境的其它材料如油漆，涂料，粘合剂或纺织品的变色的方法。该方法同样适用于防止其它含吡啶硫酮的材料如洗发剂等个人护理组合物变色。将含有脱氢乙酸或其盐的变色抑制剂加入含吡啶硫酮的材料中。防止变色，而不加入环状有机磷酸酯或有机亚磷酸酯。使用变色抑制剂不会影响吡啶硫酮的抗微生物作用。

7. 发明授权

US06583181B1 Antimicrobial quaternary ammonium compositions with reduced ocular irritation 失效
标题翻译：减少眼睛刺激的抗微生物季铵组合物
公开(公告)号：US06583181B1
公开(公告)日：2003-06-24
申请号：US09721523
申请日：2000-11-22
申请人： Michael Yao-Chi Chiang , Larry Kent Hall
发明人： Michael Yao-Chi Chiang , Larry Kent Hall
IPC分类号： A61K3114
CPC分类号： A61K31/195 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K33/00 , A61K33/02 , A01N37/44 , A01N25/32 , A01N2300/00 , A61K2300/00
摘要： The present inventors have discovered that electrolytes, such as the tetrasodium salt of ethylenediaminetetraacetic acid (EDTA), reduce the ocular irritation and increase the disinfecting and sanitizing efficacy of compositions containing quaternary ammonium compounds and/or amines. As a result, concentrated solutions containing quaternary ammonium compounds and/or amines of the present invention have low, if any, ocular irritation. Furthermore, use dilutions of the concentrated solutions of the present invention include ingredients which are approved by the U.S. EPA for use on indirect food contact surfaces, unlike disinfecting and sanitizing compositions containing imidazoline compounds. Additionally, the use dilutions exhibit superior efficacy against gram negative and positive bacteria compared to similar compositions which do not contain the electrolyte and remain effective in hard water. The present invention is a concentrate, such as a sanitizing and disinfecting concentrate, comprising from about 0.5 to about 4.0% by weight of a quaternary ammonium compound, an amine, or a combination thereof and from about 2.0 to about 15.0% by weight of electrolyte, based upon 100% total weight of concentrate. The concentrate is generally substantially free of imidazoline compounds. Another embodiment is an ophthalmic solution comprising a quaternary ammonium compound, an amine, or a combination thereof, at least one electrolyte, and, optionally, a biologically active agent.
摘要翻译：本发明人已经发现，电解质，例如乙二胺四乙酸（EDTA）的四钠盐，减少眼睛刺激，并增加含有季铵化合物和/或胺的组合物的消毒和消毒功效。结果，含有本发明的季铵化合物和/或胺的浓缩溶液具有低的眼睛刺激性（如果有的话）。此外，使用本发明的浓缩溶液的稀释液包括美国EPA批准用于间接食品接触表面的成分，不同于消毒和消毒含有咪唑啉化合物的组合物。此外，与不含电解质并在硬水中有效的类似组合物相比，使用稀释物对革兰氏阴性细菌和阳性细菌表现出优异的功效。本发明是一种浓缩物，例如消毒和消毒浓缩物，其包含约0.5至约4.0重量％的季铵化合物，胺或其组合和约2.0至约15.0重量％的电解质，基于浓缩物的总重量的100％。浓缩物通常基本上不含咪唑啉化合物。另一个实施方案是包含季铵化合物，胺或其组合，至少一种电解质和任选的生物活性剂的眼用溶液。

