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1. 发明授权

US11352439B2 Macrophage CAR (MOTO-CAR) in immunotherapy 有权
公开(公告)号：US11352439B2
公开(公告)日：2022-06-07
申请号：US15358395
申请日：2016-11-22
申请人： Kim Leslie O'Neill , Scott Weber
发明人： Kim Leslie O'Neill , Scott Weber
IPC分类号： C07K16/40 , C07K14/705 , C07K14/57 , C07K16/28 , C07K16/18 , C12N5/0786 , A61K35/15 , C07K16/30 , A61K38/00 , A61K39/00
摘要： Modified macrophage immune cells are provided for treatment of cancer and other diseases.

2. 发明申请

US20190091309A1 Use of Car and Bite Technology Coupled with an SCFV from an Antibody Against Human Thymidine Kinase 1 to Specifically Target Tumors 审中-公开
公开(公告)号：US20190091309A1
公开(公告)日：2019-03-28
申请号：US16122563
申请日：2018-09-05
申请人： Kim Leslie O'Neill , Scott Weber
发明人： Kim Leslie O'Neill , Scott Weber
IPC分类号： A61K39/00 , C07K16/28 , C07K16/40 , C07K16/46
摘要： Modified T-cells have paratopes against human TK1 epitopes, are made by producing monoclonal antibodies that are specific to TK1, creating chimeric antigen receptors (CARs) by fusion of the single-chain variable fragments (scFv) of the monoclonal antibodies to T-cell signalling domains, and transducing the CARs to the T-cells.

3. 发明申请

US20170098201A1 ADJUSTING DIFFERENT AREAS OF A PAYMENT INSTRUMENT IMAGE INDEPENDENTLY 审中-公开
公开(公告)号：US20170098201A1
公开(公告)日：2017-04-06
申请号：US15213088
申请日：2016-07-18
申请人： Scott Weber , Rian Maloney
发明人： Scott Weber , Rian Maloney
IPC分类号： G06Q20/04 , G06K9/00
CPC分类号： G06Q20/042 , G06K9/00469 , G06K9/036 , G06K2209/01 , G06Q20/0425
摘要： The present disclosure involves systems, software, and computer-implemented methods for allowing independent adjustment for different areas of a payment instrument image. An example method includes updating an image property of an area of a clearing payment instrument image associated with a tangible payment instrument including a payee, a payor, an amount, and an authorization, the tangible payment instrument to be submitted for electronic transaction clearing, wherein the clearing payment instrument image is associated with a first value of the image property, the image property of the area is updated to a second value different than the first value of the image property, and the area of the clearing payment instrument image includes less than the entire clearing payment image; and storing the updated clearing payment instrument image in response to updating the image property.

4. 发明授权

US09384392B2 Adjusting different areas of a payment instrument image independently 有权
标题翻译：独立调整支付工具图像的不同区域
公开(公告)号：US09384392B2
公开(公告)日：2016-07-05
申请号：US14256471
申请日：2014-04-18
申请人： Scott Weber , Rian Maloney
发明人： Scott Weber , Rian Maloney
IPC分类号： G06K9/00 , G06Q20/04 , G06Q40/00
CPC分类号： G06K9/00463 , G06K9/2081 , G06Q20/042 , G06Q20/0425 , H04N1/44
摘要： The present disclosure involves systems, software, and computer-implemented methods for allowing independent adjustment for different areas of a payment instrument image. An example method includes receiving an original payment instrument image associated with a tangible payment instrument; creating a clearing payment instrument image based on the original payment instrument image associated with a first contrast value; presenting the clearing payment instrument image in a user interface in response to creating the clearing payment instrument image; in response to presenting the clearing payment instrument image: receiving an indication of an area of the clearing payment instrument image from the user interface; receiving an indication of a second contrast value to which to update the indicated area from the user interface; and updating a contrast value of the indicated area of the clearing payment instrument image to the second contrast value.
摘要翻译：本公开涉及用于允许对支付工具图像的不同区域进行独立调整的系统，软件和计算机实现的方法。示例性方法包括接收与有形支付工具相关联的原始支付工具图像; 基于与第一对比度值相关联的原始支付工具图像来创建清算支付工具图像; 响应于创建清算支付工具图像，在用户界面中呈现清算支付工具图像; 响应于提供清算支付工具图像：从用户界面接收清算支付工具图像的区域的指示; 从所述用户界面接收用于更新所述指示区域的第二对比度值的指示; 以及将清算支付工具图像的指示区域的对比度值更新为第二对比度值。

