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1. 发明授权

US11191473B1 Generation of vital sign monitoring 有权
公开(公告)号：US11191473B1
公开(公告)日：2021-12-07
申请号：US16595395
申请日：2019-10-07
申请人： Guangren Chen , Jia Li Chen , Rong Yang
发明人： Guangren Chen , Jia Li Chen , Rong Yang
IPC分类号： A61B5/364 , A61B5/316 , A61B5/366 , A61B5/339
摘要： Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients or to a set of rules developed from the database. A bundle branches (BB) to J-Point (BB-J) interval is identified from the plurality of subwaveforms and discontinuity points based on the comparison. The ECG waveform with the BB-J interval annotated is displayed.

2. 发明授权

US11179388B2 Topical composition for treating rosacea and a method for treating rosacea with the same 有权
公开(公告)号：US11179388B2
公开(公告)日：2021-11-23
申请号：US16616444
申请日：2018-05-25
申请人： Scott Whitcup , Rong Yang , Jinsong Ni
发明人： Scott Whitcup , Rong Yang , Jinsong Ni
IPC分类号： A61K31/496 , A61K31/4164 , A61K31/135 , A61P17/00 , A61K31/44 , A61K9/00
摘要： A composition for use in the treatment of rosacea includes a multi-kinase inhibitor that inhibits both a Vascular Endothelial Growth Factor Receptor and a Fibroblast Growth Factor Receptor. A method for treating rosacea for a patient includes inhibiting a Vascular Endothelial Growth Factor Receptor of the patient; and inhibiting a Fibroblast Growth Factor Receptor of the patient.

3. 发明授权

US10835617B2 VEGF antibody-drug conjugates 有权
公开(公告)号：US10835617B2
公开(公告)日：2020-11-17
申请号：US16072415
申请日：2017-02-02
申请人： Jinsong Ni , Rong Yang
发明人： Jinsong Ni , Rong Yang
IPC分类号： A61K47/68 , A61K39/395 , C07K16/22 , A61K9/08 , A61K9/00 , C07K16/00 , A61K31/496 , A61K47/46
CPC分类号： A61K47/6845 , A61K9/0048 , A61K9/08 , A61K31/496 , A61K39/3955 , A61K47/6803 , A61K47/6849 , C07K16/00 , C07K16/22 , A61K47/46 , C07K2317/24
摘要： A method of producing synergistic and enhanced efficacy in treating a disease in a subject includes providing an antibody, the antibody being a classic antibody or a modified biologic molecule that blocks a first target in the subject; providing a drug, the drug being a small molecule agent that blocks the first target or a second target in the subject; connecting the antibody and the drug with a linker to form an Antibody-Drug Synergism (ADS) compound; and treating the disease with the ADS compound. The linker is hydrolyzed in the subject over a certain time so that both the antibody and the drug exert their functions simultaneously, and the ADS compound confers better efficacy than either the antibody or the drug alone due to a synergism of the ADS compound.

4. 发明授权

US10327574B2 Anti-loose thermal insulation cup sleeve with reverse damping structure 有权
公开(公告)号：US10327574B2
公开(公告)日：2019-06-25
申请号：US15639726
申请日：2017-06-30
申请人： Tai-Her Yang , Chun-Rong Yang
发明人： Tai-Her Yang , Chun-Rong Yang
IPC分类号： A47G23/02
摘要： The present invention provides a cup sleeve formed with a reverse damping structure having one or more rings inwardly bent and annularly arranged on one or both of the edge and the inner periphery of the cup sleeve, so when the mentioned cup sleeve is sleeved with a cup-shaped or bottle-shaped or can-shaped container, the anti-slip damping for enhancing the anti-loose function is provided by the reverse damping structure, thus the cup sleeve is less likely to be released from the cup-shaped or bottle-shaped or can-shaped container, and with the reverse damping structure, the interval formed between the cup sleeve and the cup-shaped or bottle-shaped or can-shaped container is enlarged thereby increasing the thermal insulation effect.

