专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09198639B2 Detection of immobilized contrast agent in medical imaging applications based on flow dynamics analysis 有权
标题翻译：基于流动动力学分析的医学成像应用中固定化造影剂的检测
公开(公告)号：US09198639B2
公开(公告)日：2015-12-01
申请号：US12084933
申请日：2006-11-09
申请人： Peter Frinking , Marcel Arditi , Nicolas Rognin , Feng Yan
发明人： Peter Frinking , Marcel Arditi , Nicolas Rognin , Feng Yan
IPC分类号： G06K9/00 , A61B6/00 , A61B5/05 , A61B8/08 , G01S7/52
CPC分类号： A61B8/481 , A61B8/08 , G01S7/52026 , G01S7/52038 , G01S7/52041 , G01S7/52071 , G01S7/52074
摘要： A system for facilitating the detection of an immobilized contrast agent in medical imaging applications is proposed. The system includes means for providing a sequence of a total number of input images obtained at corresponding acquisition instants by imaging a body-part of a patient subjected to an administration of a contrast agent capable of circulating within the patient and of being substantially immobilized on a biological target, each input image including a plurality of input values each one indicative of a response to an interrogation signal of a corresponding portion of the body-part possibly including said contrast agent, and means for reducing a contribution of the circulating contrast agent within the body-part in at least one selected input image; the means for reducing includes means for creating a filtered image corresponding to each selected input image by replacing a set of input values of the selected input image with a set of corresponding filtered values, each filtered value being representative of the lowest response of the corresponding portion of the body-part in a set of multiple input images including the selected input image, the set of multiple input images consisting of a number of input images lower than the total number.
摘要翻译：提出了一种便于在医学成像应用中检测固定的造影剂的系统。该系统包括用于提供在对应的获取时刻获得的输入图像的总数的序列的装置，其通过对经受施用能够在患者内循环的造影剂并且基本上固定在患者身上的患者的体部成像每个输入图像包括多个输入值，每个输入值指示对可能包括所述造影剂的身体部分的对应部分的询问信号的响应;以及用于减少循环造影剂在所述生物靶内的贡献的装置至少一个所选输入图像中的身体部分; 用于减少的装置包括用于通过用一组相应的滤波值替换所选择的输入图像的一组输入值来创建与每个所选择的输入图像相对应的滤波图像的装置，每个滤波值代表相应部分的最低响应包括所选择的输入图像的一组多个输入图像中的身体部分的多个输入图像组合，所述多个输入图像由少于总数的多个输入图像组成。

2. 发明授权

US09072492B2 Quantification analysis of immobilized contrast agent in medical imaging applications 有权
标题翻译：医学成像应用中固定化造影剂的定量分析
公开(公告)号：US09072492B2
公开(公告)日：2015-07-07
申请号：US12811089
申请日：2008-12-23
申请人： Marcel Arditi , Tristan Messager , Michel Schneider , Peter Frinking
发明人： Marcel Arditi , Tristan Messager , Michel Schneider , Peter Frinking
IPC分类号： A61B8/14 , A61B8/08 , G06F19/12
CPC分类号： A61B8/481 , A61B8/14 , A61B8/5223 , G06F19/12
摘要： An embodiment analyzes a body part of a patient, which patient is perfused with a contrast agent that is capable of circulating within the patient and of being substantially immobilized on a biological target. An embodiment of a corresponding system provides an echo signal that is indicative of a response over time to an interrogation signal of the body part, fits the echo signal with a time model function that models an evolution over time of the contrast agent in the body part, the time model function including a combination of a circulation function that models the circulation of the contrast agent and a decay function that models a decay of the echo signal from the immobilized contrast agent, and estimates at least one kinetics indicator of the contrast agent from the time model function.
摘要翻译：一个实施方案分析患者的身体部分，该患者被灌注了能够在患者体内循环并且基本上固定在生物靶上的造影剂。对应系统的一个实施例提供一个回波信号，其指示随着时间的推移对身体部位的询问信号的响应，将回波信号与时间模型函数拟合，该时间模型函数对身体部位中造影剂的时间演化进行建模时间模型功能包括对造影剂的循环进行建模的循环功能和对来自固定的造影剂的回波信号的衰减进行建模的衰减函数的组合，并估计造影剂的至少一个动力学指标时间模型功能。

