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1. 发明申请

US20150360053A1 PARTICLE BEAM IRRADIATION SYSTEM AND PARTICLE BEAM THERAPY SYSTEM PROVIDED THEREWITH 审中-公开
标题翻译：颗粒光束辐照系统和粒子束治疗系统
公开(公告)号：US20150360053A1
公开(公告)日：2015-12-17
申请号：US14761850
申请日：2013-01-22
申请人： Yuehu PU , Masahiro IKEDA , Taizo HONDA
发明人： Yuehu PU , Masahiro IKEDA , Taizo HONDA
IPC分类号： A61N5/10
CPC分类号： A61N5/1043 , A61N5/103 , A61N5/1048 , A61N5/1071 , A61N5/1077 , A61N2005/1074 , A61N2005/1087
摘要： A particle beam irradiation system comprising a scanning electromagnet for a particle beam to scan an irradiation objective, a scanning information storage section for storing scanning position information regarding a plurality of scanning positions in a case where a particle beam scans an irradiation objective and scanning order information which is order for scanning a plurality of scanning positions, and a scanning electromagnet control section for controlling a scanning electromagnet based on scanning position information and scanning order information which is stored in the scanning information storage section, wherein the scanning position information which is stored in the scanning information storage section includes a part whose scanning position information is same as the scanning position information of adjacent order.
摘要翻译：一种粒子束照射系统，包括用于粒子束的扫描电磁体扫描照射物镜;扫描信息存储部分，用于在粒子束扫描照射物镜和扫描命令信息的情况下存储关于多个扫描位置的扫描位置信息扫描位置信息存储在扫描信息存储部中，扫描位置信息存储在扫描信息存储部中，扫描位置信息存储在扫描信息存储部中，扫描信息存储部分包括扫描位置信息与相邻次序的扫描位置信息相同的部分。

2. 发明授权

US09101763B2 Particle beam irradiation apparatus having adjustable low-scattering filling chamber and particle beam therapy system 有权
标题翻译：具有可调低散射填充室和粒子束治疗系统的粒子束照射装置
公开(公告)号：US09101763B2
公开(公告)日：2015-08-11
申请号：US14240650
申请日：2011-11-03
申请人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
发明人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
IPC分类号： A61N5/00 , A61N5/10
CPC分类号： A61N5/1081 , A61N5/1077 , A61N2005/1087 , A61N2005/1095
摘要： A particle beam irradiation apparatus according to the present invention is provided with a vacuum duct that forms a vacuum region through which the charged particle beam passes, a vacuum window through which the charged particle beam is launched from the vacuum region, a scanning electromagnet that scans the charged particle beam; a monitoring apparatus including a position monitor that detects the passing position of a charged particle beam and the beam size thereof, a low-scattering gas filling chamber including the monitoring apparatus, and an irradiation management apparatus that controls irradiation of the charged particle beam; the particle beam irradiation apparatus is characterized in that the low-scattering gas filling chamber is changeably disposed in such a manner that the beam-axis-direction positional relationship between the monitoring apparatus and the vacuum window is a desired one and in that the low-scattering gas filling chamber is filled with a low-scattering gas.
摘要翻译：根据本发明的粒子束照射装置设置有真空管道，该真空管道形成带电粒子束通过的真空区域，从真空区域发射带电粒子束的真空窗口，扫描的扫描电磁体带电粒子束; 监视装置，其包括检测带电粒子束的通过位置的位置监视器及其光束尺寸，包括监视装置的低散射气体填充室以及控制带电粒子束的照射的照射管理装置; 所述粒子束照射装置的特征在于，所述低散射气体充填室可变地设置成使得所述监视装置和所述真空窗口之间的射束轴向位置关系是期望的，散射气体填充室填充有低散射气体。

3. 发明授权

US09079026B2 Particle beam scanning irradiation system 有权
标题翻译：粒子束扫描照射系统
公开(公告)号：US09079026B2
公开(公告)日：2015-07-14
申请号：US14386626
申请日：2012-03-21
申请人： Yuehu Pu , Masahiro Ikeda , Taizo Honda
发明人： Yuehu Pu , Masahiro Ikeda , Taizo Honda
IPC分类号： A61N5/10
CPC分类号： A61N5/1071 , A61N5/103 , A61N5/1031 , A61N5/1043 , A61N2005/1087
摘要： A particle beam scanning irradiation method includes the steps of calculating a planned irradiating particle count of a particle beam for each of irradiation spots, on the basis of a relative amount of particle beam irradiation and a prescription particle-beam dose determined from a particle-beam therapy plan; simulating an irradiation process of the particle beam at each irradiation spot, on the basis of the planned irradiating particle count and a beam current waveform of the particle beam, and calculating a particle count of the particle beam irradiating the diseased portion during a scan shift of the particle beam; correcting the planned irradiating particle count for each irradiation spot by using the irradiating particle count during the scan shift; converting the corrected planned-irradiation particle count into a count value used in a dose monitor; and irradiating the irradiation spot with the particle beam, on the basis of the converted count value.
摘要翻译：粒子束扫描照射方法包括以下步骤：基于粒子束照射的相对量和从粒子束确定的处方粒子束剂量来计算每个照射点的粒子束的计划照射粒子数治疗方案; 基于所计划的照射粒子数和粒子束的束电流波形，模拟在各照射点处的粒子束的照射过程，计算在扫描位移期间照射患病部位的粒子束的粒子数粒子束; 通过使用扫描偏移期间的照射粒子数来校正每个照射点的计划照射粒子数; 将校正的计划照射粒子数转换为剂量监视器中使用的计数值; 并且基于转换后的计数值，用粒子束照射照射点。

