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1. 发明授权

US08433115B2 System and method for multi-image based stent visibility enhancement 有权
标题翻译：用于基于多图像的支架可见度增强的系统和方法
公开(公告)号：US08433115B2
公开(公告)日：2013-04-30
申请号：US12846273
申请日：2010-07-29
申请人： Yunqiang Chen , Ti-chiun Chang , Michelle Xiaohong Yan , Tong Fang , Thomas Pohl , Stefan Böhm , Peter Durlak , Markus Roβmeier
发明人： Yunqiang Chen , Ti-chiun Chang , Michelle Xiaohong Yan , Tong Fang , Thomas Pohl , Stefan Böhm , Peter Durlak , Markus Roβmeier
IPC分类号： G06K9/00
CPC分类号： G06K9/6206 , G06K2209/057 , G06T5/001 , G06T5/20 , G06T5/50 , G06T2207/10016 , G06T2207/10121 , G06T2207/30101
摘要： A method for enhancing stent visibility in digital medical images includes providing a time series of 2-dimensional (2D) images of a stent in a vessel, estimating motion of the stent in a subset of images of the time series of images, estimating motion of clutter in the subset of images, where clutter comprises anatomical structures other than the stent, estimating a clutter layer in the subset of images from the estimated clutter motion, estimating a stent layer in the subset of images from the clutter layer and the estimated clutter motion, and minimizing a functional of the estimated stent motion, the estimated stent layer, the estimated clutter motion, and the estimated clutter layer to in calculate a refined stent layer image, where the refined stent layer image has enhanced visibility of the stent.
摘要翻译：一种用于增强数字医学图像中的支架可视性的方法包括在血管中提供支架的二维（2D）图像的时间序列，估计支架在时间序列图像的图像的子集中的运动，估计运动在图像子集中混乱，其中杂波包括除了支架之外的解剖结构，从估计的杂波运动估计图像子集中的杂波层，估计来自杂波层的图像子集中的支架层和估计的杂波运动并且在计算精制的支架层图像时，将精确的支架层图像具有增强的支架的可视性，并且将估计的支架运动，估计的支架层，估计的杂波运动和估计的杂波层的功能最小化。

2. 发明授权

US08411927B2 Marker detection in X-ray images 失效
标题翻译： X射线图像中的标记检测
公开(公告)号：US08411927B2
公开(公告)日：2013-04-02
申请号：US12898018
申请日：2010-10-05
申请人： Ti-chiun Chang , Yunqiang Chen , Michelle xiaohong Yan , Tong Fang
发明人： Ti-chiun Chang , Yunqiang Chen , Michelle xiaohong Yan , Tong Fang
IPC分类号： G06K9/00
CPC分类号： G06K9/00 , G06K2209/057 , G06T7/73 , G06T2207/10016 , G06T2207/10121 , G06T2207/30004 , G06T2207/30204
摘要： A method for detecting markers within X-ray images includes applying directional filters to a sequence of X-ray image frames. Marker candidate pixels are determined based on the output of the directional filters. Candidate pixels are grouped into clusters and distances between each possible pair of clusters is determined and the most frequently occurring distance is considered an estimated distance between markers. A first marker is detected at the cluster that most closely resembles a marker based on certain criteria and a second marker is then detected at a cluster that is the estimated distance from the first marker. The pair of first and second marker detections is scored to determine detection quality. If the detected marker pair has an acceptable score then the detected marker pair is used.
摘要翻译：用于检测X射线图像内的标记的方法包括对X射线图像帧序列应用方向滤波器。基于方向滤波器的输出来确定标记候选像素。候选像素被分组成簇，并且确定每个可能的一对簇之间的距离，并且将最常发生的距离视为标记之间的估计距离。基于某些标准，在最接近类似于标记的群集处检测到第一标记，然后在作为距离第一标记的估计距离的群集处检测到第二标记。对一对第一和第二标记检测进行评分以确定检测质量。如果检测到的标记对具有可接受的分数，则使用检测到的标记对。

