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1. 发明申请

US20120141003A1 BACKGROUND FIELD REMOVAL METHOD FOR MRI USING PROJECTION ONTO DIPOLE FIELDS 有权
标题翻译：背景技术用于使用投影到多视场的MRI的现场去除方法
公开(公告)号：US20120141003A1
公开(公告)日：2012-06-07
申请号：US13304141
申请日：2011-11-23
申请人： Yi Wang , Ludovic de Rochefort , Tian Liu , Ildar Khalidov
发明人： Yi Wang , Ludovic de Rochefort , Tian Liu , Ildar Khalidov
IPC分类号： G06K9/34
CPC分类号： G01R33/24 , G01R33/5608 , G06T2207/10088
摘要： For optimal image quality in susceptibility-weighted imaging and accurate quantification of susceptibility, it is necessary to isolate the local field generated by local magnetic sources (such as iron) from the background field that arises from imperfect shimming and variations in magnetic susceptibility of surrounding tissues (including air). We present a nonparametric background field removal method based on projection onto dipole fields in which the background field inside an ROI is decomposed into a field originating from dipoles outside the ROI using the projection theorem in Hilbert space.
摘要翻译：为了在敏感度加权成像和敏感性的准确定量中获得最佳图像质量，需要从由不均匀匀场引起的背景场和周围组织的磁化率变化中分离由局部磁源（如铁）产生的局部场（含空气）。我们提出了一种基于投影到偶极子场的非参数背景场去除方法，其中利用希尔伯特空间中的投影定理将ROI内部的背景场分解成源自ROI外的偶极子的场。

2. 发明申请

US20110044524A1 TOOL FOR ACCURATE QUANTIFICATION IN MOLECULAR MRI 有权
标题翻译：用于精确定量分析MRI的工具
公开(公告)号：US20110044524A1
公开(公告)日：2011-02-24
申请号：US12990148
申请日：2009-04-28
申请人： Yi Wang , Ludovic de Rochefort , Bryan Kressler , Tian Liu , Pascal Spincemaille
发明人： Yi Wang , Ludovic de Rochefort , Bryan Kressler , Tian Liu , Pascal Spincemaille
IPC分类号： G06K9/00
CPC分类号： G01R33/54 , G01R33/5601 , G01R33/5608 , G01R33/563
摘要： A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object. Additionally, the image is used to detect a number of diagnostic features including microbleeds, contract agents and the like.
摘要翻译：提供了用于磁源磁共振成像的方法和装置。该方法包括从对象收集能量信号，提供对象的特征的附加信息，以及从能量信号和附加信息生成对象的图像，使得图像包括特征的定量估计的表示，例如磁化率的定量估计。附加信息可以包括对象的预定特征，从对象产生的幅度图像，或从物体和成像系统之间的不同相对取向收集的磁信号。通过基于收集的信号和附加信息的反转操作来生成图像。反转操作最小化通过组合从所收集的信号提取的数据和对象的附加信息而获得的成本函数。此外，该图像用于检测多个诊断特征，包括微出血，合同代理等。

3. 发明授权

US08781197B2 Tool for accurate quantification in molecular MRI 有权
标题翻译：分子MRI准确定量的工具
公开(公告)号：US08781197B2
公开(公告)日：2014-07-15
申请号：US12990148
申请日：2009-04-28
申请人： Yi Wang , Ludovic de Rochefort , Bryan Kressler , Tian Liu , Pascal Spincemaille
发明人： Yi Wang , Ludovic de Rochefort , Bryan Kressler , Tian Liu , Pascal Spincemaille
IPC分类号： G06K9/00
CPC分类号： G01R33/54 , G01R33/5601 , G01R33/5608 , G01R33/563
摘要： A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object. Additionally, the image is used to detect a number of diagnostic features including microbleeds, contract agents and the like.
摘要翻译：提供了用于磁源磁共振成像的方法和装置。该方法包括从对象收集能量信号，提供对象的特征的附加信息，以及从能量信号和附加信息生成对象的图像，使得图像包括特征的定量估计的表示，例如磁化率的定量估计。附加信息可以包括对象的预定特征，从对象产生的幅度图像，或从物体和成像系统之间的不同相对取向收集的磁信号。通过基于收集的信号和附加信息的反转操作来生成图像。反转操作最小化通过组合从所收集的信号提取的数据和对象的附加信息而获得的成本函数。此外，该图像用于检测多个诊断特征，包括微出血，合同代理等。

4. 发明授权

US09448289B2 Background field removal method for MRI using projection onto dipole fields 有权
标题翻译：使用投影到偶极场上的MRI的背景场去除方法
公开(公告)号：US09448289B2
公开(公告)日：2016-09-20
申请号：US13304141
申请日：2011-11-23
申请人： Yi Wang , Ludovic de Rochefort , Tian Liu , Ildar Khalidov
发明人： Yi Wang , Ludovic de Rochefort , Tian Liu , Ildar Khalidov
IPC分类号： G06K9/00 , G01R33/24 , G01R33/56
CPC分类号： G01R33/24 , G01R33/5608 , G06T2207/10088
摘要： For optimal image quality in susceptibility-weighted imaging and accurate quantification of susceptibility, it is necessary to isolate the local field generated by local magnetic sources (such as iron) from the background field that arises from imperfect shimming and variations in magnetic susceptibility of surrounding tissues (including air). We present a nonparametric background field removal method based on projection onto dipole fields in which the background field inside an ROI is decomposed into a field originating from dipoles outside the ROI using the projection theorem in Hilbert space.
摘要翻译：为了在敏感度加权成像和敏感性的准确定量中获得最佳图像质量，需要从由不均匀匀场引起的背景场和周围组织的磁化率变化中分离由局部磁源（如铁）产生的局部场（含空气）。我们提出了一种基于投影到偶极子场的非参数背景场去除方法，其中利用希尔伯特空间中的投影定理将ROI内部的背景场分解成源自ROI外的偶极子的场。

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