5. 发明申请

US20180235497A1 Accurate ECG I-Point and J-Joint Detection and Measurement 审中-公开
公开(公告)号：US20180235497A1
公开(公告)日：2018-08-23
申请号：US15961952
申请日：2018-04-25
申请人： Guangren Chen , Rong Yang , Zhongnong Jiang
发明人： Guangren Chen , Rong Yang , Zhongnong Jiang
IPC分类号： A61B5/0402 , A61B5/04 , A61B5/044 , A61B5/00 , A61B5/0245
CPC分类号： A61B5/04023 , A61B5/0245 , A61B5/04014 , A61B5/044 , A61B5/6823
摘要： An ECG system measures and annotates the I-point of in an ECG waveform from harmonic waveforms. Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients. A discontinuity point is identified as the I-point of the ECG waveform from the comparison. The ECG waveform is displayed along with a marker at a location of the discontinuity point.

6. 发明申请

US20150261234A1 REFERENCE POWER GENERATING CIRCUIT AND ELECTRONIC CIRCUIT USING THE SAME 有权
标题翻译：参考发电电路和使用该发电电路的电子电路
公开(公告)号：US20150261234A1
公开(公告)日：2015-09-17
申请号：US14287064
申请日：2014-05-26
申请人： Muh-Rong Yang
发明人： Muh-Rong Yang
IPC分类号： G05F1/46
CPC分类号： G05F1/468 , G05F3/30
摘要： A reference power generating circuit and an electronic circuit using the same are provided. The reference power generating circuit includes a first bandgap reference circuit and a second bandgap reference circuit. The first bandgap reference circuit is biased by a power voltage to generate a first reference voltage, where the first reference voltage has a first offset. The second bandgap reference circuit is connected to the first bandgap reference circuit in series and receives the first reference voltage generated by the first bandgap reference circuit. The second bandgap reference circuit is biased by the first reference voltage to generate a baseline reference voltage. The baseline reference voltage has a second offset, and the second offset is smaller than the first offset.
摘要翻译：提供了参考功率发生电路和使用其的电子电路。参考功率产生电路包括第一带隙基准电路和第二带隙基准电路。第一带隙参考电路被电源电压偏置以产生第一参考电压，其中第一参考电压具有第一偏移。第二带隙基准电路串联连接到第一带隙基准电路，并接收由第一带隙基准电路产生的第一参考电压。第二带隙基准电路被第一参考电压偏置以产生基准参考电压。基准参考电压具有第二偏移，第二偏移小于第一偏移。

7. 发明授权

US08764001B2 Supporting apparatus for display assembly 失效
标题翻译：显示器组装支撑装置
公开(公告)号：US08764001B2
公开(公告)日：2014-07-01
申请号：US13527666
申请日：2012-06-20
申请人： Chih-Hao Yang , Bao-Quan Shi , Rong Yang
发明人： Chih-Hao Yang , Bao-Quan Shi , Rong Yang
IPC分类号： B23Q3/00 , B25B5/16 , B25B1/24 , B23Q1/00 , B25B11/02
CPC分类号： B25B11/02
摘要： A supporting apparatus for assembling a display, includes a supporting bracket. The supporting bracket includes a plate and a restricting arm connected to the plate. The restricting arm includes a connection portion and a restricting portion the restricting. The restricting portion is parallel to the plate to define a restricting space between the restricting portion and the plate. The restricting space receives the display therein. The restricting portion and the plate restricts the display in the restricting space in a first direction which is perpendicular to the plate. A plurality of blocks are movably mounted on the plate. The plurality of blocks restrict the display in the restrict space in a second direction which is parallel to the plate.
摘要翻译：一种用于组装显示器的支撑装置，包括支撑托架。支撑托架包括连接到板的板和限制臂。限制臂包括连接部分和限制部分。限制部分平行于板以限定限制部分和板之间的限制空间。限制空间在其中接收显示。限制部分和板限制在与板平行的第一方向上的限制空间中的显示。多个块可移动地安装在板上。多个块在与板平行的第二方向上限制限制空间中的显示。

