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1. 发明申请

US20120141448A1 Method for increasing muscle mass and strength 审中-公开
标题翻译：增加肌肉质量和强度的方法
公开(公告)号：US20120141448A1
公开(公告)日：2012-06-07
申请号：US13373649
申请日：2011-11-23
申请人： Lorenzo De Ferra , Marvin Heuer , Scott Hagerman , Martin Purpura , Ralf Jäger
发明人： Lorenzo De Ferra , Marvin Heuer , Scott Hagerman , Martin Purpura , Ralf Jäger
IPC分类号： A61K31/685 , A61K38/16 , A61K38/28 , A61P21/06 , A61K38/27 , A61K31/122 , A61K33/24 , A61K33/06 , A61K31/661 , A61K38/30
CPC分类号： A61K31/122 , A61K31/198 , A61K31/661 , A61K31/685 , A61K33/06 , A61K33/24 , A61K35/20 , A61K38/014 , A61K38/1709 , A61K38/27 , A61K38/28 , A61K38/30 , A61K45/06 , A61K2300/00
摘要： Phosphatidic acid is administered orally to increase muscle mass and strength in exercising mammals. Phosphatidic acid is administered orally to aging, bedridden or cachectic patients to improve nitrogen balance. The preferred form of phosphatidic acid for administration is phosphatidic acid-enriched lecithin. Creatine is co-administered orally to increase the muscle-building and strength effect. Other suggested additives include nutritional and herbal supplements, micronutrients and hormones.
摘要翻译：口服施用磷脂酸以增加运动哺乳动物的肌肉质量和强度。磷酸酯口服给老化，卧床或恶病质患者，以改善氮平衡。用于给药的磷脂酸的优选形式是富含磷脂酸的卵磷脂。肌酸共同口服以增加肌肉的建立和强度的作用。其他建议的添加剂包括营养和草药补充剂，微量营养素和激素。

2. 发明申请

US20060280843A1 Filler for a beverage container 审中-公开
标题翻译：饮料容器填料
公开(公告)号：US20060280843A1
公开(公告)日：2006-12-14
申请号：US11431904
申请日：2006-05-10
申请人： Ralf Jager , Martin Purpura , Reinhard Kroner
发明人： Ralf Jager , Martin Purpura , Reinhard Kroner
IPC分类号： B65D85/00
CPC分类号： A23L2/52 , A23L2/40
摘要： The present invention comprises a filler material for a container having at least one compartment, which container is situated in a pressurized beverage container and, immediately after the beverage container is opened, is suitable for mixing the filling into the drinks liquid surrounding the container. The filling itself is in granule form of defined particle diameter and is composed, in particular, of the main component a) in the form of a food supplement and an effervescent component b). The component a) which should be present in the filling in amounts of between 35 and 98% by weight can also be pharmaceutical active ingredients, vitamins, creatine derivatives, phospholipids, probiotics, minerals, unsaturated fatty acids and any desired mixtures thereof. The fillings can be introduced into drinks liquids of varying pH, since, because of its solubility and due to the targeted selection of suitable effervescent and disintegrant components, can be rapidly and completely dissolved or suspended in the drinks liquid.
摘要翻译：本发明包括用于容器的填充材料，其具有至少一个隔室，该容器位于加压饮料容器中，并且在饮料容器打开之后立即适于将填充物混合到容器周围的饮料液体中。填充物本身是确定粒径的颗粒形式，特别是以食品补充剂和泡腾组分b）的形式组成的主要组分a）。在填充物中应该含量为35至98重量％的组分a）还可以是药物活性成分，维生素，肌酸衍生物，磷脂，益生菌，矿物质，不饱和脂肪酸及其任何所需的混合物。由于其溶解性和适当的泡腾剂和崩解剂组分的目标选择，因此可将填充物引入不同pH的饮料液体中，因此可快速且完全地溶解或悬浮于饮料液体中。