3. 发明授权

US08512249B2 Detection of the detachment of immobilized contrast agent in medical imaging applications 有权
标题翻译：检测医疗成像应用中固定化造影剂的脱离
公开(公告)号：US08512249B2
公开(公告)日：2013-08-20
申请号：US12520839
申请日：2007-12-21
申请人： Peter Frinking , Tristan Messager , Marcel Arditi , Nicolas Rognin
发明人： Peter Frinking , Tristan Messager , Marcel Arditi , Nicolas Rognin
IPC分类号： A61B5/05 , A61B6/00 , G06K9/00
CPC分类号： G01S7/52041 , A61B8/481 , G01S7/52026 , G01S7/52038 , G01S7/52071 , G01S7/52074
摘要： An input image includes a plurality of input values (i.e., pixel or voxel values), each input value indicative of a response to an interrogation signal of a corresponding location of a body-part, which possibly includes a contrast agent. At least one filtered image is generated from a plurality of selected input images and includes a filtered value for each of a plurality of selected ones of the locations. Each filtered value is indicative of the contrast agent leaving the selected location and is obtained by reducing a contribution of the contrast agent that is substantially stationary at the selected location along the selected input images for a period of time equal to or shorter than a first threshold and by reducing a contribution of the contrast agent that is substantially stationary for a period of time equal to or longer than a second higher threshold.
摘要翻译：输入图像包括多个输入值（即，像素或体元值），每个输入值指示对身体部位的相应位置的询问信号的响应，其可能包括造影剂。从多个选择的输入图像生成至少一个滤波图像，并且包括针对多个选定位置中的每一个的滤波值。每个滤波值表示离开所选择的位置的造影剂，并且是通过在所选择的输入图像的等于或小于第一阈值的时间段内减少基本上静止在选定位置的造影剂的贡献而获得的并且通过减少在等于或长于第二较高阈值的时间段内基本静止的造影剂的贡献。

4. 发明授权

US08036437B2 Perfusion assessment method and system based on animated perfusion imaging 有权
标题翻译：基于动画灌注成像的灌注评估方法和系统
公开(公告)号：US08036437B2
公开(公告)日：2011-10-11
申请号：US11918589
申请日：2006-04-13
申请人： Marcel Arditi , Nicolas Rognin , Peter Frinking
发明人： Marcel Arditi , Nicolas Rognin , Peter Frinking
IPC分类号： G06K9/00
CPC分类号： G06T7/20 , A61B8/06 , A61B8/13 , A61B8/463 , A61B8/481 , A61B8/5238 , G01S15/8977 , G06T2207/30004
摘要： An embodiment of a medical imaging system is proposed. The system includes means for providing a sequence of recorded input images each one offering a digital representation at a corresponding instant of a body part being perfused with a contrast agent, each input image including a plurality of visualizing values each one representing a corresponding portion of the body part, and means for associating each sequence of corresponding sets in the input images of at least one visualizing value with a model function of time; the system further includes means for generating a sequence of computed images at further instants, each computed image including a plurality of further visualizing values each one being determined by an instantaneous function-value which is calculated from the associated model function at the corresponding further instant, and means for displaying the sequence of computed images.
摘要翻译：提出了一种医学成像系统的实施例。该系统包括用于提供一系列记录的输入图像的装置，每个记录的输入图像在与造影剂灌注的身体部位的对应时刻提供数字表示，每个输入图像包括多个可视化值，每个可视化值表示对应部分身体部分，以及用于将至少一个可视化值的输入图像中的对应集合的每个序列与时间的模型函数相关联的装置; 该系统还包括用于在其他时刻产生计算图像序列的装置，每个计算图像包括多个另外的可视化值，每个另外的可视化值由在相应的另外时刻从相关联的模型函数计算的瞬时功能值确定，以及用于显示计算图像序列的装置。