4. 发明授权

US09067065B2 Particle beam irradiation apparatus and particle beam therapy system utilizing a beam position monitor to provide feedback adjustments based on the beam position 有权
标题翻译：使用光束位置监测器的粒子束照射装置和粒子束治疗系统基于光束位置提供反馈调节
公开(公告)号：US09067065B2
公开(公告)日：2015-06-30
申请号：US13977058
申请日：2011-03-07
申请人： Yukiko Yamada , Hisashi Harada , Takaaki Iwata , Toshihiro Otani , Masahiro Ikeda , Kazushi Hanakawa , Taizo Honda
发明人： Yukiko Yamada , Hisashi Harada , Takaaki Iwata , Toshihiro Otani , Masahiro Ikeda , Kazushi Hanakawa , Taizo Honda
IPC分类号： A61N5/10 , G21K1/093
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1075 , A61N2005/1087 , G21K1/093
摘要： The particle beam irradiation apparatus comprises: a position monitor that detects a passing position of a charged particle beam; and an irradiation control apparatus that calculates a distance from a predetermined reference point to the position monitor, calculates a beam irradiation position on an irradiation subject, and controls irradiation of the beam; wherein the irradiation control apparatus includes a position calculation apparatus that calculates the beam irradiation position, based on a beam position detected by the position monitor, a scanning starting point distance information on a distance from a irradiation plane of the irradiation subject to a scanning starting point, of the beam, in a scanning electromagnet, and a position monitor distance information on a distance, from the irradiation plane to the position monitor, that is calculated based on the calculated distance.
摘要翻译：粒子束照射装置包括：位置监视器，其检测带电粒子束的通过位置; 以及照射控制装置，其计算从预定基准点到所述位置监视器的距离，计算照射对象的光束照射位置，并控制所述光束的照射; 其特征在于，所述照射控制装置包括：位置计算装置，其基于由所述位置监视器检测到的光束位置计算所述光束照射位置;从所述照射对象的照射面到扫描开始点的距离的扫描开始点距离信息，扫描电磁体中的距离信息，以及从照射平面到位置监视器的基于计算出的距离计算的位置监视距离信息。

5. 发明申请

US20150080631A1 PARTICLE BEAM SCANNING IRRADIATION SYSTEM 有权
标题翻译：粒子束扫描辐射系统
公开(公告)号：US20150080631A1
公开(公告)日：2015-03-19
申请号：US14390087
申请日：2012-05-14
申请人： Yuehu Pu , Masahiro Ikeda
发明人： Yuehu Pu , Masahiro Ikeda
IPC分类号： A61N5/10
CPC分类号： A61N5/1043 , A61N5/103 , A61N5/1044 , A61N2005/1087 , F04C2270/0421
摘要： A particle beam scanning irradiation system includes a computer establishing a scanning sequence for irradiation of a tumor portion in a patient; and a particle beam irradiation device irradiating the tumor portion in accordance with the established scanning sequence of the particle beam. The computer selects all conceivable combinations of pairs of irradiation spots among the plurality of irradiation spots arranged in the tumor portion, and determines whether each path for the particle beam to shift between two spots constituting the selected pair passes through the tumor portion; determines a penalty matrix expressing whether each path passes through the tumor portion on the basis of the determination result; evaluates a function for the shift paths on the basis of an optimizing algorithm, and establishes the scanning sequence of the particle beam by an optimized solution of the function.
摘要翻译：粒子束扫描照射系统包括建立用于照射患者肿瘤部分的扫描序列的计算机; 以及根据建立的粒子束扫描顺序照射肿瘤部分的粒子束照射装置。计算机选择布置在肿瘤部分中的多个照射点之间的所有可能的照射点对的组合，并且确定用于粒子束在构成所选择的对的两个点之间移动的每个路径是否通过肿瘤部分; 根据确定结果确定表示每个路径是否通过肿瘤部分的惩罚矩阵; 基于优化算法对移位路径的功能进行评估，并通过优化的功能解决方案建立粒子束的扫描序列。

