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1. 发明授权

US08731264B2 System and method for fusing real-time ultrasound images with pre-acquired medical images 有权
标题翻译：将实时超声图像与预先获取的医学图像融合的系统和方法
公开(公告)号：US08731264B2
公开(公告)日：2014-05-20
申请号：US12516407
申请日：2007-11-26
申请人： Jochen Kruecker , Sheng Xu , Neil David Glossop , Peter Lyle Choyke , Bradford J. Wood
发明人： Jochen Kruecker , Sheng Xu , Neil David Glossop , Peter Lyle Choyke , Bradford J. Wood
IPC分类号： G06K9/00
CPC分类号： A61B8/4254 , A61B8/4245 , G06T3/0081 , G06T7/30 , G06T2207/10068 , G06T2207/10072 , G06T2207/10132 , G06T2207/30004
摘要： A method, apparatus and system for fusing real-time ultrasound images with pre-acquired medical images are described.
摘要翻译：描述了将实时超声图像与预先获取的医学图像进行融合的方法，装置和系统。

2. 发明授权

US07840254B2 Electromagnetically tracked K-wire device 失效
标题翻译：电磁跟踪K线装置
公开(公告)号：US07840254B2
公开(公告)日：2010-11-23
申请号：US11333364
申请日：2006-01-18
申请人： Neil David Glossop
发明人： Neil David Glossop
IPC分类号： A61B5/05
CPC分类号： A61B90/36 , A61B34/20 , A61B90/39 , A61B90/94 , A61B90/96 , A61B90/98 , A61B2017/0046 , A61B2034/2051 , A61B2090/3975 , A61B2090/3983
摘要： Devices and methods for registering, dynamically referencing, and navigating an anatomical region of interest of a patient are provided using a tracked Kirschner wire (K-wire), where the K-wire includes a position-indicating element.
摘要翻译：使用跟踪的克氏针（K线）提供用于注册，动态地引用和导航患者感兴趣解剖区域的装置和方法，其中K线包括位置指示元件。

3. 发明授权

US5834759A Tracking device having emitter groups with different emitting directions 失效
标题翻译：具有不同发射方向的发射极组的跟踪装置
公开(公告)号：US5834759A
公开(公告)日：1998-11-10
申请号：US861597
申请日：1997-05-22
申请人： Neil David Glossop
发明人： Neil David Glossop
IPC分类号： G01S5/16 , G01J1/20
CPC分类号： G01S5/163
摘要： A tracking device for use in an optical tracking system is disclosed. The tracking device has a plurality of faces, each face having at least three markers which can be tracked by the optical tracking system. The markers may be infrared emitting diodes. The tracking system can individually activate the markers on each of the faces and select the markers which can be most accurately tracked by the tracking system. Portions of the faces are adjacent to one another to form clusters of emitters. The clusters of emitters are separated by at least a predetermined distance corresponding to the tolerance of the optical tracking system. The field of view of the tracking device approximates a section of a sphere centered at the device.
摘要翻译：公开了一种用于光学跟踪系统的跟踪装置。跟踪装置具有多个面，每个面具有至少三个可由光学跟踪系统跟踪的标记。标记可以是红外发射二极管。跟踪系统可以单独激活每个面上的标记，并选择跟踪系统可以最准确地跟踪的标记。面的一部分彼此相邻以形成发射体簇。发射体簇被分开至少一个对应于光学跟踪系统的公差的预定距离。跟踪装置的视野近似于以装置为中心的球体的一部分。

4. 发明授权

US10850126B2 System and method for guided adaptive brachytherapy 有权
公开(公告)号：US10850126B2
公开(公告)日：2020-12-01
申请号：US13703750
申请日：2011-05-27
申请人： Dirk Binnekamp , Luis Felipe Gutierrez , Neil David Glossop , Jochen Kruecker , Shriram Sethuraman
发明人： Dirk Binnekamp , Luis Felipe Gutierrez , Neil David Glossop , Jochen Kruecker , Shriram Sethuraman
IPC分类号： A61N5/10 , A61B5/06 , A61B6/02 , A61B8/12 , A61B34/20
摘要： A system and methods for adaptive placement of a treatment element include a placement device (134), and a localization system (120) configured to track progress of the placement device such that a position of a treatment element (146, 132) placed by or to be placed by the placement device is stored in memory. A computer system (142) includes a program (104) implemented in computer readable storage media and configured to compute an effect of the treatment element at the position and determine whether a dosage amount has been achieved by the treatment element for treatment of an organ.