3. 发明申请

US20080020995A1 Use of Cyclodextrin Complexes Containing Lipoic Acid 审中-公开
公开(公告)号：US20080020995A1
公开(公告)日：2008-01-24
申请号：US11720350
申请日：2005-08-08
申请人： Martin Purpura , Wolfgang Schutt
发明人： Martin Purpura , Wolfgang Schutt
IPC分类号： A61K31/724 , A61P17/00 , A61P25/00 , A61P3/00
CPC分类号： A61K31/385 , A23L33/10 , A23V2002/00 , A61K8/4986 , A61K8/738 , A61K31/20 , A61K47/6951 , A61K2800/56 , A61K2800/92 , A61Q19/00 , B82Y5/00 , A23V2250/5114 , A23V2250/026 , A23V2250/032 , A23V2250/242 , A23V2250/2482
摘要： The invention relates to the use of cyclodextrin complexes containing lipoic acid, said complexes consisting of at least one representative of the series of unsubstituted α-cyclodextrin, β-cyclodextrin and γ-cyclodextrin, and at least one representative of the series of racemic α-lipoic acid, racemic dihydrolipoic acid and the derivatives thereof, for producing a food supplement, a functional food supplement, a clinical nutrition product and/or a cosmetic preparation in the non-medical field of application. Said complex, which contains at least 20 wt. % of the cyclodextrin component, preferably in food quality, can also contain water and reaction products or secondary reaction products from the complex production, especially α-cyclodextrin being used. The cyclodextrin/(dihydro)liponic acid complexes can be used, preferably combined with other bioactive components, aromas and/or texturing products, and also the standard formulation auxiliary agents, to produce an agent for preventing and/or treating symptoms of an inflammatory nature and especially arthritis, damage to the liver function and especially alcohol intoxication, paraesthesiae and neuropathies, and for producing agents having cytoprotective and/or antiphlogistic and/or antinociceptive (analgesic) properties and/or properties that counteract the formation of radicals. Said complexes can also preferably be used to produce an agent for stimulating glucose metabolism and/or transport in muscles and/or lipocytes, agents for reinforcing the energy metabolism of the body and the brain, agents for increasing the endurance, capacity, attentiveness, concentration of the memory, agents for the prevention and/or treatment of diabetes Typ2, and agents for caring for at least partially keratinised parts of the body, especially the skin, hair, fingernails and toenails. The invention enables products to be obtained, which can be taken by the end consumer under improved compliance conditions in the non-medical field of indication, due to the distinctive stability of the agents.

4. 发明申请

US20070009590A1 Physiologically active composition based on phosphatidylserine 审中-公开
标题翻译：基于磷脂酰丝氨酸的生理活性成分
公开(公告)号：US20070009590A1
公开(公告)日：2007-01-11
申请号：US10570071
申请日：2004-09-03
申请人： Martin Purpura , Ralf Jager , Roland Rabeler , Hans-Ullrich Hoppe
发明人： Martin Purpura , Ralf Jager , Roland Rabeler , Hans-Ullrich Hoppe
IPC分类号： A61K31/685 , A61K9/20
CPC分类号： A61K31/661 , A23L33/12 , A23V2002/00 , A61K31/683 , A61K31/685 , A61K2300/00 , A23V2250/1852 , A23V2250/1842 , A23V2250/0642 , A23V2250/1868
摘要： This physiologically active composition contains, as physiologically active constituents, the components a) phosphatidylserine and/or lysophosphatidylserine (in each case “PS”) and b) at least one (lyso)phospholipid different from component a) and c) a serine source different from component a), for example L-serine and/or O-phospho-L-serine. In this composition, the components a) and also b) and c) must each be present in a molar ratio a:b (where b
摘要翻译：作为生理活性组分，该生理活性组合物含有组分a）磷脂酰丝氨酸和/或溶血磷脂酰丝氨酸（在每种情况下为“PS”），和b）不同于组分a）的至少一种（溶血）磷脂，和c）丝氨酸源不同来自组分a），例如L-丝氨酸和/或O-磷酸-L-丝氨酸。在该组合物中，组分a）和b）和c）必须各自以摩尔比a：b（其中b