6. 发明申请

US20140323793A1 PARTICLE BEAM THERAPY DEVICE AND PARTICLE BEAM THERAPY DEVICE OPERATION METHOD 有权
标题翻译：颗粒束治疗装置和颗粒束治疗装置操作方法
公开(公告)号：US20140323793A1
公开(公告)日：2014-10-30
申请号：US14356629
申请日：2012-03-27
申请人： Yukiko Yamada , Hisashi Harada , Taizo Honda , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose
发明人： Yukiko Yamada , Hisashi Harada , Taizo Honda , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1077 , A61N2005/1074 , A61N2005/1087 , H05H13/04 , H05H2277/11
摘要： A control unit is provided with, a retaining section that retains a plurality of operation patterns each being a pattern of operation to be periodically repeated by an accelerator, the operation patterns having respective operation conditions adjusted for different emission times of an particle beam, to cause a deflection electromagnet in the accelerator to have an intended magnetic field intensity even under a presence of a hysteresis; a reading section for a plurality of slices of an irradiation target in a depth direction, which reads an irradiation condition for each of the slices; a selection section that selects the operation pattern suitable for each of the slices, on the basis of the read irradiation condition; and a main control section that controls, for each of the slices, the accelerator on the basis of the selected operation pattern and an irradiation device on the basis of the irradiation condition.
摘要翻译：控制单元设置有保持部，其保持多个操作模式，每个操作模式是由加速器周期性重复的操作模式，所述操作模式具有针对粒子束的不同发射次数调整的各自的操作条件，以使得加速器中的偏转电磁体即使在滞后的情况下也具有预期的磁场强度; 用于读取每个切片的照射条件的用于在深度方向上的照射目标的多个切片的读取部分; 选择部，其基于读取的照射条件选择适合于每个切片的操作模式; 以及主控制部，其基于所述照射条件，基于所选择的操作模式和照射装置对每个切片进行加速器的控制。

7. 发明授权

US08772733B2 Charged particle accelerator and particle beam therapy system 有权
标题翻译：带电粒子加速器和粒子束治疗系统
公开(公告)号：US08772733B2
公开(公告)日：2014-07-08
申请号：US13582645
申请日：2012-01-26
申请人： Masahiro Ikeda , Yuko Kijima , Shunsuke Okada
发明人： Masahiro Ikeda , Yuko Kijima , Shunsuke Okada
IPC分类号： H01J3/14 , A61N5/00
CPC分类号： H05H13/04 , A61N2005/1087 , H05H2007/046 , H05H2277/11
摘要： The objective is to obtain a charged particle accelerator where the amount of pattern data for operating an acceleration cavity and electromagnets based on time clocks is reduced and the pattern data communication time is shortened. An accelerator control apparatus provided in a charged particle accelerator of the present invention is characterized by including a clock generation unit that generates an acceleration cavity clock and an electromagnet clock that is synchronized with the acceleration cavity clock and has a frequency lower than that of the acceleration cavity clock; a high-frequency control unit that controls an acceleration cavity, based on an acceleration cavity pattern stored in a first pattern memory and the acceleration cavity clock; and a deflection electromagnet control unit that controls a deflection electromagnet, based on a deflection electromagnet pattern stored in a second pattern memory and the electromagnet clock.
摘要翻译：目的是获得一种带电粒子加速器，其中用于操作基于时钟的加速腔和电磁体的模式数据量减少，并且模式数据通信时间缩短。在本发明的带电粒子加速器中设置的加速器控制装置的特征在于，包括：时钟生成部，其生成加速腔时钟;以及与加速腔时钟同步的电磁时钟，其频率比加速度腔钟; 基于存储在第一图案存储器中的加速腔图案和加速腔时钟控制加速腔的高频控制单元; 以及基于存储在第二图案存储器中的偏转电磁体图案和电磁时钟来控制偏转电磁体的偏转电磁体控制单元。