3. 发明申请

US20120134553A1 Spatio-Temporal Analysis for Automatic Contrast Injection Detection on Angiography During Trans-Catheter Aortic Valve Implantation 有权
标题翻译：跨导管主动脉瓣植入时血管造影自动对比注射检测的时空分析
公开(公告)号：US20120134553A1
公开(公告)日：2012-05-31
申请号：US13283793
申请日：2011-10-28
申请人： Rui Liao , Michelle Xiaohong Yan , Wei You
发明人： Rui Liao , Michelle Xiaohong Yan , Wei You
IPC分类号： G06K9/00
CPC分类号： G06T7/0016 , G06K2209/05 , G06T2207/10121 , G06T2207/30104
摘要： A method that includes generating a contrast feature curve for a medical image sequence including a plurality of frames, where the contrast feature curve represents contrast feature values of the frames. The method further includes detecting a peak in the contrast feature curve, and determining whether the peak corresponds to at least one of contrast injection in an aortic root, contrast injection in a balloon, and a non-contrast injected region.
摘要翻译：一种方法，其包括生成包括多个帧的医学图像序列的对比度特征曲线，其中所述对比度特征曲线表示所述帧的对比特征值。该方法还包括检测对比度特征曲线中的峰值，以及确定该峰值是否对应于主动脉根部中的对比度注入，气球中的对比度注入和非对比度注入区域中的至少一种。

4. 发明授权

US08520924B2 Spatio-temporal analysis for automatic contrast injection detection on angiography during trans-catheter aortic valve implantation 有权
标题翻译：跨导管主动脉瓣植入期间血管造影自动造影剂检测的时空分析
公开(公告)号：US08520924B2
公开(公告)日：2013-08-27
申请号：US13283793
申请日：2011-10-28
申请人： Rui Liao , Michelle Xiaohong Yan , Wei You
发明人： Rui Liao , Michelle Xiaohong Yan , Wei You
IPC分类号： G06K9/00 , A61B5/02
CPC分类号： G06T7/0016 , G06K2209/05 , G06T2207/10121 , G06T2207/30104
摘要： A method that includes generating a contrast feature curve for a medical image sequence including a plurality of frames, where the contrast feature curve represents contrast feature values of the frames. The method further includes detecting a peak in the contrast feature curve, and determining whether the peak corresponds to at least one of contrast injection in an aortic root, contrast injection in a balloon, and a non-contrast injected region.
摘要翻译：一种方法，其包括生成包括多个帧的医学图像序列的对比度特征曲线，其中所述对比度特征曲线表示所述帧的对比特征值。该方法还包括检测对比度特征曲线中的峰值，以及确定该峰值是否对应于主动脉根部中的对比度注入，气球中的对比度注入和非对比度注入区域中的至少一种。

5. 发明授权

US08655041B2 Automatic detection of contrast injection 有权
标题翻译：自动检测造影剂注射
公开(公告)号：US08655041B2
公开(公告)日：2014-02-18
申请号：US13211716
申请日：2011-08-17
申请人： Matthias John , Rui Liao , Michelle xiaohong Yan , Wei You
发明人： Matthias John , Rui Liao , Michelle xiaohong Yan , Wei You
IPC分类号： G06K9/00
CPC分类号： G06T7/0014 , A61B6/481 , A61B6/487 , A61B6/504 , G06T2207/10121 , G06T2207/30048 , G06T2207/30101
摘要： A method for automatically detecting the presence of contrast in an x-ray image includes acquiring an x-ray image prior to administration of contrast. A background image is estimated based on the x-ray image. The contrast is administered. A set of x-ray images is acquired. The background image is subtracted from the set of images. Image intensity is determined for each of the subtracted images. The subtracted images having highest image intensity are selected. A predefined shape model is fitted to the selected subtracted images. The fitting of the predefined shape model is used to fit the shape model to each of the subtracted images. A feature value is calculated for each image frame based on pixel intensities of each pixel fitted to the shape model for the corresponding subtracted image. An image frame of peak contrast is determined by selecting the image frame with the greatest feature value.
摘要翻译：用于自动检测x射线图像中的对比度的存在的方法包括在施加对比度之前获取X射线图像。基于x射线图像估计背景图像。对比度被管理。获取一组X射线图像。从图像集中减去背景图像。确定每个减影图像的图像强度。选择具有最高图像强度的减影图像。预定义的形状模型适合于所选择的减影图像。使用预定义形状模型的拟合来将形状模型拟合到每个相减图像。基于适合于相应减法图像的形状模型的每个像素的像素强度，针对每个图像帧计算特征值。通过选择具有最大特征值的图像帧来确定峰值对比度的图像帧。