5. 发明申请

US20050220857A1 Physiologically compatible, phospholipid-containing, stable and hard matrix 审中-公开
标题翻译：生理相容，含磷脂，稳定和硬质基质
公开(公告)号：US20050220857A1
公开(公告)日：2005-10-06
申请号：US10511884
申请日：2003-04-17
申请人： Martin Purpura , Dirk Cremer , Ralf Jager , Michaela Thalhammer
发明人： Martin Purpura , Dirk Cremer , Ralf Jager , Michaela Thalhammer
IPC分类号： A23L1/30 , A23J7/00 , A23L1/00 , A61K9/16 , A61K9/50 , A61K31/683 , A61K31/685 , A61K31/688 , A61K47/04 , A61K47/14 , A61K47/26 , A61K47/36 , A61K47/38 , A61K47/42 , A61K47/44 , A61P3/06 , A61P3/10 , A61P25/22 , A61P43/00 , A61K9/127
CPC分类号： A23J7/00 , A23P10/30 , A23P10/35 , A23V2002/00 , A61K9/1617 , A23V2200/224 , A23V2250/1846 , A23V2250/1842 , A23V2250/1852
摘要： The invention concerns a physiologically compatible, phospholipid-containing, stable and hard matrix consisting of a supporting material and a bioactive component which has a total diameter of between 0.1 and 5000 μm and contains ≧5% by weight, based on the starting material, of acetone-insoluble components as the bioactive component, which are in particular phosphatidyl serine, phosphatidyl choline and such like, as well as lyso variants and/or derivatives thereof. This matrix which preferably has a supporting material consisting of carbohydrates and/or proteins and preferably additional bioactive substances as ingredients such as amino acids, vitamins, trace elements and similar substances, can have liquid contents and is used in particular in functional foods, special foods and dietary supplements.
摘要翻译：本发明涉及一种生理上相容的含磷脂，稳定和硬质基质，其由支撑材料和生物活性成分组成，其总直径为0.1-5000μm，并且基于起始原料含有≥5重量％作为生物活性成分的丙酮不溶性成分，特别是磷脂酰丝氨酸，磷脂酰胆碱等，以及其溶血变体和/或衍生物。该基质优选具有由碳水化合物和/或蛋白质组成的支持材料，优选作为成分例如氨基酸，维生素，微量元素和类似物质的附加生物活性物质可以具有液体内容物，特别用于功能食品，特殊食品和膳食补充剂。

6. 发明申请

US20050096392A1 Use of creatine pyruvate for increasing stamina during highly intensive intermittent physical exertion 审中-公开
标题翻译：在高度密集的间歇性体力劳动下，使用肌酸丙酮酸可增加体力
公开(公告)号：US20050096392A1
公开(公告)日：2005-05-05
申请号：US10510173
申请日：2003-04-03
申请人： Ralf Jager , Martin Purpura , Dirk Bokenkamp
发明人： Ralf Jager , Martin Purpura , Dirk Bokenkamp
IPC分类号： A23L1/29 , A23L1/305 , A61K31/155 , A61K31/19 , A61K31/195 , A61P3/02 , A61P21/00 , A61K31/205
CPC分类号： A61K31/195 , A23L33/175 , A23L33/30
摘要： The invention relates to the use of creatine pyruvate for increasing stamina during highly intensive intermittent physical exertion. Said use is to be applied in particular during short-term intensive muscular exertion and/or muscular exertion of short-duration and/or that is repeated in short intervals, preferably during sprinting and sporting performances in running disciplines and during exercises using sports equipment provided with rollers, wheels or sliding surfaces, in addition to during raising, pulling and/or lifting movements of the extremities and the neck. The invention relates in particular to variants, in which muscular exertion is maintained for between 0.1 seconds and 5 minutes and/or during which the muscular exertion is carried out with a frequency of between 0.1 and 600 minutes. In the latter variant, the muscular exertion can increase with each interval. The creatine pyruvate is administered in the required application in daily doses of between 500 mg and 30 g and in particular over a period of between 1 day and 12 weeks in powder, lozenge, capsule or coated tablet form, in liquids and also as a food supplement or functional food.
摘要翻译：本发明涉及肌酸丙酮酸盐在高度密集间歇体力劳动中增加体力的用途。所述用途特别是在短时间强化的肌肉劳动和/或短时间的肌肉劳动和/或短时间间隔内重复使用，优选地在运动学科的冲刺和运动表现期间以及使用所提供的运动设备的运动期间除了在四肢和颈部的升高，拉动和/或提升运动期间，还有滚子，轮子或滑动表面。本发明特别涉及变体，其中肌肉运动维持在0.1秒和5分钟之间和/或在此期间以0.1-600分钟的频率进行肌肉劳动。在后一种变型中，肌肉力量可以随着每个间隔而增加。在所需的应用中，肌酸丙酮酸以500mg至30g之间的日剂量施用，特别是在粉末，锭剂，胶囊或包衣片剂形式的液体中，还可作为食物施用1到12周的时间补充或功能食品。