5. 发明授权

US08948845B2 System, methods, and instrumentation for image guided prostate treatment 有权
标题翻译：图像引导前列腺治疗的系统，方法和仪器
公开(公告)号：US08948845B2
公开(公告)日：2015-02-03
申请号：US11694280
申请日：2007-03-30
申请人： Neil David Glossop , Bradford Johns Wood
发明人： Neil David Glossop , Bradford Johns Wood
IPC分类号： A61B5/05 , A61B19/00 , A61B8/08 , A61B8/00 , A61B17/3211 , A61B17/32 , A61B18/14 , A61B17/28
CPC分类号： A61B19/5244 , A61B8/0833 , A61B8/0841 , A61B8/4245 , A61B17/320092 , A61B17/3211 , A61B18/148 , A61B34/20 , A61B90/36 , A61B2017/2808 , A61B2034/2051 , A61B2090/365 , A61B2090/378 , A61B2090/3983
摘要： The invention provides systems, methods, and instrumentation for aiding the performance of an image guided procedure of the anatomy of a patient such as, for example, the prostate. The invention includes a plurality of lumens therein and a balloon portion or other fixating portion. In some embodiments, the catheter includes a lumen for introducing a contrast agent visible to an imaging modality external to the anatomy of the patient. Image space data of the catheter within the anatomy of the patient may be obtained using the imaging modality. The catheter also includes at least a lumen for inserting a registration device for obtaining patient space data regarding the anatomy of the patient. Other lumens and/or other elements visible to the imaging modality may be used. The image space data may be registered to the patient space data for use during an image guided procedure to the anatomy of the patient.
摘要翻译：本发明提供了用于帮助执行患者（例如前列腺）的解剖结构的图像引导过程的系统，方法和仪器。本发明在其中包括多个内腔和气球部分或其它固定部分。在一些实施例中，导管包括用于引入对患者解剖结构外部的成像模态可见的造影剂的内腔。可以使用成像模态获得患者解剖结构内的导管的图像空间数据。导管还包括至少一个用于插入用于获得关于患者的解剖结构的患者空间数据的注册装置的内腔。可以使用对成像模态可见的其它流明和/或其它元件。可以将图像空间数据登记到患者空间数据，以在对患者的解剖结构的图像引导过程中使用。

6. 发明授权

US07722565B2 Access system 有权
标题翻译：访问系统
公开(公告)号：US07722565B2
公开(公告)日：2010-05-25
申请号：US11718679
申请日：2005-11-04
申请人： Bradford Johns Wood , Neil David Glossop
发明人： Bradford Johns Wood , Neil David Glossop
IPC分类号： A61M5/00
CPC分类号： A61B17/3403 , A61B10/0233 , A61B90/11 , A61B2017/3411
摘要： The invention provides systems and methods for providing access to a target site. Example systems may include a needle, a grid to guide the needle, a plate with an aperture, a member coupled to the plate and including a semispherical surface, and a hub slideably coupled to the plate by a guide. The system may also include a needle coupled to the hub, the needle including a magnetically trackable sensor positioned in a tip of the needle. The semispherical surface can be positioned against skin of a body and the hub slid relative to the plate along the guide to insert the needle through the aperture in the plate into the body until the tip reaches a target site. The hub can be locked by a lock mechanism when the tip of the needle reaches the target site, and an action performed on the target site through the needle.
摘要翻译：本发明提供了用于提供对目标站点的访问的系统和方法。示例性系统可以包括针，引导针的网格，具有孔的板，联接到板并且包括半球形表面的构件以及通过引导件可滑动地联接到板的轮毂。该系统还可以包括联接到轮毂的针，该针包括位于针的尖端中的可磁性跟踪的传感器。半球形表面可以抵靠主体的皮肤定位，并且轮毂沿着引导件相对于板滑动，以将针穿过板中的孔插入体内，直到尖端到达目标部位。当针尖到达目标位置时，轮毂可以被锁定机构锁定，并且通过针头在目标部位上执行动作。