6. 发明申请

US20110103674A1 MARKER DETECTION IN X-RAY IMAGES 失效
标题翻译： X射线图像中的标记检测
公开(公告)号：US20110103674A1
公开(公告)日：2011-05-05
申请号：US12898018
申请日：2010-10-05
申请人： Ti-chiun Chang , Yunqiang Chen , Michelle xiaohong Yan , Tong Fang
发明人： Ti-chiun Chang , Yunqiang Chen , Michelle xiaohong Yan , Tong Fang
IPC分类号： G06K9/00
CPC分类号： G06K9/00 , G06K2209/057 , G06T7/73 , G06T2207/10016 , G06T2207/10121 , G06T2207/30004 , G06T2207/30204
摘要： A method for detecting markers within X-ray images includes applying directional filters to a sequence of X-ray image frames. Marker candidate pixels are determined based on the output of the directional filters. Candidate pixels are grouped into clusters and distances between each possible pair of clusters is determined and the most frequently occurring distance is considered an estimated distance between markers. A first marker is detected at the cluster that most closely resembles a marker based on certain criteria and a second marker is then detected at a cluster that is the estimated distance from the first marker. The pair of first and second marker detections is scored to determine detection quality. If the detected marker pair has an acceptable score then the detected marker pair is used.
摘要翻译：用于检测X射线图像内的标记的方法包括对X射线图像帧序列应用方向滤波器。基于方向滤波器的输出来确定标记候选像素。候选像素被分组成簇，并且确定每个可能的一对簇之间的距离，并且将最常发生的距离视为标记之间的估计距离。基于某些标准，在最接近类似于标记的群集处检测到第一标记，然后在作为距离第一标记的估计距离的群集处检测到第二标记。对一对第一和第二标记检测进行评分以确定检测质量。如果检测到的标记对具有可接受的分数，则使用检测到的标记对。

7. 发明授权

US09918700B2 Tuning ultrasound acquisition parameters 有权
公开(公告)号：US09918700B2
公开(公告)日：2018-03-20
申请号：US13928763
申请日：2013-06-27
申请人： Noha Youssry El-Zehiry , Michelle xiaohong Yan , Sara Good , Leo Grady
发明人： Noha Youssry El-Zehiry , Michelle xiaohong Yan , Sara Good , Leo Grady
IPC分类号： G06F19/00 , A61B8/00 , A61B8/08
CPC分类号： A61B8/54 , A61B8/5223 , A61B8/585 , G06F19/00 , G06F19/321 , G16H30/20 , G16H40/63 , G16H50/20
摘要： Values for ultrasound acquisition parameters are altered in a manifold space. The number of parameters to be set is reduced using a manifold. Virtual parameters different than the acquisition parameters are used to alter the greater number of acquisition parameters. In a further use, optimum image settings may be obtained in an automated system by measuring image quality for feeding back to virtual parameter adjustment.