7. 发明申请

US20170079311A1 METHOD FOR INCREASING ABSORPTION OF PLANT DERIVED PROTEINS 审中-公开
公开(公告)号：US20170079311A1
公开(公告)日：2017-03-23
申请号：US14857811
申请日：2015-09-17
申请人： Ralf Jager , Mark Olson , Joseph P. Mannion , Jaroslav Boublik , Martin Purpura
发明人： Ralf Jager , Mark Olson , Joseph P. Mannion , Jaroslav Boublik , Martin Purpura
IPC分类号： A23K1/18
CPC分类号： A23L33/18 , A23L29/06 , A23L33/175 , A23L33/30 , A23V2002/00
摘要： A method for improving the absorption of amino acids from protein sources include adding one or more carbohydrases to a protein source. Plant protein such as that found in rice may be extracted to provide a rice concentrate useful in regimens requiring elevated amounts of protein consumption. To improve the absorption of the amino acids found in rice inside the human gastrointestinal tract, a carbohydrases such as Alpha-galactidase is added to the protein source prior to ingestion. The composition may also include proteases.

8. 发明申请

US20090005322A1 Physiologically- Active Composition Based on Collagen 失效
标题翻译：基于胶原蛋白的生理活性成分
公开(公告)号：US20090005322A1
公开(公告)日：2009-01-01
申请号：US11658437
申请日：2005-07-27
申请人： Martin Purpura , Ralf Jager , Karim Balan , Dietrich Paper
发明人： Martin Purpura , Ralf Jager , Karim Balan , Dietrich Paper
IPC分类号： A61K38/17 , A61P29/00
CPC分类号： A61K36/68 , A23L33/105 , A23L33/18 , A61K31/353 , A61K36/16 , A61K36/185 , A61K36/85 , A61K36/886 , A61K38/014 , A61K45/06 , A61K2300/00
摘要： The present invention concerns a physiologically active composition which contains an enzymatically hydrolysed collagen as the active component I and at least one component of the non-vitamin type having anti-oxidative and/or anti-inflammatory properties as the active component II. Collagen of animal origin that is soluble in cold water comes into particular consideration as component I and a fermentation broth or a plant extract comes into particular consideration as component II. This composition which is designed in particular as a food supplement or functional food can be used to prevent inflammatory and/or degenerative symptoms in particular with a chronic course such as for example arthritis and arthroses or to successfully treat these symptoms. The claimed composition can be used above all by professional, leisure and recreational athletes who suffer in particular from strained joint functions.
摘要翻译：本发明涉及一种生理活性组合物，其含有作为活性组分I的酶水解胶原蛋白和至少一种具有作为活性组分II的抗氧化和/或抗炎特性的非维生素类成分。可溶于冷水的动物来源的胶原蛋白作为组分I特别考虑，发酵液或植物提取物作为组分II被特别考虑。特别设计为食品补充剂或功能性食品的该组合物可用于预防特别是慢性病症例如关节炎和关节炎的炎症和/或退行性症状，或成功治疗这些症状。所声称的组合物可以由专门从事紧张关节功能的专业，休闲和娱乐运动员使用。