8. 发明申请

US20110262330A1 ALKANOLAMINE-BASED CARBON DIOXIDE ABSORPTION SOLUTIONS WITH REDUCED CORROSIVITY 有权
标题翻译：具有降低腐蚀性能的基于烷基胺的二氧化碳吸收解决方案
公开(公告)号：US20110262330A1
公开(公告)日：2011-10-27
申请号：US13125641
申请日：2009-10-26
申请人： Larry Kent Hall , Joseph Kimler , Thomas Bedard
发明人： Larry Kent Hall , Joseph Kimler , Thomas Bedard
IPC分类号： B01D53/62 , C09K3/00
CPC分类号： B01D53/1493 , B01D53/1475 , B01D53/62 , B01D53/77 , B01D53/78 , B01D2251/206 , B01D2257/504 , C23F11/141 , Y02C10/04 , Y02C10/06
摘要： An aqueous carbon dioxide-absorbent solution comprising at least one alkanolamine and at least one quaternary ammonium salt is disclosed. A method of recovering carbon dioxide from a carbon dioxide-containing gaseous mixture and a method of reducing metal corrosion in an alkanolamine-based exhaust gas treating process are also disclosed.
摘要翻译：公开了含有至少一种链烷醇胺和至少一种季铵盐的含水二氧化碳吸收剂溶液。还公开了一种从含二氧化碳气体混合物中回收二氧化碳的方法和在基于链烷醇胺的废气处理方法中还原金属腐蚀的方法。

9. 发明授权

US09168487B2 Alkanolamine-based carbon dioxide absorption solutions with reduced corrosivity 有权
标题翻译：基于烷醇胺的二氧化碳吸收溶液具有降低的腐蚀性
公开(公告)号：US09168487B2
公开(公告)日：2015-10-27
申请号：US13125641
申请日：2009-10-26
申请人： Larry Kent Hall , Joseph Kimler , Thomas Bedard
发明人： Larry Kent Hall , Joseph Kimler , Thomas Bedard
IPC分类号： B01D53/62 , B01D53/78 , B01D53/14 , C23F11/14 , B01D53/77
CPC分类号： B01D53/1493 , B01D53/1475 , B01D53/62 , B01D53/77 , B01D53/78 , B01D2251/206 , B01D2257/504 , C23F11/141 , Y02C10/04 , Y02C10/06
摘要： An aqueous carbon dioxide-absorbent solution comprising at least one alkanolamine and at least one quaternary ammonium salt is disclosed. A method of recovering carbon dioxide from a carbon dioxide-containing gaseous mixture and a method of reducing metal corrosion in an alkanolamine-based exhaust gas treating process are also disclosed.
摘要翻译：公开了含有至少一种链烷醇胺和至少一种季铵盐的含水二氧化碳吸收剂溶液。还公开了一种从含二氧化碳气体混合物中回收二氧化碳的方法和在基于链烷醇胺的废气处理方法中还原金属腐蚀的方法。

10. 发明申请

US20120015986A1 SALTS OF DEHYDROACETIC ACID AS A PYRITHIONE STABILIZER IN PLASTICS 有权
标题翻译：脱水酸作为塑料中的稳定剂的盐
公开(公告)号：US20120015986A1
公开(公告)日：2012-01-19
申请号：US13258874
申请日：2010-03-26
申请人： Larry Kent Hall , Joseph Kimler , Lei Rao
发明人： Larry Kent Hall , Joseph Kimler , Lei Rao
IPC分类号： A61K31/44 , A61P31/10 , C08K5/3432 , A61P31/04
CPC分类号： A01N43/40 , A01N25/22 , A01N2300/00
摘要： The invention provides a method for preventing discoloration of pyrithione-containing materials, in particular plastic materials or other material such as paints, coatings, adhesives or textiles which are exposed to an outdoor environment. The method is likewise suited for preventing discoloration of other pyrithione-containing materials such as personal care compositions like shampoos. A discoloration inhibitor that includes dehydroacetic acid or a salt thereof is added to the pyrithione-containing material. The discoloration is prevented without the addition of a cyclic organic phosphoric acid ester or an organic phosphite. Use of the discoloration inhibitor does not interfere with the antimicrobial effect of the pyrithione.
摘要翻译：本发明提供了防止含吡啶硫酮的材料，特别是塑料材料或暴露于户外环境的其它材料如油漆，涂料，粘合剂或纺织品的变色的方法。该方法同样适用于防止其它含吡啶硫酮的材料如洗发剂等个人护理组合物变色。将含有脱氢乙酸或其盐的变色抑制剂加入含吡啶硫酮的材料中。防止变色，而不加入环状有机磷酸酯或有机亚磷酸酯。使用变色抑制剂不会影响吡啶硫酮的抗微生物作用。

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