7. 发明授权

US08632461B2 System, method and apparatus for navigated therapy and diagnosis 有权
标题翻译：用于导航治疗和诊断的系统，方法和装置
公开(公告)号：US08632461B2
公开(公告)日：2014-01-21
申请号：US11471604
申请日：2006-06-21
申请人： Neil David Glossop
发明人： Neil David Glossop
IPC分类号： A61B17/00 , A61B1/00 , A61B5/05
CPC分类号： A61B1/018 , A61B5/064 , A61B5/065 , A61B10/0275 , A61B10/06 , A61B17/32056 , A61B18/18 , A61B18/22 , A61B34/20 , A61B90/36 , A61B2034/2051 , A61B2090/378 , A61B2090/3975 , A61B2090/3983
摘要： The invention provides an image-guided medical instrument that utilizes a tracking device to track the location of at least a portion of the instrument on at least one image of a patient's anatomy. The instrument may include a handle having an operating element, an elongated flexible body member connected to the handle, wherein the body member includes a lumen, a transmission element housed within the lumen of the body member, and a treatment apparatus connected to end of the transmission element, wherein actuation of the operating element actuates the treatment apparatus via the transmission element. The body member also includes at least one sensor element that is utilized by the tracking device to determine position information regarding the treatment apparatus that is used to display the location of the treatment apparatus on the at least one image of the patient's anatomy.
摘要翻译：本发明提供了一种图像引导医疗仪器，其利用跟踪装置来跟踪至少一部分仪器在患者解剖结构的至少一个图像上的位置。仪器可以包括具有操作元件的手柄，连接到手柄的细长的柔性本体构件，其中主体构件包括内腔，容纳在主体构件的内腔内的传动元件，以及连接到主体构件的端部的处理装置传动元件，其中操作元件的致动通过传动元件致动治疗装置。主体构件还包括至少一个传感器元件，其被跟踪装置用于确定关于治疗装置的位置信息，所述位置信息用于将治疗装置的位置显示在患者解剖结构的至少一个图像上。

8. 发明授权

US08611983B2 Method and apparatus for guiding an instrument to a target in the lung 有权
标题翻译：用于将仪器引导到肺中的靶标的方法和装置
公开(公告)号：US08611983B2
公开(公告)日：2013-12-17
申请号：US11333363
申请日：2006-01-18
申请人： Neil David Glossop
发明人： Neil David Glossop
IPC分类号： A61B5/05
CPC分类号： A61M25/0136 , A61B1/2676 , A61B34/20 , A61B90/36 , A61B2017/0034 , A61B2017/00694 , A61B2017/00809 , A61B2017/22038 , A61B2034/2051 , A61M25/00 , A61M25/0113 , A61M25/0133 , A61M2025/09191
摘要： The invention provides methods and apparatus for navigating a medical instrument to a target in the lung. In one embodiment, the invention includes inserting a bronchoscope into the lung, inserting a catheter into the lung through the working channel of the bronchoscope, inserting a tracked navigation instrument wire into the lung through the catheter, navigating the tracked navigation instrument through the lung to the target, advancing the catheter over the tracked navigation instrument to the target, removing the tracked navigation instrument from the catheter, and inserting a medical instrument into the catheter, thus bringing the medical instrument in proximity to the target.
摘要翻译：本发明提供了用于将医疗器械导航到肺中的靶标的方法和装置。在一个实施例中，本发明包括将支气管镜插入肺中，通过支气管镜的工作通道将导管插入肺中，通过导管将跟踪的导航仪器线插入到肺中，将跟踪的导航仪通过肺导航到将导管推进到跟踪的导航仪器上至目标，从导管中移除跟踪的导航仪器，并将医疗仪器插入导管中，从而使医疗器械靠近目标。