8. 发明授权

US09702768B2 Noise robust time of flight estimation for acoustic pyrometry 有权
公开(公告)号：US09702768B2
公开(公告)日：2017-07-11
申请号：US13961292
申请日：2013-08-07
申请人： Heiko Claussen , Justinian Rosca , Michelle Xiaohong Yan , Upul P. DeSilva , Nancy H. Ulerich
发明人： Heiko Claussen , Justinian Rosca , Michelle Xiaohong Yan , Upul P. DeSilva , Nancy H. Ulerich
IPC分类号： G01K11/24 , G01K13/02
CPC分类号： G01K11/24 , G01K13/02 , G01K2013/024
摘要： An acoustic signal traversing a hot gas is sampled at a source and a receiver and is represented in overlapping windows that maximize useable signal content. Samples in each window are processed to represented in different sparsified bins in the frequency domain. Determining a signal delay between the source and the receiver from a summation of maximum smoothed coherence transform cross-correlation values of different data windows wherein a sparseness of a mean smoothed coherence transform cross-correlation of windows is maximized. Determining a set of delay times wherein outliers are deleted to estimate a time of flight from which a temperature of the hot gas is calculated.

9. 发明申请

US20150063411A1 NON-INTRUSIVE MEASURMENT OF HOT GAS TEMPERATURE IN A GAS TURBINE ENGINE 有权
标题翻译：燃气涡轮发动机热气温度的非调节性测量
公开(公告)号：US20150063411A1
公开(公告)日：2015-03-05
申请号：US14017386
申请日：2013-09-04
申请人： Upul P. DeSilva , Heiko Claussen , Michelle Xiaohong Yan , Justinian Rosca , Nancy H. Ulerich
发明人： Upul P. DeSilva , Heiko Claussen , Michelle Xiaohong Yan , Justinian Rosca , Nancy H. Ulerich
IPC分类号： G01M15/14 , G01K13/02 , G01H3/00 , F02C7/32
CPC分类号： G01M15/14 , F02C7/32 , F05D2260/83 , G01H3/00 , G01K11/24 , G01K13/02 , G01K2013/024
摘要： A method and apparatus for operating a gas turbine engine including determining a temperature of a working gas at a predetermined axial location within the engine. An acoustic signal is encoded with a distinct signature defined by a set of predetermined frequencies transmitted as a non-broadband signal. Acoustic signals are transmitted from an acoustic transmitter located at a predetermined axial location along the flow path of the gas turbine engine. A received signal is compared to one or more transmitted signals to identify a similarity of the received signal to a transmitted signal to identify a transmission time for the received signal. A time-of-flight is determined for the signal and the time-of-flight for the signal is processed to determine a temperature in a region of the predetermined axial location.
摘要翻译：一种用于操作燃气涡轮发动机的方法和装置，包括确定发动机内预定轴向位置处的工作气体的温度。声信号用由作为非宽带信号发送的一组预定频率定义的不同签名编码。声音信号从位于燃气涡轮发动机的流路的预定轴向位置处的声发射器发射。将接收到的信号与一个或多个发射信号进行比较，以识别接收到的信号与发射信号的相似性，以识别接收信号的传输时间。确定信号的飞行时间，并处理信号的飞行时间以确定预定轴向位置的区域中的温度。

10. 发明申请

US20140221832A1 TUNING ULTRASOUND ACQUISITION PARAMETERS 有权
标题翻译：调谐超声波采集参数
公开(公告)号：US20140221832A1
公开(公告)日：2014-08-07
申请号：US13928763
申请日：2013-06-27
申请人： Noha Youssry El-Zehiry , Michelle xiaohong Yan , Sara Good , Leo Grady
发明人： Noha Youssry El-Zehiry , Michelle xiaohong Yan , Sara Good , Leo Grady
IPC分类号： A61B8/00
CPC分类号： A61B8/54 , A61B8/5223 , A61B8/585 , G06F19/00 , G06F19/321 , G16H30/20 , G16H40/63 , G16H50/20
摘要： Values for ultrasound acquisition parameters are altered in a manifold space. The number of parameters to be set is reduced using a manifold. Virtual parameters different than the acquisition parameters are used to alter the greater number of acquisition parameters. In a further use, optimum image settings may be obtained in an automated system by measuring image quality for feeding back to virtual parameter adjustment.
摘要翻译：超声波采集参数的值在歧管空间中改变。使用歧管减少要设置的参数数量。使用与采集参数不同的虚拟参数来改变更多的采集参数。在进一步的使用中，通过测量图像质量以反馈到虚拟参数调整，可以在自动化系统中获得最佳图像设置。

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