5. 发明申请

US20110213244A1 Real-Time Perfusion Imaging and Quantification 审中-公开
标题翻译：实时灌注成像和定量
公开(公告)号：US20110213244A1
公开(公告)日：2011-09-01
申请号：US13127389
申请日：2009-11-23
申请人： Peter Frinking , Laurent Mercier , Nicolas Rognin , Marcel Arditi
发明人： Peter Frinking , Laurent Mercier , Nicolas Rognin , Marcel Arditi
IPC分类号： A61B8/00
CPC分类号： A61B5/055 , A61B6/504 , A61B6/507 , A61B8/06 , A61B8/481 , G01R33/563 , G01R33/56366
摘要： A solution for diagnostic applications is proposed. Particularly, a corresponding diagnostic system includes means (903-906) for providing (A1-A3) a plurality of input signals representative of a body-part being perfused with a contrast agent over time, each input signal being indicative of a response to an interrogating stimulus of a corresponding location of the body-part possibly including the contrast agent, means (909-930) for generating (A4.1-A4.3) a plurality of filtered signals from selected input signals of selected locations, each filtered signal at each instant over time being generated from a corresponding selected input signal according to a portion of the selected input signal including said instant, and means (933-939) for monitoring (A4.4-A4.6) each filtered signal to detect a peak in the response to the interrogation stimulus of the corresponding selected location, the peak being detected in response to the fulfillment of a stability condition by a corresponding portion of the filtered signal.
摘要翻译：提出了诊断应用的解决方案。特别地，相应的诊断系统包括用于提供（A1-A3）多个输入信号的装置（903-906），所述输入信号表示随时间灌注造影剂的身体部位，每个输入信号指示对用于询问可能包括造影剂的身体部位的对应位置的询问刺激，用于从所选位置的选定输入信号产生（A4.1-A4.3）多个经滤波的信号的装置（909-930），每个滤波信号随着时间的推移，根据包括所述时刻的所选择的输入信号的一部分，从相应的所选择的输入信号产生每个时刻，以及用于监视（A4.4-A4.6）每个滤波信号的装置（933-939），以检测响应于对应选择位置的询问激励的峰值，响应于由滤波信号的相应部分实现稳定性条件而检测到峰值。

6. 发明申请

US20080294027A1 System for extracting morphological information through a perfusion assessment process 有权
标题翻译：通过灌注评估过程提取形态信息的系统
公开(公告)号：US20080294027A1
公开(公告)日：2008-11-27
申请号：US11823098
申请日：2007-06-25
申请人： Peter Frinking , Marcel Arditi , Nicolas Rognin
发明人： Peter Frinking , Marcel Arditi , Nicolas Rognin
IPC分类号： A61B5/145
CPC分类号： A61B8/481 , A61B8/06 , A61B8/13
摘要： A perfusion assessment system is proposed. The system includes means for providing an echo-power signal indicative of a reperfusion of a contrast agent in a body-part of a living subject following destruction of a significant portion of the contrast agent in the body-part, means for associating the echo-power signal to a perfusion function with an S-shape based on a plurality of elementary perfusion functions with said S-shape each one for a corresponding value of at least one perfusion parameter, the elementary perfusion functions being weighted according to a probability density distribution of the at least one perfusion parameter, wherein the S-shape includes an initial portion with substantially zero first derivatives, a final portion with substantially zero first derivatives, and a central portion between the initial portion and the final portion changing monotonically from a value of the initial portion to a value of the final portion, means for determining at least one shape indicator of the probability density distribution, and means for comparing the at least one shape indicator with at least one predetermined further shape indicator to identify morphological characteristics of the body-part according to a result of the comparison.
摘要翻译：提出了灌注评估系统。该系统包括用于在毁坏身体部位中的大部分造影剂之后提供指示生物体的身体部分中的造影剂再灌注的回波功率信号的装置，根据具有所述S形的多个基本灌注函数的具有S形的灌注功能的功能信号，每个具有至少一个灌注参数的对应值，所述基本灌注函数根据概率密度分布进行加权所述至少一个灌注参数，其中所述S形包括具有基本为零的一阶导数的初始部分，具有基本为零的一阶导数的最终部分，以及初始部分与最终部分之间的中心部分从初始部分到最终部分的值，用于确定概率密度分布的至少一个形状指示符的装置离子，以及用于将所述至少一个形状指示器与至少一个预定的另外的形状指示器进行比较的装置，以根据比较的结果来识别身体部位的形态特征。