8. 发明授权

US08586942B2 Beam position monitor and particle beam therapy system 有权
标题翻译：梁位置监视器和粒子束治疗系统
公开(公告)号：US08586942B2
公开(公告)日：2013-11-19
申请号：US13639998
申请日：2012-01-20
申请人： Taizo Honda , Hisashi Harada , Yuehu Pu , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Yukiko Yamada
发明人： Taizo Honda , Hisashi Harada , Yuehu Pu , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Yukiko Yamada
IPC分类号： H01J3/10
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1071 , A61N2005/1074 , A61N2005/1087 , G01T1/29 , G21K5/00 , G21K5/02
摘要： A charged particle beam position monitor is provided with a plurality of position monitors and a beam data processing device that performs calculation processing of the state of a charged particle beam, based on a plurality of signals outputted from the position monitors. The beam data processing device includes a plurality of channel data conversion units that perform AD conversion processing of the plurality of signals outputted from the position monitors; a position size processing unit, for each of the position monitors, that calculates the beam position of the beam, based on voltage information obtained through the AD conversion processing; and an integrated control unit that controls the plurality of channel data conversion units in such a way that while the beam is irradiated onto an irradiation subject, AD conversion processing of the signals is performed at different timings for the respective position monitors.
摘要翻译：带电粒子束位置监视器具有多个位置监视器和根据从位置监视器输出的多个信号执行带电粒子束的状态的计算处理的波束数据处理装置。所述波束数据处理装置包括对从所述位置监视器输出的所述多个信号进行AD转换处理的多个信道数据变换部; 基于通过AD转换处理获得的电压信息，对位置监视器中的每一个计算光束位置的位置尺寸处理单元; 以及集成控制单元，其以这样的方式控制多个通道数据转换单元，即当将光束照射到照射对象时，对于各个位置监视器，在不同的定时执行信号的AD转换处理。

9. 发明申请

US20130274538A1 PARTICLE BEAM IRRADIATION APPARATUS AND PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：颗粒光束辐射装置和颗粒束治疗系统
公开(公告)号：US20130274538A1
公开(公告)日：2013-10-17
申请号：US13977058
申请日：2011-03-07
申请人： Yukiko Yamada , Hisashi Harada , Takaaki Iwata , Toshihiro Otani , Masahiro Ikeda , Kazushi Hanakawa , Taizo Honda
发明人： Yukiko Yamada , Hisashi Harada , Takaaki Iwata , Toshihiro Otani , Masahiro Ikeda , Kazushi Hanakawa , Taizo Honda
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1075 , A61N2005/1087 , G21K1/093
摘要： The particle beam irradiation apparatus comprises: a position monitor that detects a passing position of a charged particle beam; and an irradiation control apparatus that calculates a distance from a predetermined reference point to the position monitor, calculates a beam irradiation position on an irradiation subject, and controls irradiation of the beam; wherein the irradiation control apparatus includes a position calculation apparatus that calculates the beam irradiation position, based on a beam position detected by the position monitor, a scanning starting point distance information on a distance from a irradiation plane of the irradiation subject to a scanning starting point, of the beam, in a scanning electromagnet, and a position monitor distance information on a distance, from the irradiation plane to the position monitor, that is calculated based on the calculated distance.
摘要翻译：粒子束照射装置包括：位置监视器，其检测带电粒子束的通过位置; 以及照射控制装置，其计算从预定基准点到所述位置监视器的距离，计算照射对象的光束照射位置，并控制所述光束的照射; 其特征在于，所述照射控制装置包括：位置计算装置，其基于由所述位置监视器检测到的光束位置计算所述光束照射位置;从所述照射对象的照射面到扫描开始点的距离的扫描开始点距离信息，扫描电磁体中的距离信息，以及从照射平面到位置监视器的基于计算出的距离计算的位置监视距离信息。

10. 发明申请

US20130190548A1 BEAM POSITION MONITOR AND PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：光束位置监测器和粒子束治疗系统
公开(公告)号：US20130190548A1
公开(公告)日：2013-07-25
申请号：US13639998
申请日：2012-01-20
申请人： Taizo Honda , Hisashi Harada , Yuehu Pu , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Yukiko Yamada
发明人： Taizo Honda , Hisashi Harada , Yuehu Pu , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Yukiko Yamada
IPC分类号： A61N5/10 , G21K5/00
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1071 , A61N2005/1074 , A61N2005/1087 , G01T1/29 , G21K5/00 , G21K5/02
摘要： A charged particle beam position monitor is provided with a plurality of position monitors and a beam data processing device that performs calculation processing of the state of a charged particle beam, based on a plurality of signals outputted from the position monitors. The beam data processing device includes a plurality of channel data conversion units that perform AD conversion processing of the plurality of signals outputted from the position monitors; a position size processing unit, for each of the position monitors, that calculates the beam position of the beam, based on voltage information obtained through the AD conversion processing; and an integrated control unit that controls the plurality of channel data conversion units in such a way that while the beam is irradiated onto an irradiation subject, AD conversion processing of the signals is performed at different timings for the respective position monitors.
摘要翻译：带电粒子束位置监视器具有多个位置监视器和根据从位置监视器输出的多个信号执行带电粒子束的状态的计算处理的波束数据处理装置。所述波束数据处理装置包括对从所述位置监视器输出的所述多个信号进行AD转换处理的多个信道数据变换部; 基于通过AD转换处理获得的电压信息，对位置监视器中的每一个计算光束位置的位置尺寸处理单元; 以及集成控制单元，其以这样的方式控制多个通道数据转换单元，即当将光束照射到照射对象时，对于各个位置监视器，在不同的定时执行信号的AD转换处理。

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