9. 发明授权

US07840251B2 Device and method for registering a position sensor in an anatomical body 有权
标题翻译：用于将位置传感器记录在解剖体内的装置和方法
公开(公告)号：US07840251B2
公开(公告)日：2010-11-23
申请号：US10928729
申请日：2004-08-30
申请人： Neil David Glossop
发明人： Neil David Glossop
IPC分类号： A61B5/05
CPC分类号： A61B90/36 , A61B34/20 , A61B90/39 , A61B2034/2051 , A61B2090/3983 , A61B2090/3987
摘要： An apparatus having an insertable portion for holding a position sensor is disclosed. The position sensor can transmit a signal indicative of its position with respect to a field generator. The insertable portion of the catheter has fiducial markings that are detectable by an imaging modality when the insertable portion is inserted into the anatomical body. The fiducial markings are asymmetrical about at least a first axis of the insertable portion. After the insertable portion has been inserted into the anatomical body, the fiducial markings can be detected to facilitate registration of the position sensor held in the insertable portion to the anatomical body. The apparatus also has a fixing mechanism for releasably fixing the insertable portion to the anatomical body. The non-symmetrical fiducial markings facilitate unambiguous registration of the insertable portion to the anatomical body. When the insertable portion is inserted into the anatomical body to a location of interest, the fixing mechanism substantially rigidly fixes the insertable portion of the catheter to a part of the anatomical body near the location of interest.
摘要翻译：公开了一种具有用于保持位置传感器的可插入部分的装置。位置传感器可以发送指示其相对于场发生器的位置的信号。导管的可插入部分具有当可插入部分插入到解剖体内时可通过成像模态检测的基准标记。基准标记关于可插入部分的至少第一轴线是不对称的。在可插入部分已经插入到解剖体中之后，可以检测基准标记，以便于将保持在可插入部分中的位置传感器对准到解剖体。该装置还具有用于将可插入部分可释放地固定到解剖体上的固定机构。非对称的基准标记促进可插入部分到解剖体的明确配准。当可插入部分插入到解剖体中到感兴趣的位置时，固定机构将导管的可插入部分基本上刚性地固定在感兴趣位置附近的解剖体的一部分上。

10. 发明授权

US06203543B1 Device for releasably securing objects to bones 有权
标题翻译：用于将物体可释放地固定到骨头的装置
公开(公告)号：US06203543B1
公开(公告)日：2001-03-20
申请号：US09336691
申请日：1999-06-21
申请人： Neil David Glossop
发明人： Neil David Glossop
IPC分类号： A61B1756
CPC分类号： A61B17/86 , A61B2017/8655 , A61B2090/035 , A61B2090/3916 , A61B2090/3983 , Y10S606/916
摘要： A device to releasably secure an object to a bone is disclosed. The device has a rotation restricting member which, while engaging the bone, prevents rotation of the member. The device also comprises an axial supporting member which axially secures the device to the bone, and preferably comprises a bone screw. While the bone screw and rotation restricting member engage the bone, a fastening mechanism fastens the rotation restricting member to the bone screw. In this way, objects can be releasably secured to the rotation restricting member or the bone screw by means of a clamp to temporarily axially and rotationally secure the objects to the bone. Preferably, the rotation restricting member comprises a sleeve and the fastening mechanism comprises a nut which engages threads on the bone screw. The sleeve comprises serrated teeth which, when biased towards the bone, engage the bone to restrict rotation of the sleeve. Rotation of the nut about the threads on the bone screw axially bias the sleeve towards the bone such that the serrated teeth engage the bone to restrict rotation of the sleeve about the screw and to fasten the sleeve to the bone screw.
摘要翻译：公开了将物体可释放地固定到骨骼上的装置。该装置具有旋转限制构件，该旋转限制构件在与骨骼接合时防止构件的旋转。该装置还包括轴向支撑构件，该轴向支撑构件将装置轴向地固定到骨头上，并且优选地包括骨螺钉。当骨螺钉和旋转限制构件接合骨时，紧固机构将旋转限制构件紧固到骨螺钉。以这种方式，物体可以通过夹具可释放地固定到旋转限制构件或骨螺钉，以临时轴向并将物体旋转地固定到骨骼上。优选地，旋转限制构件包括套筒，紧固机构包括接合骨螺钉上的螺纹的螺母。套筒包括锯齿状齿，当被朝向骨偏压时，它们接合骨头以限制套筒的旋转。螺母围绕骨螺钉上的螺纹的旋转将套筒轴向地朝向骨头偏置，使得锯齿形齿接合骨头以限制套筒围绕螺钉的旋转并将套筒紧固到骨螺钉。

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