7. 发明申请

US20120237098A1 PARAMETRIC IMAGES BASED ON DYNAMIC BEHAVIOR OVER TIME 有权
标题翻译：基于动态行为的参考图像
公开(公告)号：US20120237098A1
公开(公告)日：2012-09-20
申请号：US13393633
申请日：2010-09-01
申请人： Nicolas Rognin , Marcel Arditi , Laurent Mercier , Peter Frinking
发明人： Nicolas Rognin , Marcel Arditi , Laurent Mercier , Peter Frinking
IPC分类号： G06K9/00
CPC分类号： G06T7/0016 , G06T2207/10132 , G06T2207/30104
摘要： An embodiment for analyzing a body-part of a patient is proposed. A corresponding data-processing method includes the steps of providing a sequence of input images representing the body-part over an analysis period, each input image including a set of input values each one being indicative of a response to an interrogation signal of a corresponding location of the body-part at a corresponding acquisition instant included in the analysis period, associating an analysis function of time with each one of a set of selected locations, the analysis function modeling a trend of the input values of the selected location in the sequence of input images, and providing a reference function of time for the analysis functions; in an embodiment, the data-processing method further includes comparing the analysis function of each selected location with the reference function to determine a polarity trend representing a trend over the analysis period of a polarity of a divergence between the analysis function of the selected location and the reference function, and creating a parametric image including a parametric value for each selected location, the parametric value being indicative of the polarity trend of the selected location.
摘要翻译：提出了一种用于分析患者身体部位的实施例。相应的数据处理方法包括以下步骤：在分析周期内提供表示身体部分的输入图像序列，每个输入图像包括一组输入值，每个输入值指示对相应位置的询问信号的响应在分析周期中包括的相应采集时刻的身体部分相关联，将时间分析功能与一组选定位置中的每一个相关联，分析功能模拟所选位置的输入值的趋势，输入图像，并提供分析功能的时间参考功能; 在一个实施例中，数据处理方法还包括将每个所选择的位置的分析功能与参考功能进行比较，以确定代表所选位置的分析功能的极性的分析周期的趋势的极性趋势和参考功能，以及创建包括每个选定位置的参数值的参数图像，参数值表示所选位置的极性趋势。

8. 发明申请

US20120082359A1 AUTO-SCALING OF PARAMETRIC IMAGES 有权
标题翻译：参数图像的自动缩放
公开(公告)号：US20120082359A1
公开(公告)日：2012-04-05
申请号：US13377143
申请日：2010-06-08
申请人： Marcel Arditi , Laurent Mercier , Nicolas Rognin , Peter Frinking , Eric Allemann
发明人： Marcel Arditi , Laurent Mercier , Nicolas Rognin , Peter Frinking , Eric Allemann
IPC分类号： G06K9/00
CPC分类号： A61B8/5215 , A61B5/72 , A61B6/5211 , A61B8/06 , A61B8/481 , G06T5/009 , G06T5/40 , G06T2207/10132
摘要： An embodiment is proposed for analyzing a body-part. A corresponding embodiment of a data-processing method includes the steps of providing a parametric map including a plurality of parameter values each one characterizing a corresponding location of the body-part, and determining at least one statistical indicator of at least one distribution of a plurality of analysis parameter values corresponding to selected analysis locations, each statistical indicator being indicative of a condition of an analysis region of the body-part defined by the analysis locations. In an embodiment, the step of determining at least one statistical indicator includes, for each distribution of the analysis parameter values, determining a saturation value partitioning an ordered sequence of processing parameter values, corresponding to selected processing locations at least including the analysis locations, into a first subset and a second subset consisting of a number of the processing parameter values being determined according to a predefined auto-scaling percentage, generating an auto-scaled map including, for each processing location, an auto-scaled value being equal to the corresponding processing parameter value if included in the second subset, or the saturation value if the corresponding processing parameter value is included in the first subset, and determining the at least one statistical indicator from the auto-scaled values corresponding to the analysis locations.
摘要翻译：提出了用于分析身体部位的实施例。数据处理方法的相应实施例包括以下步骤：提供包括表征身体部位的对应位置的多个参数值的参数图，以及确定至少一个多个分布的分布的统计指标对应于所选分析位置的分析参数值，每个统计指标指示由分析位置定义的身体部分的分析区域的状况。在一个实施例中，确定至少一个统计指示符的步骤包括对于分析参数值的每个分布，确定将对应于至少包括分析位置的所选处理位置的处理参数值的有序序列划分为饱和值，由根据预定义的自动缩放百分比确定的多个处理参数值组成的第一子集和第二子集，生成自动缩放图，包括对于每个处理位置，自动缩放值等于相应的如果包括在第二子集中则处理参数值，或者如果相应的处理参数值包括在第一子集中则为饱和值，以及根据与分析位置对应的自动缩放值确定至少一个统计指标。