9. 发明申请

US20060263486A1 Filler material for a beverage container 审中-公开
标题翻译：用于饮料容器的填充材料
公开(公告)号：US20060263486A1
公开(公告)日：2006-11-23
申请号：US11131921
申请日：2005-05-18
申请人： Ralf Jager , Martin Purpura , Reinhard Kroner
发明人： Ralf Jager , Martin Purpura , Reinhard Kroner
IPC分类号： A23L1/30
CPC分类号： A23L2/395 , A23L2/52
摘要： The subject of the present invention relates to a filler material for a container having at least one chamber which is situated in a beverage container under pressure and immediately after the opening of the beverage container is suitable for the admixture of the filler material into the beverage liquid surrounding it. The filler material itself is in granule form and is composed of the chief component a) in the form of a nutritional supplement and an effervescent component b). The component a), which should be present in the filler material in percentages between 35 and 98 wt.-%, can be non-prescription agents, vitamins, creatine derivatives, phospholipids, probiotics, minerals, unsaturated fatty acids and any mixtures thereof. The fillers can be put into beverage liquids with varying pH, since due to their dissolving ability and due to the targeted selection of appropriate effervescence and bursting components can be dissolved quickly and completely in the beverage liquid.
摘要翻译：本发明的主题涉及一种用于容器的填充材料，其具有至少一个室，该室在压力下位于饮料容器中，并且在饮料容器的开口后立即适于将填料混合到饮料液体中围绕它。填充材料本身为颗粒形式，由营养补充剂和泡腾组分b）形式的主要组分a）组成。组分a），其应以35至98重量％之间的百分比存在于填料中可以是非处方剂，维生素，肌酸衍生物，磷脂，益生菌，矿物质，不饱和脂肪酸及其任何混合物。填充剂可以放入具有不同pH值的饮料液体中，因为它们的溶解能力和由于目标选择合适的泡腾和爆破组分可以快速且完全地溶解在饮料液体中。

10. 发明申请

US20050175763A1 Functional foods containing a phospholipid-containing stable matrix 审中-公开
标题翻译：含有磷脂的稳定基质的功能性食品
公开(公告)号：US20050175763A1
公开(公告)日：2005-08-11
申请号：US10511885
申请日：2003-04-17
申请人： Martin Purpura , Dirk Cremer , Ralf Jager , Michaela Thalhammer
发明人： Martin Purpura , Dirk Cremer , Ralf Jager , Michaela Thalhammer
IPC分类号： A23J7/00 , A23L1/00 , A23L1/30 , A61K9/16 , A61K9/20 , A61K9/48 , A61K9/50 , A61K31/683 , A61K31/685 , A61K47/04 , A61K47/14 , A61K47/24 , A61K47/26 , A61K47/30 , A61K47/36 , A61K47/38 , A61K47/42 , A61K47/44 , A61P3/06 , A61P3/10 , A61P25/00 , A23D7/00
CPC分类号： A61K9/2013 , A23L33/10 , A23P10/30 , A23P10/35 , A23V2002/00 , A61K9/4858 , A23V2200/224 , A23V2250/1852 , A23V2250/1846
摘要： The claimed functional foods and specialized foods each contain a physiologically compatible phospholipid-containing stable matrix consisting of a supporting material and a bioactive component, the phospholipid component being in particular phosphatidyl serine, phosphatidyl choline and similar compounds, lyso variants and/or derivatives thereof. Liquid, solid and semiliquid forms of administration are preferred as the functional foods; food for tube feeding is regarded as preferred among the specialized foods. The matrix used for this should preferably have liquid contents and in particular have a diameter between 0.1 μm and 5.0 mm. It is also preferred when the matrix develops a delayed release after its ingestion with the respective foods which should preferably take place in the gastro-intestinal tract.
摘要翻译：所要求保护的功能食品和专门食品各自含有由支持材料和生物活性成分组成的生理上相容的含磷脂的稳定基质，磷脂成分特别是磷脂酰丝氨酸，磷脂酰胆碱和类似化合物，溶血变体和/或其衍生物。作为功能食品，优选液体，固体和半液体的给药形式; 用于管饲的食物被认为是专门食品中的首选。用于此的基质应优选具有液体含量，特别是具有0.1μm和5.0mm之间的直径。当基质在摄取后应该优选在胃肠道中发生的相应食物时，基质产生延迟释放也是优选的。

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