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1. 发明申请

US20220203050A1 INHALER SYSTEM 有权
公开(公告)号：US20220203050A1
公开(公告)日：2022-06-30
申请号：US17607442
申请日：2020-04-30
申请人： Norton (Waterford) Limited
发明人： Mark Milton-Edwards , Guilherme Safioti , Lena Granovsky , Michael Reich
IPC分类号： A61M15/00 , G16H20/13
摘要： Provided is a system (10) for determining a probability of a CORD exacerbation in a subject. The system comprises a first inhaler (100) for delivering a rescue medicament to the subject. The rescue medicament may be suitable for treating the subject's acute respiratory disease, for example by effecting rapid dilation of the bronchi and bronchioles upon inhalation of the medicament. The first inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. The system optionally includes a second inhaler for delivering a maintenance medicament to the subject during a routine inhalation A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation and/or during the routine inhalation, when the second inhaler is included in the system. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue and/or routine inhalations. The processor then determines, using a weighted model, the probability of the CORD exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the parameters are more significant in the probability determination than the number of rescue inhalations. Further provided is a method for determining the probability of a COPD exacerbation in a subject, which method employs the weighted model.

2. 发明申请

US20220143337A1 INHALATION DEVICE WITH INTEGRATED ELECTRONICS 有权
公开(公告)号：US20220143337A1
公开(公告)日：2022-05-12
申请号：US17583792
申请日：2022-01-25
申请人： NORTON (WATERFORD) LIMITED
发明人： Dong Yang , Dylan A. Moorhouse
IPC分类号： A61M15/00
摘要： A device for delivering medication to a user may include a circular or elliptical body that include a mouthpiece, a flexible strip of medication, a lever, and a mouthpiece cover, where the mouthpiece cover is rotatable about the body. The electronics module may include a communication circuit, a sensor system, and a switch. The lever may be configured to actuate the switch when the lever is moved from a closed position to an open position. The lever is configured to advance a dose of medication on the flexible strip when moved from the closed position to the open position. When actuated, the switch may be configured to switch the electronics module from an off state to an active state wen the lever is actuated for a first time by a user. Thereafter, the electronics module is configured to not return to the off state.

3. 发明申请

US20210402111A1 INHALATION MONITORING SYSTEM AND METHOD 有权
公开(公告)号：US20210402111A1
公开(公告)日：2021-12-30
申请号：US17468928
申请日：2021-09-08
申请人： Norton (Waterford) Limited
发明人： Mark Milton-Edwards , Henry Chrystyn , Mark Steven Morrison , Douglas E. Weitzel
IPC分类号： A61M15/00 , A61B5/00 , A61M16/00 , G16H20/10 , G16Z99/00 , A61B5/087 , A61B5/091
摘要： An inhalation monitoring system includes an inhaler having a medicament delivery apparatus configured to deliver medicament to a user during an inhalation of the user; inhalation monitoring apparatus, configured to, during the inhalation, gather data for determining a measure of the user's lung function and/or lung health; and a processor configured to receive the data from the inhalation monitoring apparatus and, using the data, determine a measure of the user's lung function and/or lung health.

4. 发明申请

US20210393893A1 INHALER SYSTEM 有权
公开(公告)号：US20210393893A1
公开(公告)日：2021-12-23
申请号：US16906896
申请日：2020-06-19
申请人： Norton (Waterford) Limited
发明人： Xinyu Liu , Jenna-Leigh Meola , Cody Goldberg , Jinn Kim , Sunil Kumar Mishra , Vered Ben-Anat
IPC分类号： A61M15/00 , G16H20/13 , G06F21/60 , H04L29/06 , G06K7/14
摘要： Provided is a system comprising a plurality of inhalers that each include a processor configured to determine a value of a usage parameter relating to use of the respective first inhaler, encrypt data based on the value, and transmit the encrypted data. At least two of the inhalers include different medicament, such as a rescue medicament and a maintenance medicament. The system includes an external device that includes a processor configured to distinguish between the encrypted data of each respective inhaler, determine respective usage information relating to each of the distinct types of medicament based on the respective encrypted data, and control a user interface (e.g., of the external device) to communicate the usage information related to each inhaler and/or each respective type of medicament.

5. 发明授权

US11173259B2 Drug delivery device with electronics and power management 有权
公开(公告)号：US11173259B2
公开(公告)日：2021-11-16
申请号：US16921193
申请日：2020-07-06
申请人： Norton (Waterford) Limited
发明人： Enrique Calderon Oliveras , Amir Kesten
IPC分类号： A61M15/00
摘要： A system may limit the number of times an inhalation device transmits inhalation data to a single time to reduce the battery usage of the inhalation device. The system may include an inhalation device that has medicament and an electronics module. The system may limit the number of times the inhalation device transmits new inhalation data to any mobile device to a single time by causing the server to receive the new inhalation data from one of the mobile devices and causing the server to transmit the new inhalation data to other of the mobile devices prior to the other mobile devices transmitting a request for the new inhalation data to the inhalation device. The inhalation device may include a Quick Response (QR) code, and a mobile application may determine at least one of a medication type or a number of doses of the inhalation device from the QR code.