9. 发明授权

US07912259B2 Image registration method and apparatus for medical imaging based on multiple masks 有权
标题翻译：基于多个掩模的医学成像的图像配准方法和装置
公开(公告)号：US07912259B2
公开(公告)日：2011-03-22
申请号：US11659887
申请日：2005-08-05
申请人： Marcel Arditi , Nicolas Rognin , Tristan Messager , Jean-Philippe Thiran , Ruth Campos
发明人： Marcel Arditi , Nicolas Rognin , Tristan Messager , Jean-Philippe Thiran , Ruth Campos
IPC分类号： G06K9/00
CPC分类号： G06T7/35 , G06T2207/30048
摘要： An image registration method for use in medical imaging includes the steps of: providing a sequence of images each one including a digital representation of a body-part under analysis, selecting a reference image within the sequence, the remaining images of the sequence defining moving images, and re-aligning at least one portion of a moving image with respect to the reference image. The step of re-aligning may include: defining a delimitation mask identifying a region on the reference image with which the at least one portion of the moving image has to be re-aligned, and a feature mask identifying a further region on the reference image within which the re-alignment is calculated, determining an optimized transformation for compensating a displacement of the moving image with respect to the reference image by optimizing a similarity measure, and transforming the at least one portion of the moving image according to the optimized transformation.
摘要翻译：用于医学成像的图像配准方法包括以下步骤：提供每个图像序列，每个图像序列包括正在分析的身体部位的数字表示，选择序列内的参考图像，定义运动图像的序列的剩余图像并且相对于参考图像重新对准运动图像的至少一部分。重新对准的步骤可以包括：定义标识在参考图像上必须重新对齐运动图像的至少一部分的参考图像上的区域的定界掩模，以及标识参考图像上的另外区域的特征掩模在其中计算重新对准，通过优化相似性度量来确定用于补偿运动图像相对于参考图像的位移的优化变换，以及根据优化的变换来变换运动图像的至少一部分。

10. 发明申请

US20090028406A1 Perfusion Assessment Based on Animated Perfusion Imaging 有权
标题翻译：基于动画灌注成像的灌注评估
公开(公告)号：US20090028406A1
公开(公告)日：2009-01-29
申请号：US11918589
申请日：2006-04-13
申请人： Marcel Arditi , Nicolas Rognin , Peter Frinking
发明人： Marcel Arditi , Nicolas Rognin , Peter Frinking
IPC分类号： A61B8/00
CPC分类号： G06T7/20 , A61B8/06 , A61B8/13 , A61B8/463 , A61B8/481 , A61B8/5238 , G01S15/8977 , G06T2207/30004
摘要： An embodiment of a medical imaging system is proposed. The system includes means for providing a sequence of recorded input images each one offering a digital representation at a corresponding instant of a body part being perfused with a contrast agent, each input image including a plurality of visualizing values each one representing a corresponding portion of the body part, and means for associating each sequence of corresponding sets in the input images of at least one visualizing value with a model function of time; the system further includes means for generating a sequence of computed images at further instants, each computed image including a plurality of further visualizing values each one being determined by an instantaneous function-value which is calculated from the associated model function at the corresponding further instant, and means for displaying the sequence of computed images.
摘要翻译：提出了一种医学成像系统的实施例。该系统包括用于提供一系列记录的输入图像的装置，每个记录的输入图像在与造影剂灌注的身体部位的对应时刻提供数字表示，每个输入图像包括多个可视化值，每个可视化值表示对应部分身体部分，以及用于将至少一个可视化值的输入图像中的对应集合的每个序列与时间的模型函数相关联的装置; 该系统还包括用于在其他时刻产生计算图像序列的装置，每个计算图像包括多个另外的可视化值，每个另外的可视化值由在相应的另外时刻从相关联的模型函数计算的瞬时功能值确定，以及用于显示计算图像序列的装置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式