5. 发明授权

US08403265B2 Aircraft cabin door pressure vent system 有权
标题翻译：飞机舱门压力排气系统
公开(公告)号：US08403265B2
公开(公告)日：2013-03-26
申请号：US12874061
申请日：2010-09-01
申请人： Greg Gowing , Scott Weber , Elisabeth Archibald , Shad Plante , Matt Wiley
发明人： Greg Gowing , Scott Weber , Elisabeth Archibald , Shad Plante , Matt Wiley
IPC分类号： B64C1/14
CPC分类号： B64C1/1461 , B64C1/14 , B64C1/1407 , B64C1/143
摘要： Disclosed is an aircraft door including a handle-activated pressure relief system that avoids potentially dangerous pressure differences between the cabin and the atmosphere outside the aircraft. A flow path is created between the inboard and outboard handles on the door. A pressure vent door is located in the flow path. The vent door being is opened when either of the inboard and outboard handle assemblies are activated. Once either handle is rotated beyond a particular point, a spring in the supporting mechanics becomes over-center. At the same time, the vent door comes under the influence of a magnet, snapping the vent open. After the door has been opened, it can be relatched by operating the handles in the reverse direction. The magnet and spring hold the vent door open until the aircraft door is fully latched, sealed, and secured. Only then does the vent door sealingly close.
摘要翻译：公开了一种飞机门，其包括手柄启动的压力释放系统，其避免了机舱和飞机外部的大气之间潜在的危险压力差。在门上的内侧和外侧手柄之间形成流路。压力通风门位于流路中。当内侧和外侧手柄组件中的任一个被启动时，通风门被打开。一旦任一个手柄旋转超过特定点，支撑力学中的弹簧变得越过中心。同时，通风门受到磁铁的影响，将通风口打开。门打开后，可以通过相反方向操作手柄来重新配置。磁体和弹簧将通风门打开，直到飞机门完全锁定，密封和固定。只有这样，通风门密封地关闭。

6. 发明授权

US07331565B2 On/off solenoid 失效
标题翻译：开/关电磁阀
公开(公告)号：US07331565B2
公开(公告)日：2008-02-19
申请号：US10821740
申请日：2004-04-09
申请人： David Mills , Scott Weber , Howard Saxon
发明人： David Mills , Scott Weber , Howard Saxon
IPC分类号： F16K31/02
CPC分类号： F16K31/0631 , F16H61/0251 , F16K31/0665 , Y10T137/86622
摘要： A solenoid control valve is described wherein the valve employs a precision molded plastic valve seat member, a corresponding control valve body which includes flying buttresses for supporting and distributing loads on the control valve body, and armature vent features.
摘要翻译：描述了一种电磁控制阀，其中阀采用精密模制塑料阀座构件，相应的控制阀体，其包括用于支撑和分配控制阀体上的载荷的浮力支撑件和衔铁排气口特征。

7. 发明申请

US20070166751A1 Compositions and Methods for Nucleic Acid Extraction from Biological Samples 审中-公开
公开(公告)号：US20070166751A1
公开(公告)日：2007-07-19
申请号：US11688019
申请日：2007-03-19
申请人： Scott Weber , Derek Douglas , Carol Kreader
发明人： Scott Weber , Derek Douglas , Carol Kreader
IPC分类号： C12Q1/68 , C12N1/08
CPC分类号： C12N15/1003
摘要： Methods and compositions for extracting nucleic acids from a biological sample are provided. The extraction compositions contain a protease enzyme such as proteinase K at alkaline pH with little or no surfactant present. Extraction can be efficiently performed in 60 minutes or less at room temperature for certain mammalian tissue samples and at elevated temperatures for certain plant tissues.