6. 发明申请

US20210293715A1 APPLICATION OF RAMAN SPECTROSCOPY FOR THE MANUFACTURE OF INHALATION POWDERS 有权
公开(公告)号：US20210293715A1
公开(公告)日：2021-09-23
申请号：US17266884
申请日：2019-08-07
申请人： NORTON (WATERFORD) LIMITED
发明人： Hardik Kirtikumar SHAH
IPC分类号： G01N21/65 , A61K45/06 , A61K9/00 , G01N21/85 , G01J3/44 , A61K31/567 , A61K31/138
摘要： The present invention generally relates to improved methods for the manufacture of inhalation powders. More particularly, aspects of the disclosure relate to methods for in-line monitoring of powder blending by Raman spectroscopy.

7. 发明申请

US20210138167A1 COMPLIANCE MONITORING MODULE FOR A BREATH-ACTUATED INHALER 有权
公开(公告)号：US20210138167A1
公开(公告)日：2021-05-13
申请号：US17156080
申请日：2021-01-22
申请人： Norton (Waterford) Limited
发明人： Mark Steven Morrison , Douglas E. Weitzel , Enrique Calderon Oliveras , Daniel Buck
IPC分类号： A61M15/00
摘要： A compliance monitoring module for a breath-actuated inhaler comprising: a miniature pressure sensor, a sensor port of said sensor being pneumatically coupled to a flow channel through which a user can inhale; a processor configured to: receive a signal originating from a dosing mechanism of the inhaler indicating that medication has been released; receive data from a sensing element of the sensor; and based on said signal from said dosing mechanism and said data from said sensing element, make a determination that inhalation of a breath containing medication through said flow channel complies with one or more predetermined requirements for successful dosing; and a transmitter configured to, responsive to said determination, issue a dosing report.

8. 发明授权

US10695512B2 Dose counter for inhaler having an anti-reverse rotation actuator 有权
公开(公告)号：US10695512B2
公开(公告)日：2020-06-30
申请号：US15804735
申请日：2017-11-06
申请人： Ivax Pharmaceuticals Ireland , Norton (Waterford) Limited , Teva Pharmaceuticals Ireland
发明人： Declan Walsh , Derek Fenlon , Simon Kaar , Jan Geert Hazenberg , Daniel Buck , Paul Clancy , Robert Charles Uschold , Jeffrey A. Karg
IPC分类号： A61M15/00 , G06M1/24 , A61M11/00
摘要： An inhaler includes a main body having a canister housing, a medicament canister retained in a central outlet port of the canister housing, and a dose counter having an actuation member for operation by movement of the medicament canister. The canister housing has an inner wall, and a first inner wall canister support formation extending inwardly from a main surface of the inner wall. The canister housing has a longitudinal axis X which passes through the center of the central outlet port. The first inner wall canister support formation, the actuation member, and the central outlet port lie in a common plane coincident with the longitudinal axis X such that the first inner wall canister support formation protects against unwanted actuation of the dose counter by reducing rocking of the medicament canister relative to the main body of the inhaler.

9. 发明授权

US10569034B2 Compliance monitoring module for a breath-actuated inhaler 有权
公开(公告)号：US10569034B2
公开(公告)日：2020-02-25
申请号：US15681126
申请日：2017-08-18
申请人： Norton (Waterford) Limited
发明人： Mark Steven Morrison , Douglas E. Weitzel , Enrique Calderon Oliveras , Daniel Buck
IPC分类号： A61M15/00
摘要： A compliance monitoring module for a breath-actuated inhaler comprising: a miniature pressure sensor, a sensor port of said sensor being pneumatically coupled to a flow channel through which a user can inhale; a processor configured to: receive a signal originating from a dosing mechanism of the inhaler indicating that medication has been released; receive data from a sensing element of the sensor; and based on said signal from said dosing mechanism and said data from said sensing element, make a determination that inhalation of a breath containing medication through said flow channel complies with one or more predetermined requirements for successful dosing; and a transmitter configured to, responsive to said determination, issue a dosing report.

10. 外观设计

USD853555S1 Inhaler 有权
公开(公告)号：USD853555S1
公开(公告)日：2019-07-09
申请号：US29589565
申请日：2017-01-03
申请人： Norton (Waterford) Limited
设计人： Enrique Calderon Oliveras , James Roche

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