8. 发明申请

US20130155624A1 HEAT DISSIPATION STRUCTURE 失效
标题翻译：散热结构
公开(公告)号：US20130155624A1
公开(公告)日：2013-06-20
申请号：US13456498
申请日：2012-04-26
申请人： CHIH-HAO YANG , BAO-QUAN SHI , RONG YANG , XIANG-KUN ZENG
发明人： CHIH-HAO YANG , BAO-QUAN SHI , RONG YANG , XIANG-KUN ZENG
IPC分类号： H05K7/20 , F28F7/00
CPC分类号： H01L23/4093 , H01L2924/0002 , H01L2924/00
摘要： A heat dissipation structure includes a heat sink having a base formed with four securing tabs laterally extending from four corners of the base. Four positioning posts upwardly protrude from a printed circuit board. Four spring clips are attached to the four positioning posts respectively. Each of the four spring clips has a resilient piece for exerting a downward force to press a corresponding securing tab, thereby securing the heat sink to the printed circuit board.
摘要翻译：散热结构包括散热器，散热器具有形成有从基座的四个角横向延伸的四个固定突出部的基座。四个定位柱从印刷电路板向上突出。四个弹簧夹分别连接在四个定位柱上。四个弹簧夹中的每一个具有弹性件，用于施加向下的力以按压相应的固定突片，从而将散热器固定到印刷电路板。

9. 发明授权

US08426209B2 Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network 有权
标题翻译：用于在微流体通道网络中使用光开关分选细胞的方法和装置
公开(公告)号：US08426209B2
公开(公告)日：2013-04-23
申请号：US12825037
申请日：2010-06-28
申请人： William Frank Butler , Mirianas Chachisvilis , Robert Dees , Norbert Hagen , Philippe Marchand , Daniel E. Raymond , Eugene Tu , Mark M. Wang , Joon Mo Yang , Rong Yang , Haichuan Zhang
发明人： William Frank Butler , Mirianas Chachisvilis , Robert Dees , Norbert Hagen , Philippe Marchand , Daniel E. Raymond , Eugene Tu , Mark M. Wang , Joon Mo Yang , Rong Yang , Haichuan Zhang
IPC分类号： G01N33/48
CPC分类号： G01N15/1459 , B01L3/502707 , B01L3/502761 , B01L3/502776 , B01L2200/0636 , B01L2200/0647 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/0415 , B01L2400/0454 , B01L2400/0487 , G01N2015/149 , Y10T436/2575
摘要： Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on an optical switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of populations of small numbers of cells (i.e., 1000-100,000 cells). The invention includes packaging of the microfluidic channel network in a self-contained plastic cartridge that enables microfluidic channel network to macro-scale instrument interconnect, in a sterile, disposable format.
摘要翻译：为微型荧光激活细胞分选器提供基于光学开关的装置和方法，用于通过微流体通道网络快速，主动地控制细胞路由。该分选机能够对小数量细胞群体（即1000-100,000个细胞）进行低应激，高效分选。本发明包括将微流体通道网络包装在独立的塑料盒中，使得微流体通道网络能够以无菌的一次性格式进行大规模的仪器互连。

10. 发明申请

US20130069297A1 SUPPORTING APPARATUS FOR DISPLAY ASSEMBLY 失效
标题翻译：支持显示装置的装置
公开(公告)号：US20130069297A1
公开(公告)日：2013-03-21
申请号：US13527666
申请日：2012-06-20
申请人： CHIH-HAO YANG , BAO-QUAN SHI , RONG YANG
发明人： CHIH-HAO YANG , BAO-QUAN SHI , RONG YANG
IPC分类号： B25B11/02
CPC分类号： B25B11/02
摘要： A supporting apparatus for assembling a display, includes a supporting bracket. The supporting bracket includes a plate and a restricting arm connected to the plate. The restricting arm includes a connection portion and a restricting portion the restricting. The restricting portion is parallel to the plate to define a restricting space between the restricting portion and the plate. The restricting space receives the display therein. The restricting portion and the plate restricts the display in the restricting space in a first direction which is perpendicular to the plate. A plurality of blocks are movably mounted on the plate. The plurality of blocks restrict the display in the restrict space in a second direction which is parallel to the plate.
摘要翻译：一种用于组装显示器的支撑装置，包括支撑托架。支撑托架包括连接到板的板和限制臂。限制臂包括连接部分和限制部分。限制部分平行于板以限定限制部分和板之间的限制空间。限制空间在其中接收显示。限制部分和板限制在与板平行的第一方向上的限制空间中的显示。多个块可移动地安装在板上。多个块在与板平行的第二方向上限制限制空间中的显示。

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