8. 发明授权

US06444960B1 Heading element for charging devices 有权
标题翻译：充电设备的标题元素
公开(公告)号：US06444960B1
公开(公告)日：2002-09-03
申请号：US10045173
申请日：2002-01-11
申请人： Alberto Rodriguez , John Stephen Facci , Heiko Rommelmann , Scott Weber , Joseph David La Russa , Jing Quing Song , Chris Snelling , Kenneth W. Pietrowski
发明人： Alberto Rodriguez , John Stephen Facci , Heiko Rommelmann , Scott Weber , Joseph David La Russa , Jing Quing Song , Chris Snelling , Kenneth W. Pietrowski
IPC分类号： H05B326
CPC分类号： B41J2/41 , G03G15/323
摘要： A method and apparatus for heating a charging unit to an appropriate temperature in a uniform manner is provided. In accordance with one example embodiment of the present invention, a heater for use in a charger includes a base. First and second contacts are disposed on the base. A heating element couples the first contact and the second contact. The heating element has an energy density that increases approximately exponentially from a first energy density at locations distal from the first and second heat sink locations to a relatively higher second energy density at locations proximal to the first and second heat sink locations. The heater, according to further embodiments of the present invention, is disposed on an opposite side of the substrate layer from the AC electrode layer, and underneath the charger.
摘要翻译：提供了一种以均匀的方式将充电单元加热至适当温度的方法和装置。根据本发明的一个示例性实施例，一种用于充电器的加热器包括底座。第一和第二触点设置在基座上。加热元件将第一触点和第二触点相耦合。加热元件的能量密度从远离第一和第二散热器位置的位置处的第一能量密度大致指数地增加到靠近第一和第二散热器位置的位置处的相对较高的第二能量密度。根据本发明的另外的实施例的加热器设置在基底层与AC电极层相反的一侧，并且位于充电器的下方。

9. 发明授权

US6122620A System for the radio transmission of real-time airline flight information 失效
标题翻译：无线电传输系统实时航空公司航班信息
公开(公告)号：US6122620A
公开(公告)日：2000-09-19
申请号：US911641
申请日：1997-08-15
申请人： Christopher Scott Weber
发明人： Christopher Scott Weber
IPC分类号： H04R27/00 , G06F17/60
CPC分类号： H04R27/00 , G06Q10/02 , G06Q10/025
摘要： A flight delivery system that utilizes an architectural structure and network that allows real-time digital signals to be stored, retrieved and converted to an audio signal for radio transmission to achieve nearly instantaneous transmission of real-time data. The system, utilizes a computerized reservation system as a source of information and stores it on a database. The information is called up by a computer that converts the data to a digital audio signal. The digital audio signal is then broadcast over airport antennae. The system features programs that allow for a conversion from airport city codes to the common identification for local cities.
摘要翻译：一种利用架构结构和网络的飞行传送系统，其允许将实时数字信号存储，检索和转换成用于无线电传输的音频信号，以实现实时数据的即时传输。该系统利用计算机化的预订系统作为信息来源，并将其存储在数据库中。信息由计算机调用，将数据转换为数字音频信号。数字音频信号然后通过机场天线广播。该系统具有允许从机场城市代码转换为当地城市的通用标识的程序。

10. 发明申请

US20210330770A1 Use of Car and Bite Technology Coupled with an SCFV from an Antibody Against Human Thymidine Kinase 1 to Specifically Target Tumors 有权
公开(公告)号：US20210330770A1
公开(公告)日：2021-10-28
申请号：US17366708
申请日：2021-07-02
申请人： Kim Leslie O'Neill , Scott Weber
发明人： Kim Leslie O'Neill , Scott Weber
IPC分类号： A61K39/00 , C07K16/46 , C07K16/28 , C07K16/40 , C07K14/725 , A61P35/00
摘要： Modified T-cells have paratopes against human TK1 epitopes, are made by producing monoclonal antibodies that are specific to TK1, creating chimeric antigen receptors (CARs) by fusion of the single-chain variable fragments (scFv) of the monoclonal antibodies to T-cell signalling domains, and transducing the CARs to the T-cells.

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